Journal of Medical Genetics and Clinical Biology
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MIDWIFERY CARE CONTINUITY OF CARE (COC) MRS. B, 39 YEARS OLD, G4 P2012, 37/38 WEEKS OF GESTATION + IUFD NOTOPURO REGIONAL GENERAL HOSPITAL, SIDOARJO
Get PDFObjective: This study aims to analyze the implementation of Continuity of Care (COC) midwifery care for Mrs. B, a 39-year-old woman (G4 P2012) at 37/38 weeks of gestation with Intrauterine Fetal Death (IUFD) at Notopuro Regional General Hospital, Sidoarjo. The study emphasizes holistic care addressing physical, psychological, social, and spiritual needs. Method: A descriptive case study approach was employed to provide an in-depth analysis of Mrs. B's condition. Data were collected through interviews, direct observations, and medical record reviews. The focus of care included pregnancy management, delivery, postpartum care, and psychosocial support. Results: The COC approach effectively facilitated comprehensive care for Mrs. B, integrating medical management of IUFD and psychosocial support to address emotional distress due to fetal loss and abandonment by her spouse. This care model promoted physical recovery and emotional resilience, contributing to Mrs. B's readiness for future reproductive health planning. Novelty: This study highlights the critical role of COC in managing IUFD cases by integrating continuous, patient-centered care that extends beyond physical treatment to encompass psychosocial recovery. The findings underscore the importance of personalized support systems for high-risk pregnancies to improve maternal health outcomes holistically
CLINICAL COURSE OF ALCOHOLIC POLYNEUROPATHY AND ALCOHOLIC MYOPATHY OBSERVED IN ALCOHOLISM
Get PDFObjective: This article aims to explore the most prevalent neurological manifestations associated with alcoholism, including dysmetabolic encephalopathy, central pontine myelinolysis, demyelination of the corpus callosum, alcoholic polyneuropathy, and alcoholic myopathy. Methods: The study examines the potential therapeutic role of drugs containing succinate, focusing on their application in pathogenetic treatment approaches to address these neurological conditions. Results: Key findings indicate that succinate-containing drugs may offer significant benefits in mitigating the pathological effects of alcoholism on the nervous system by targeting specific mechanisms underlying these disorders. Novelty: The article provides novel insights into the therapeutic potential of succinate-based treatments, presenting an alternative strategy for addressing complex neurological disorders linked to chronic alcohol consumption
DIAGNOSTIC EXAMINATION AND APPROACHES IN ADOLESCENTS WITH A HIGH RISK OF ALCOHOLISM
Get PDFObjective: The aim of this study is to explore the efforts of public health professionals, including scientists, narcologist-practitioners, and teachers, in addressing the issues of alcoholism and drug addiction. This includes promoting medical and legal knowledge, as well as providing preventive and therapeutic measures. Methods: The study investigates the methods employed in the prevention of alcoholism and drug addiction, including public lectures, visual propaganda (posters, booklets, etc.), and media campaigns. It also explores the role of a specialized drug service that offers medical-preventive, medical-social, and medico-legal support to individuals affected by addiction. Results: The findings reveal that these methods contribute to raising awareness about addiction and its consequences. The media, both traditional and digital, plays a significant role in reaching a broader audience, while the drug service provides essential assistance in managing and treating addiction cases. Novelty: This study highlights the integrated approach involving education, public campaigns, and specialized medical services in addressing the complex issue of addiction. It emphasizes the importance of both preventive and therapeutic interventions in tackling alcoholism and drug dependency
IMPLANTATION AND RESTORATION OF TEETH: ERRORS AND COMPLICATIONS AFTER IMPLANTATION
Get PDFObjective: This study is to evaluate the body’s response to temperature changes following dental implant surgery, specifically focusing on the natural increase in temperature post-surgery. Methods: Used involve observing patients after implant insertion, where a small incision is made in the gum to access the bone, and the implant is screwed into the jaw. This process disrupts bone tissue integrity, leading to a temporary rise in body temperature. Results: The results indicate that a temperature increase up to 38 degrees Celsius is normal within the first 2-3 days after surgery due to the body's natural response to microsurgical interventions in the oral cavity. Notably, implants are made from hypoallergenic materials, thus preventing allergic reactions. Novelty: Its exploration of the diverse patient responses to temperature changes, emphasizing that individual tolerance varies, with some patients feeling unwell even at 37 degrees Celsius. For managing elevated temperatures, the use of antipyretic drugs like Paracetamol or Ibuprofen is recommended. This research contributes to understanding postoperative reactions and patient care in dental implant procedures
