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Disparities in Complication Rates Among Ethnic Minorities Undergoing Bariatric Surgery in the UK.
No full textBackground: Ethnicity may play a significant role in determining surgical outcomes. This study examines the disease profiles across ethnic groups and investigates whether ethnicity influences the risk of complications following bariatric surgery.
Methods: Data from the United Kingdom's National Bariatric Surgery Registry (NBSR) were analysed, encompassing all adult patients undergoing bariatric procedures. Comparative analyses were performed, and a multivariable regression model was developed to identify factors associated with postoperative complications.
Results: A total of 77,710 (78.8% female) patients were included in the analysis, with a median age of 46 (IQR 37-55) years. Most patients were Caucasian (91.6%), followed by Asian (4.1%), Afro-Caribbean (2.5%), and African (1.7%) groups. Afro-Caribbean patients had the highest median BMI (44.5 kg/m2) and the highest prevalence of hypertension (43.2%), while Asian patients were younger (median age 41 years) and had a higher prevalence of diabetes mellitus (29.1%). African and Afro-Caribbean patients were less likely to self-fund their procedures (14.9% and 10.6%, respectively) compared to Caucasians (25.9%). Complication rates were the highest among Afro-Caribbean patients (5.8 vs 4.8%, p < 0.001) compared to Caucasians. Multivariable regression analysis identified ethnicity as an independent predictor of postoperative complications, with Afro-Caribbean (OR 1.47, 95% CI 1.22-1.87, p < 0.001) and African (OR 1.34, 95% CI 1.05-1.70, p = 0.019) patients demonstrating significantly increased risks.
Conclusions: This registry analysis identified ethnic disparities in disease profiles and postoperative outcomes among bariatric surgery patients in the UK, underscoring the need for targeted health policies to improve outcomes in these vulnerable populations
Quantitative precision in cardiac sarcoidosis imaging: the emerging role of myocardial-to-background ratio in FDG-PET.
No full text© 2025 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd.4.0/)
Hybrid Closed-Loop Therapy in Adults with Type 1 Diabetes in England: Long-Term Outcomes from a Real-World Observational Study.
No full textÓ The Author(s) 2025. Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the CreativeCommons License [CC-BY] (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, andreproduction in any medium, provided the original work is properly cited.820DIABETES TECHNOLOGY & THERAPEUTICSVolume 27, Number 10, 2025Mary Ann Liebert, Inc.DOI: 10.1089/dia.2025.0165To evaluate longitudinal real-world outcomes in adults with type 1 diabetes initiating hybrid closed loop (HCL). Adults with type 1 diabetes, managed with an insulin pump and intermittently scanned continuous glucose monitoring with hemoglobin A1c (HbA1c) ≥8.5% (69 mmol/mol), were started on HCL between August and December 2021 as part of the National Health Service England HCL pilot. We collected outcomes, including change in HbA1c, sensor glucometrics, Gold score (hypoglycemia awareness), diabetes distress score, acute event rates, and user opinion of HCL. In total, 420 HCL users across 30 diabetes centers in the United Kingdom were included (median age 40 [interquartile range or IQR 29-50] years, 68% female, 85% White British). Over a median follow-up of 12 months (IQR 8-28) (range 6-38 months), mean adjusted HbA1c reduced by 1.4% (95% confidence interval [CI] -1.5, -1.3; < 0.001) (16 mmol/mol [95% CI -17, -14]; < 0.001). Time in range (70-180mg/dL) increased from 33.7% to 60.4% ( < 0.001). The proportion of individuals achieving HbA1c ≤7.5% (58 mmol/mol) increased from 0% to 33.1% ( < 0.001). Diabetes distress score reduced (-1.1; 95% CI -1.3, -1.0; < 0.001) and Gold score reduced (-0.4; 95% CI -0.5, -0.2; < 0.001). The percentage of individuals with impaired hypoglycemia awareness (Gold score ≥4) decreased (16.6% [baseline] vs. 9.2% [follow-up]; < 0.001). Almost all participants stated that HCL had a positive impact on quality of life (94.5%; 361/382). The number of hospital admissions was low. Long-term real-world use of HCL is associated with sustained improvements in glycemic and person-reported outcomes in adults with type 1 diabetes and above-target HbA1c levels.The Association of British Clinical Diabetologists fundedthe development of the secure anonymized online tool andclinical research fellow time to undertake the analysis. NHSEngland funded the provision of HCL systems as part of areal-world pilot scheme launched in 2021. S.H. is supportedby the Medical Research Council Clinical AcademicPartnership award (MR/W030004/1)
Sleep and wider determinants of health (evidence summary)
No full textThis is an evidence summary produced by the Somerset NHS Foundation Trust Knowledge and Library Service
Disclaimer: We will endeavour to use the best, most appropriate and most recent sources available to ensure that the information supplied is accurate, up-to-date and evidence-based. It is the responsibility of the requestor to determine the accuracy, validity and interpretation of the search results. No responsibility can be taken by the library for any action taken on the basis of this information. New evidence may have been published since the date this evidence summary was created
Six early CPAP-usage behavioural patterns determine peak CPAP adherence and permit tailored intervention, in patients with obstructive sleep apnoea.
