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Effect of Soy Isoflavones Supplementation on Adiponectin Levels in Postmenopausal Women: A Meta-Analysis
Get PDFDecreased adiponectin levels has been demonstrated in postmenopausal (PMP) women. Soy isoflavones, as an herbal product have been shown to increase adiponectin level but the results are inconclusive and inconsistent. The present study reassessed the data on the impact of soy isoflavones supplementation on adiponectin levels in PMP women through a meta-analysis. A systematic search was performed in the databases of PubMed, Web of science, Scopus and the Cochrane library. The literature search identified 830 studies with duplicates. Out of those, 80 were screened for title and abstract and 12 articles were ultimately selected for the analysis. Meta-regression and subgroup analyses, based on the moderator variables such as treatment duration, dose of soy isoflavones and BMI were performed. The quality of the studies was evaluated using the Grading of Recommendation Assessment, Development and Evaluation (GRADE) approach. The results revealed that soy isoflavones supplementation significantly increased the circulating level of adiponectin in PMP women (SMD: 0.36 µg/mL; 95% CI (0.05 to 0.66); P= 0.02). No publication bias was observed using Begg\u27s (P = 0.38) and Egger\u27s (P = 0.07) tests. Sensitivity analysis indicated the results were completely powerful and stable. Moreover, Meta-regression and subgroup analyses indicated a significant increase of adiponectin levels in subgroups of dose > 50 mg and treatment duration less or equal 3 months. Our findings showed significantly increase in adiponectin levels after isoflavones-supplemented soy consumption in postmenopausal women, who received dose > 50 mg of soy isoflavones in treatment duration ≤ 3 months
Effect of Biofertilizer Addition on Nitrous Oxide Emission
Get PDFApplication of nitrogen fixing biofertilizer, such as Azotobacter, has a potential for reducing nitrous oxide(N2O) emission. The aim of this study was to examine the effect of nitrogen fixing biofertilizer addition to common practices of urea and fresh cattle manure usages for maize (Zea mays L.) growing on N2O emission. The field experiment was conducted at GunungKidul, Yogyakarta, Indonesia. The treatments were addition of fresh cattle manure (M), fresh cattle manure added with nitrogen fixing biofertilizer (MB), urea (U), urea added with nitrogen fixing biofertilizer (UB), and control (no N fertilizer added). Nitrogen contents of the added urea and fresh cattle manure were adjusted to be equal. Urea and fresh cattle manure were given three times throughout the experiment period, i.e. 12, 30, and 48 days after planting (DAP). Urea was given at a rate of 44, 29, and 15 kg.ha-1, respectively while fresh cattle manure was given at a rate of 6000, 4000, and 2000 kg.ha-1, respectively. The emitted N2O was collected using a closed-chamber method at 24, 42, 60, and 72 DAP and were determined using Gas Chromatograph. Soil properties including available N (NH4+-N and NO3–-N) and organic C contents were also analyzed. On the harvesting time, the harvest index and the grain yield were determined. Biofertilizer addition influence decomposition process of cattle manure and urea that led to mineralization and nitrification of residual organic matterand hence to cause soil NH4+N in the order concentration of M treatment > MB > U > UB>C, and soil NO3–-N of MB treatment > M > U > UB>C. Reduction of NO3–N was resulted in the highest N2O emission of M >U>MB>UB>C(P < 0.01). The grain yield, and harvest index of maize wereresulted in the order value of MB> UB > U > M>C treatments.Available mineral N and soil organic C contents strongly affected N2O emission (P < 0.01).The results suggested that biofertilizer addition to common agricultural practices reduce N2O emission and simultaneusly increased grain yield, and harvest index of maize
The Suitability of Seashell, Animal Bone and Sodium Carbonate as Energizers in Case Carburization of Mild Steel
Get PDFThis work examines the suitability of using seashell (Oyster shell), animal bone and Na2CO3 materials as energizers for case hardening of mild steel. A carburizer consisting of charcoal was used for research with sea shell, animal bone and Na2CO3 as energizers. Samples were carburized in fabricated rectangular stainless steel boxes using different percentages of energizers (10, 20, 30, 40, and 50%) respectively. The samples were covered completely in each of the boxes with the mixture of carburizer and energizer placed in the chamber of the furnace. The process was carried out at carburizing temperature of 9500C, soaked for 4, 6, and 8hours and quenched in oil. Twenty samples were further tempered at 2000C for 1hour to relieve the stress built up during quenching. Hardness test, chemical analysis and impact test were carried out on the samples. The hardness values of the carburized mild steel were measured with a micro hardness tester. The results of the study showed that hardness values of the untempered mild steel samples were slightly improved than the tempered samples at carburizing temperature of 9500C and carburizing time of 4, 6 and 8hours. The Impact results revealed that samples carburized at 9500C in seashell energizer for 8hours have the highest impact values of 184 Joules for the tempered samples which are higher than the untempered samples due to increase in toughness resulting from tempering. The results also showed that seashell and animal bones are potential energizers in case carburization of mild steel
ZIF-Derived CuPt@Ag as Catalyst for Hydrogen Evolution Reaction
Get PDFIn this study, ZIF-Cu and ZIF-Pt were synthesized from 2-methyl imidazole with Cu and Pt salts in the methanol medium. The synthesized ZIFs were annealed to produce a CuPt nanocatalyst in the tube furnace. The Cu: Pt (3:1) nanocatalyst slurry was deposited on silver deposited carbon rod electrode (CE). The hydrogen evolution reaction (HER) activities for the catalyst were measured in a 1 M KOH solution by using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The morphological structure and composition of CuPt@Ag have been studied by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDX). It was observed that the prepared electrode surface had not only a homogeneous and porous structure but also nano-sized particles distributed on the surface. It has been observed that the current is increased from 5.22 mA cm-2 to 25.80 mA cm-2 under -1.55 V potential at CuPt@Ag electrode. The high current density shows that HER efficiency increases on the prepared catalyst
Effect of Dexmedetomidine-Induced Sleep Balance Treatment on the Chronic Refractory Primary Insomnia Patients
Get PDFAim:To pilot study the therapeutic effect of dexmedetomidine-induced sleep balance treatment (DISBT) on the chronic refractory primary insomnia patients.
