Set Publisher
Not a member yet
1080 research outputs found
Sort by
Impact of Chromium Addition on the UTS and ETF of Aluminium Alloy AA6061 Chips Based Composite
Get PDFAluminium matrix composite has been increasingly developed due to the impressive performances demonstrated, mechanically and physically. The related properties were enhanced with the addition of reinforcing materials and this tailor-made composite can be used in the area of automotive, aerospace and military. In this study, the matrix composite was developed directly from aluminium chips without remelting through a series of hot press forging operations. This process involved heating the aluminium chip mixtures with 1 to 8 wt% chromium content above the recrystallization temperature. Then, the uniaxial force was subsequently applied onto the composite. For performance measures, the hot pressed composites were tested for the ultimate tensile strength (UTS) and elongation to failure (ETF). The composite with 2 wt % of chromium exhibits significant improvement compared to other samples, with the UTS and ETF reached to 215.37 MPa and 30.65% respectively. This sample exceeds the minimum stress and strain of stock aluminium AA6061-T4. Furthermore, the addition of chromium beyond 2 wt % would generally cause reduction of the mechanical properties of the composite
Evaluation of Weight Reducing Effect of Evening Primrose Oil
Get PDFWeight reducing effect of Evening primrose oil in healthy rabbits was assessed following administration of EPO for 60 days in the doses of 90, 180 and 360 ul/Kg. Reduction in weight might be due to significant decrease in cholesterol, triglycerides, LDL-C, blood glucose and increase in HDL-C
Phenolic Contents and Antioxidants Activities in Jamman Fruit (Eugenia jambolana) Products
Get PDFIn this study, total phenolic contents and antioxidant activity were determined in various products made from two cultivars of jamman fruit (Eugenia jambolana) i.e. improved (V1) and indigenous (V2). Five products were made from each cultivar such as jam, squash, ready-to-drink juice, pulp powder and seed powder. Fruit cultivars were endogenous to the typical region of Sindh-Pakistan. Total phenolic contents were analyzed by Folin-Ciocalteu colorimetric method, whereas, the total antioxidant activity was analyzed by using the 2, 2-diphenil-1-picrylhydrazyl radical scavenging capacity (DPPH) assays. The highest total phenolic contents and antioxidants were observed in freeze dried seed powder while the lowest contents were found in squash
Potential Effect of Medicinal Plants on the Prevention of Gastric Ulcer: Mechanism of Actions
Get PDFMedicinal plants have been widely studied to identify plant-based anti-gastric ulcer medicines. The mechanism of gastroprotective action is important to discover the potential lead compounds for drug development. All relevant articles between 2011 and 2021 focusing on Malaysian plants were collected and analyzed to understand the underlying pathways. Keywords include peptic ulcer, gastric ulcer, NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), Helicobacterpylori, medicinal plant, gastroprotection, antiulcer, acid secretion, cytoprotective, and digestion processes were applied in the search engines. Twenty-two of the plants had been reported based on the collected data. The review concludes that Malaysian plants could protect the gastric wall against necrotizing agents like ethanol and NSAIDs. This is mainly due to four critical defensive mechanisms: cytoprotective barriers, regulation of heat-shock protein 70 (HSP70) and pro-apoptotic protein (BAX), gastric acid secretion, and antioxidant capability. The mechanisms have been illustrated in the schematic diagrams for better understanding
A Generalized Review on Extraction of Biomolecules
Get PDFNature has given us a wide range of biological compounds that can be utilized to help combat health problems, but sometimes with over-processing, these advantages are diminished or lost. Food and pharmaceutical companies have developed a range of new approaches to harness and retain the naturally occurring diversity and quality of bioactive compounds efficiently and effectively. Pharmaceutically important plant products have been known for millennia; they have been used in crude and unrefined forms. One of the best ways to pick the best plant bioactive is through genetic engineering, omics, and plant tissue culture. Many laboratories routinely screen plant species for bioactive compounds to discover new ones. All extraction methods depend on the researcher\u27s preference and what exactly the research entails. Successful extraction begins with the careful selection and preparation of plant samples and thorough knowledge and review of the appropriate literature. Here we have attempted to describe the different stages and methods of extraction from the medicinal plants. From the review, it can be concluded that no universal extraction method is ideal and that each extraction procedure is unique
An Overview of the Oscillating Water Column (OWC) Technologies: Issues and Challenges
Get PDFThere is a vast amount of energy available in ocean waves which can contribute to provide the electricity supply specially for countries surrounded by the ocean. This paper provides background knowledge in different techniques to harness the kinetic and potential energy in wave power along with an overview of the recent developments in Oscillating Water Columns Wave Energy Converters. The main purpose of this study is to provide a thorough review on the current state of the technology and methods in Wave Energy Converters and to help scientists to find the future potential and gaps in this area. Moreover, significant research opportunities are identified based on the literature review of the existing research studies, and research problems to be addressed are presented and can be used as tool for the future research in this area
Plant Products as Biocides for Conservation of Cultural Asset Sustainable for Human and Environmental Health
Get PDFIn the last decades plants products are increasingly used also in defining innovative procedures for sustainable conservation of cultural heritage. Particularly, essential oils or hydro-alcoholic extracts have been fruitful applied to contrast microbial colonization on organic and inorganic artworks or insect infestation (Anobidae) having regard to the repellent action.
