Istanbul Technical University
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Dynamics of Plateau Growth: Geodynamic Modeling of the East AnatolianPlateau Uplift Through Double Subduction Processes
No full textThe Turkish–Iranian Plateau was formed by the collision between the Arabian andEurasian plates, commencing along the Bitlis-Zagros suture in the Late Eocene (~30-35 Ma). This region, commonly partitioned into the East Anatolian Plateau and theIranian Plateau, is associated with significant differences in terms of lithosphericstructure despite an overall average of ~2 km. The geodynamic evolution of EastAnatolia is represented by a double subduction system, where the two branches ofNeo-Tethys were subducting beneath Eurasia, constantly accumulating accretionarymaterial that forms the bulk of the plateau today (i.e., East Anatolian AccretionaryComplex). Seismic evidence demonstrates that the region has unusually thin MOHO(~35 km around Lake Van region) while the whole area is formed mostly by oceanic(accretionary) material and is underlain by no or very thin mantle lithosphere. Theuplift of East Anatolia is attributed to slab break-off and slab peelback (delamination),combined with crustal shortening. However, the intricate plate dynamics arising fromsuch a double subduction system, controlling plateau formation remains unclear.Here, we conducted 2D numerical experiments and comparative model sets indicatethat, in a double subduction system like Eastern Anatolia, the mechanisms of slabbreak-off and peelback heavily depend on the rheology of the subducting plates andthe coupling between the overlying and subducting plate along the trenches. In casesof strong coupling between subducting and overlying plates, we observed anamalgamation of the two subducting plates as they converge, potentially resulting ina break-off as a single blob, depending on plate rheology. Conversely, in models withweaker coupling along the trenches, peelback along the northern slab creates a thinlithosphere along the accretionary prism, such as in the evolution of the EasternAnatolian Plateau. Our results highlight the important interaction between thesubduction systems where rheological constraints of the lithosphere, among othermodel parameters, exert a first-order control for plateau formation.https://doi.org/10.5194/egusphere-egu24-1765
UniMLR: Modeling Implicit Class Significance for Multi-Label Ranking
No full textExisting multi-label ranking (MLR) frameworks only exploit information deduced from the bipartition of labels into positive and negative sets. Therefore, they do not benefit from ranking among positive labels, which is the novel MLR approach we introduce in this paper. We propose UniMLR, a new MLR paradigm that models implicit class relevance/significance values as probability distributions using the ranking among positive labels, rather than treating them as equally important. This approach unifies ranking and classification tasks associated with MLR. Additionally, we address the challenges of scarcity and annotation bias in MLR datasets by introducing eight synthetic datasets (Ranked MNISTs) generated with varying significance-determining factors, providing an enriched and controllable experimental environment. We statistically demonstrate that our method accurately learns a representation of the positive rank order, which is consistent with the ground truth and proportional to the underlying significance values. Finally, we conduct comprehensive empirical experiments on both real-world and synthetic datasets, demonstrating the value of our proposed framework. Code is available at https://github.com/MrGranddy/UniMLR.https://doi.org/10.3233/faia251191https://dx.doi.org/10.48550/arxiv.2508.21772http://arxiv.org/abs/2508.21772https://doi.org/10.48550/arXiv.2508.2177
Evaluation of the Chemical and Cytotoxic Characteristics of Settled Office and House Dust
No full texthttps://doi.org/10.1007/s40710-025-00788-
Navigating Türkiye's Energy Horizon: A Bibliometric Exploration of Academic Contributions to Energy, Fuels, and Hydrogen Subjects