DETECTION OF OQXAB EFFLUX PUMPS GENE IN ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIA ISOLATED FROM PREGNANT WOMEN SUFFERED FROM URINARY TRACT INFECTIONS AND DIABETES MELLITUS IN BASRAH
Get PDFConsiderably, pregnant women with diabetes mellitus are highly susceptible to urinary tract infections. The aim of the study is investigate the incidence of OqxAB efflux pumps gene among Escherichia coli and Klebsiella pneumonia isolates from urine of pregnant women suffered from urinary tract infections and Diabetes mellitus. E.coli and K.pneumonia were identified using conventional methods and confirmed by specific 16S rDNA primers. Antibiotic susceptibility test of E. coli and K. pneumonia isolates against several antibiotics were examined using Vitek®-2 compact system .The production of efflux pump by E. coli and K. pneumonia isolates were investigated phenotypically using ethidium bromide-agar cartwheel method (EtBr CW). Moreover, OqxAB Efflux Pumps genes were tested. The results showed that among 100 urine samples, 40 urine samples showed positive bacterial growth where 21(51%) E coli isolates, 8(20%) K. pneumonia isolates. In terms of antibiotic sensitivity, all E.coli and K.pneumonia isolates were resistant to ampicillin, piperacillin and ticarcillin, respectively. The prevalence of OqxAB efflux pump genes frequency ranges from 72% in E. coli and 50% in K. pneumonia
CONSEQUENCES OF LEADING HEALTH LIFESTYLE ON LIPID PROFILE
Get PDFThe activity of improving and promoting health is through leading proper health behavior which includes perfect and suitable methods for health living; through leading health lifestyle; via periodic medical consultations and attending physicians for medical checkup and advice. Beside choosing balanced diet and encourage sport exercises; cessation of smoking and alcohol intake. The other aspect, that results in promoting health, longevity and quality of living through preventing of disease occurrence should be through clinical and physical examination via screening services of diseases, such as ischemic heart disease, hypertension and renal problems. All these personal activities will lead to health lifestyle, which consequently is going to minimize the diseases might occur. On conclusion, the study shows that these behavioral aspects will reduce lipid profile; blood pressure, body weight and increase physical fitness in 42% of cases and border line effect on outcome is approximately about 58% of cases and the variable that plays a role is socio – economic statu
STUDY OF THE PREVALENCE OF INTESTINAL PARASITIC INFECTIONS AMONG CHILDREN IN SHATRAH DISTRICT / THI-QAR PROVINCE - SOUTH OF IRAQ
Get PDFThe current study aimed to determine the prevalence of intestinal parasites among children from newborns to ten years of age in different areas affiliated with the Shatra district in Dhi Qar Governorate in southern Iraq, as these areas suffer from poor health and living services in addition to a lack of awareness and interest in personal and health hygiene. The study was designed by taking 100 A random sample from different areas. The results were 25% of healthy children, while 75% were infected. The widespread infections were with the parasites Giardia lamblia and Entamoeba histolytica.
The results confirmed that most of the infected children were between two and four years of age, in addition to the fact that the most common infections were the combined infections of the Entamoeba parasite and Giardia for the same infected people, with a very high rate of up to 56%, while the infection of children with the Entamoeba parasite alone was 18.7% and Giardia alone was 25.3% in addition. The percentage of females is 65% while the percentage of males is 35% in parasitic infections and The infection rate in the countryside was higher than the infection rate in cities, as the infection rate in the countryside was (55%) and in the cities (45%)
BODY MASS INDEX AND COMPLIANCE IN PATIENTS WITH CORONARY HEART DISEASE COMORBID WITH DIABETES MELLITUS
Get PDFObjective: to evaluate the relationship between body mass index and compliance in patients with coronary artery disease comorbid with diabetes mellitus.
Material and methods: 148 patients with stable angina pectoris (hereinafter referred to as: stable angina - SA) and type 2 diabetes mellitus (DM), i.e. with IHD+DM. Median age = 60.9±8.5 years. According to the blood glucose level, 3 groups were divided: group 1 – 74 patients whose blood glucose level was ≤ 10.0 mmol/l; Group 2 – 43 patients whose blood glucose level was = 10.1-15.0 mmol/l; Group 3 – 31 patients whose blood glucose levels were ≥ 15.1 mmol/l. Of the entire sample of patients, in 99 (66.9%) cases the body mass index was calculated - BMI, kg/m2 (n=99). The median BMI was 29.0±3.6 kg/m2. Compliance was assessed using the Morisky-Green questionnaire.
Results: In patients with coronary artery disease + diabetes, an increase in blood glucose levels ≥ 15.1 mmol/l was associated with a trend towards obesity, which was confirmed by an increase in both the number of patients with obesity and the increase in the degree of obesity in them (p<0.05).
In patients with high blood glucose levels, in terms of calculating BMI, there was a more pronounced tendency to obesity and low adherence to drug therapy, while, according to CAG data, the frequency of lesions of the circumflex artery was more than 4.5 times more prevalent, in comparison with lesions of the LAD and RCA.
