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Alzheimer Hastasına Bakım Verenlerin Tanı Aşamasında ve Tedavi Sürecinde Yaşadıkları Sorunlar Üzerine Kalitatif Bir Çalışma
No full textAmaç: Alzheimer hastasına bakım verenlerin tanı aşamasında ve tedavi sürecinde yaşadıkları sorunların belirlenmesidir. Yöntem: Çalışma nitel araştırma yöntemine uygun olarak fenomonolojik desende tasarlandı. Çalışmanın örneklemini 16 Alzheimer hasta ve hasta yakını oluşturdu. Veriler derinlemesine görüşme yöntemi ile toplandı. Hasta yakınlarının düşünceleri kalitatif olarak verildi. Bulgular: Çalışmamızda; bakım verenlerin tümünün hasta yakını olduğu saptandı. Hasta yakınlarının, hekime başvurma sebebi olarak “unutkanlık” ve tanıyı ilk duyduklarında hissettiklerinde “üzüntü”, tedavi sürecine dair “endişe” ortak tema olarak bulundu. Sonuç: Alzheimer tanısı alan hastaların yakınların tedavi sürecinde hastalığın seyri konusunda belirsizlik yaşadıkları ve hastalığın ilerleyen evrelerinde hasta bakımı ile ilgili endişe duydukları belirlendi. Bu bağlamda; hastalık yönetiminde destek verebilecek kurumların yaygınlaştırılması ve sağlık çalışanları tarafından toplumun Alzheimer hastalığı hakkında farkındalığının arttırılması gereklidir
Analysis of accounting errors and fraud within the scope of forensic accounting: Supreme court decisions (2010-2024)
No full textBu çalışma, muhasebe hataları ve hilelerinin Türkiye'deki yargı kararları üzerinden sistematik bir şekilde analiz edilmesini amaçlamaktadır. Literatür taraması kapsamında, adli muhasebe ve hile konulu yüksek lisans ve doktora tezleri incelenmiş; bu tezlerde kullanılan yöntemler, örneklem türleri ve veri toplama teknikleri analiz edilerek alandaki mevcut yönelimler tespit edilmiştir. Bu tez çalışmasında Türkiye genelinde farklı mahkeme türlerinden toplanan 870 yargı kararı içerik analizi yöntemiyle incelenmiş; MAXQDA programı kullanılarak veriler tematik kodlara ayrılmıştır. Analiz sonucunda, muhasebe kaynaklı uyuşmazlıkların yaklaşık %80'inin muhasebe hilesi, yalnızca %20'sinin muhasebe hatası niteliğinde olduğu tespit edilmiştir. Hile türleri arasında zimmet (%19,07), nitelikli dolandırıcılık (%18,99) ve belge sahteciliği (toplamda %25'in üzerinde) öne çıkmaktadır. Bu durum, muhasebe sistemlerinin yalnızca bilgi üretiminden sorumlu değil, aynı zamanda suiistimallere açık bir alan olduğunu göstermektedir. İnceleme bulguları muhasebe hilelerinin gerek teknik gerekse etik ihlallerle doğrudan ilişkili olduğunu, bu nedenle yalnızca bireysel değil, örgütsel sorumlulukların ve iç denetim zaaflarının da dikkate alınması gerektiğini ortaya koymuştur. Bu kapsamda, yargı organlarının teknik uzmanlıkla desteklenmesi, adli muhasebe konusunda ihtisaslaşmanın sağlanması ve kurumlarda etik uyum sistemlerinin, şeffaflık ilkelerinin güçlendirilmesi önerilmektedir.This study aims t
Exploring the complex relationships between earthquake obsession and mental well-being among earthquake survivors: Serial mediation and moderated mediation analysis
No full textThis study examined the relationships between earthquake obsession, psychological well-being, future anxiety, and hope in adults who experienced the earthquakes in southern T & uuml;rkiye in 2023. The study sample consisted of 528 adults aged between 18 and 55 years. The results of the study showed that high earthquake obsession is associated with low mental well-being; however, high hope acts as a buffer in this relationship. At the same time, future anxiety mediates the relationship between earthquake preoccupation and mental well-being. In addition, we found that married individuals have more earthquake obsession and lower mental well-being than single individuals, and future anxiety has a more negative effect on well-being in single individuals. These findings will provide insights for mental health professionals to enhance well-being in intervention studies
Extra-gastrointestinal stromal tumor of the prostate - a case report and literature review