No full textThis paper aims to unveil the intellectual structure and knowledge flow within Türkiye's academic landscape, shedding light on influential research clusters and highlighting the interconnections between different research themes. The manuscript also synthesizes findings from a Web of Science database, elucidating the growth trajectories of Türkiye's contributions to the global discourse on energy, fuels, and hydrogen. Additionally, the role of interdisciplinary collaboration has been explored and the impact of Türkiye's research output on the international stage has been assessed. According to results, the oldest date goes back to 1972 for energy&fuels topic and 1989 for hydrogen topic. Whereas Ayhan Demirbas and Ibrahim Dincer are the most productive authors, Istanbul Technical University and Yildiz Technical University are the most productive institutions. Moreover, USA and Canada are the most efficient countries for colloborations. Last of all, while new trends in Energy&Fuels publications have been observed as machine learning, supercapacitor, nanoparticles, electric vehicle and graphene, new trends in hydrogen publications were observed as methanolysis, multigeneration, ammonia, thermodynamic analysis and graphene.https://doi.org/10.2339/politeknik.140989
Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy
No full textIn this study, the in vitro photodynamic therapy (PDT) activity of two zinc phthalocyanines (ZnPc1 and ZnPc2) was systematically examined in human umbilical vein endothelial cells, focusing on PDT-induced cytotoxicity, reactive oxygen species (ROS) generation, and inhibition of angiogenic processes. Both the ZnPcs demonstrated minimal cytotoxicity in the absence of light, confirming their safety as photosensitizers. ZnPc-PDT led to significant cell death via apoptosis. ZnPc1 exhibited enhanced ROS generation, particularly at elevated concentrations. Furthermore, ZnPc1-mediated PDT showed more pronounced inhibition of endothelial cell migration, invasion, and capillary-like tube formation than ZnPc2. Wound-healing assays revealed a substantial delay in human umbilical vein endothelial cell (HUVEC) migration following ZnPc1-PDT, which also displayed a more significant inhibition of VEGF-induced directional migration and invasion. Endothelial tube formation was more effectively disrupted by ZnPc1-PDT, even at lower concentrations, compared to ZnPc2. Collectively, these findings highlight the superior cytotoxic and anti-angiogenic properties of ZnPc1 compared with ZnPc2, highlighting its potential as a highly effective photosensitizer for photodynamic therapy. The ability of ZnPc1 to simultaneously target tumor cells and disrupt angiogenesis establishes it as a potent candidate for integrated cancer therapies that combine both antitumor and antiangiogenic strategies, offering a more effective approach to combat cancer progression.https://doi.org/10.1038/s41598-024-84674-9https://pubmed.ncbi.nlm.nih.gov/39833179http://dx.doi.org/10.1038/s41598-024-84674-9https://doaj.org/article/a4a521488e694b048d1dd1a85d4d89e
Mentoring Practices Among Turkish EFL Teachers
No full textThis study reviews research on mentoring programs and practices for EFL teachers in Turkey conducted between 2014 and 2024. Using Criterion Sampling, a purposive sampling method, 10 articles were selected and analyzed. Content and thematic analyses revealed three key themes: Turkish EFL teachers' mentoring program expectations, the roles and responsibilities of EFL teacher mentors in Turkey, and contextual factors influencing EFL teacher mentoring. These findings provide valuable insights into areas where mentor and mentee teachers can derive the most benefit and serve as a guideline for stakeholders in designing and implementing mentoring programs in Turkey.https://doi.org/10.4018/979-8-3693-8502-9.ch00
Spatial analysis of wildfire burn severity and urban exposure assessment in Southwestern Türkiye
No full texthttps://doi.org/10.1007/s41207-025-00850-
Enhanced Out of Boundary UWB Based Localization for Industrial Digital Twins
No full texthttps://doi.org/10.1109/iccworkshops67674.2025.1116231
An Improved Pointing Error Model for mmWave and THz Links: Antenna and Array Design Impact
No full texthttps://doi.org/10.1109/lcomm.2025.3529519https://doi.org/10.1109/LCOMM.2025.352951
Sustainability Practices and Financial Performance: Evidence from BIST Electricity Index
No full texthttps://doi.org/10.70322/ecolciviliz.2025.1000