RepoMed (Medizinische Hochschule Hannover)
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Having a Partner and Having Children: Comparisons of Adults with Congenital Heart Disease and the General Population: a 15-Year Case-Control Study
Get PDFObjectives: To examine whether patients with congenital heart disease (CHD) are less likely to have a partner or children than individuals from the general population. Methods: Longitudinal study with two assessments of the same patients (n = 244) from a hospital population and controls (n = 238) from the German Socio-Economic Panel (GSOEP) using parental education, patients age, and sex as matching criteria. The first patient study was conducted between 5/2003 and 6/2004, the second one between 5/2017 and 4/2019. Controls were drawn from GSOEP-surveys 2004 and 2018. CHD-severity was classified according to type of surgery: curative, reparative, or palliative. Living single was used as outcome measure, for offspring the outcome was having children or not. Results: Among women with CHD the rate of those living single was higher than among controls with the differences depending on disease complexity (curative: OR = 5.5; reparative: OR = 1.9; palliative: OR = 2.7). No statistically significant differences between patients and controls emerged in the male study population. With respect to children a marked difference emerged between women with CHD and controls. Among patients the odds of having children were lower than among controls (curative: OR = 0.3; reparative: OR = 0.3; palliative: OR = 0.2). The rate of patients with children with CHD (women: 5.6%; men: 4.9%) was higher than expected (1%) if compared with the general population. Conclusions: Using partnership and children as outcome criteria, patients with CHD are disadvantaged if compared to subjects from the general population. In female patients the social consequences of the disease turned out as more pervasive than in women
Personalized training as a promoter for physical activity in people with depressive disorder-a randomized controlled trial in Germany
Get PDFIntroduction Adopting an active lifestyle is an important goal, but can be difficult to achieve for people with depressive disorders. Current guidelines recommend the integration of physical activity in the multimodal treatment of depressive disorders. However, the possibilities to provide individual support for physical activities are frequently limited. The aim of our study was to examine how physical activity can be increased in a real-world setting by combining physical training and psychological interventions. Materials and methods In this randomized-controlled interventional study, 31 outpatients diagnosed with moderate to severe depression were recruited from the region of Hannover. The intervention group (n = 16) was offered six weekly individual sessions lasting between 60 and 90 min with a sports scientist, including Motivational Interviewing and accompanied exercise activities. The control group (n = 15) received a written booklet with information on steps toward becoming more active. Moderate-to-vigorous physical activity (MVPA) as the primary outcome was analyzed using activity sensors before and after the 6-week intervention, and 3 months subsequently. Secondary outcomes included the Six-Minute Walk Test (6MWT), Sit-to-Stand test (STS), and mental health assessed with self-rating questionnaires. Results In the intervention group, MVPA increased significantly between baseline and the first follow-up and remained at an increased level at the second follow-up in comparison to decreased levels in the control group (difference of 15.5 min/day between groups over time, SE = 6.2 min/day, 95%-CI[2.7, 28.3], p = 0.020). The increased activity level was associated with markers of increased fitness (6MWT and STS) in the intervention group. Both groups showed comparable improvements in depressive symptoms, while the number of patients receiving antidepressants increased in the control group and decreased in the intervention group. Two patients dropped out of the intervention group during the trial. Conclusion The intervention proved to be a feasible and effective aid to promote a physically active lifestyle for patients diagnosed with depression. Furthermore, the higher level of physical activity was maintained for the follow-up period. Given the success of the approach evaluated in this project, individual support for physical activity should be investigated in larger sample sizes and potentially be considered in the multimodal treatment of depression. Clinical trial registration [https://clinicaltrials.gov/], identifier [DRKS00023257]
Prädiktive Faktoren für messbare Resterkrankung (MRD) nach Chemotherapie bei Patienten mit AML
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Evaluation der Effekte der Patella Pro®-Rezentrierungsorthese bei Patienten mit chronischer lateraler Patellainstabilität mittels eines mobilen Ganganalysesystems in Alltags- und Grenzbelastung: eine Pilotstudie
Get PDFExperimentelle Evaluierung eines knochenzementbasierten Mini-Stereotaxiesystems zur Schaffung eines direkten Zugangs zur Cochlea
Get PDFUntersuchung der zerebralen Sauerstoffsättigung mittels Nah-Infarot-Spektroskopie (NIRS) im Vergleich zum Monitoring mittels Pulsoxymetrie im Rahmen der Sauerstoffmangeldemonstration bei Kammerfahrten am Zentrum für Luft- und Raumfahrtmedizin der Luftwaffe in Königsbrück
Get PDFSDG5 "Gender Equality" and the COVID-19 pandemic: A rapid assessment of health system responses in selected upper-middle and high-income countries.
Get PDFIntroduction The COVID-19 pandemic disrupted healthcare and societies, exacerbating existing inequalities for women and girls across every sphere. Our study explores health system responses to gender equality goals during the COVID-19 pandemic and inclusion in future policies. Methods We apply a qualitative comparative approach, drawing on secondary sources and expert information; the data was collected from March-July 2022. Australia, Brazil, Germany, the United Kingdom, and the USA were selected, reflecting upper-middle and high-income countries with established public health and gender policies but different types of healthcare systems and epidemiological and geo-political conditions. Three sub-goals of SDG5 were analyzed: maternity care/reproductive health, gender-based violence, and gender equality/women's leadership. Results We found similar trends across countries. Pandemic policies strongly cut into women's health, constrained prevention and support services, and weakened reproductive rights, while essential maternity care services were kept open. Intersecting gender inequalities were reinforced, sexual violence increased and women's leadership was weak. All healthcare systems failed to protect women's health and essential public health targets. Yet there were relevant differences in the responses to increased violence and reproductive rights, ranging from some support measures in Australia to an abortion ban in the US. Conclusions Our study highlights a need for revising pandemic policies through a feminist lens