Methods:Forty-two patients with chronic refractory primary insomnia were randomly divided into two groups by random number table. Patients in DISBT group were given DISBT for 3 days, while patients in the control group were given conventional treatment for 3 day. Pittsburgh sleep quality index (PSQI), the hyperarousal scale (HAS), and Hamilton anxiety scale (HAMA) were evaluated and compared between the pre-treatment and post-1-week-treatment. Sleep architecture and electroencephalogram (EEG) spectrum were also recorded and compared pre-treatment and post-treatment.
Results:The scores of PSQI and HAMA in both groups after treatment were lower than those before treatment (P < 0.05), DISBT group-reduced degree were higher than those of the control group (P < 0.05). Sleep architecture of Stage 2 sleep proportion, EEG spectrum beta, and gamma relative power value in DISBT group were lower than those before treatment (P < 0.05), Stage 3 sleep proportion and delta relative power value were higher than those before treatment (P < 0.05); Sleep architecture of Stage 2 sleep proportion,beta, and gamma relative power value in control group were higher than those before treatment (P < 0.05); rapid eye movement sleep, Stage 3 sleep proportion, and delta relative power value were lower than those before treatment (P < 0.05). The total scores of the hyperarousal scale (HAS) in both groups after treatment were lower than those before treatment (P < 0.05), DISBT group-reduced degree were higher than those of the control group (P < 0.05), the extreme score, introspectiveness score, react score of HAS in control group after treatment had no statistical significance compared to those before treatment (P > 0.05), the extreme score, introspectiveness score, react score of HAS in DISBT group after treatment were lower than those before treatment (P < 0.05).
Conclusion:DISBT effectively reduced the insomnia patient cortex hyperarousal level, corrected disorder of sleep-awakening pathways and easedup insomnia symptom. It is an effective method for chronic refractory primary insomnia
Antimicrobial Activity Derivatives 2H-pirano[2,3-c]piridines against Pathogens of Intestinal Yersiniosis
Get PDFBackground: An important aspect in the treatment of patients with intestinal yersiniosis is the administration of effective antibiotic therapy. Performed research aimed to determine the spectrum and level of antimicrobial activity of 2H-pyrano[2,3- c]pyridine derivatives on the museum and clinical strains of gram-negative microorganisms Yersinia enterocolitica.
Methodology: The object of the study was 28 synthetic derivatives of 2H-pyrano[2,3- c]pyridine. The compounds were studied according to their chemical structure. We used the method of serial dilutions in Muller-Hinton liquid nutrient medium with a museum’s and clinical strains of Y.enterocolitica.
Results: Studies indicate the promise of further study of the properties of 2H- pyrono[2,3-c]pyridine to create an effective antimicrobial medicine. According to the results of studies on action of antimicrobial compounds synthesized on the basis of 2H-pyrano[2,3-с]pyridine derivatives, it was found that the MIC of compounds for all Y. enterocolitica strains was 100.0 μg/ml. The MBCC of most cultures of Yersinia (72.3 %) was 200.0 μg/ml. Compound 2{3} had a pronounced antiyersiniotic activity, the inhibitory effect of which was manifested at a concentration of 25.0 μg/ml. Retarding the growth of most Yersinia strains (95.3%) with a MIC of 50.0 μg/ml, the MIC of compounds ranged from 50.0 to 200.0 μg/ml. After statistical data processing, pyridine derivatives (compounds 2{3} and 3{5}) were identified, possessing an effective bacteriostatic and bactericidal effect on Y. enterocolitica strains.
