International Journal for Innovation Education and Research
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Bacterial nanocellulose and long-chain fatty acids interaction: an in silico study
Get PDFChronic wounds are a big challenge in contemporary society, as they lead to a decrease in life-quality, amputations and even death. Infections and biofilm formation might occur with chronic wounds, due to the higher susceptibility to antibiotic multi-resistant bacteria. In this situation, novel wound dressing biomaterials are needed for treatment. Thus, the aim of this research was to evaluate a possible BNC interaction with tucumã oil/butter-derived fatty acids, as this system could be a promising biomaterial for wound treating. The interaction between cellobiose (BNC basic unit) and four fatty acids was evaluated by ab initio simulations and density functional theory (DFT), through SIESTA code. Molecular docking was also used to investigate the effect of a possible releasing of the studied fatty acids to the quorum-sensing proteins of Pseudomonas aeruginosa (gram-negative bacterium) and Staphylococcus aureus (gram-positive bacterium). According to ab initio simulations, the interaction between cellobiose and fatty acids derived from tucumã oil/butter was suggested due to physical adsorption (energy around 0.17-1.33 eV) of the lipidic structures into cellobiose. A great binding affinity (∆G ranging from 4.2-8.2 kcal.mol-1) was observed for both protonated and deprotonated fatty acids against P. aeruginosa (LasI, LasA and Rhlr) and S. aureus (ArgA and ArgC) quorum-sensing proteins, indicating that these bioactive compounds might act as potential antimicrobial and/or antibiofilm agents in the proposed system. Hence, from a theoretical viewpoint, the proposed system could be a promising raw biomaterial in the production of chronic wound dressings
And now woman? An analysis of the career and family of university women from a Public University
Get PDFThe study investigated the main obstacles and/or opportunities that women students from a public university experience when reconciling career and family. For data analysis, inferential statistics were used. The population comprised women students from the last year of the Administration course at the State University of Paraná – UNESPAR/Campus Paranaguá. The sampling was of the simple random type. In order calculate the sample size, a tolerable sampling error of 10% was used. Most of the interviewees work outside the home, are aged between 18 and 29 years old, they are single, do not have children and their income is between one and three minimum Brazilian wage. The multiplicity of simultaneous roles often assumed by some women (mother, housewife, student, wife among others) requires an effort, sometimes undervalued, to reconcile and adapt the demands of the family, social, professional and academic environment. Despite the existence of a support network, the challenges as a woman in reconciling the various activities make us reflect on whether such support actually is materialized in practice
Paradigms and Approaches in Educational Research
Get PDFThis article aims to discuss the concepts of paradigms and approaches in educational research. It is a literature review based on the significant and recognized books on the subject. The results indicate that at least three main paradigms are used in educational research and that the basic approaches are quantitative, qualitative, and mixed methods
Identification of Suppliers able to provide Hydraulic Fracturing Services in Unconventional Reservoirs and Risks associated with the Construction of these Wells
No full textAccording to the international agencies U.S. Energy Information Administration (EIA) and World Energy Council (WEC), Brazil is the 10th country in the world ranking of the largest holders of shale gas reserves, with 245 Tcf (trillion cubic feet) (6.9 Tcm – trillion cubic meters) of natural gas. Due to the low permeability of these formations, the so-called unconventional reservoirs, only become viable if stimulated through horizontal drilling and hydraulic fracturing techniques. These techniques, like any other ones, have associated risks that should be very well managed and mitigated. This article aims to show that the benefits, in terms of fostering the local economy, job creation and energy security, outweigh the risks since they are known and well managed. In addition, suppliers present in country, able to provide these services properly, with numerous successful cases around the world, are identified in the article as well
Design of four rotor aircraft with obstacle avoidance
No full textThe system uses TM4C123G as the core of quadrotor autonomous vehicle control, which consists of flight control module, power supply module, motor speed control module, optical flow sensing module, and target tracking identification module. The flight control module includes angle sensor, gyroscope, and TLS1401-LF module. The flight control processes the collected data through the chip (TM4C123G), and processes the data with PID control algorithm, while solving the PWM increment and decrement needed for the corresponding motor, adjusting the motor in time and adjusting the flight attitude. The binocular camera identifies the color of the pole tower and measures the distance, so that the distance between the aircraft and the nearest point of the pole tower is kept within 50±10cm. After detecting the red (green) tower as the center, fly around the tower clockwise (counter) for one week (top view). Finally, the OV7725 camera is used to identify the solid black circle mark of the landing point and land smoothly and accurately in the target area, thus realizing an efficient robot around the barrier
Extending artistic skills through music