No full textExtra-gastrointestinal stromal tumors (EGISTs) primarily originate outside the gastrointestinal tract and are not associated with the walls of the stomach or intestines. They typically arise from the omentum, mesentery, peritoneum, retroperitoneum, and genitourinary regions. However, EGISTs originating from the prostate are exceedingly rare. Herein, a case is presented of an EGIST arising from prostatic tissue. The patient underwent radical prostatectomy. Histopathological examination revealed spindle-shaped tumor cells. Immunohistochemical analysis demonstrated positive expression of CD117, DOG-1, and CD34, leading to the diagnosis of a gastrointestinal stromal tumor (GIST). Radiologic staging showed no evidence of residual disease or metastasis; however, due to the high-risk nature of the tumor, adjuvant imatinib therapy was initiated. No recurrence or metastasis was observed during a one-year follow-up period, and the patient continues to be monitored regularly. This article also provides a comprehensive review of the clinical characteristics, histopathology, and treatment of EGIST cases reported in the literature
Determination of Disaster Preparedness of Nurses Working in Adult Internal Medicine and Surgical Emergency Department
No full textThe study was planned to determine the disaster preparedness of nurses working in the adult internal medicine and surgery emergency department. It is cross-sectional. In July and September 2023, 66 adult internal medicine and surgery emergency nurses in a public hospital and a university participated in the study. Face-to-face interviews were conducted using the Nurses' Individual Characteristics Form and Disaster Preparedness Perception Scale of Personnel Working in Pre-Hospital Emergency Health Services to collect research data. These forms were collected through face-to-face interviews. The total score of the scale used in the study was 111.15 ± 15.08. Mann-Whitney U, Spearman correlation test, and descriptive analyses were used to evaluate the data. It was determined that there was a significant positive relationship between the working year of the nurses participating in the study and the self-efficacy sub-dimension of the scale (p <0.05). It was determined that the benefit sub-dimension of female nurses was significantly higher than that of male nurses (p <0.05). The mean total scale score of nurses with a bachelor's degree was found to be highly significant compared to nurses with a high school degree (p <0.05). The mean total scale score of nurses who are not working in the disaster management process other than the COVID-19 pandemic was found to be highly significant compared to those who are involved in the earthquake management process (p <0.05). It was found that the level of disaster preparation of adult internal medicine and surgery emergency service nurses was slightly above the middle level. In addition, it was determined that experience, gender, education level, and the COVID-19 pandemic were effective in determining the preparedness of nurses for disasters. © 2025 Elsevier B.V., All rights reserved
THE ROLE OF ULTRASONIC CARDIAC OUTPUT MONITOR IN EVALUATING STROKE VOLUME VARIATION TO DETERMINE FLUID RESPONSIVENESS IN PATIENTS WITH SHOCK
No full textBackground: Dynamic assessment of cardiac output (CO) with passive leg raise (PLR), stroke volume variation (SVV), and pulse pressure variation (PPV) offer effective and safe methods to predict fluid responsiveness in patients with shock. The primary aim of this study was to evaluate the reliability of CO and SVV readings with the ultrasonic cardiac output monitor (USCOM) 1A device compared to PPV measurements in determining fluid responsiveness of patients in shock. Materials and Method: Intubated and mechanically ventilated patients aged 18-95 with shock admitted to the medical intensive care unit from June 2019 to December 2020 were included in the study. Fluid responsiveness was assessed using PPV from arterial monitoring and CO/SVV using the USCOM 1A device. CO, PPV, and SVV data were recorded before and after PLR. Results: Out of 145 shock patients, 92 were included. Before the PLR maneuver, 67 patients had PPV values above 12% and were stated as fluid responsive. The SVV index measured by the USCOM device demonstrated good sensitivity (85%) and specificity (96%) in identifying fluid responsiveness. The agreement with PPV was substantial (Cronbach's alpha reliability: 0.718 [P < 0.001]), and the index was internally consistent (kappa agreement: 0.707 [P < 0.001]). The SVV index moderately correlated with PPV (R: 0.588 [P = 0.001]). Regarding fluid responsiveness determined by PPV, the AUC value of SVV was 0.797 (0.701-0.894) (p: 0.001). Conclusion: SVV measured by the USCOM device is a reliable and practical tool for hemodynamic assessment in clinical practice, particularly when invasive methods are unsuitable
