Set Publisher
Not a member yet
1080 research outputs found
Sort by
Phytochemical and Biological Investigations of Different Partitioned Extracts of Ficus heteropleura Blume (Family: Moraceae) Leaves
Full text linkFicus heteropleura Blume is a plant of the Moraceae family with high medicinal value. Therefore, the plant leaves\u27 fractional extracts have been subjected to preliminary screenings for phytoconstituents and pharmacological studies. The phytochemical analysis was done after fractionating the ethanolic extract with n-hexane, chloroform, and hydro-alcohol. Then, the TLC method, DPPH radical scavenging, disc diffusion, membrane stabilization activity, heat-induced hemolysis, human blood clot lysis, and starch-iodine method were performed. The chemical investigation resulted in the identification of glycosides, amides, reducing sugars, flavonoids, phenols, alkaloids, tannins, saponins, gums, and steroids from the different extracts of the leaves of Ficus heteropleura Blume. In the antioxidant assay, hydro-alcoholic, chloroform, and n-hexane extracts at the dose of 100μg/ml produced significant inhibition of 76.11% (IC50 = 46.47 µg/ml), 72.83% (IC50 = 54.72 µg/ml), and 61.83% (IC50 = 77.95 µg/ml), respectively, as compared to the reference standard drug, ascorbic acid, 85.01% (IC50 = 32.22 µg/ml). However, only moderate anti-inflammatory activity was found in hydro-alcoholic extract (IC50 = 4.24 µg/ml). The extract also showed moderate thrombolytic and membrane-stabilizing effects. Hydro-alcoholic extract had antifungal activity against only Candida albicans (11 mm). However, chloroform plant extract exhibited significant antifungal activity against all included fungi. In the anti-diabetic study, significant inhibition of amylase activity was found by the hydro-alcoholic (73.33%) and chloroform (83.3%) extracts, respectively, whereas the n-hexane was found to have moderate activity (35.44%) compared to acarbose. Therefore, before isolation, characterization, and determination of the mechanism of action of the screened pharmacological activities, further investigation is needed
Data Fixing by Data Fitting: Estimating the Unreported Cases During the Early COVID-19 Outbreak in Hubei, China
No full textOn February 13, 2020, the Health Commission of Hubei Province changed the definition of confirmed cases, resulting in a reported daily case number that is significantly larger than on other dates. Such abnormal data points pose a challenge in data fitting and parameter estimation. To address this, we derive a simple formula from the classical Kermack-McKendrick model and introduce a new quantity to capture the number of unreported cases hidden in the data. We then use this new formula to fit the inconsistent data and estimate key epidemic parameters. Based on the reported cumulative case numbers until February 21, 2020, we estimate that the unreported case number in Hubei is 60856 (95% CI: [33513, 91206]), while the unreported case number in Wuhan is estimated as 29374 (95% CI: [18205, 40665]). The peak times in Hubei and Wuhan are February 6, 2020, and February 8, 2020, respectively. The basic reproduction numbers are 2.334 (95% CI: [2.053, 2.711]) for Hubei and 2.189 (95%CI: [1.992, 2.448]) for Wuhan
Analysis of Radar Interferometry Results on the Deposit Territory
Full text linkFor effective and safe development of mining deposits, it is necessary to study the impact of natural and anthropogenic factors on the development of deformation processes, which provides an opportunity to regulate their impact on the rock mass, earth surface and engineering structures. The size of the deposit, geology and production volumes, affects the area of deformation, which can spread over huge areas. Accordingly, regional deformation monitoring is required for such fields. In order to provide high detail coverage of the area, traditional ground-based methods are impractical and costly. More timely and cost-effective for monitoring deformation of large territories is the use of differential radar interferometry.
