RepoMed (Medizinische Hochschule Hannover)
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A Prospective Clinical Trial of Prolonged Fasting in Healthy Young Males and Females-Effect on Fatigue, Sleepiness, Mood and Body Composition.
Get PDFFasting during a long period (17-18 h/day) may affect daily performance. Fatigue is one of important parameters to observe for this effect. This study aimed to determine the effect of Ramadan fasting (RF)-particularly on fatigue in both young males and females. Sleepiness, mood-related symptoms (MRSs) and body composition (BC) were determined, too. Thirty-four young males and females were recruited and performed RF. They were assessed for fatigue, sleepiness, MRS and BC at T1 (one week before RF), T2 (mid of RF), T3 (last days of RF), T4 (one week after RF) and T5 (one month after RF). The assessments were done in the morning, except for fatigue and sleepiness, which were also assessed in the afternoon and evening of T1 to T5. This study observed numerous positive effects to RF. After they began fasting and compared to T1, participants experienced (1) significantly less fatigue; (2) small to large improvement of MRSs; and (3) positive changes relating to BC. RF did not appear to have a significant effect on participants' sleepiness scores. Ultimately, this study illustrates how prolonged fasting, like RF, benefits the youth, particularly by decreasing fatigue, improving MRSs and positively impacting BC
Einfluss paroxysmaler vegetativ-sympathischer Hyperaktivität (PSH) auf den Rehabilitationsverlauf neurologischer Frührehabilitanden
Get PDFRisikoeinschätzung von biliären Tumoren: Entwicklung und Validierung eines prognostischen Modells
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Microsurgery Interactive Video Learning Modules: Validierung eines videobasierten Lehrmittels für die Mikrochirurgie
No full textA murine model of FGFR2 fusion driven intrahepatic cholangiocarcinoma to delineate the mechanism of therapeutic response and resistance to FGFR inhibitors
No full textÜberleben pädiatrischer Patienten nach einem Rezidiv einer akuten myeloischen Leukämie nach erster allogener hämatopoetischer Stammzelltransplantation: eine retrospektive I-BFM Untersuchung an 333 Kindern
No full textGeneration of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing.
Get PDFInterferon stimulated gene 15 (ISG15) is one of the most highly upregulated proteins in response to viral infection and is involved in numerous pathways with multiple mechanisms of actions. ISG15 deficiency has been reported to induce type I interferonopathy owing to defective negative regulation of IFN-I signalling as well as enhanced antiviral protection. Here, we have generated ISG15 knockout clones from human iPSCs, which provide useful cell resources to study mechanisms of ISG15 deficiency and gain more insight into the biological function of ISG15