IYTE GCRIS Database (Izmir Institute of Technology)
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Studies on the Probiotic, Adhesion, and Induction Properties of Artisanal Lactic Acid Bacteria: To Customize a Gastrointestinal Niche To Trigger Anti-Obesity Functions
No full textThe primary goals of this work are to explore the potential of probiotic lactic acid bacteria's (LAB) mucin/mucus layer thickening properties and to identify anti-obesity candidate strains that improve appropriate habitat for use with the Akkermansia group population in the future. The HT-29 cell binding, antimicrobial properties, adhesion to the mucin/mucus layer, growth in the presence of mucin, stability during in vitro gastrointestinal (GI) conditions, biofilm formation, and mucin/mucus thickness increment abilities were all assessed for artisanal LAB strains. Sixteen LAB strains out of 40 were chosen for further analysis based on their ability to withstand GI conditions. Thirteen strains remained viable in simulated intestinal fluid, while most showed high viability in gastric juice simulation. Furthermore, 35.9-65.4% of those 16 bacteria adhered to the mucin layer. Besides, different lactate levels were produced, and Streptococcus thermophilus UIN9 exhibited the highest biofilm development. In the HT-29 cell culture, the highest mucin levels were 333.87 mu g/mL with O. AK8 at 50 mM lactate, 313.38 mu g/mL with Lactobacillus acidophilus NRRL-B 1910 with initial mucin, and 311.41 mu g/mL with Lacticaseibacillus casei NRRL-B 441 with initial mucin and 50 mM lactate. Nine LAB strains have been proposed as anti-obesity candidates, with olive isolates of Lactiplantibacillus plantarum being particularly important due to their ability to avoid mucin sugar consumption. Probiotic LAB's attachment to the colonic mucosa and its ability to stimulate HT-29 cells to secrete mucus are critical mechanisms that may support the development of Akkermansia
Social Logic of Space, Public Transport Accessibility, and Urban Logistics Interaction in Refugee Dense Districts of Izmir
No full textRefugees are an important issue in terms of the socioeconomic aspects of sustainable urban logistics. Uncertainties in their population sizes, places of residence and work make transportation decisions difficult. This chapter aims to examine access to public transportation and predict potential human movement in the refugee-dense districts of Izmir, which is the 8th city with the highest Syrian population in Turkiye. In this chapter, Syrians are considered refugees due to mass-forced displacement and social conditions. Using space syntax methods, segregated or integrated areas were identified, and the accessibility was measured by network analysis. Spatial configurations were evaluated based on population size and land use. Considering the size of the refugee population, the social logic of space is understood more realistically. Comprehensive strategies are needed for reducing spatial segregation and social exclusion of refugees, including land use planning, public spaces, and transportation services. Additionally, it is important to consider urban logistics ethics in this process. © 2024, IGI Global. All rights reserved
Exploring Student Information Management System Adoption Post Pandemic: Case of Turkish Higher Education
No full textMany aspects of our lives have changed during the pandemic including the accelerated adoption of technologies. Education was one of the segments that was disrupted by the pandemic, therefore Student Information Systems became critical at that time. This paper explores the adoption of Student Information Management Systems in multiple Turkish universities. The research model was adopted from a study conducted in the US, which is based on the Unified Theory of Acceptance and Use of Technology. More than three hundred students from seventeen universities responded, and the results indicated key factors of adoption. Furthermore, differences with the case in the US were identified. © 2024 Elsevier Lt
Continuous Flow Pyrolysis of Virgin and Waste Polyolefins: a Comparative Study, Process Optimization and Product Characterization
No full textUnder optimal process conditions, pyrolysis of polyolefins can yield ca. 90 wt % of liquid product, i.e., combination of light oil fraction and heavier wax. In this work, the experimental findings reported in a selected group of publications concerning the non-catalytic pyrolysis of polyolefins were collected, reviewed, and compared with the ones obtained in a continuously operated bench-scale pyrolysis reactor. Optimized process parameters were used for the pyrolysis of waste and virgin counterparts of high-density polyethylene, low-density polyethylene, polypropylene and a defined mixture of those (i.e., 25:25:50 wt %, respectively). To mitigate temperature drops and enhance heat transfer, an increased feed intake is employed to create a hot melt plastic pool. With 1.5 gmiddle dot>min-1 feed intake, 1.1 Lmiddle dot>min-1 nitrogen flow rate, and a moderate pyrolysis temperature of 450 degrees C, the formation of light hydrocarbons was favored, while wax formation was limited for polypropylene-rich mixtures. Pyrolysis of virgin plastics yielded more liquid (maximum 73.3 wt %) than that of waste plastics (maximum 66 wt %). Blending polyethylenes with polypropylene favored the production of liquids and increased the formation of gasoline-range hydrocarbons. Gas products were mainly composed of C3 hydrocarbons, and no hydrogen production was detected due to moderate pyrolysis temperature
Quantitative Performance Analysis of Blas Libraries on Gpu Architectures
No full textBasic Linear Algebra Subprograms (BLAS) are a set of linear algebra routines commonly used by machine learning applications and scientific computing. BLAS libraries with optimized implementations of BLAS routines offer high performance by exploiting parallel execution units in target computing systems. With massively large number of cores, graphics processing units (GPUs) exhibit high performance for computationally-heavy workloads. Recent BLAS libraries utilize parallel cores of GPU architectures efficiently by employing inherent data parallelism. In this study, we analyze GPU-targeted functions from two BLAS libraries, cuBLAS and MAGMA, and evaluate their performance on a single-GPU NVIDIA architecture by considering architectural features and limitations. We collect architectural performance metrics and explore resource utilization characteristics. Our work aims to help researchers and programmers to understand the performance behavior and GPU resource utilization of the BLAS routines implemented by the libraries
Effect of Partial Replacement of Sucrose With Stevia and Sucralose on the Physicochemical and Structural-Mechanical Properties of Apple Marmalade
