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WHEN THE PODIUM IS NOT ENOUGH: THE SUPPLY AND CONSUMPTION OF CONTENT ON THE PARIS 2024 PARALYMPIC GAMES
No full textO objetivo geral do estudo foi investigar se – e de que forma – estudantes de Educação Física consumiram conteúdos dos Jogos Paralímpicos (JP) Paris 2024 e quais fatores influenciaram esse consumo. Também comparamos padrões e fontes de consumo de transmissões de competições e de outros conteúdos relacionados aos Jogos Olímpicos (JO) e aos JP. Verificamos que o consumo dos JP foi significativamente menor e fortemente dependente de redes sociais, uma vez que o Grupo Globo, detentor dos direitos de transmissão, não divulgou efetivamente o evento, restringindo o acesso aos conteúdos. Concluímos que os Comitês Paralímpicos e seus parceiros precisam revisar os modelos de concessão e adotar estratégias integradas, com transmissões acessíveis, tradução simultânea e presença ampliada em plataformas digitais utilizadas pelos jovens, garantindo maior alcance e visibilidade.The main objective of this study was to investigate whether – and how – Physical Education students consumed content related to the Paris 2024 Paralympic Games (PG) and which factors influenced this consumption. We also compared patterns and sources of consumption of competition broadcasts and other content related to the Olympic Games (OG) and the PG. We found that PG content consumption was significantly lower and strongly dependent on social media, since Globo Group, the broadcasting rights holder, did not effectively promote the event, thereby restricting access to the content. We conclude that the Paralympic Committees and their partners need to revise broadcasting models and adopt integrated strategies, including accessible transmissions, simultaneous translation, and an expanded presence on digital platforms used by young people, ensuring greater reach and visibility
MidiAto 15+: a path of many directions
No full textEditorial (v. 19 / n. 38)Editorial (v. 19 / n. 38)
The influence of governance on the capital structure of SMEs in the local apparel productive arrangement
No full textPurpose
This study examines how governance mechanisms influence the capital structure of small- and medium-sized enterprises (SMEs) within the Local Apparel Productive Arrangement of the Hinterlands of Pernambuco.
Design/methodology/approach
By analyzing the governance in mitigating informational asymmetry, this study investigates its impact on credit access. A non-parametric Mann–Whitney test was employed to compare report production between companies that obtained bank loans and those that did not. Additionally, a structural equation model is applied to assess the relationship between governance adoption and credit accessibility.
Findings
The results indicate that firms with bank loans produce more reports, suggesting a positive link between transparency and financial credibility. Moreover, governance adoption reduces informational asymmetry and facilitates credit approval.
Originality/value
This study contributes to literature by providing empirical evidence on the effects of governance mechanisms on SMEs’ capital structure of SMEs. The findings offer practical insights for entrepreneurs, enabling them to evaluate appropriate governance structures to enhance their financing decisions. Furthermore, the results support policymakers in designing strategies for improving SMEs’ access to debt financing. By emphasizing the role of governance in SMEs, this study underscores its importance in strengthening management quality and financial decision-making. Increased transparency can enhance the trust between companies and financial institutions, ultimately fostering sustainable business growth
Notch2 is involved in regulating apical tissue repair following severe intrusive luxation
No full textThis study aims to characterize apical repair dynamics in immature permanent teeth after severe intrusive luxation, and to explore Notch signaling pathway regulation in this process using a Sprague-Dawley rat model. Methodology In this study, a modified tool was utilized to establish an intrusive luxation model in SD rats. Tissue repair was assessed via micro-computed tomography (Micro-CT) and hematoxylin-eosin (H&E) staining. Differential gene expression analysis of stem cells from the apical papilla (SCAPs) was performed using the publicly available GEO dataset. Immunohistochemical detection of Notch2 receptor expression in the apical region of injured teeth was subsequently conducted, guided by bioinformatics screening. Finally, the Notch signaling pathway was pharmacologically inhibited using DAPT (γ-secretase inhibitor), and its impact on post-injury prognosis was evaluated. Results Histological analysis revealed prevalent pulp hypoplasia and apical tissue fibrosis after injury. Differential gene analysis suggested that the Notch signaling pathway, particularly Notch2, is involved in the regulation of angiogenesis-related pathways in SCAPs. Immunohistochemistry showed positive Notch2 expression in fibrotic apical regions. Notably, inhibition of Notch signaling significantly reduced aberrant fibrosis while enhancing vascular proliferation in the injury site. Conclusions Severe intrusive luxation is primarily characterized by aberrant fibrous differentiation in the apical region. The Notch signaling pathway may negatively regulate angiogenesis in the damaged apical area, suggesting that targeted inhibition of this pathway could promote tissue repair following embedded dental injuries
