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Lung Ultrasound-based Artificial Intelligence Prediction of Congestive Heart Failure Readmission
No full textAmerican Thoracic Society International Conference, ATS 2025, May 16 - 21, 2025, San Francisco, C
Expansion of Hand Trauma Transfers at a Level 1 Trauma Center Following Integration with the ASSH Hand Trauma Center Network
No full textPurpose: This study sought to evaluate how joining the National Hand Trauma Center Network (NHTCN) affected the volume, demographics, and severity of hand trauma transfers to our institution. Methods: Data for this study were collected retrospectively over a 6-year period from 2016 to 2021 from our institutional trauma registry. Patients were selected based on the criterion of being transferred to our facility because of isolated hand trauma. Analyses of transfer rates, transfer distance, sending facilities, injury patterns, insurance type, path of care, and hospital charges prior to and after joining the NHTCN were performed. Results: There was a total of 39 transfers with isolated hand trauma over 3 years prior to joining the NHTCN, and 114 over 3 years after. The average number of hand transfers per year increased by 25, with an increase in both in-state and out-of-state transfers. This included an increase in transfers of serious injuries including complete amputations, open devascularization injuries, and open fractures. The average distance traveled by transfers increased by 22.6 miles. The demographics and insurance coverage of transfers were similar. The overall average charge per person increased from 33,663. Admissions of transfers decreased by 27.3%. The percentage of transfers undergoing surgery or receiving specialized hand care in the ED increased from 66.7% to 91.2%. Conclusions: Integration into the NHTCN increased our institution\u27s volume of hand trauma transfers, with patients transferred from additional referring facilities, some of which were further from our center. Clinical relevance: These findings suggest that joining the NHTCN increased regional patient access to specialized hand surgical care. There was an overall increase in the quantity of severe injuries treated; however, there were only small shifts in the overall composition of transfers
Interplay between admission and early postpartum blood pressure and risk of postpartum readmission for hypertension
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Contingency Management With Stepped Care for Unhealthy Alcohol Use Among Individuals With HIV: Initial Findings From a Multisite Randomized Controlled Trial.
No full text2024 Annual Meeting of the College on Problems of Drug Dependence; June 16 - 19, 2024; Montreal, CA
The lungs of the finch: three-dimensional pulmonary anatomy of the zebra finch (Taeniopygia castanotis)
Get PDFThe avian respiratory system has been an area of biological interest for centuries, with zebra finches (Taeniopygia castanotis) emerging in recent decades as a primary avian model organism popularized across numerous disciplines. The pulmonary system of birds is unique in that air moves unidirectionally through the gas-exchanging lung, and previous works have suggested anatomical constraints within the bronchial network that may be coupled to the inspiratory valving mechanism in Aves. We used µCT-based segmented models to visualize and describe the morphology of the zebra finch lower respiratory system and to examine intra- and interspecific differences of the bronchial tree with the phylogenetically and ecologically different African grey parrot (Psittacus erithacus). Here, we show that zebra finches have highly variable lung and air sac morphology within individuals but generally do not diverge from the anatomical bauplan previously described for passerines. Additionally the parabronchi in the zebra finch lung are arranged into isolated segments between secondary bronchi, which has not been described and may be coupled with airflow patterns in this species. Both zebra finches and African grey parrots show constrained interostial distances and robust, caudally directed third ventrobronchi that may play an unexplored role in the unidirectional airflow patterns of birds.This article is part of the theme issue \u27Biology of the avian respiratory system: development, evolutionary morphology, function and clinical considerations\u27
Summary from the NCI clinical trials planning meeting on next generation of clinical trials in non-muscle invasive bladder cancer
Get PDFThe National Cancer Institute organized a virtual Clinical Trials Planning Meeting (CTPM) on \u27Defining the next generation of clinical trials with combination therapies in non-muscle invasive bladder cancer (NMIBC)\u27 led by the Bladder Cancer Task Force of the NCI Genitourinary Cancers Steering Committee. The purpose of this meeting was to accelerate advances in clinical trials for patients with high-risk NMIBC. The meeting delivered a multidisciplinary expert consensus on optimal strategies for next-generation clinical trial designs in NMIBC with prioritization of combination therapies. Two clinical trial concepts were developed for potential implementation within the National Clinical Trials Network
Bilateral Carotid Body Paragangliomas With Succinate Dehydrogenase Complex Subunit D Gene Mutation
Get PDFPost-Market Study Evaluating Performance of the Rechargeable InterStim™ Micro System in Fecal Incontinence Patients
No full textIntroduction and Hypothesis: To confirm the performance and safety of the rechargeable sacral neuromodulation system (InterStim™ Micro) through 2-year follow-up, we report results from the fecal incontinence (FI) cohort through 6-month follow-up. Methods: Eligible patients were enrolled following successful therapy evaluation and implant. Participants completed bowel diaries and questionnaires at baseline, 3, and 6 months post-implant. The primary objective was improvement in Cleveland Clinic Incontinence Score (CCIS) at 3 months post-implant compared to baseline. Safety was evaluated by collection of reportable adverse events (AE). Results: Of 53 patients implanted, 90.6% were female and the mean (± SD) age was 58 ± 11 years. There was a statistically significant improvement in CCIS at 3 months vs baseline, with a mean change of −4 ± 3.7 (p \u3c 0.001, n = 52). This improvement was maintained at 6 months, with a mean change of −4.0 ± 3.58 (n = 52). The mean change in Fecal Incontinence Quality of Life (FIQoL) at 3 months was 3.2 ± 2.8 (n = 52) and 3.6 ± 2.9 (n = 53) at 6 months. On the Patient Global Impression of Improvement (PGI-I), 94% (n = 52) and 90.6% (n = 53) of participants reported their condition was better at 3- and 6-month follow-up compared to baseline, respectively. The incidence of device-, procedure-, or therapy-related AEs in enrolled participants was 18.9% (10/53); among these was one serious related AE. There were no unanticipated adverse device effects. Conclusions: The primary objective of the FI cohort was met, with statistically significant improvement in CCIS and patient-reported outcomes. These data confirm clinical performance and safety through 6 months post-implant. Clinical trial registration: NCT04506866