Scholastic: Journal of Natural and Medical Education
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Activity of the Pro and Antioxidant System in Erythrocyte Membranes in Children with Primary and Recurrent Laryngotracheitis
No full textThe main importance in the pathogenesis of functional disorders of organs and systems in acute constrictive laryngotracheitis in children is respiratory insufficiency, manifested by a violation of external, pulmonary and tissue respiration, hypoxia and hypoxemia. Under the influence of hypoxia and hypercapnia, the functional state of the central nervous system and the neuro-reflex regulation of the vital activity of the body are disrupted. Metabolic changes occur as a result of dysfunction of the most important organs and systems in the body. Violation of gas exchange and redox processes, hypoxia and hypoxemia lead to activation of anaerobic oxidation of under–oxidized metabolic products. Under the influence of hypoxia, bacterial toxins, products of impaired metabolism and changes in hemodynamics in children with acute stenosing laryngotracheitis, violations of the function of vital organs are noted. These changes are accompanied by an increase in the activity of LPO processes and the restructuring of the antioxidant protection systems of red blood cells
Features of Healthy Colonization of the Intestine in Children
No full textUntil recently, it was believed that the intestines of the fetus in the womb are sterile (except in cases of intrauterine infection). Previously applied culture methods (growing bacteria on nutrient media) made it difficult to identify representatives of the microbiota in biological samples. However, modern molecular genetic technologies have made it possible to detect the content of microorganisms in the meconium, placenta and amniotic fluid. The flora of the original feces turned out to be quite diverse, it is dominated by staphylococci and enterobacteria. The microbiome of the placenta and amniotic fluid is not diverse, it is dominated by proteobacteria. The microbiome of the amniotic fluid affects the formation of the intestinal microbiota of the fetus, and the microbial composition of meconium depends on the duration of gestation. This proves that the process of formation of the intestinal microbiota of a child begins in the prenatal period and occurs under the influence of the transfer of microorganisms from the mother to the fetus. Thus, by influencing the microbiome of a pregnant woman, it is possible to influence the process of microbial colonization of the baby's intestines
Study of Residual Amounts of Rostbisol, Oxyhumate, Bahor and Dorilin in Wheat Grain
No full textGrowth stimulators are gaining great popularity in agricultural production, as they contribute to a significant increase in yield, provide improved quality of crops. Currently, new plant growth stimulators of domestic production are intended for introduction in agriculture of the Republic of Uzbekistan: Rostbisol, Oxyhumate, Bahor and Dorilin
Synthesis of Starting Compounds and Their Alkylation Reactions in Different Solvents
No full textCarried out, the synthesis of the starting compounds, that they enter the reactions of alkylations in various solvents (DMF, acetonitrile and alcohol). The resulting compound was deter mined by the physico-chemical method IR, PMR and mass-spectroscop
The Course of Sepsis in Young Children
No full textSepsis is a confirmed or suspected infection with the development of life-threatening multiple organ dysfunction (MOD) of the internal organs due to dysregulation of the body's response to infection
Irritable Bowel Syndrome Clinical and Immunological Features in Adolescents
No full textAccording to the authors, the affected gut syndrome in most cases occurs in conditions of comorbidity. The affected intestine syndrome in adolescents against the background of immunological changes in the blood usually occurs in conjunction with atopic dermatitis, chronic cholecystitis and food allergies. Under observation were 110 patients with irritable bowel syndrome aged 14 to 45 years, who underwent immunological blood tests
Effect on the Organism When Chronic Administration of a New Phytopreparation
No full textMedicinal plants play an important role in traditional and modern medicine. Herba Meliloti l. and Achillea filipendulind L. dry extracts did not show any specific changes related to the histostructure of vital internal organs and the effects on organs. Correspondingly, some changes were observed in the organs of rats in the control group. These changes may be related to the conditions of the food and animals in the vivarium, because these changes were noted at the same level in the vital organs of the animals of both control and experimental groups. The studied dry extract did not cause drug-related pathological changes in animals at the studied doses (100 and 500 mg/kg). Taking into account that some of the noted changes are transient, it is possible to apply the dry extract of the studied plant collection to medical practice
Ethiopatogenesis, Rehabilitation, Profilacy, and Treatment Methods for Postinsult Survivors
No full textThe majority of strokes (about 89%) are ischemic, 17% are intracerebral hemorrhages, and about 3% are subarachnoid hemorrhages. According to the European researches, for each 100 000 of the population there are 600 patients with consequences of stroke, and 60% of them are invalids. Due to the aging of the population, there is an increase in the incidence of stroke, which makes stroke prevention (including recurrent strokes) and rehabilitation of stroke patients an important medical and social problem
Features of the Clinical Course of Abscesses Liver on the Background of Diabetes
No full textThe clinical course of patients with liver abscess (AP) on the background of diabetes mellitus (DM), the results of surgical treatment and their complications were evaluated. In 31 (36%) of the 86 patients receiving treatment at the clinical base of Buchgasse, was diagnosed with diabetes. As a result of the study, patients with DM disease have features of the clinical course of AP that lead to severe complications. AP puncture on the skin side reduces diagnostic errors, allows open surgical treatment of abscesses with a size greater than 120 mm, and leads to better treatment results. These patients should be treated together with an endocrinologist
Minimally Invasive Interventions in Portal Hypertension Complication with Esophageal and Gastric Varicose Veins
No full textPurpose: when bleeding from esophageal and gastric varices is observed in patients complicated by portal hypertension and to prevent further bleeding, using old methods (use of Sengestaken-Blackmore probe, permanent ice pack in epigastric area and lower third of thoracic area, large operative wounds) choosing the modern best minimally invasive intervention without leaving or hurting.
Material and methods. Staged endoscopic practice in 2020-2022 in all 32 patients who re-applied to the multidisciplinary clinic of the 1st faculty and hospital surgery department of the Tashkent Medical Academy in inpatient conditions of portal hypertension (PH) with bleeding complications from esophageal and gastric varices (EGV) done.
Results and their discussion. Endoscopic sclerotherapy (ES) is preferred when there is a high risk of bleeding from varicose veins detected during surveillance endoscopy or within 6-24 hours after initial conservative therapy and balloon tamponade. If bleeding has stopped on its own during the examination, ES is considered an indication to prevent rebleeding.
Conclusion: We do not want to see this method as a cure, but we consider it as a method that can help the patient in an urgent situation, and after this method, in order to prevent bleeding, prolong the patient's life and reduce other complications, it is necessary to carry out endovascular operation, and then liver transplantation