Central Asian Journal of Medical and Natural Science
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Study of Some Immunological Aspects of Diabetic Type1 Infected with Toxoplasmosis
No full textThe present investigation was conducted on type 1 diabetes individuals infected with the Toxoplasma gondii parasite. The potential association between toxoplasmosis infection and type 1 diabetes (1DM) remains under investigation. This study aims to examine the role of interleukin-2 and interleukin-17 in the immune response to parasites. A total of 160 serum samples were obtained from Thi-Qar hospitals and private laboratories, categorised into four groups: 40 samples from type 1 diabetes patients infected with toxoplasmosis, 40 samples from type 1 diabetic patients only, 40 samples from patients with toxoplasmosis only, and 40 samples from the control group. The study results indicated that the serum concentration of IL-2 was highest in the type 1 diabetes group infected with toxoplasmosis, followed by the type 1 diabetic group alone, then the toxoplasmosis-infected group, with the control group exhibiting the lowest concentration. The IL-17 serum levels were elevated in the toxoplasmosis-infected group, followed by the type 1 diabetes group infected with toxoplasmosis, while the control group had the lowest concentration
Evaluating Blood Transfusion Protocols and Practices in Obstetric Care A Study of Iraqi Hospitals.
No full textBlood transfusion is an essential part of patient care in obstetrics and gynaecology. Blood transfusion procedures need to be evaluated regularly to identify opportunities for improvement. The objective of this article is to evaluate the clinical outcomes of blood transfusion protocols and practices in the context of obstetric care in Iraqi hospitals.110 women who gave birth vaginally or caesarean over a six-month period were the subjects of a prospective study conducted at hospitals in Baghdad, Iraq. Obstetric patients during the peripartum phase and gynecological hospitalizations who had blood transfusions were included in the study's discussion of blood transfusion guidelines and practices for obstetric care. Records were kept on the patient's attributes, type of blood, pretransfusion packed cell volume (PCV), transfusion indication, blood product utilized, number of pints, and donor group. A total of 110 pregnant women who had blood transfusions were included in this study. Anemia and antepartum hemorrhage were the main reasons for transfusions in obstetrics patients. 70.91% of women with whole blood, while 29.09% with sedimented blood. Blood transfusion rates were comparatively high, with obstetric rates being higher. Blood transfusions were indicated mostly for hemorrhage in obstetrics and chronic anemia in gynecology
CHEMICAL STUDY OF THE PLANT ZIZIPHIUS RUGOSA BELONGING TO THE RHAMNACEAE FAMILY USING GASS CHROMATOGRAPHY MASS
No full text: The chemical study dealt with the chemical content of the studied leaves of the Sidr plant Ziziphius rugosa. The chemical compounds were identified using Gas Chromatography Mass Spectrometry (GC/MS) technology by comparing the chemical content. It was revealed that the studied sample contained the compound 3-Butyn-1-ol. The appearance of a repeat of the chemical compound was also recorded. 3-Butyn-1-ol six times in the leaves of the plant under study and with different curved areas and retention times for the same species using the GC-Mass device. Nine chemical compounds were detected accumulated in the leaves of the Sidr plant Ziziphius rugosa, with the highest area value being 18.79% at The peak is 15 with a holding time of 31.388 minutes for the active compound Squalene, while the lowest area is 1.55 at peak 8 with a holding time of 21.210 minutes for the compound Vaccenoylglycerol cis-1 (Figure 4-1), and the highest percentage appeared for the active compound 3-Butyn-1-ol with a value of 30.32% after collecting six different peaks (1,2,3,5,9,14
ANTIBIOTIC RESISTANCE PROFILES OF PSEUDOMONAS AERUGINOSA ISOLATED FROM CLINICAL SAMPLES
No full textPseudomonas aeruginosa is identified as an opportunistic pathogen since it predominantly creates nosocomial infections in immune compromised people; total of 20 samples of P. aeruginosa obtained from a variety of locations in Baghdad hospitals isolated from: burns, wounds and sputum collected from October 2021 to the April 2022, isolates cultured by Using culture conditions, biochemical assays, and the VITEK-2 compact system. For all bacterial isolates, the antibiotic sensitivity test is valid according to the minimum inhibitory concentration (MICs). The maximum level of resistance was demonstrated to be against Tigecycline (8), followed by Cefazolin (64), while high sensitive was to Ciprofloxacin (0.25), followed by Levofloxacin (0.5) and Gentamicin (1), cefepime (1), Ceftazidime (2) and Imipenem (2), Amikacin (2) and Piperacillin /Tazobactum (8) respectively according to MICs results of each antibiotics
КОНЦЕНТРИЧЕСКОЕ И ЭКСЦЕНТРИЧЕСКОЕ РЕМОДЕЛИРОВАНИЕ МИОКАРДА ПРИ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ
No full textСердечная недостаточность — это клинический синдром, который возникает, когда сердце не может обеспечить достаточный кровоток для удовлетворения метаболических потребностей или системного венозного возврата. Сердечная недостаточность классифицируется по фракции выброса левого желудочка (ФВЛЖ), а не по геометрии левого желудочка (ЛЖ) при этом рекомендованные в руководствах методы лечения сердечной недостаточности со сниженной фракцией выброса (СНСнФВ), но не сердечной недостаточности с сохраненной фракцией выброса (СНсФВ). Гипертрофия может протекать как по патологическому, так и по физиологическому типу. Оба типа можно разделить на эксцентрические и концентрические. У большинства пациентов с СНСнФВ имеется эксцентрическая гипертрофия ЛЖ, но у некоторых наблюдается концентрическая гипертрофия ЛЖ. Понимание физиологического ремоделирования сердца может обеспечить стратегию улучшения функции желудочков при сердечной дисфункции
KNOWLEDGE OF COMMUNITY ON BABESIOSIS IN KIRKUK PROVINCE-IRAQ
No full textBackground: Babesia is an intra-erythrocytic protozoan parasite found inside the red blood cells, transmitted by Ixodid ticks, in which sexual cycle occurs. It causes babesiosis in animals and human.