The results of high-precision geodetic measurements for the period 2019-2021 revealed that more observation points have significant negative values. This indicates a stable process of subsidence of the earth, predominantly. Analysis and interpretation of the obtained results of geodynamic monitoring (high-precision leveling, radar interferometry), allowed to determine that the condition for the formation of vertical and horizontal deformations of the earth\u27s surface is a natural-technogenic factor
Effects of Magnetized, Chelated Iron Foliage Treatments, and Metal Halide Lamps on Plant Water Structure, Water Vapor Dynamics, and Resilience for Legumes under Water Stress
Full text linkA greenhouse study was conducted to determine the effects of foliar applications of magnetized, chelated liquid iron fertilizer for increasing the drought tolerance of two legumes. The study objectives were to determine the drought tolerance effects of four treatments on foliar gas exchange, soil moisture, and plant growth for soybean (Glycine max) and velvet bean (Mucuna pruriens) plants. The plant treatments included applications with chelated liquid iron fertilizer (2.5 and 5%) with a conventional boom sprayer, with and without magnets in the spray lines, and metal halide lamps. Three gas exchange measurements were collected before applying the foliage treatments and after two water stress treatments. A foliage and metal halide lamp treatment deactivated or unlinked nine interconnected gas exchange parameters that are correlated with plant defense activities during water stress conditions. The deactivation of interconnected regulatory gas exchange functions improved metabolic efficiency, reduced stress levels, and boosted plant resilience to abiotic stressors. Also, the study findings suggest that the study treatments maintained or increased the level of biologically structured water in plant tissues and vascular systems
Some Results on Neutrosophic I-Statistically Convergence
Full text linkThis paper introduces the neutrosophic -statistical convergent difference sequence spaces defined through a modulus function. Additionally, we establish new topological spaces and examine various topological properties within these neutrosophic -statistical convergent difference sequence spaces
Several Derivative Formulas of Two Exponential Functions and Real Power of Hyperbolic Secant Function with a Generalization of a Formula for Specific Partial Bell Polynomials
Full text linkIn the paper, by virtue of some identities for the partial Bell polynomials and with the aid of the Faá di Bruno formula, the author presents several derivative formulas of two exponential functions and the real power of the hyperbolic secant function, and generalizes a formula for specific partial Bell polynomials
Cultural Heritage Environments: Monitoring Strategy for Preventive Conservation of Cultural Assets and Human Health Protection
Full text linkObjects of historic artistic value, conserved in indoor deposits or exhibited inside museum halls, are strongly influenced by the environmental parameters, as temperature, relative humidity and light quality. Environmental parameters directly impact the structural integrity of constitutive materials and promote microbial colonization on artwork surfaces, leading to biodeterioration. In cultural heritage dedicated environments (CHE), the microbial load may exist both on art works surface and in the environmental aerosol (bioaerosol), maintaining a unique balance.
In this study, through a multi-phasic approach the presence of bacteria and fungal colonies in the aerosol and artifacts surface, of an exposure hall, have been investigated. This study defined specific, non-invasive procedures to sample microbial colonies, spread both on artworks surface and in the aerosol of dedicated indoor environments.
Results from morphological analysis (microscopy, in vitro culture) and molecular investigation (microbial genomic DNA), provided useful information on the composition of the microbial consortia, allowing a complete understanding. Microorganisms, in addition to inducing artifacts biodeterioration are able to produce and release, in the aerosol (bioaerosol) of surrounding environment, biological particles and molecules (spores, cellular debris, toxins and allergens), potentially dangerous for the health of operators and visitors.
The complete understanding of the consortia is peculiar to counteract the microbial colonization, also performing green strategies
Assessing the Efficacy of Natural Pet Products in Protecting Gastric Cells and Reducing Cytotoxicity under Hyperacidity Conditions: An In Vitro Study
No full textGastritis in pets necessitates effective acid suppression for successful treatment. However, the synergistic potential of antacid salts within natural feed products remains underexplored. In this in vitro study, we aimed to compare six supplements comprising natural ingredients for their ability to safeguard gastric cells and mitigate cytotoxicity under hyperacidity conditions. While Product 1 showed ineffectiveness in cell protection, Products 2, 3, 4, and 5 exhibited varying degrees of reversal of hyperacidity-induced cytotoxicity. Notably, Product 6 demonstrated superior efficacy in shielding gastric cells from acidic pH-induced cytotoxicity, displaying a dose-dependent response. These findings highlight the potential of natural supplements, particularly Product 6, as promising candidates for mitigating gastritis-related conditions in pets. Further research, including in vivo studies, is warranted to validate these observations and explore their clinical applicability
Application and Optimization of Rheological Mathematical Models in Preparation and Injection Process of Polymer Flooding
No full textThe impact of shear on the properties of polymer solutions is not fully accounted for in the simulation of conventional rheological models. To optimize the application of these mathematical models, the shear rheological characteristics of polyacrylamide at various concentrations were investigated under different shear rates and shear modes. The results indicate that pseudoplastic fluid polymers exhibit two distinct rheological characteristics within their "shear thinning" rate range. The critical shear rate at this threshold signifies the point at which shear stress begins to disrupt the structure of the polymer solution, resulting in a rheological curve that transitions from high to low shear rates without reverting back to a low-to-high state. The concentration of the solution has minimal effect on the critical shear rate of the polymer, which is primarily determined by the inherent properties of the polymer itself. The application of rheological models during preparation and injection processes can elucidate the effects of shear on polymers by analyzing changes in apparent viscosity. Furthermore, the rheological model following supercritical shear rates requires modifications to the consistency coefficient (K) and flow index (n) based on shear rheological data obtained from high to low shear rates
Enhancement of Mechanical Properties in Non-Lethal Projectile Holders through High-Density Polyethylene and Alumina Nanocomposites
Full text linkThis research looks into how to make and describe non-lethal projectile supports out of high-density polyethylene (HDPE) nanocomposites that are strengthened with alumina. This innovative approach enhances the material’s mechanical properties and usability in security applications, significantly advancing over traditional materials. By integrating alumina nanoparticles, we improve the composite’s strength and durability, which is critical for the reliability of non-lethal projectiles. Our findings contribute to materials science by providing a sustainable, efficient, and effective alternative for law enforcement and personal safety equipment