Central Asian Journal of Medical and Natural Science
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Assessment of Changes in Hormonal Levels in Women with Menstrual Dysfunction Who Suffer from COVID-19
No full textAccording to the World Health Organization, the COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 620 million infections and 6.5 million deaths worldwide as of September 2022 [1]. Over the past few years, the COVID-19 pandemic has had a significant impact on the health and lives of people around the world. Numerous retrospective studies have shown that age is a critical factor affecting the prognosis of patients with COVID-19 (Guan et al., 2020). Additionally, gender is believed to play an important role in the progression of COVID-19, as female patients have a better prognosis (Chen et al., 2020). Similarly, some infectious diseases, such as MERS and SARS, have mild clinical symptoms and better outcomes in women of childbearing age (Alghamdi et al., 2014; Karlberg et al., 2004). Researchers have been studying COVID-19 since day one, and there is already robust data on the effects of infection with the SARS-CoV-2 virus on the respiratory [2], circulatory [3] and nervous systems [4]. However, little is known about the impact of COVID-19 on the reproductive system, especially the female reproductive system. The impact of the COVID-19 pandemic on the female reproductive system and changes in the menstrual cycle have been widely reported anecdotally and in the media [5]
L. Serriola's Protective Impact on Lung Histology Against Benzo(A)Pyrene-Induced Carcinogenesis in Mice
No full textNatural plants are considered an important factor in human resistance to diseases. This study aimed to evaluate Protective effect of L. serriole on histological features of Lungs induced by a carcinogen benzo (a) pyrene. The histological study of the lungs of mice showed that there were significant changes in the normal liver structure in the group of animals that took doses of the carcinogenic substance benzo(a)pyrene, which caused damage to the lung tissue. A disease in the normal structure of the lung tissue in a normal way. The results of the histological diagnosis of the lung showed the presence of hyperemia at the concentration dose of 0.003 mg/kg. When the concentration was given at 0.0015 mg/kg, it was found that there were histological changes, infiltration of inflammatory cells, compared to the control group .The results of changes in the measurements of internal parameters of the lungs in the group that was taken with a carcinogen benzo(a)pyrene only showed a significant increase at the level of probability 0.05 in the average measurements of the internal parameters of the alveoli and bronchi, while the results of the dose of alcoholic extract of wild beer lettuce showed a concentration of 0.006 mg/kg, 0.003 mg/kg, and 0.0015 mg/kg showed a slight increase at a probability level of 0.05 compared to the control group.
 
The Importance of Uric Acid in the Development of Cardiovascular Diseases
No full textCardiovascular disease (CVD) is a common name for diseases of the heart and blood vessels. Currently, these diseases are one of the main causes of death and disability worldwide. Currently, several studies have emphasized hyperuricemia as an independent risk factor for CKD. According to the literature, hyperuricemia occurs in 2% of the US population, 17% in France, 7% in Spain, and 19.3% in Russia. This article provides information on the importance of uric acid in the development of cardiovascular diseases
Impact of IL-37 on Oxidant-Antioxidant Status in Chronic Liver Failure
No full textChronic liver failure, characterized by the permanent and gradual loss of liver function over time, is influenced by oxidative stress and inflammation. This study aimed to evaluate the association between interleukin-37 (IL-37) and oxidant-antioxidant status in patients with chronic liver failure, given that IL-37 is activated by reactive oxygen species (ROS). Conducted at Al-AL-Hussein Teaching Hospital in Thi-Qar governorate from August 20, 2023, to February 25, 2024, the study involved 40 patients and 40 controls aged 20 to 60. Blood samples were collected and analyzed using ELISA and other biochemical methods. Results indicated significantly higher levels of IL-37, malondialdehyde (MDA), and ceruloplasmin (Cp) in patients compared to controls (P < 0.05), while levels of albumin, glutathione (GSH), and superoxide dismutase (SOD) were significantly lower. A positive correlation was found between IL-37, MDA, and Cp, whereas a negative correlation was observed between IL-37 and albumin, GSH, and SOD. These findings suggest that IL-37 may play a role in the oxidative stress observed in chronic liver failure, highlighting potential targets for therapeutic intervention