Objective: The object of present study was to determine the knowledge, regarding babesiosis mong different groups of population at Kirkuk province- Iraq.
Methods: A cross-sectional survey was conducted during period from July –November 2022, in Kirkuk-Iraq. A questionnaire was formulated which included demographic data of the respondents and their knowledge toward babesiosis
Results: Regarding the knowledge of studied groups on the causative agent, the vast majority of participants knew the cause of the disease was parasite (63.5%), mode of transmission is by ticks (40.2%) and seasonal distribution in summer (53.3%). Concerning the prevention and control, the highest rate of participant (58.9%) did not comment on prevention and control of babesiosis and (15.0%) of participants knew that vector control is a correct way of prevention and control
РАСПРОСТРАНЕНИЕ КОРОНАВИРУСНОЙ ИНФЕКЦИИ ПО ВСЕМУ МИРУ
No full text30 января 2020 года Всемирная Организация Здравоохранения (ВОЗ) признала вспышку коронавирусной инфекции в Китае чрезвычайной ситуацией в области общественного здравоохранения, имеющую международное значение. Генеральный директор ВОЗ Тедрос Адханом Гебрейесус после совещания чрезвычайного комитета в Женеве заявил «Я объявляю международную чрезвычайную ситуацию в области общественного здравоохранения из-за глобальной вспышки коронавируса». В статье представлены текущие эпидемиологические показатели COVID-19 для территории Приморского края. Определены уровни заболеваемости и пораженности COVID-19 в ПК, РФ за период с 14 апреля 2020 по 14 мая 2020. Описаны этиология и патогенез коронавирусной инфекции. Отмечены клинические проявления и факторы риска данной инфекции. Проведен обзор литературы о сложившейся ситуации в мире
Morphological Features Cardiac Muscles in Hyperparathyroidism
No full textThe goal of this research is to determine how variations in parathyroid gland functional activity affect the morphological intensity of the heart muscles. The dynamics of the genesis of cardiac muscles is disclosed, and changes in the structure and morphology of the heart's major vessels are researched, thanks to the findings of morphological research methods. The study's findings revealed a distinction between the hyperparathyroid patient's normal histological appearance of the heart's major arteries
Clinical Evaluation of the Results of Organ-Preserving Operations in Liver Echinococcosis with Elastic Fibrous Capsule
No full textOne of the urgent issues in the surgery of echinococcosis of the liver remains the option of treatment of the residual cavity, implying both antiparasitic efficacy and the possibility of accelerating the processes of obliteration of the fibrous capsule. The article highlights the results of echinococcectomy from the liver, analyzed taking into account the method of treatment of residual cavities with an elastic fibrous capsule. The proposed method for treating the residual cavity in uncomplicated forms of liver echinococcosis in the presence of an elastic fibrous capsule that subsides after extraction of the parasite, includes laser radiation, which makes it possible to treat cavities of any configuration, inhibition of the growth of pathogenic flora, as well as in combination with the use of a powdered composition "HEMOBEN". The technique promotes local hemo and lymphostasis, sealing of the bile duct microspheres and strengthening of the processes of obliteration of the walls of the fibrous capsule both during suturing and vacuum drainage. The method can be used as an alternative to pericystectomy and liver resection
Immunological Study of Unexplained Recurrent Spontaneous Abortion
No full textMiscarriage poses a significant health concern, with a substantial proportion attributed to immunological factors, particularly maternal immune responses towards the fetus. This study aimed to identify immunological biomarkers associated with unexplained recurrent abortions. Vaginal swabs and blood samples were collected from 100 women with recurrent abortions and 80 control women with previous normal pregnancies. Analysis revealed significantly higher T-helper 1 cytokine levels and lower T-helper 2 cytokine levels in women with recurrent abortions compared to controls. The imbalance in T-helper cell responses, indicated by elevated Th1:Th2 ratios and IFN-γ:IL-4 and IFN-γ:IL-10 ratios, suggests a potential mechanism underlying pregnancy loss. These findings underscore the importance of immune modulation in pregnancy outcomes and highlight the need for further research to elucidate underlying mechanisms and develop targeted interventions for optimizing maternal-fetal tolerance