Malaysian Journal of Medical and Biological Research
Not a member yet
144 research outputs found
Sort by
Homoeopathic Treatment of Pituitary Adenoma: A Case Report
Full text linkMost pituitary adenomas are slow-growing and benign, which means they are not cancer and do not spread to other parts of the body. They generally have a slow but severe impact on vision due to compression of the optic nerves, optic chiasm, and cavernous sinus. However, as they grow big they can put pressure on nearby structures, such as the nerves that connect the eyes to the brain and cause symptoms. Pituitary adenomas are the third most common intracranial tumor and arise from the pituitary gland. An individual case is presented in this paper with radiological evidence (MRI) of a large lobulated intrasellar mass (3.0 cm transversely, 3.5 cm craniocaudally and 2 cm anteroposteriorly) with supra-sellar extension is causing elevation of the floor of the 3rd ventricle of the brain. Pituitary macroadenoma and hemorrhagic foei, pituitary apoplexy, and pituitary adenomas were founded by different CT scan and MRI reports in different laboratories. The patient was treated with constitutional homoeopathic medicines – Natrum muriticum-m/1, 16 doses up to Natrum muriticum-m/20, 16 doses each from 26/04/2014 to 07/08/2017. Before treatment imaging was done several times from 6/04/2011 to 12/01/2012showed complete resolution of the pituitary adenoma and during treatment3 follow-up imaging was done on 25/07/2015 and 06/08/2017. This case report reviews the clinical presentation, homoeopathic management, and treatment of the major classification of pituitary adenomas and call attention to the need for repertorization in individualized homoeopathic prescription. It is hoped that if this type of clinical research continues in the future, homeopathy will have a breakthrough result and it’s symptomatic medical treatment will play a beneficial role in the near future from the deadly evils of various types of chemotherapy, radiotherapy, or combined therapy
Efficacy of Myrmecodia Platytyrae (MyP) Water Extract in Reducing Cholesterol Level in Hypercholesterolemia Induced Sprague Dawley Rat
Full text linkMyrmecodia plant or ant-nest plant is from Rubiaceae family. Rubiaceae are mainly tropical woody plants, consist mostly of trees and shrubs and can be found in temperate regions. Myrmecodia platytyrea (MyP) are believed to have medicinal value. This study was designed in order to investigate the effect of MyP extract as anti hypercholesterolemic agent. The results showed that treatment of MyP can significantly reduce (p<0.05) low density lipoprotein (LDL) compared to negative control group. The extract was significantly increase (p<0.05) high density lipoprotein (HDL) concentration compared to negative control group. Besides that, MyP increased fecal cholesterol and fecal bile compared to normal control group. It was also found that lipid profile was significantly decreased (p<0.05) in MyP treatment group. All biochemistry data showed that MyP water extract was not toxic at all
Assessment of Eucalyptus Globulus Coppice Yield in the Highland Areas of North Shewa, Ethiopia
Full text linkOne of the old traditional methods of silvicultural management is coppicing. Many woody species produce new shoots successfully after coppicing. Regeneration of forest through coppice can be used for short rotation of tree to produce wood biomass for construction and fuel purposes. There are different levels of coppice practiced in Eucalyptus globulus plantation in the highland areas of North Shewa. However, there was no evidence or study which coppice levels can give high yield. Therefore, the objective of this study was to compare yield of E. globulus at different coppice level in the highland areas of North Shewa, Ethiopia. Fifty sampled plots were purposively selected for this study. Volume, mean annual increment, stump height and diameter, stem number and harvesting age were determined from sampled plots. The results revealed that there was no yield difference (p> 0.05) between zero, first, second and third coppice levels. However, stump diameter and number of shoots per stump, stump height were significantly different among 1, 2, 3 coppice levels (p<0.05). Number of shoots were positively correlated with stump diameter and height (r = 0.77, r = 0.72) respectively. Farmers mostly coppice E.globulus from November to December and from April to June. Although statistically there was no yield difference between coppice levels, as farmers described the first coppice has higher yield than other coppice levels. The numbers of shoots per stump were higher in the second and third coppice and this could affect stem quality especially at early stage. Altogether the mean number of stems per hectare was 10812 which is higher than previous studies. Therefore, early silvicultural activities like thinning, early coppice management and pruning has to be done to increase wood stem quality and to promote growth as well.
 