No full textthis research deals with questions about Music Education in the Brazilian school context. Its general objective is to reflect on the relevance of Music Education for human and sociocultural development, enabling students to expand their artistic-musical skills, sensitivity and creativity, in addition to improving the quality of education. As for the methodology, this is a qualitative and bibliographical research, based mainly on authors such as Gardner and Fonterrada, among others. It makes a historical review of Music Education worldwide, with different conceptions, at different times and their contributions to the area in contemporary times. It is based on the Law of Guidelines and Bases of Brazilian National Education (LDB) No. 9,394/96 and Law 11.769, the latter that determines the obligation of Music Teaching in Brazilian schools since 2008. In its considerations, the law discusses the need for teacher training and Brazilian schools to invest more in Music Education, considering that it is a universal language that contributes to the entire educational process and, consequently, to integral human development
Effects of Public Governance on Economic Development of the Municipalities of the Metropolitan Region of Salvador
No full textThis research aims to identify the effects of public governance on the economic development of municipalities in the Metropolitan Region of Salvador (RMS) from 2015 to 2018. The statistical analysis was used in order to measure the association between public governance and the economic development of the Municipalities, using the Municipal Management Effectiveness Index (IEGM) as a governance proxy and the Gross Domestic Product (GDP) as a proxy for economic development per capita at current Municipal prices. This study is justified by the important reflection on the costs and benefits of implementing public governance mechanisms at the municipal level. According to recent literature and premises of IFAC and Supreme Audit Institutions, the application of public policies efficiently and effectively contributes to an improvement in public management with regard to transparency, integrity and accountability, which can result in advances in municipal economic development. The results of this research corroborate these studies, as they demonstrate that public governance positively and significantly influences the economic development of the thirteen municipalities analyzed
Motif: a digital guide to assist the use and selection of music tracks for audiovisual editing
No full textThe popularization of online video platforms has also increased the number of producers who, with reduced teams or composed of a single person, have an inexperienced profile in this activity. Thus, among the various specificities of the material produced, the sound issue tends to be underestimated, sometimes harming the message to be transmitted. The objective of the research was to develop a guide that would help the process of selection and use of music tracks, enhancing the audiovisual message. For the development of the digital solution, we used the methodologies of the Essential Competencies of Information Design (Simlinger, 2007) and Project E by Meurer & Szabluk (2010). As a result, we present the website Motif, with content on the use of music tracks in audiovisual material, based on emotions and musical characteristics, sensations, music track effects, soundtrack-based video editing, and a music tracks search tool, according to the listed concepts
Knowledge, attitude and influential factors in decision-making and organization of ecological based production systems of bananas in the Atlantic Forest of Rio Grande do Sul – Brazil
No full textThe main proposal of this work was to comprehend how internal factors influence the knowledge and decision-making of the farmers. Therefore, the production systems of ecological basis of banana in the Atlantic Forest in the state of Rio Grande do Sul – Brazil was observed. For that, 53 interviews have been carried out, which composed a non-probabilistic sample, and the data generated was analyzed through statistics and multivariate analysis tools. The results generated evidence for the comprehension that, in the organization of production systems, by the farmers, there is an important influence of their personal experiences and their values more closely connected to satisfaction and succession. Finally, it was observed that the elaborate construction of this work, considering the means of production, information system and regime of values, may be employed in different production systems
Analysis of antimicrobial, antibiofilm, and healing activity of lipid nanocarriers based on Tucuman butter (Astrocaryum vulgare), fixed oils from microalgae chlorella Homosphaera and from UVA seed Vitis vinifera
No full textTherapeutic alternatives of natural origin have been arousing the interest of large research centers that are looking for new bioactive molecules to treat numerous diseases in the context of public health. Among them, infectious diseases, which present antimicrobial resistance, deserve attention. The present study aimed to evaluate the antimicrobial activity of lipid nanocarriers (CLN), as well as the healing activity, arising from the association of tucumã butter with grape seed oil and another one containing microalgae oil. Two formulations were prepared using the high-speed homogenization technique, which was evaluated for antimicrobial action for 10 strains of great clinical importance, including a multiresistant and healing activity. The formulation with Chlorella homosphaera oil showed growth inhibition for the 10 strains tested, in addition to antibiofilm activity for 8 strains, bactericidal action for 3 of 3 isolates, and satisfactory healing action in 48 hours