Correlation Between Vitamin D Deficiency and Hyperglycemia
No full textDiabetes is a chronic condition affecting the body's use of food as fuel and poses significant health risks during pregnancy for both women and their unborn children. Abnormalities in vitamin D synthesis and metabolism are associated with calcium metabolic diseases. This study aimed to investigate the relationship between vitamin D3 levels and diabetes. Blood samples from 60 participants, including 50 with hyperglycemia and 10 controls, were analyzed for HbA1c, fasting blood sugar, and vitamin D3 levels. Results indicated that diabetic participants had significantly lower vitamin D3 levels compared to the control group. The findings suggest that low vitamin D3 levels may contribute to higher blood sugar levels in diabetic patients, highlighting the importance of monitoring and managing vitamin D3 levels in this population
Evaluation of Drinking Water Reverse Osmosis in the City of Al-Nasiriyah Using Bioassay
No full textThe quality of drinking water is a priority in most countries. Drinking water is crucial for food production and must be free from harmful substances, while also having a composition that is beneficial to health (Cybulski et al., 2021). The research problem is represented by the low quality of drinking water in Reverse Osmosis (RO) drinking water filtration stations, represented by its physical and chemical characteristics in the city of Al-Nasiriyah and its impact on the general health of the city’s residents. Given the importance of RO drinking water used within a wide segment, the current study aims to evaluate the toxicity of water with chemical pollutants and its suitability for drinking for residents of the city of Al-Nasiriyah using the bioassay method.
To obtain toxicological results for this water in the current study in the city of Nasiriyah and at the various water filtration stations, samples were taken from water distributors in six different areas in the city of Al-Nasiriyah in 2024, which are Al-Shuhada, Al-Shumukh, Industrial Housing, Al-Salihiyah, Al-Rafidain, and Al-Mutnazah ) which are brought from stations. Toxicity, both acute and cumulative, was recorded in almost all samples, but the highest was at station 4 (Al-Abada station) in the Salhiya area, where the percentage of coefficient deviation from the growth rate was (88.23%) after 24 hours and (88.33%) after 96 hours, with a stimulating effect. This may be due to the presence of high concentrations of nutrients such as phosphates and nitrates in the aforementioned station, or as a result of water pollution during its distribution. While toxicity was recorded with an inhibitory effect in samples (1,2,3), but with a percentage of deviation coefficient lower than what was recorded in station (4), while station (6,5) was the least toxic station. The current results indicate the need to pay attention to stations for filtering and treating drinking water because they do not conform to the standard specifications for drinking water due to the dependence of a large number of the population on them. 
Study of Erythropoietin and Lipid Profile and Some Trace Elements in Patients with Fatty Liver Disease in Thi-Qar Province, Iraq
No full textNon-alcoholic fatty liver disease (NAFLD) is an increasing worldwide health issue marked by fat buildup in more than 5% of liver cells. This disease is primarily caused by the obesity epidemic and affects approximately 25% of the world's population. NAFLD might lead to various degrees of cirrhosis in a persistent liver illness. Lastly, NAFLD could result in the development of cancer of the liver. This review aims to describe and estimate erythropoietin levels and lipid levels (TG, TC, HDL, LDL, V-LDL) and some trace elements (Selenium (Se), Iron(Fe)) in patients with fatty liver disease. Serum erythropoietin and lipid levels (triglycerides (TG), cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), very low-density lipoprotein (V-LDL)) and selenium and iron levels were determined in 96 volunteers from men and women: 73 patients and 23 healthy control group. Patients were diagnosed by an internist medicine specialist. Inclusion Criteria: The cases included in this study are patients with non-alcoholic fatty liver disease, diabetes, and hypertension. Exclusion Criteria: The cases excluded from this study are patients with alcoholic fatty liver disease or fatty liver with other diseases such as heart and kidney disease. An important increase in focus of erythropoietin in fatty liver in the DM also fatty liver in the DM and HTN cohorts compared to fatty liver and controls groups (p≤0.05), An important increase in focus of TC in patients cohorts compared in the controls groups (p≤0.05), An important increase in focus of TG and VLDL in patients groups compared to controls groups (p≤0.05), An important increase in focus of LDL in patients groups compared to controls groups (p≤0.05),and An important decrease in focus of HDL in patients groups compared to controls groups (p≤0.05). An important increase in focus of Se in patients groups compared to controls groups (p≤0.05). An important increase in focus of Fe in patients groups compared to controls groups (p≤0.05). The study indicated that there was an increase in the levels of erythropoietin, as well as an increase in the level of (TG, TC, LDL, V-LDL), Se, Fe, and a decrease in the level of (HDL) in patient’s fatty liver
