Carolyn Wilson Digital Collections (Lipscomb Univ.)
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Variations in Flexibility Across Menstrual Cycle Phases in Female College Students
No full textTesting flexibility in female college students throughout menstrual cycle; Exercise Scienc
Intersecting Physics and Medicine Through Computed Tomography
No full textComputed Tomography (CT) imaging is a cornerstone of modern medicine. Enabling detailed internal imaging for diagnostic and therapeutic applications. This project explores the physics underlying CT imaging, highlighting how fundamental principles of physics integrate seamlessly with medical advancements. We will examine X-Ray generation, attenuation, and image reconstruction, demonstrating how varying tissue densities influence scan results. The role of mathematical algorithms, such as filtered back protection and iterative reconstruction, will be discussed in relation to image clarity and radiation does optimization.
Additionally, we will address the balance between image resolution and patient safety, emphasizing the importance of minimizing radiation exposure while maximizing diagnostic accuracy. By analyzing real CT scan data and reviewing case studies, this project will showcase the indispensable connection between physics and medicine. Through this exploration, we aim to illustrate how advancements in physics contribute directly to medical innovation, ultimately improving patient care and diagnostic precision
Prosperity Gospel Orientation Interacts with Life Stress to Impact Religious Doubt and Psychological Well-being
No full textProsperity gospel beliefs (PGB) assert God wants believers to prosper on earth and will reward the faithful with health and financial success. Wilkinson and Biondolillo (2021) developed the Prosperity Gospel Belief Scale, finding relationships with religiosity, prayer, attachment to God, materialism, greed, and entitlement. This study examines whether PGB and stress interact to increase religious doubts (RD) and decrease psychological well-being (PWB), measured by life satisfaction (LS), positive affect (PA), and negative affect (NA). Participants were recruited from psychology courses and completed study questionnaires using an online platform, with all procedures approved by the Lipscomb University IRB. Seventy-nine participants (Mage = 19.51; 74.7% female; 100% Christian) completed all measures. ANOVAs were conducted using RD, LS, PA, and NA as dependent variables and PGB and stress as independent variables. The ANOVA for RD was significant (F(3, 75) = 4.88, R2 = 0.16), with main effects for stress (F(1, 75) = 9.30) and PGB (F(1, 75) = 5.95), but no interaction. The ANOVA for LS was significant (F(3, 75) = 5.01, R2 = 0.17), with main effects for stress (F(1, 75) = 4.57) and PGB (F(1, 75) = 8.80), and a significant interaction (F(1, 75) = 3.43). The ANOVA for PA was significant (F(3, 75) = 3.24, R2 = 0.12), with a significant interaction (F(1, 75) = 6.32), but no significant main effects. The ANOVA for NA was not significant. These findings partially confirm the study hypotheses, particularly for LS and PA
Antigone in Munich Scene Performance
No full textIn this presentation, two actors will portray the roles they played in a student production of Antigone in Munich for Lipscomb University Theatre\u27s MainStage productions. The performance, which includes a combination of scenes from the play, will capture for audiences a feel of the show and the production team\u27s vision
Levels of Beta Catenin with Treatment of HD5 in IEC-6 Rat Cells
No full textHuman Defensin 5 (HD5) is an antimicrobial peptide present in the small intestine that plays a role in gut homeostasis. We have been investigating the role of HD5 in colon cells, but research shows that HD5 levels in the small and large intestine vary significantly in Crohn\u27s. Previous data from our lab suggests that HD5 leads to a decrease in wound healing and an increase in apoptosis in colon cells, we want to see if the same is true in the small intestine. So, we are investigating the effect of HD5 on expression of β-catenin, a key protein in the Wnt signaling pathway, in IEC-6 rat small intestinal epithelial cells. We hypothesize that HD5 promotes wound healing and enhances β-catenin expression in IEC-6 cells. To test this, we cultured IEC-6 cells and performed a wound closure assay to compare wound healing between the vehicle control and experimental groups - 0.5 ug/mL, 1.0 ug/mL, and 2.0 ug/mL of HD5. We then extracted protein and RNA to perform a Western Blot and q-RT-PCR for expression analysis. The rate of wound closure between both treatment groups could not be observed. We saw an increase in β-catenin in HD5-treated cells on our western blot (though not statistically significant) and expect a positive fold change for β-catenin in our q-RT-PCR experiment. Future studies will focus on investigating β-catenin expression in colonic epithelial cells treated with HD5 as a possible mechanism for decreased wound closure in Crohn\u27s Colitis
In pregnant women, what is the effect of nutritional guidance and intervention on maternal and fetal health outcomes compared with standard or no nutritional counseling within the prenatal and postpartum period?