Conclusion: Given the increased risk of diabetes complications in obese patients, clinicians must understand how to treat obesity in patients with diabetes, including adherence to drug therapy, as well as prevention of its complication
PREVALENCE OF BACTERIAL VAGINITIS AMONG WOMEN USING DIFFERENT TYPES OF IUDS
Get PDFBackground: A coil, also known as an intrauterine contraceptive device (IUCD or ICD), is a small birth control method that is put into the uterus to stop pregnancy. It usually starts in the endocervix and vagina and spreads up the body, causing endometritis, salpingitis, tubo-ovarian abscesses, parametritis, oophoritis, and/or pelvic peritonitis.
objective: The objective of the current study was to investigate the prevalence of bacteria causing vaginitis among women using different types of intra uterine devices
Materials and methods: The study was conducted in Kirkuk city from November 1, 2023, to April 30, 2024, using high vaginal swabs from 186 fertile women using intrauterine devices (IUDs). Demographic, medical, and gynecologic histories were recorded, and all patients underwent pelvic examinations. Swabs from the posterior fornix of the vagina were taken for microbiological analysis. The study included women aged 18-45 using IUDs, and excluded those who had received antibiotics, had preexisting systemic or infectious diseases, or experienced bleeding. Ethical approval was obtained, and informed consent was signed by all participants. The swabs were cultured on blood agar , MacConkey agar, Mannitol salt agar and deman rosa sharpe agar and Eosin methylene blue agar and incubated at 37°C for 24 hours. The colonies were picked, purified, and identified through a series of biochemical tests, including Gram staining, motility tests, and enzyme and fermentation tests. The Vitek 2 system was used for microbial identification and susceptibility testing.
Results: In a study of 148 women using copper IUDs, 66 (44.59%) tested positive for vaginal swab cultures, while 82 (55.41%) tested negative. Similarly, among 38 women using hormonal IUDs, 17 (44.74%) had positive culture results, and 21 (55.26%) tested negative. Overall, out of 186 women tested, 83 (44.62%) had positive cultures. Among the 83 positive cases, 66 (79.52%) were in copper IUD users, and 17 (20.48%) were in hormonal IUD users. Escherichia coli was the most common bacterium, found in 40.91% of positive cultures, followed by Staphylococcus epidermidis (13.64%), and other bacteria including Staphylococcus aureus, Actinomyces israelii, and Proteus mirabilis, each at 9.09%. In women with positive cultures using copper IUDs, E. coli was most prevalent (47.06%), followed by Staphylococcus aureus and Staphylococcus epidermidis (17.65% each). Among women with positive cultures, 13.25% had diabetes, compared to 4.85% with negative cultures. Hypertension was present in 3.61% of women with positive cultures versus 1.94% with negative cultures. Duration of IUD use also showed a significant correlation with culture results. Women with positive cultures using copper IUDs had the highest percentage in the 1-2 year duration category (43.94%), while those using hormonal IUDs had the highest in the same category (47.06%). Antibiotic sensitivity testing revealed that Imipenem, Meropenem, Tigecycline, and Colistin were 100% effective against E. coli isolates from women using IUDs. However, high resistance rates were observed for Ampicillin/Sulbactam (71.79%) and Ciprofloxacin (84.62%). Ceftolozane/Tazobactam and Gentamicin had relatively high sensitivity rates, while Ceftazidime/Avibactam showed moderate sensitivity.
Conclusions
The study reveals a significant proportion of women with copper and hormonal IUDs tested positive for vaginal infections, with Escherichia coli being the predominant bacterium isolated,significant differences were noted in the clinical presentation and comorbidities of women with positive cultures compared to those with negative cultures.study identified antibiotics with high sensitivity rates against E. coli isolates, such as Imipenem, Meropenem, Tigecycline, and Colistin, highlighting potential treatment options for IUD-associated infections caused by multidrug-resistant strains. Conversely, antibiotics like Ampicillin/Sulbactam and Ciprofloxacin demonstrated high resistance rate
DISEASES THAT ARE DIAGNOSED AND TREATED BY X-RAYS AND GAMMA RAYS
Get PDFrays have long been one of the most effective tools in detecting and diagnosing diseases because of their effective and practical properties in diagnosing the various diseases that appear in the x-ray image. Diagnostic x- rays are considered an examination carried out using To see the internal anatomy of the body Accurately and pinpoint the tiny spots. The x-ray beam passes through the body, and is absorbed in different quantities, depending on the absorption capacity of the material. Dense materials such as bones and metal appear in white in the x-ray image, while air in the lungs appears in black, and muscles and fat appear in shades of grey. In some tests, we resort to introducing contrast dyes such as iodine or barium into the body to provide more details of the part to be imaged, such as imaging the bile ducts, spinal cord (myelography), urinary tract, and other parts that need the use of contrast dyes. in These methods enabled us to diagnose various diseases such as chest diseases and various cancers If a foreign body is detected or calcium calcifications are seen