Conclusions: The results of the research showed a high antimicrobial activity of 2H- pyrano[2,3-c]pyridine derivatives. The highest activity against Y. enterocolitica was found for 2-N2-arylimino-5-hydroxy-methyl-8-methyl-2H-pyrano[2,3-c]pyridine-3-N1- aricarboxamide derivatives
Heavy Protein Alteration under the Effects of Lead Acetate in Bactrocera cucurbitae
Get PDFLead is supposed to be an important poisonous waste which could contaminate the environment, therefore, insects could be influenced easily by the lead., Bactrocera cucurbitae was studied at 48 hours post treatment, under the effects of lead acetate, in different concentrations of 0.125 mg., 0.25 mg., 0.5 mg, 1.0 mg and 2.0 mg. It was observed that under the effects of lead abnormalities and deformity were developed in the larvae of flies. Thus these flies could present a useful module for the quick transmission of the environmental hazards due to lead contamination, which exerts a specific physiological and morphological effect on these flies
Physico-Chemical Analysis of Solid Aerosols Generated from Different Industries of Faisalabad
Get PDFThe physical, chemical and electrical characteristics of industrial aerosols generated from different industries of Faisalabad were investigated not only to improve the industrial setup efficiency but also to reduce the environment pollution generated due to these industries. XRPD technique was employed to study these samples which showed the presence of illite, Quartz, calcite, dolomite, gypsum and chlorite as major phases. The values of resistivity of solid aerosols are in high range (0.07×107 to 4.0×109 ?m) conversely the electrical conductivities are in lower range (0.21-13.30Mho), may be due to high components of Fe2O3 and CaO. Coal fly ash and foundry aerosols do precipitate well in the electrostatic precipitator given their operational temperature and moisture content so it is recommended that by changing the temperature and moisture content of the precipitator its cleaning action and hence the industrial efficiency may be improved. The most of the solid aerosols are alkaline therefore acidic rain probability in near future is completely ruled out. 80% basic (Dark color), 20% acidic (light color) of particulate matter confirms our experimental findings. The SEM analysis of particulate matter showed the presence of a variety of patches but confirms the dominance of industrial cum transportational aerosols interlocking and soot particles. Finally comprehensive research and administrative based solution to tackle the issue without affecting the development process is suggested
Study of Wind Speed and Wind Potential at Kagbeni, Thini and Palpa in Nepal
Get PDFThe primary objective of this paper is to study and analyze the wind characteristics and power potential at the three different places in Nepal. One year of wind speed data measured at 10 m and 20m height above ground level, provided by the Department of Alternative Energy Promotion Center, have been analyzed in this study. Direct use of data including the mathematics of probability and statistics has been applied to compute the wind power potential of the proposed sites with the occurrence of effective wind speed between cut-in and cut-out speed. The diurnal wind speed variation analysis of the three different sites showed that higher wind speed occurred during the daytime and reached a maximum at 3 PM whereas the lowest wind speed occurred after midnight and achieved a minimum at 7 AM to 8 AM. On basis of wind energy potential, Kagbeni has an annual potential energy of 3.98MWhr/m2 at 10m height and 4.82MWhr/m2 at 20m height while Palpa has the potential of 0.27MWhr/m2 and 0.36MWhr/m2 at the two heights with wind speed more or equal to 3m/s. Similarly, Thini has potential of 2.4MWhr/m2 and 2.9MWhr/m2 at 10m and 20m height on the limit of above wind speed. On the monthly basis, Kagbeni and Thini have the highest average wind speed in June whereas Palpa has in March and April. Likewise the highest value of wind speed at Kagbeni, Palpa and Thani are found as 22.53m/s and 21.75m/s; 17.66m/s and 17.11m/s, and 17.9m/s and 7.3m/s in April and March at heights of 10m and 20m respectively
Dreams, Shrines and Mystic Sufi in Palestine
No full textThis paper describes common Sufi beliefs regarding dreams and shrines in Palestine during the 20th century. These beliefs developed during joint and private seasonal visits (ziara). Gaining insight into the sociology of the Sufi cult of saints can enrich our understanding of similar cults in other places and shed light on the reasons for their absence in other societies. The research examines the phenomenon of true dreams at saints’ shrines, and explores the historical and contemporary scope of dream pilgrimages to these shrines.
Ceremonies that involve visiting saints’ shrines have encouraged socio-cultural and psychological-therapeutic dependence of the pilgrims with regard to these shrines. This dependence relationship is deeply rooted in their collective psyche and reinforced and legitimized through Palestinian folklore.
This paper is based on primary and secondary sources, interviews with Sufi and people who have been active in participating in these rituals, as well as archival and documentary material, a review of published and unpublished materials, books, and scientific journals