The Impact of Hospital Supplier Integration on Hospital Performance in Pakistan
Full text linkThe aim of this research is to analyze the Supplier Integration on performance of Hospitals within Pakistan. Four factors of supplier integration are identified as Logistics Integration (LI), Information Technology (IT), Cost Reduction (CR) and Information Sharing (IS) which have been analyzed using Smart PLS. Sample of 299 workers of hospitals is obtained using structured questionnaire comprising of 21 questions where the responses were measured on Likert Scale. Data was studied using SEM (Structural Equation Modelling). It was concluded that information sharing, information technology and cost reduction have significant impact on hospital performance while logistics integration has less significant impact on the hospital performance in Pakistan. The scope of this research is to conclude the factors involved in enhancing the performance of Hospitals by bringing about supplier integration.
 
COVID-19 in Italy: Remedies to Reduce the Infections and Deaths
Full text linkCOVID-19 is a novel (new) coronavirus fatal disease caused by SARS-COV-2 (2019-nCoV). The outbreak of this pandemic first has been identified in Wuhan, Hubei Province, China on 1 December 2019, and has spread worldwide very quickly. It is now a major global health threat. After the World War II, the world faces such a major challenge in health sector and economy. The virus is transmitted human-to-human through the respiratory system. From the poor to the rich, infants to old, every people are infected from this virus. The disease spreads in Italy very fast and the north of the country is mostly affected. Lombardy Region is the most infected region in the country. An attempt has been made here to discuss the aspects of infection and deaths due to COVID-19 in Italy.
 
Anogenital Warts Prevalence and Associated Risk Factors among MSM Population in Surakarta, Indonesia
Full text linkTo know anogenital warts prevalence and its correlation with HIV infection in men who have sex with men (MSM) population in Surakarta, Indonesia. To identify risk factors associated with anogenital warts among MSM population in Surakarta, Indonesia.
This cross-sectional study collects data from MSM population in Surakarta, Indonesia. Patients are MSM who joined monthly mobile clinic held by the health government of Surakarta and those who attend the Voluntary Consultation and Testing Clinic of Dr. Moewardi General Hospital. Risk factors were asked using questionnaire. Physical examination was used to diagnose anogenital warts, and took blood samples for HIV screening.
From 190 subjects, 25 (13.1%) had anogenital warts, and 17 (8.9%) are HIV positive. Anogenital warts increase the odds of having HIV infection by 5.18 times. Risk factors that contribute to anogenital warts include age 25-34 years old (OR= 3,729) and a history of drug abuse (OR= 7.184).
This research only uses simple physical examination to diagnose anogenital warts, and the small study subjects may not be representative of general MSM population in Indonesia.
Age 25-34 years old and history of drug abuse are substantial risk factors for anogenital warts. Having anogenital warts infection increases the odds of acquiring HIV. This study highlights the importance of STD screening especially in high-risk population such as MSM, which currently is still neglected by the Health Department of Indonesia.
 
Homeopathic Approach to COVID-19: A Review
Full text linkNovel coronavirus 2019-nCoV-2 infection, also known as COVID-19, has a pandemic outbreak, and recent studies show various limitations, including treatment. This virus is chiefly infecting the respiratory tract (RTI) and resulting in Severe Acute Respiratory Syndrome. Many developed countries, including Italy, England, and the United States of America (USA), are facing many casualties. Unlikely, no specific treatment protocol is available till today. Homeopathic medicine is a branch of alternative medicine, practiced on individualized symptoms similarity. However, historically it has potential in treating epidemic infections like scarlet fever, typhoid, and cholera. In the treatment of RTI and pneumonia, several homeopathic medicines have proven efficacy. This review on the utility of homeopathic medicine might guide the physician to prevent COVID-19 contagion. Homeopathic medicines can help humanity with conventional medical methods to prevent this global catastrophe
Studies on the Biology and Eco Physiology of Sesame Seed Bug, Elasmolomus Sordidus Fabricius, at Kafta - Humera Sesame Fields
Full text linkThe experiment was conducted in the plant protection laboratory of the Humera Agricultural Research Center to study the biology of sesame seed bug, Elasmolomus sordidus (Fabricius), Hemiptera: Lygaeidae. E.sordidus is considered as the most important harvest and post-harvest insect pest of sesame in North western Ethiopia. The rearing and other tests were conducted in the laboratory at 28-330C and 50 to 65% RH. The result of this laboratory investigation indicated that the mean egg incubation period was 5.4± 0.05 days while the total mean nymphal duration took 18.44±0.10. A mean adult lifespan of 20.24±0.19 days was recorded. The mean lifespan from egg to adult death was 44.08 days, which range from 32-54 days. The reproductive period was 7.08 ± 0.26 days and the peak laying period was on the first and second day of its reproductive days. Even though E.sordidus was present the whole year high outbreak was recorded at harvest (October) and continued up to January, which afterward declined until the next harvest time.
 