Effects of Lactobacillus acidophilus probiotic on the expression of fecal microRNA in rat colon cancer model
No full text[Abtsract Not Available
Investigation of the relationship of muscle strength and foot posture with balance in elderly and young individuals
No full textGiriş ve Amaç: Bu çalışmada genç yetişkin ve yaşlılarda kas kuvveti, ayak postür indeksi ve denge değişimini incelemek, ayrıca kas kuvveti ve ayak postür indeksi ile denge arasındaki ilişkiyi incelemek amaçlandı. Gereç ve Yöntemler: Çalışmada, genç yetişkin gruba Trakya Üniversitesi Sağlık Bilimleri Fakültesi Fizyoterapi ve Rehabilitasyon öğrencilerinden 52 gönüllü, yaşlı gruba Şarköy ve köylerinde ikamet eden 53 gönüllü (toplam 105 gönüllü) dahil edildi. Tüm katılımcıların demografik bilgileri, düşme ve hastalık geçmişlerine ek olarak ayak postürü Ayak Postür İndeksi (APİ-6), kas kuvveti El Kavrama Kuvveti (EKK), statik denge Tek Ayak Üstünde Durma Testi (TADT- SAĞ ve SOL) ve dinamik denge Modifiye Fonksiyonel Uzanma Testi (MFUT) ile değerlendirildi. Bulgular: Genç grubun yaş ortalaması 21,83 ± 1,823, yaşlı grubun ise 69,04 ± 5,313'tü. Gruplar arasında cinsiyet açısından fark bulunmamakla birlikte (p=0,680) kilo, boy ve beden kitle indeksinde istatistiksel fark bulundu (p0.05). Genç grupta EKKSAĞ ile MFUTÖN ve MFUTSAĞ arasında pozitif ilişki bulundu (r=0,429, p=0,002; r=0,354, p=0,010). Genç grupta APİ-6 SAĞ ile MFUTSAĞ ve MFUTSOL arasında negatif ilişki bulundu (r=-0,320, p=0,021; r=-0,302, p=0,030). Yaşlı grupta EKKSAĞ'ın TADTSAĞ, TADTSOL ve MFUTÖN arasında orta şiddette pozitif ilişki bulunurken (r=0,550, p<0,001; r=0,529, p=<0,001; r=0,596, p<0,001) MFUTARKA, MFUTSAĞ ve MFUTSOL arasında zayıf pozitif ilişki bulundu (r=0,377, p=0,005; r=0,450, p=0,00; r=0,430, p=0,001). Yaşlı grupta her iki tarafta ayak postürü ile TADT arasında zayıf negatif ilişki bulundu (rho=-0,299, p=0,030; rho=-0,330, p=0,016).vi Sonuç: Yaşlılarda gençlere göre daha zayıf kas kuvveti ve denge görülürken ayak postüründe fark bulunmadı. Gençlerde kas kuvveti ile dinamik denge arasında zayıf bir ilişkisi varken yaşlılarda hem statik hem dinamik denge ile daha güçlü bir ilişki vardı. Yaşlılarda ayak postürü statik denge ile ilişkiliyken gençlerde dinamik denge ile ilişkilidir.Background and Aim: The aim of this study was to investigate t
CuCrZr ja CuZn39Pb3 sulamite kulumiskäitumise eksperimentaalne võrdlus pin-on-disc meetodil toatemperatuurist kõrgematel temperatuuridel
No full textThis study investigates the wear behavior of the CuCrZr and CuZn39Pb3 alloys under varying thermal conditions while maintaining constant mechanical parameters using a pin-on-disc tribometer. The experiments were conducted at 25 degrees C, 100 degrees C, 200 degrees C, and 300 degrees C under a load of 7N, with wear rates, the coefficient of friction (COF), and hardness values evaluated for both alloys. CuCrZr demonstrated superior wear resistance, stable hardness, and con-sistent frictional behavior across all temperatures, attributed to its precipitation-hardening mechanism and thermal stability. In contrast, CuZn39Pb3 showed significant softening, higher wear rates, and erratic COF behavior at elevated temperatures due to the loss of lead's lubricating properties and matrix degradation. Scanning electron microscopy (SEM) analysis revealed less severe surface damage for CuCrZr compared to CuZn39Pb3, which exhibited pronounced delamination and debris for-mation. These findings highlight CuCrZr's suitability for applications involving elevated tem-peratures and significant tribological loads, as supported by calculated contact stresses. While CuCrZr demonstrates superior thermal stability and wear resistance, CuZn39Pb3 exhibits enhanced machinability due to the presence of lead, making it preferable for applications requiring ease of manufacturing