Australasian Medical Journal
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Malignant melanoma of soft parts with osteoclast-rich giant cells: A rare tumor of the jejunum
Get PDFMalignant melanoma of soft parts (MMSP), first described by Franz M. Enzinger, is a rare tumor of unknown cell origin. We describe a case of a 45-year-old male who presented with a 1-year history of abdominal pain, weakness, and anaemia. Computerized tomography enteroclysis showed a mass in the jejunum that was suggestive of a gastrointestinal stromal tumor. An ulceroinfiltrative lesion measuring 6.5 x 4 x 2 cm was identified. Microscopy revealed typical features of MMSP with numerous osteoclasts-like giant cells. The diverse histomorphology and immunohistochemical characteristics of this case involving a rare tumor at a rare site is presented.
Validation of the Thai QOL-AD version in Alzheimer's patients and caregivers
Get PDFBackgroundQuality of life (QOL) plays an important role in determining the improvement of patient care in Alzheimer’s disease. The simple and easily used Thai instrument for measuring QOL is still limited. AimsThis study aimed to translate the Quality of Life–Alzheimer’s Disease (QOL-AD) scale original version into a Thai version and test its psychometric properties. MethodA Thai version of QOL-AD was translated following the sequential method. The validation was tested in 136 pairs of patients and their caregivers. Mild to moderate Alzheimer’s patients were recruited from outpatient clinics at Chiang Mai Neurological Hospital and Chiang Mai Psychiatry Hospital from April to September 2012. Internal consistency, factor analysis, and construct validity were evaluated. ResultsInternal consistency of Thai QOL-AD version was good for both patients (0.82) and caregivers (0.82). The results of factor analysis indicated three factors (physical and psychological well-being, social well-being, and close interpersonal relationships) in the patient group, while four factors were found (social well-being, functional ability, psychological well-being, and physical well-being) in the caregiver group. The scaling success in the patient group was around 80–83 per cent for convergent validity, and 70–83 per cent for discriminant validity. The caregiver group showed higher scaling success in convergent validity except for the psychological well-being domain. The scaling success of discriminant validity was around 44–83 per cent for caregivers. ConclusionThe findings of the study demonstrate a good reliability of a Thai QOL-AD version for both patient and caregiver groups. Validity, especially in the caregiver group, might need to be re-examined.
Can a cricket ball influence societal change? Exemplifying societal dichotomy in the tolerance of risk
Get PDFAn uncommon cause of ascites; spontaneous rupture of biliary cystadenoma
Get PDFBiliary cystadenomas are cystic hepatic tumors of biliary origin. Cystadenomas are often slow growing benign tumors but always harbor the risk of malignant transformation. Cystadenomas are often asymptomatic but may present with abdominal pain and distension. Though suspected with cross sectional abdominal imaging definitive diagnosis almost always requires histology. Spontaneous rupture of cystadenoma had been reported thrice in medical literature till date, all presenting with peritonitis. We here report a case spontaneous intraperitoneal rupture of biliary cystadenoma presenting as ascites without peritonitis
An unorthodox innervation of the gluteus maximus muscle and other associated variations: A case report
Get PDFKnowledge of peripheral nerve morphology, location, and variation is important for facilitating appropriate diagnosis and intervention. We present a unique case of absence of the inferior gluteal nerve and high division of the sciatic nerve. In this instance, the common peroneal nerve was found piercing the piriformis muscle and emerging distally in the form of two trunks: thin medial and thick lateral. The medial trunk presented an interesting course, supplying the gluteus maximus muscle before joining the lateral trunk to form the common peroneal nerve. Additionally, the arteria nervi ischiadisci was also observed accompanying and supplying the tibial nerve passing inferior to the piriformis. These variations are important for clinicians and surgeons for some radiological diagnoses and surgical procedures in the lower limb