No full textGaylord Opryland Congestion Reduction
No full textLipscomb University’s College of Engineering is working collaboratively with Gaylord Opryland Resort and Convention Center to explore potential solutions to its traffic congestion problem, particularly during peak times such as the holiday season. This research aims to identify strategies that can alleviate congestion in the resort area. With over one million visitors during the holiday season each year and limited parking capacity, the traffic congestion poses a significant challenge to both operational efficiency and visitor experience. The primary objective of this research is to identify strategies that optimize parking usage, reduce congestion, and improve the overall visitor experience. Beginning with a literature review on traffic management innovations, focusing on ride-pooling, visitor behavior, and smart parking systems, three peer-reviewed articles were selected to explore the effectiveness of those strategies in high traffic areas. Primary data was collected through site visits where the flow of traffic, utilization of parking, and visitor behavior was analyzed in real-time. The findings will identify the key points where bottlenecks occur, which can help inform potential solutions. Ultimately, the goal of this study is to propose practical strategies to help alleviate traffic congestion at Opryland, particularly during peak tourist seasons
The Nesting Behavior and Habitat Selection of Wood Thrushes
No full textWood Thrushes (Hylocichla mustelina) are a species of concern in Tennessee due to many factors. Historically, their nests have been found in low-hanging branches at the edge of dense forest (Evans et al. 2020). In 2021, a Wood Thrush nest was found in Warner Parks, a 3100-acre urban park sixteen kilometers south of Nashville, TN nesting eighteen meters off the ground and thirty meters from an active trail. We wanted to learn if this unusual nest height was a common occurrence in an active area of Warner Parks or an anomaly. We decided to compare nesting behavior and habitats at Warner Parks with Timberland Park, a low-traffic 72-acre park in Williamson County, TN. From May through July of 2024, we searched Timberland Park and the Warner Parks for Wood Thrush nests using binoculars and listening for vocalizations. The nest heights in Warner Parks ranged between 11.8 to 18.3 meters above the ground with an outlier of 1.5 meters (n = 5). Nest heights of Timberland ranged between 2.1 to 11.8 meters above the ground (n = 3). Our observations suggest nest height may be affected by human presence in urban parks
Elucidating the Role of HD5 in Colonic Wound Healing
No full textCrohn’s colitis (CC), a subtype of inflammatory bowel disease (IBD), causes chronic inflammation in the large intestine, leading to malnutrition, diarrhea, and severe pain. Early and accurate diagnosis of CC is crucial, as misdiagnosis with ulcerative colitis (UC) can result in inappropriate treatment and worsened outcomes. The innate immune peptide human alpha-defensin 5 (HD5) is upregulated in CC but not in UC, suggesting a potential role in disease pathogenesis. Preliminary data from our lab indicates that HD5 impairs wound healing in colonic epithelial cells, but the molecular mechanisms remain unclear.
Hypothesis We hypothesize that HD5 increases RNA and protein levels of COL4A3, EGF, and MMP1 while decreasing ACTB expression, thereby affecting colonic wound healing in CC.
Methods Wound healing assays will assess the effect of HD5 on epithelial cell migration and closure. RNA and protein extractions will be performed on HD5-treated NCM460 cells, followed by qPCR and Western blot analyses to measure gene and protein expression levels of COL4A3, EGF, MMP1, and ACTB.
Expected Results We anticipate that HD5 treatment will reveal altered expression of genes and proteins essential to wound healing. These findings will provide insight into HD5’s role in CC pathogenesis and identify potential molecular targets for therapeutic intervention. This study aims to enhance the understanding of HD5’s influence on epithelial repair and its contribution to CC, ultimately guiding more effective treatment strategies
