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C. R. Chimie 20 (2017) 593e594
lable at ScienceDirectContents lists avaiComptes Rendus Chimie
www.sciencedirect.comNew pluses in carbanion chemistry*Foreword
The diversity of the results presented during the latest
International Symposium on Carbanions Chemistry (ISCC-
XI) held in Rouen, France from 17 to 21 July 2016 deserves
to be emphasized, and this thematic issue reflects the broad
variety of the selected lectures. Works from inorganic to
organic synthesis, from spectroscopy to computational
chemistry, from methodology to total synthesis were
encompassed, and the subsequent discussions were often
long and lively.We are looking forward to the opportunities
that the ISCC-XII will provide and warmly thank Prof.
Armen Zakarian for organizing the next exciting edition in
Santa Barbara (California, USA) in 2019!
The cross-fertilization brought by interdisciplinary ap-
proaches does not need advocacy anymore and when
chemists, spectroscopists, and theoreticians all lean around
a cradle sheltering a newborn problem, one can expect the
best! ISCC-XI and this issue of Comptes rendus Chimie
demonstrate that regularly gathering scientists dealing
with carbanions is remarkably fruitful.
Several participants appreciated what they felt like a
friendly and cooperative atmosphere during ISCC-XI. It is
interesting, a posteriori, to figure out the origins of this* A thematic issue of the Comptes rendus Chimie on the occasion of the
11th International Symposium on Carbanions Chemistry (ISCC-XI), July
2016, Rouen (France)
http://dx.doi.org/10.1016/j.crci.2017.05.002
1631-0748/© 2017 Published by Elsevier Masson SAS on behalf of Académie desform of serenity. First, this was a relatively small meeting
(about 100 attendees). More generally, serenity in science
seems to call for time, time given to creativity to establish
on firm and credible grounds its findings, scope and ad-
vances. It is not always easy to remain outside of the gusts
of scientific fashion. Being less “topical” often means being
not so attractive to general public and thus not perceived as
relevant by the best students. It also means that it is more
difficult to justify in front of non-scientists and thus to
finance. We still believe that science grows even better and
stronger when intense stress and fierce competition are
avoided. Right now, the chemistry of carbanions is probably
more like a peaceful swell, bringing a regular and in-depth
flow of information to its sailors. Let us wisely enjoy the
calm that reigns offshore.
Jacques Maddaluno*, Michael De Paolis, Xavier Franck,
Dominique Cahard
Laboratoire COBRA (UMR 6014 & FR 3038),
CNRS / Universite de Rouen / INSA de Rouen, 76821
Mont-Saint-Aignan cedex, France
 Corresponding author.
E-mail address: jmaddalu@crihan.fr (J. Maddaluno)sciences.
Nouveaux plus en chimie des carbanions**
Avant-propos
La diversite des resultats presentes lors du dernier
Symposium international sur la chimie des carbanions
(ISCC-XI), qui s'est tenu a Rouen (France) du 17 au 21
juillet 2016, merite d'être soulignee, et ce numero
thematique reflete la grande variete des conferences qui
ont ete presentees. Des travaux allant de synthese
inorganique a la synthese organique, de la spectroscopie
a la chimie computationnelle, de la methodologie a la
synthese totale ont ete mis en avant par des
presentateurs enthousiastes, et les discussions con-
secutives ont souvent ete longues et fournies. La
communaute attend donc avec impatience la tenue de
l'ISCC-XII, et nous remercions chaleureusement le pro-
fesseur Armen Zakarian pour l'organisation de la pro-
chaine edition a Santa Barbara (Californie, Etats-Unis) en
2019. Elle promet d'être passionnante!
Si la plus-value de l'approche interdisciplinaire en
general n'a plus besoin d'être demontree, il est aussi
devenu clair que, lorsqu'un chimiste, un spectroscopiste
et un theoricien se penchent ensemble sur le berceau
d'un nouveau probleme, on peut s'attendre a un feu
d'artifice d'idees nouvelles ! La collection d'articles de ce
numero special montre en tout cas que rassembler de
façon reguliere les scientifiques travaillant sur ces
especes est tres fructueux.
Plusieurs participants nous ont fait remarquer que
l'atmosphere de l'ISCC-XI leur avait semble particuliere-
ment amicale et cooperative. Si serenite il y a eu, elle le
doit surement a la taille modeste du congres (une cen-
taine de participants). De façon plus generale, la serenite
en science nous semble associee au temps, temps accorde
a la recherche pour etablir les conclusions, la portee et les
avancees de ses resultats sur des bases a la fois fermes et
credibles. Il n'est pas toujours facile de rester en dehors
des bourrasques de la mode scientifique. Être moins en
vue signifie souvent n'être pas tres attrayant pour le
grand public, et donc peu attractif envers les meilleurs
etudiants. Mais cela signifie aussi avoir plus de peine a
justifier ses travaux aux yeux du public et donc de
difficulte a les financer. Nous ne croyons pourtant pas que
la qualite de la science soit correlee au stress et a la
ferocite de la concurrence entre ses chercheurs. A l'heure
actuelle, la chimie des carbanions se vit plus comme une
houle egale parcourant l'ocean de la connaissance,
apportant une information solide et reguliere a ses ma-
rins. Sachons sagement profiter du calme qui regne au
large.
Jacques Maddaluno*, Michael De Paolis, Xavier Franck,
Dominique Cahard
Laboratoire COBRA (UMR 6014 & FR 3038),
CNRS / Universite de Rouen / INSA de Rouen, 76821
Mont-Saint-Aignan cedex, France
* Auteur correspondant.
Courriel : jmaddalu@crihan.fr (J. Maddaluno)
Editorial / C. R. Chimie 20 (2017) 593e594594** Un numero thematiques des Comptes rendus Chimie a l'occasion du
11e Symposium international sur la chimie des carbanions (ISCC-XI),
Juillet 2016, Rouen (France)


New pluses in carbanion chemistry

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Innovative methodology for developing a bone grafting composite biomaterial starting from the seashell of <i>Rapana thomasiana</i>

An exhaustive conformational analysis of <i>N</i>-formyl-l-tyrosinamide using a genetic algorithm for multimodal search