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The Effects of Co-Administration of Mangiferin and Artemther-Lumefantrine on Hematological Indices of Plasmodium Berghei Berghei-Infected Swiss Albino Mice
Get PDFMalaria, caused by the parasite Plasmodium falciparum, is prevalent in Nigeria, with an average occurrence rate of 75%. However, it is possible to cure this disease. Chemical-based drugs often induce hematological abnormalities in blood tissues when employed as a treatment approach. This study was conducted due to the need to investigate the effect of co-administration of mangiferin and artemether-lumefantrine on hematological indices of plasmodium berghei-infected Swiss albino mice. Forty-two (42) albino Swiss mice were divided into seven groups, with four groups infected with the blood of highly parasitized P. berghei-infected mice, while three were control groups. Artemether-lumefantrine (AL) was administered as the standard drug, and Mangiferin was used for treating the parasite. Group 1 was the normal control and received normal feed and water ad libitum. Group 2 was infected with P. berghei. Groups 3 and 4 were given 8 mg/kg body weight of artemether-lumefantrine and 410.79 mg/kg of mangiferin, respectively. Groups 5 and 6 were infected with P. berghei and treated with 8 mg/kg body weight of artemether-lumefantrine and 410.79 mg/kg of mangiferin, respectively. Group 7 was infected with P. berghei and treated with artemether-lumefantrine and mangiferin at doses of 8 mg/kg and 410.79 mg/kg body weight, respectively. The animals were sacrificed, and blood was obtained for the estimation of hematological parameters. In the study, giving antimalarial drugs and mangiferin together had a big effect on the production of red blood cells, the decrease in infection, and the clumping of platelets in mice that were infected with P. berghei. The study recommends further research to look into the long-term effects and safety issues of giving mangiferin along with antimalarial drugs in cases of uncomplicated malaria
IMPROVING THE INVESTMENT ACTIVITY OF INSURANCE COMPANIES
Get PDFThe article explores the formation and use of the financial resources of insurance companies, the assessment of the profitability of Investiture operations, a model that will help optimize their investiture activities and improve their financial mechanisms. And proposals were developed to improve the efficiency of the investision portfolio of insurance companies
The Role, Significance and Need For Clustering of Fruits and Vegetables In Ensuring Food Security
Get PDFThe article highlights the role, importance of fruit and vegetable production and the need for clustering in ensuring food security. Definitions and approaches of economists and industry experts to the concept of food insecurity are studied. In order to improve the provision of food safety, proposals and recommendations have been developed for the development of fruit and vegetable growing and the organization of a cluster system
Concept and Discourse of “Heimat”
Get PDFThe article describes the contemporary state of the Heimat discourse in German culture. The era of globalization has triggered a new wave of interest in this subject, which has given rise to new ideas and accounts for new approaches to the concept Heimat. For a long time the notion, Heimat has been ideologically and politically connoted. Nowadays this notion is regarded as complex, ambiguous and hard to define. The talk focuses on its cultural aspect and the variety of its definitions
Predictive Analytics for Strategic Workforce Planning: A Cross-Industry Perspective from Energy and Telecommunications
Get PDFThis paper explores the integration of predictive analytics into strategic workforce planning, highlighting the transformative impact of artificial intelligence (AI) and machine learning advancements. With a focus on the energy and telecommunications sectors, the study examines the incorporation of predictive models into HR systems and processes, underlining the strategic benefits for long-term business planning. The evolving nature of work, including remote work paradigms and the gig economy, underscores the necessity for adaptable workforce strategies. The research anticipates a significant role for predictive analytics in shaping future organizational competencies and competitive advantages across various industries. The study concludes with the potential for cross-industry application of predictive analytics, suggesting an expansive future for data-driven strategic planning in navigating the complexities of the modern workforce
Structural and Semantic Analysis of Phraseological Units with Zoonyms in Russian, English and Uzbek Languages
Get PDFThe presented scientific study focuses on the structural and semantic analysis of phraseological units with animal components in different languages like English, Russian, and Uzbek. This study is aimed at analyzing the semantic and structural features of phraseological units with animal expressions in three languages. The object of the research is the phraseological units with animal idiom expressions that are shared by all three languages
