47325 research outputs found
Sort by
A pseudo-value regression approach for differential network analysis of co-expression data
No full textBACKGROUND: The differential network (DN) analysis identifies changes in measures of association among genes under two or more experimental conditions. In this article, we introduce a pseudo-value regression approach for network analysis (PRANA). This is a novel method of differential network analysis that also adjusts for additional clinical covariates. We start from mutual information criteria, followed by pseudo-value calculations, which are then entered into a robust regression model. RESULTS: This article assesses the model performances of PRANA in a multivariable setting, followed by a comparison to dnapath and DINGO in both univariable and multivariable settings through variety of simulations. Performance in terms of precision, recall, and F1 score of differentially connected (DC) genes is assessed. By and large, PRANA outperformed dnapath and DINGO, neither of which is equipped to adjust for available covariates such as patient-age. Lastly, we employ PRANA in a real data application from the Gene Expression Omnibus database to identify DC genes that are associated with chronic obstructive pulmonary disease to demonstrate its utility. CONCLUSION: To the best of our knowledge, this is the first attempt of utilizing a regression modeling for DN analysis by collective gene expression levels between two or more groups with the inclusion of additional clinical covariates. By and large, adjusting for available covariates improves accuracy of a DN analysis
LGBTQ+ Substance Use and Sexual Health and Wellbeing: A Special Commentary
Get PDFAlthough there has been some increased visibility in professional counseling literature pertaining to LGBTQ+ issues, gaps still exist. One such omission is how LGBTQ+ sexual wellbeing is negatively influenced by substance use. This commentary briefly reviews ways LGBTQ+ sexual wellbeing is negatively impacted by substance use. We provide commentary on how counselors may bolster sexual wellbeing when working with LGBTQ+ substance users and highlight gaps in counseling research. Lastly, recommendations for integrating this content into counselor training are provided
Ruth Green
No full textPhotograph: Portrait of Ruth Green, given as infant to Miss White, later raised by Mrs. Modania Chandley. (Postcard) Handwritten on reverse: Modania Chandley died 24 Nov 1915. Ruth Green died Oct 5 - 16 buried Oct 6 - 16 in Duval Cemetery given to E.M.M. White when an infant. Father Ben Green Mother Lizzie [illegible] Green care for by Modenia Chandley . Undated.https://digitalcommons.unf.edu/eartha_images/1081/thumbnail.jp
Unidentified People, War Bonds Drive
No full textPhotograph: Group drive for War Bonds. Undated.https://digitalcommons.unf.edu/eartha_images/1093/thumbnail.jp
Vacation Bible School Group Photograph
No full textPhotograph: Daily vacation Bible school at Bethel Baptist Church, June 21, 19--?https://digitalcommons.unf.edu/eartha_images/1137/thumbnail.jp
Bethel Baptist Church
No full textPostcard: Image of Bethel Baptist Institutional Church, Jacksonville, Fla. Undated.https://digitalcommons.unf.edu/eartha_images/1168/thumbnail.jp
Book Review: Learning in Action: Designing Successful Graduate Student Work Experiences in Academic Libraries.
No full textLearning in Action: Designing Successful Graduate Student Work Experiences in Academic Libraries, edited by Arianne Hartsell-Gundy, Kim Duckett, and Sarah Morris, describes a wide range of case studies and learning experiences dedicated to graduate student employment at academic libraries across the United States and Canada. A broad range of institutions are represented, from R1 to smaller schools, as well as universities with and without an LIS program
Photograph: Group Portrait, Church of Christ Birmingham
No full textImage of four rows of men, women and children standing and sitting in a church. Men in the center holding a sign. Sign: BRO. J.L. ASHURST CHURCH OF CHRIST AUG. 29.48. BHAM ALA. Date: 8/29/1948. One of 156 black and white photographs by R. Lee Thomas, an African American photographer active in the early twentieth century in the southern United States. Thomas’ work provides photographic documentation of southern black social life, primarily religious and labor groups, circa 1946-1949. The majority of the photographs depict groups from Birmingham, Alabama, and adjacent areas. His imprint contains the caption: Made by R. Lee Thomas, Mound Bayou, Mississippi, The Oldest Negro Town in America.https://digitalcommons.unf.edu/rthomas/1177/thumbnail.jp
Willie Weaver\u27s Big Apple Swingtime Review
No full textPhotograph: Willie Weaver\u27s Big Apple Swingtime Review. Undated. Oversize photograph.https://digitalcommons.unf.edu/eartha_images/1237/thumbnail.jp