Bond strength in class V cavities: an in vitro study on beveling, universal adhesive strategy, and composite type
No full textCervical Class V lesions present restorative challenges due to their multifactorial etiology and complex bonding substrates. Objectives: This study evaluated the influence of marginal bevel, bonding using a universal adhesive (etch-and-rinse or self-etch), and the resin composite type (conventional or bulk-fill) on the bond strength of simulated Class V cavities. Methodology: A total of 80 dental fragments (7mm×7 mm×2 mm) were obtained from bovine incisors. Cylindrical cavities with enamel margins and internal dentin walls were prepared centrally in each specimen. Samples were randomly assigned to groups based on three factors: presence or absence of bevel, bonding strategy (etch-and-rinse or self-etch), and resin composite type (conventional or bulk-fill). Groups with bevel received a 1 mm enamel bevel along the preparation margins using a conical diamond bur. Adhesive and restorative procedures were performed following the manufacturer’s recommendations. Bond strength was assessed using a push-out test on a universal testing machine. Data were analyzed using three-way ANOVA and Tukey’s post-hoc test (α=5%). Results: Presence of a marginal bevel did not significantly influence bond strength. The etch-and-rinse bonding strategy resulted in significantly higher bond strength than the self-etch approach, and bulk-fill composites presented superior performance compared with conventional composites. Conclusions: Combining a universal adhesive applied with the etch-and-rinse strategy and a bulk-fill composite proved to be an effective approach for enhancing bond strength with enamel and dentin substrates. Beveling of enamel margins did not improve the bond strength of Class V restorations, suggesting that this procedure may be unnecessary when margins are in enamel. Avoiding beveling in such situations contributes to preserve sound tooth structure and supports a more conservative restorative approach
Effects of live and heat-killed Bifidobacterium lactis in rats with induced periodontitis
No full textBackground Probiotics and postbiotics have emerged as promising adjunctive therapies in managing periodontal disease. Bifidobacterium animalis subsp. lactis HN019 has shown antimicrobial and immunomodulatory effects in both experimental and clinical settings when administered orally. However, the systemic impact of this strain, independent of local oral effects, remains unclear.
Objective To evaluate the systemic effects of live and heat-killed B. animalis subsp. lactis HN019 in a rat model of ligature-induced periodontitis, excluding direct contact with the oral cavity. Methodology A total of 32 Wistar rats were randomly assigned to four groups (n=8): control (C), periodontitis only (EP), periodontitis + probiotic (PRO), and periodontitis + postbiotic (POS). Periodontitis was induced by placing a cotton ligature around the cervical region of the lower right first molar, inserted into the gingival sulcus. Treatments were administered via oral gavage for 30 days before and 15 days after periodontitis induction. Alveolar bone loss and periodontal parameters were assessed using micro-computed tomography (microCT) and histomorphometric analysis. Results MicroCT revealed that ligature effectively induced periodontitis, reducing BV/TV and Tb.N and increasing Tb.Sp and Po.Tot. Probiotic and postbiotic treatments did not improve outcomes. Bone loss was lowest in the control group, with no differences between EP, PRO, and POS. Conclusion Systemic administration of Bifidobacterium animalis subsp. lactis HN019 or its derived postbiotic resulted in no significant improvements in periodontal outcomes in this experimental model. Further investigations using integrative approaches are needed to better characterize the systemic effects of probiotics and postbiotics
Pagodocerus, a new beetle genus of Mastigocoleidae from mid-Cretaceous Kachin amber (Coleoptera: Dryopoidea)
No full textMastigocoleidae are an extinct beetle family known from only a few Cretaceous deposits. Here, we describe Pagodocerus volkovitshi gen. et sp. nov., a new mastigocoleid species preserved in mid-Cretaceous Kachin amber. Pagodocerus is primarily distinguished from all other beetles by its asymmetrically perfoliate antennae, with flagellomeres pronouncedly tapering apically. This discovery expands the known diversity of Mastigocoleidae and enhances our understanding of this rare beetle lineage.Mastigocoleidae are an extinct beetle family known from only a few Cretaceous deposits. Here, we describe Pagodocerus volkovitshi gen. et sp. nov., a new mastigocoleid species preserved in mid-Cretaceous Kachin amber. Pagodocerus is primarily distinguished from all other beetles by its asymmetrically perfoliate antennae, with flagellomeres pronouncedly tapering apically. This discovery expands the known diversity of Mastigocoleidae and enhances our understanding of this rare beetle lineage