No full textIn this study, low-sugar apple marmalade formulations were developed by partial replacement of sucrose with stevia and sucralose. Their rheological, textural, physicochemical properties and microstructures were evaluated. The concentration of sweeteners was found to have a significant effect on the physicochemical and rheological properties of the formulations. The hardness of marmalades decreased with addition of sweeteners. Herschel–Bulkley model was found to be the best model describing rheological behavior. The consistency index decreased with increasing sweeteners substitution, whereas the flow behavior index showed an increasing trend with the increase of the sweeteners content. Additionally, the microstructure of marmalades with sweetener substitution exhibited a porous structure in the gel network. The increase in sucralose concentration resulted in more surface deformation resulting in weaker gel formation than stevia. Marmalade prepared with 50% stevia substitution was found the best combination and resulted in good sensory properties like marmalade samples containing 500 g sugar
Β-Ketoenamine-linked covalent organic framework for efficient iodine capture
No full textExploring the materials that effectively capture radioactive iodine is crucial in managing nuclear waste produced from nuclear power plants. In this study, a β-ketoenamine-linked covalent organic framework (bCOF) is reported as an effective adsorbent to capture iodine from both vapor and solution. The bCOF’s high porosity and heteroatom-rich skeleton offer notable iodine vapor uptake capacity of up to 2.51g at 75 °C under ambient pressure. Furthermore, after five consecutive adsorption-desorption cycles, the bCOF demonstrates high reusability performance with significant iodine vapor capacity retention. The adsorption mechanism was also investigated using various ex situ structural characterization techniques, and these mechanistic studies revealed the existence of a strong chemical interaction between the bCOF and iodine. The bCOF also showed good iodine uptake performance of up to 512 mg in cyclohexane with high removal efficiencies. The bCOF’s performance in adsorbing iodine from both vapor and solution makes it a promising material to be used as an effective adsorbent in capturing radioactive iodine emissions from nuclear power plants
The Markers of the Predictive Dna Test for Canine Hip Dysplasia May Have a Stronger Relationship With Elbow Dysplasia
No full textCanine hip and elbow dysplasias, which are prevalent orthopedic conditions rooted in developmental and hereditary factors are yet to be comprehensively assessed. This study aimed to address this gap by exploring the prognostic significance of five markers linked to canine hip dysplasia using available genome-wide association studies (GWAS) data. The influence of these markers on both hip and elbow dysplasia was examined in dogs exposed to standardized environmental conditions. We made a groundbreaking discovery using custom primers, qPCR assays, and evaluation of fluorescent resonance energy transfer (FRET) probes. Three specific SNPs previously associated with the risk of canine hip dysplasia demonstrated a potentially stronger correlation with elbow dysplasia. Notably, the SNP at nucleotide position 22691322, located near the canine CHST3 gene, displayed significance as a marker in multivariable logistic regression analysis. Surprisingly, none of the initially targeted SNPs showed a direct association with hip dysplasia. The genomic positions of these SNPs reside within a region conserved across mammals. In silico analyses suggested that the relevant variant might be positioned in a region linked to bone and muscle structures. Our findings revealed a remarkable relationship between SNP2 genotypes and methylation patterns, shedding light on the underlying mechanism that partially explains the genotype-phenotype correlation in canine CHST3. These groundbreaking findings offer essential insights for future, more extensive investigations into canine orthopedic health. This research significantly contributes to our understanding of the molecular foundations of hip and elbow dysplasia in dogs by charting a course for advancements in veterinary medicine and the overall well-being of canine companions
Textural, Rheological, Melting Properties, Particle Size Distribution, and Nmr Relaxometry of Cocoa Hazelnut Spread With Inulin-Stevia Addition as Sugar Replacer
No full textThis study investigated the influence of substituting 60, 80, and 100% of the sugar in traditional cocoa hazelnut paste (control) formulation with inulin-stevia (90:10, w/w) mixture on textural and rheological characteristics, melting behavior, water activity (aw), particle size distribution (PSD), and color. Textural, rheological, melting properties, and color of samples were analyzed after 1, 2, and 3 months of storage at 11°C. Nuclear magnetic resonance (NMR) relaxometry experiments were also performed to understand the interaction of new ingredients with oil. Replacement of sugar with inulin-stevia gave darker color, reduced Casson yield stress, and changed the textural parameters and melting profile of the samples depending on the level but did not create a remarkable effect on PSD and Casson plastic viscosity. Increasing inulin-stevia content yielded lower aw and higher T2a values indicating decreased mobility of water. Complete removal of sugar caused low spreadability. The results showed that an 80% replacement level yielded a product with similar textural parameters and fat-melting mouth feeling compared to control sample. Cocoa hazelnut spreads prepared with inulin and stevia showed good textural stability during storage. © 2024 The Authors. Journal of Texture Studies published by Wiley Periodicals LLC
Stabilisation of Linear Waves With Inhomogeneous Neumann Boundary Conditions
No full textWe study linear damped and viscoelastic wave equations evolving on a bounded domain. For both models, we assume that waves are subject to an inhomogeneous Neumann boundary condition on a portion of the domain's boundary. The analysis of these models presents additional interesting features and challenges compared to their homogeneous counterparts. In the present context, energy depends on the boundary trace of velocity. It is not clear in advance how this quantity should be controlled based on the given data, due to regularity issues. However, we establish global existence and also prove uniform stabilisation of solutions with decay rates characterised by the Neumann input. We supplement these results with numerical simulations in which the data do not necessarily satisfy the given assumptions for decay. These simulations provide, at a numerical level, insights into how energy could possibly change in the presence of, for example, improper data