A statistical study on diabetes
No full textDiabetes, sometimes referred to as diabetes mellitus (DM), is a collection of metabolic diseases characterized by persistently elevated blood sugar levels. If left untreated, symptoms may include increased thirst, increased appetite, and frequent urination. Many consequences, including acute diseases such diabetic ketoacidosis, hyperglycemia, hyperosmolar state, and even mortality, may result from diabetes. Serious ailments include heart disease, stroke, chronic renal disease, foot ulcers, nerve damage, vision damage, and cognitive decline are examples of long-term effects. We shall investigate the definition of diabetes, its many forms, its causes, its symptoms, and its preventative measures in this study
The Effectiveness of Foot Massage on Pulmonary Parameters among Patients with Acute Coronary Syndrome
No full textAcute coronary syndrome (ACS) is a significant health burden in the USA, affecting over a million patients each year. The fatal illness known as ACS is one of the main reasons people go to emergency rooms. Moreover, this disease is one of the leading causes of death worldwide with a 25% fatality rate. Unstable angina (UA), non-ST-segment-elevation myocardial infarction (NSTEMI), or ST-segment-elevation myocardial infarction (STEMI) are all grouped together under the term ACS. The aim of the present study is to determine the effectiveness of foot massage on pulmonary parameters among patients with acute coronary syndrome. A quasi-experimental study was conducted in Karbala center for cardiac diseases and surgery from December 25th 2023, to May 11th 2024. The sampling of a non-probability purposive contained 60 patients with severe coronary syndrome; the sampling separated into groups of intervention and control. At the group of intervention, the patients are instructed to performed four-step foot massage similarly 5 minutes for each foot. While at the group of control, the patients just take the treatment of routine medical. The pulmonary parameters were checked in the two groups before, after 5 min, and 10 min after the foot massage. The mechanism of study contained of two parts: the one part inclusive clinical data and the socio demographics of patient, and the part two was used to evaluate the pulmonary parameters by use the physiological parameters chick list. Statistical tests were conducted using the software SPSS for Microsoft Windows version 24, with a level of significance of 5% (p value < 0.05). That are a significant statistical differences between the mean of the pulmonary parameters readings for the study group while there is no significant statistical difference between the mean of the readings of the pulmonary parameters for the control group. The study found that the foot massage is effective for improving the respiratory rate and oxygen saturation (SPO2)
Evaluation of Mothers' Awareness and Perceptions about Vitamin D Deficiency among Young Children
No full textVitamin D deficiency is a major public health problem worldwide in all age groups. It is a common problem in pediatrics, especially those who have chronic illness, and malnourished, limited geographically to the amount of sun exposure, as well as those with darker skin. This study aim to assess mothers' awareness and perceptions towards vitamin D deficiency among young children. A cross-sectional study, descriptive design was conducted in AL-Najaf health/ primary health care centers October 2023 to February 2024. The findings of present study indicate that the majority of mothers' awareness about vitamin D was poor. Regarding to mothers perceptions was positive. There is a significant relationship between mother's awareness about vitamin D deficiency and their demographic data such as level of education, mother occupation and type of family at (p-value > 0.05), while there is a non- significant relationship with remaining demographic variables. Most of the study sample received information about the importance of vitamin D; the doctors is the main source of these information. The study recommended the need to emphasize the educational sessions provided to mothers about importance of vitamin D to increase their knowledge and interest