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Clinical Outcome of Vitamin D Supplementation in Moderate and Severe COVID-19 Patients: A Randomized Clinical Trial
Get PDFThe COVID-19 pandemic has posed a major global health challenge, especially for individuals with underlying health issues. This study aimed to assess the clinical outcomes of vitamin D supplementation in patients with moderate to severe COVID-19 in a tertiary care hospital through a randomized clinical trial. Sixty-two SARS-CoV-2 positive patients were enrolled and divided into intervention (vitamin D supplementation) and control groups
The Crucial Role of Pharmacists in Dentistry: A Comprehensive Review
No full textThe field of dentistry goes beyond the skills of dental professionals alone. Collaborative efforts among different healthcare providers are crucial for comprehensive patient care. One such critical role is played by pharmacists in dentistry. Pharmacists bring their expertise in medications and their interactions to ensure the safe and effective use of drugs prescribed by dentists. In this article, we will discuss the vital contributions of pharmacists in dental care and their role in promoting oral health. 
Triple Antibiotic Paste: Boon to Dentistry
No full textMicroorganisms must be removed from the root canal (RC) and periapical region for endodontic success. A sterile state cannot be achieved with only endodontic instrumentation. Local administration of antibiotics has been studied in light of the development of non instrumentation endodontic treatment, tissue healing and lesion sterilization. Triple antibiotic paste (TAP) with metronidazole, ciprofloxacin, and minocycline works well for non-vital young permanent teeth and the RC pathogen. Present review of literature aims to discuss role of TAP in endodontic treatment. 
To determine Minimum Inhibitory Concentration (MIC) of Cefixime in Mahacef® Tablet 200mg and API Cefixime trihydrate compacted IP (API)
No full textBackground: Antibiotic resistance is rising to dangerously high levels globally. New resistance mechanisms are emerging and spreading, thereby threatening our ability to treat common infectious diseases. In places where antibiotics can be bought for human or animal use without a prescription, the emergence and spread of resistance is made worse. This study endeavours to determine minimum inhibitory concentration (MIC) of Mahacef® 200mg Tablet and Cefixime Trihydrate API, both supplied by Mankind Pharma Limited. Methodology: Antibacterial activity of Cefixime on Salmonella enterica subsp. enterica serover Typhimurium was determined by Agar Dilution Method with Mueller Hinton Agar. Available strain of Salmonella enterica subsp. enterica serover Typhimurium (ATCC® 14028™) was used with Inoculum size was approximately 1000 cfu / plate. Dilutions were prepared in Phosphate buffer (pH 7.0, 0.1 mol/L) for Mahacef® 200 mg Tablet and Cefixime Trihydrate API, and used for the study. Results: Findings of this study demonstrate that both Mahacef® 200mg Tablet and Cefixime Trihydrate API have shown excellent antibacterial activity in vitro. MICs for the drug product as well as for the drug substance (API) are found to be 0.1 µg/mL against Salmonella enterica subsp. enterica serover Typhimurium. Conclusion: Mahacef® 200mg andCefixime Trihydrate API clearly establish support for its antimicrobial effectiveness and therefore, support values determined MIC for the viewpoint of medical fraternity that Cefixime is effective for management of typhoid fever. 
The Role of ChatGPT in Orthodontics: A Game Changer in Patient Engagement and Education
No full textChatGPT, an AI chatbot, has the potential to revolutionize the field of orthodontics by providing valuable support to orthodontists, staff, and patients. By leveraging its natural language processing capabilities, ChatGPT can assist in several ways, including answering patient questions, providing educational information about orthodontic treatments, offering post-treatment guidance, and even supporting staff in managing administrative tasks. The implementation of ChatGPT in orthodontic practices can improve patient satisfaction, streamline communication, and ultimately enhance the overall orthodontic experience for both patients and practitioners. This abstract provides an overview of the role of ChatGPT in orthodontics and highlights its potential impact on the field
Lesion Sterilization Tissue Repair and Recent Advances: A Review
No full textLesion sterilization tissue repair (LSTR) is an emerging approach in dentistry, aimed at eliminating infectious microorganisms from the root canals and promoting tissue repair. This review provides a comprehensive overview of the principles, techniques, and recent advances in LSTR. The traditional root canal treatment focuses on complete debridement and disinfection of the root canal system. However, LSTR offers an alternative approach by employing a triple antibiotic paste (TAP) consisting of metronidazole, ciprofloxacin, and minocycline. This antibiotic combination has shown promising results in eliminating the root canal microbiota, particularly in cases of immature teeth with open apices and necrotic pulps. 
The Role of Artificial Intelligence in Physiotherapy: A Comprehensive Review
No full textThis paper explores the application of artificial intelligence in the field of physiotherapy. It delves into the various ways in which AI technologies are revolutionizing the assessment, diagnosis, treatment, and management of musculoskeletal and neurological conditions. The advantages and limitations of AI in physiotherapy are discussed, providing a comprehensive overview of the subject. The paper concludes with a discussion on the future prospects and potential impact of AI on the field of physiotherapy. 
Immediate Loading of Single Implant in the Aesthetic Zone: A Case Report
No full textAn implant-supported restoration in the anterior zone must produce the best possible aesthetic outcome. Providing rapid interim restorations after implant surgery has been suggested as a preferable course of therapy in the aesthetic zone. Following implant implantation, a well contoured interim restoration reduces alterations to the hard and soft tissues surrounding the implant. The aesthetic result and, thus, patient satisfaction may be improved as a result. To get the desired outcome, several prosthetic and surgical components must be properly designed and carried out. This case report describes the immediate loading of a single implant in the aesthetic zone. 
ChatGPT : Transforming Face of Dentistry
No full textIn recent years, artificial intelligence (AI) has found its way into numerous industries, transforming the way we work and live. Dentistry is no exception, as AI powered technologies are revolutionizing the field, making it more efficient and enhancing patient care. One such breakthrough is the application of ChatGPT in dentistry. ChatGPT, powered by OpenAI, is a powerful language model that can comprehend and generate human-like responses, enabling dentists and their teams to leverage its potential in a multitude of ways. This article explores how ChatGPT is being applied in dentistry and the benefits it brings to both professionals and patients. 
Understanding Aphthous Ulcers: Causes, Symptoms, and Management
No full textAphthous ulcers, also known as canker sores, are a common and painful condition affecting the oral mucosa. This review article aims to provide an in depth understanding of aphthous ulcers, including their causes, symptoms, and management. The article examines the different types of aphthous ulcers, their epidemiology, etiology, clinical presentation, and current treatment options.