In this paper, extracts from Asteraceae and Lamiaceae plant families are utilized to counteract widespread microbial colonization (bacteria, cyanobacteria, fungi) due to their antimicrobial activity. In order to define the adequate concentration correlating it to microbial species detected, the antimicrobial activity of natural products is preliminary in vitro assayed by Agar Disc and Well Plate Diffusion methods. Moreover, an integrated approach based on morphological analysis (optical, scanning and confocal electron microscopy), in vitro cultures (Nutrient or Sabouraud agar) and molecular investigation (genomic microbial DNA extraction, sequencing and sequence analysis) are routinely performed for the identification of largest number of microbial taxa.
Besides, to enhance the antimicrobial activity different protocols have been performed, such as for Thymus vulgaris products directly applied on wooden sculpture surface as hydro-alcoholic extract, followed by exposure, in a dedicated chamber, to the volatile compound of the corresponding Essential Oil. In other case studies, the exposure to volatile compounds of Crithmum maritmum, Inula critmoides, Thymus vulgaris and Origanum vulgare essential oils was performed under controlled vacuum conditions, comparing the effects to environmental condition exposure. These studies confirm the possible use of plant extracts in replacing synthetic chemical biocides, in full respect of human health and environment sustainability
Cellular Trafficking and Subcellular Interactions of Cationic Gene Delivery Nanomaterials
Get PDFVarious cationic nanobiomaterials have been widely used as gene delivery nanosystems (GDNSs) in vitro and in vivo. Various cellular machineries are involved in trafficking of GDNSs, whose surface functional moieties and architectural properties confer great potential to interact with cell membranes and subcellular biomolecules. It appears such intrinsic inadvertent biological functionalities may impact the outcome of the biomedical applications of these nanobiomaterials. Various advanced materials used as GDNSs may display selective phenotypic effects in target cells/tissues as a result of initiation of various signaling pathways perhaps due to its cellular interactions with plasma cell membranes and/or intracellular compartments including genetic materials. Thus, better understanding about cellular/molecular impacts of GDNSs may maximize their clinical outcomes and accordingly minimize their inevitable undesired consequences. The main focus of this review is based on the cellular trafficking and interactions of cationic gene delivery nanobiomaterials with target cells or subcellular compartments
Aflatoxins B1 and B2 Contamination of Peanut and Peanut Products and Subsequent Microwave Detoxification
Get PDFThe effectiveness of microwave heating has been evaluated for the detoxification of aflatoxins contaminated peanut and peanut products. The products comprise of various confectionery such as peanut brittle toffee, peanut brittle slabs of sugar and jaggery, roasted and salted peanut and peanut butter which were highly contaminated with aflatoxins B1 ranging from 5 to 183µg/kg and aflatoxin B2 ranging from 7 to 46.7µg/kg. The level of aflatoxins was determined and subsequently products were treated to microwave heating, which resulted in the reduction of aflatoxins content. The microwave cooking resulted in 50 to 60 % reduction in the levels of aflatoxins B1, while B2 was reduced to non-detectable limits
Behavioral and Memory Boosting Effects of Intellan and Cyanocobalamin in Mice
Get PDFThe aim of this study was to compare the effect of selected drugs, Intellan and cyanocobalamin on some aspects of animal behavior, like effect on memory, depression, gross behavior and exploratory activity. Results of present investigations reveals cyanocobalamin to be a good memory enhancer and intellan also showed memory boosting effects in addition to anti-anxiety activity which affects overall performance.