Crisis Management Leadership Study: Case Analysis Report
Get PDFThis article intends to examine the importance of conveying information in a timely manner, ensuring message clarity, and tailoring communications to suit the specific needs of the target audience. These factors are important to maintain transparency and trust during a crisis. The method used in this research is a literature study method by taking several articles in Scopus indexed journals based on the years 2010-2023, based on fields, and also based on foreign language articles. The analysis used in this research is literature review analysis. Data in the context of a literature review involves the systematic examination and synthesis of existing research findings and data related to a particular topic or research question. In the context of educational research. The results of this research emphasize the importance of leadership qualities such as empathy, adaptability, and clear communication in managing crises effectively. Leaders who demonstrate empathy and actively listen to the concerns and needs of their teams and stakeholders will be better prepared to provide necessary support and guidance during a crisis. They must prioritize clear and timely communications, leveraging multiple channels to reach all stakeholders and address potential misinformation or confusion. Additionally, leaders must be adaptable and open to changing circumstances, continually reassessing their strategy, and making necessary adjustments
Coastal Dynamics in Jayapura City, Papua: A Literature-Enriched Study
Get PDFThe investigation focuses on understanding land use and cover patterns in Jayapura City, along with drivers and climate change impacts in coastal areas. It explores tourism's role in coastal land use and assesses its sustainability. Using a comprehensive approach combining literature review and on-the-ground data collection, the study identifies knowledge gaps and key variables. It gathers site-specific data to validate findings and inform evidence-based recommendations for resilient coastal management. Socioeconomic aspects, including impacts on local communities and indigenous groups, are considered. This research aims to promote sustainable land use practices and address the challenges posed by climate change and tourism in coastal areas
The Relationship Between Giving Yellow Pumkin to the Tining of Colostrum Excretion by Postpartum Mothers at Home Knife Regional Hospital
Get PDFBreast milk is an emulsion of fat in a solution of protein, lactose and organic salts secreted by the mother's two breast glands and is the best food for babies aged 0-6 months (Bahiyatun in Ciselia & Syafriani, 2023) The 2021 Central Kalimantan Health Service Performance Report achieved the percentage of exclusive breastfeeding in Pulang Pisau Regency of 50.1%, ranking in the 3rd lowest of the 14 districts in Central Kalimantan (Central Kalimantan Health Service, 2021). According to data on the achievement of Pulang Pisau Hospital Quality indicators in 2022, exclusive breastfeeding coverage is <50% of the target standard of 100%. Objective: To analyze the correlation between public knowledge and the use of drugs for toothache in the working area of the Asam- Asam Public Health Center. Methods: This research design method uses a post test only control group. The sample for this research was postpartum mothers at Pulang Pisau Regional Hospital. The sampling technique uses the Non Probability sampling method with Purposive Sampling technique. Statistical tests use the Chi Square test. The population in this study consisted of 56 postpartum maternal patients. The sample in this study was 30 postpartum mothers who were treated at Pulang Pisau Regional Hospital. Results: Based on the research results, it is known that the frequency distribution of respondents is based on postpartum mothers who were given pumpkin which produced colostrum <24 hours with the highest number being 9 people with a percentage (60.0%) and the least in the intervention group whose colostrum production was >24 hours with a total of 6 people. with a percentage (40.0%). Conclusion: There is a significant relationship between giving pumpkin and the time of colostrum discharge in postpartum women at Pulang Pisau Regional Hospital
Character Sketch Of Wide Sargasso Sea
Get PDFWide Sargasso Sea is a novel by Dominican British author Jean Rhys. It is a story of Antoinette Cosway and her descent into madness at the hands of the cold-hearted and money-hungry Mr. Rochester. It was first published in 1966 and the novel is divided into three parts. Adapted from Charlotte Bronte’s “Jane Eyre” Rhys wrote Wide Sargasso Sea in an attempt to explain Brote’s character, Berth Mason, the violently insane wife of Edward Rochester who was isolated from the rest of the world and locked in a third-floor room[1]. In this novel, Rhys illustrates the emotional trauma, Sexual repression, and social isolation that Antoinette faces at the hand of Rochester resulting in the loss of herself and her sanity.