47325 research outputs found
Sort by
Leucine catabolism is associated with longevity in female eastern lubber grasshoppers
Background & Aims: Dietary isoleucine restriction can improve metabolic health and increase lifespan. It has been hypothesized that shifts in branched-chain amino acid catabolism drives this longevity effect. Impaired branched-chain amino acid catabolism is linked to several age-related diseases. We investigated whether dietary isoleucine restriction increases leucine catabolism and associates with longevity and full reproduction.
Methods: In two experiments, adult female Eastern Lubber grasshoppers (Romalea microptera) were assigned to either a high-quality diet (Balanced ile), or diets with varying isoleucine content (Moderate ile-R and Severe ile-R). In Experiment 1, we used a low-energy (Low Lettuce) group as a positive control for catabolism. In Experiment 2, we used an ad libitum lettuce (Ad Lib Lett) control to show the reproduction versus longevity trade-off.
Results: The Bal ile, Mod ile-R, and Sev ile-R diets all extended lifespan and increased leucine catabolism relative to the Ad Lib Lett group. The Sev ile-R and Low Lett groups showed the highest leucine catabolism but reduced reproduction. The Bal ile and Mod ile-R groups showed intermediate leucine catabolism—higher than Ad Lib Lett; lower than Low Lett—while sustaining reproduction similar to the Ad Lib Lett group. Valine catabolism showed similar patterns without consistent significant differences across groups. We observed no compensatory feeding on low isoleucine diets. However, isoleucine catabolism in the Mod ile-R and Sev ile-R groups did not exceed that of the Low Lett group, suggesting that the increased leucine and valine catabolism was driven by diet composition rather than energy deficit.
Conclusion: Weak leucine catabolism is linked to a short lifespan, while excessive catabolism is linked to impaired reproduction. Intermediate levels of leucine catabolism were associated with longevity and sustained reproduction
Marking Their Sacrifice: Headstones and History for USCT Veterans in Jacksonville, Florida
This research project investigated the unmarked graves of United States Colored Troops (USCT) veterans buried in Jacksonville, Florida. Despite their critical role in securing Union victory and advancing Black freedom during the Civil War, these soldiers were often denied pensions and formal recognition, including headstones. In collaboration with the University of North Florida and the Local Initiatives Support Corporation, the project involved archival research, military record verification, and cemetery documentation to confirm the service and burial sites of sixteen USCT veterans. Using resources such as Fold3, Works Progress Administration (WPA) grave registries, and institutional archives, the project resulted in the approval of federal headstone applications by the Department of Veterans Affairs. This work represents a significant step toward honoring these soldiers’ legacies. It contributes to restorative justice and public memory by reclaiming marginalized histories and ensuring that Black Civil War veterans are remembered with dignity
Clara White Mission Solicitation Coin Folder
Folder: Please Help Clara White Mission Pay for Building This Home coin gleaner. Undated
SOS Emergency Cash and Pledge Card for Donations, The Clara White Mission
Document: Solicitation for donation to the Elevator Fund, Clara White Mission, Jacksonville, Florida. Undated
Gym -Omar Rodriguez [Neg #20]
Roll of B+W Film scanned; Images of UNF Arena Construction; Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/2004/thumbnail.jp
UNF Men\u27s Tennis Trevarthan [Neg# 18]
Roll of B+W Film scanned, UNF Men\u27s Tennis Trevarthan, Unidentified tennis player, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1471/thumbnail.jp
UNF Men\u27s Tennis (Champs) [Neg# 6]
Roll of B+W Film scanned, UNF Men\u27s Tennis (Champs), Unidentified tennis player, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1499/thumbnail.jp
UNF VS JU_ Men\u27s Tennis [Neg# 10]
Roll of B+W Film scanned, UNF VS JU_ Men\u27s Tennis, Unidentified tennis players, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1527/thumbnail.jp
UNF VS JU_ Men\u27s Tennis [Neg# 6]
Roll of B+W Film scanned, UNF VS JU_ Men\u27s Tennis, Unidentified tennis players, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1523/thumbnail.jp
UNF Women\u27s Tennis Trevarthan [Neg# 9A]
Roll of B+W Film scanned, UNF Women\u27s Tennis Trevarthan, Unidentified tennis player, Date: Undatedhttps://digitalcommons.unf.edu/spinnaker-images/1537/thumbnail.jp