HIV-associated neurological infections in a Brazilian tertiary care center: clinical-epidemiological features and predictors of in-hospital mortality
No full textNeurological manifestations remain a significant cause of hospitalization and in-hospital mortality among people living with HIV (PLWH), even in the era of antiretroviral therapy (ART). This study aims to describe the clinical and epidemiological profile of PLWH with neurological opportunistic infections (nOIs) and to identify factors associated with in-hospital mortality. We conducted a retrospective cohort study with PLWH aged >18 years hospitalized due to nOIs between November 2017 and December 2021 at a tertiary hospital in Brazil. Demographic, clinical, and laboratory data were extracted from electronic medical records. Logistic regression was used to evaluate associations between patient characteristics and in-hospital mortality. Among 237 hospitalized PLWH, 89 (37.6%) had nOIs. The median CD4 count at admission was 55 cells/mm³ (IQR 22.5–149), and 91.7% had previously used ART (only 22.7% used it regularly). The most frequent infections were cerebral toxoplasmosis (50.6%), cryptococcal meningitis (10.1%), and progressive multifocal leukoencephalopathy (9%). A total of 19 in-hospital deaths occurred. In the multivariate analysis, undefined neurological infections (aOR: 8.67; 95%CI: 1.23–61.17) and ICU admission (aOR: 58.61; 95% CI: 10.24–335.49) were independently associated with mortality. In conclusion, severe immunosuppression and low ART adherence were common in this cohort. Cerebral toxoplasmosis was the most prevalent neurological infection. ICU admission and undefined neurological syndromes were strong predictors of in-hospital mortality. Early diagnosis, prompt treatment, and strategies to improve ART adherence are essential to reduce fatal outcomes in this population
La inteligencia artificial como aliada del Proceso de Enfermería: caminos y consideraciones éticas
No full textBetween law and reality: how integrating referral services andprimary health care can strengthen care for legal abortion
No full textThis article analyzes the comprehensiveness ofhealth care in the context of legal abortion inBrazil, highlighting challenges and advances inguaranteeing this right, focusing on Primary HealthCare (PHC) and specialized services, such as theCenter for Comprehensive Care for Victims of SexualAssault (NUAVIDAS). It presents how this serviceoperates and innovative aspects in the care provided tocases of sexual violence and legal abortion followingviolence, such as the adoption of the telehealth modelduring the pandemic, which expanded access to safeabortion. NUAVIDAS still faces challenges due to thelack of specialized services and weak coordinationwith primary care. Despite legal support, barriersto the implementation of the right to legal abortionpersist, contributing to the maintenance of unsafeabortions and inequalities in access to reproductivehealth. The article proposes strategies for integrationbetween PHC and specialized services, with theexpansion of telehealth and regulation of care flowsfor greater access and effectiveness in care. Althoughthere has been progress, fully guaranteeing legalabortion requires a strengthened health system,consolidated regulations, and evidence-based publicpolicies, aligned with the principles of the UnifiedHealth System (SUS), within the framework of sexualand reproductive rights and reproductive justice.O artigo analisa a integralidade do cuidado em saúde no contexto do aborto legal no Brasil, destacando desafios e avanços na garantia desse direito, com foco na Atenção Primária à Saúde (APS) e em serviços especializados, como o Núcleo de Atenção Integral a Vítimas de Agressão Sexual (NUAVIDAS). Apresenta o funcionamento desse serviço e aspectos inovadores na atenção aos casos de violência sexual e aborto legal pós-violência, como adoção do modelo de telessaúde durante a pandemia que ampliou o acesso ao aborto seguro. O NUAVIDAS ainda enfrenta desafios pela insuficiência de serviços especializados e fragilidade na articulação com a atenção primária. Apesar do amparo legal, persistem barreiras para a efetivação do direito ao aborto legal, contribuindo para a manutenção de abortos inseguros e desigualdades no acesso à saúde reprodutiva. O artigo propõe estratégias para integração entre APS e serviços especializados, com expansão da telessaúde e regulamentação de fluxos assistenciais para maior acesso e efetividade no atendimento. Embora haja avanços, a plena garantia do aborto legal exige um sistema de saúde fortalecido, normativas consolidadas e políticas públicas baseadas em evidências, alinhadas aos princípios do Sistema Único de Saúde (SUS), no marco dos direitos sexuais e reprodutivos e da justiça reprodutiva