No full text© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.Background: High rates of non-adherence to continuous positive airway pressure (CPAP) in obstructive sleep apnoea hamper good clinical outcomes. Current recommendations assumes two behaviours (adherence and non-adherence) and days 7-90 follow-up post-CPAP initiation mitigates against non-adherence.
Objectives: To investigate associations between early CPAP-usage behaviours and (1) CPAP adherence at month 3 of treatment and (2) sleep centres' treatment pathways (the procedures patients undergo that may affect barriers or facilitators of CPAP adherence).
Methods: We conducted growth mixture modelling (GMM) on retrospective data from 1000 patients at 5 UK sleep centres. Night 1 to month 3 telemonitored CPAP-usage data were downloaded from 200 patients per centre who started CPAP in 2019 (100) or 2020 (100). Adherence was defined using accepted criteria (mean CPAP-usage ≥4 hours/night for ≥70% of nights).
Results: GMM identified six distinct CPAP-usage behaviour patterns over month 1. In four (54% of patients), CPAP-usage increased or decreased, in two (remaining 46%), CPAP-usage/non-usage was consistent. 62% of the cohort were non-adherent by month 3, despite pathways following current recommendations. 98% of patients who were non-adherent by month 3 were already non-adherent by month 1. Regression analysis with a separate dataset demonstrated that early CPAP-usage behaviour explained 86% of the variance in CPAP non-adherence at month 3.
Conclusions: These data, supported by previous work, indicate that recommended day 30-90 follow-up is too late to prevent CPAP non-adherence. Determining CPAP-usage behavioural pattern in week 2 identifies risk of CPAP non-adherence at month 3 and permits the possibility of tailored interventions
Provision of secondary prevention medication information to stroke patients with aphasia: an audit proposal
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Accessibility challenges for deaf and blind people using remote interpreting services to access healthcare (evidence summary)
No full textThis is an evidence summary produced by the Somerset NHS Foundation Trust Knowledge and Library Service
Disclaimer: We will endeavour to use the best, most appropriate and most recent sources available to ensure that the information supplied is accurate, up-to-date and evidence-based. It is the responsibility of the requestor to determine the accuracy, validity and interpretation of the search results. No responsibility can be taken by the library for any action taken on the basis of this information. New evidence may have been published since the date this evidence summary was created
SFT KLS newsletter - November 2025
No full textThe November edition of the Knowledge and Library Service newsletter, from Somerset NHS Foundation Trust
Redesigning ward accreditation (evidence summary)
No full textThis is an evidence summary produced by the Somerset NHS Foundation Trust Knowledge and Library Service
Disclaimer: We will endeavour to use the best, most appropriate and most recent sources available to ensure that the information supplied is accurate, up-to-date and evidence-based. It is the responsibility of the requestor to determine the accuracy, validity and interpretation of the search results. No responsibility can be taken by the library for any action taken on the basis of this information. New evidence may have been published since the date this evidence summary was created
A clinical audit of women’s records of care providing warm compresses in the second stage of labour.
Full text linkThis work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
General rights
All content in PEARL is protected by copyright law. Author manuscripts are made available in accordance with publisher
policies. Please cite only the published version using the details provided on the item record or document. In the absence of an
open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author