Effects of Ziziphus Spina-Christi (L.) on Selected Soil Properties and Sorghum Yield in Habru District, North Wollo, Ethiopia
Full text linkZiziphus spina-christi is a multipurpose tree which grows naturally on the farm lands in Habru district. Since, the effects of this tree on soil and crop have not scientifically quantified; this study has been carried out with the aim of assessing the effect of Ziziphus spina-christi on soil physicochemical properties, grain and biomass yield of sorghum.Five isolated and nearly identical Ziziphus spina-christi tree growing on farm lands with similar site condition were selected and canopy coverage of each tree was divided into four radial transects. Soil samples from three horizontal distances: 1.2m, 2.9m and 15m with two soil depths (0–15cm and 15-30cm) were taken for analysis of soil physico- chemical properties. Three quadrates 1m x1m at each transect and distances were laid for sorghum grain yield and biomass estimation. The result shows that soil pH, EC, CEC and soil texture were not significantly (p>0.05) influenced by Ziziphus spina-christi tree, whereas soil bulk density, soil moisture content, total nitrogen, organic carbon, available phosphorus and exchangeable cation (Mg, Ca and K) were significantly (P<0.05) influenced mainly due to higher organic matter input through litter fall, root biomass, uptake and return of nutrients from deeper soil profiles under the tree canopies. While the grain yield of sorghum and above ground biomass were not statistically significant (p>0.05).Hence, retaining of this tree on crop land improves the soil fertility status.
 
Status and Decline Causes of Fish Diversity of Bhawal Beel, Bangladesh
Full text linkBeel is one of the ancient types and obviously a fascinating one due to its biodiversity and ecological importance in local and national perspective of Bangladesh. The Bhawal beel is one of important beels and excellent habitat for small indigenous species (SIS). The present status and decline causes of Bhawal beel was studied from March 2016 to February 2017. Data collection was carried out from four villages of Achim union under Fulbaria upazila. Questionnaire Interview (QI), Focus Group Discussion (FGD) and cross-check Interview were done to obtain data related to status and decline causes of fishes from the fishermen and resource person. A total of 56 species of fish including prawn under 10 orders and 23 families were recorded from thebeel. Cypriniformes (33.93%) was the most dominant order followed by Siluriformes (21.43%), Perciformes (19.65%), Channiformes (7.14%), Synbranchiformes (7.14%), Decapoda (3.58%), Cyprinodontiformes (1.78%), Osteoglossiformes (1.78%), Beloniformes (1.78%) and Tetraodontiformes (1.78%). Among the recorded families Cyprinidae was the most dominant family contributing 17 species. The availability status of observed species were remarked in four categories and obtained as available (44.64%), seasonal (19.64%), rare (16.08%) and very rare (19.64%). Decline causes like overfishing, use of illegal fishing gear, siltation, katha fishing, and abstraction of water for irrigation, catching of fry and brood fishes, lack of connection of beel with Banar river and absence of proper beel management policy were observed as major threats for fish diversity. About 13species were found threatened (1 critically endangered, 5 endangered and 7 vulnerable) which may extinct in near future due to proper management of the beel fishery. The present study recommends minimizing of all these impediments. Besides Community Based Fisheries Management (CBFM) and beel nurseryis essential to save the valuable fish diversity of Bhawal Beel on which local livelihood depends.