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Pembrolizumab-induced Reactivation of ANCA-associated Vasculitis Presenting With Hemoptysis and Pauci-immune Glomerulonephritis in a Patient With Metastatic Non-small Cell Lung Cancer
No full textAmerican Thoracic Society International Conference, ATS 2025, May 16 - 21, 2025, San Francisco, C
BRIEF - From Potholes to Perceived Social Support: Community Influences on Individuals with Mobility Disabilities and their Care Teams in New Orleans
No full textOptimization of Spinal Cord Perfusion Pressure for Improvement of Neurological Outcome in Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis
No full textThe optimal hemodynamic management of traumatic spinal cord injury (tSCI) is not well established. We performed a systematic review and meta-analysis of patients with acute tSCI to assess the role of lumbar cerebrospinal fluid drainage (CSFD) and to identify factors predictive of neurological improvement. Three studies involving 46 patients with acute tSCI, lumbar drain placement with CSFD, and available pre- and post-intervention American Spinal Injury Association (ASIA) Impairment Scale or International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) motor scores were identified. One study was analyzed separately (Cohort A) using ASIA grade because post-intervention ISNCSCI motor scores were not reported. In the remaining two studies (Cohort B), two independent meta-analyses with meta-regressions were performed to determine the mean difference in ISNCSCI motor scores by CSFD and time to decompression. Individual patient data were used for all analyses. In Cohort A, there was no significant difference in ASIA grade before lumbar CSFD and at the last follow-up (Wilcoxon signed rank test: p = 0.130). In Cohort B, female sex and anterior decompression were associated with greater neurological recovery compared with male sex (p = 0.045) and a combined approach to decompression (p = 0.048), respectively. There were no other significant indicators of better motor scores in either cohort. CSFD with a target intrathecal pressure, rather than volume restrictions, may allow for sufficient fluid drainage to maximize spinal cord perfusion pressure (SCPP). Patients may benefit most from individualized management of SCPP because of the wide variance in interpatient and chronological intrathecal pressure
Gold, Green, and Everything Inbetween
No full textCome learn about Open Access publishing routes to better equip yourself to navigate the changing scholarly publishing landscape. You’ll learn how publishers are responding to updated NIH and other funder requirements. We’ll discuss LSUHSC’s current fee waiver agreements to help you avoid additional publishing costs
Humoral Response against Epstein-Barr Virus Among Healthy Individuals Follows a Strain-specific and HIV-Driven Pattern
No full textChronic-Plus-Binge Alcohol Exposure Promotes Vascular Stiffness and Diastolic Dysfunction in Aging Mice
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