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The Impact of Consumer Purchase Intention and Halal Brand Equity on Halal-Labeled Instant Noodle Products in Indonesia
Purpose: This research aims to examine the impact of consumer purchase intention and halal brand equity from a halal perspective, namely halal brand image, halal brand perceived quality, halal brand satisfaction, halal brand trust, and halal brand loyalty.
Method: This research employs an online questionnaire to collect data from 210 respondents aged 17 and above who have experience consuming halal-labeled instant noodles in Indonesia. Based on the research objective, it falls under basic research. Based on the research type, it falls under causal research. Based on the research approach, this research is classified as quantitative research. Furthermore, this research aims to elaborate on the relationships between halal brand image, halal brand perceived quality, halal brand satisfaction, halal brand trust, halal brand loyalty, purchase intention, and halal brand equity. The theoretical model with hypothesized relationships was developed and tested using the structural equation modeling procedure in SPSS AMOS.
Result: The findings of this research indicate that halal brand image has a significant and positive influence on halal brand perceived quality, halal brand satisfaction, halal brand trust, halal brand loyalty, and purchase intention. Similarly, halal brand perceived quality, halal brand satisfaction, halal brand trust, and halal brand loyalty have a significant and positive influence on purchase intention. Furthermore, halal brand satisfaction significantly and positively influences halal brand equity, but the relationship between halal brand trust and halal brand equity could not be established
Pola Penggunaan Obat pada Disabilitas Tunanetra: Kajian Naratif
Penggunaan obat merupakan salah satu kesulitan yang dialami oleh disabilitas tunanetra dalam meningkatkan kualitas kesehatannya. Tujuan penulisan artikel ini adalah untuk mengetahui pola penggunaan obat di kalangan penyandang disabilitas tunanetra. Metode yang digunakan dalam penulisan artikel ini adalah literature review. Pencarian artikel dilakukan melalui Google Scholar dan PubMed dengan kata kunci berupa medication problems, drug use, dan visual impairments. Jumlah artikel yang berhasil dikumpulkan sebanyak 292 artikel, namun hanya empat artikel yang termasuk dalam kriteria inklusi. Hasil penelitian menunjukkan bahwa terdapat dua pola penggunaan obat utama yang digunakan oleh disabilitas tunanetra, yaitu mengandalkan bantuan orang lain dengan penglihatan normal dan menerima obat sendiri. Kedua pola ini memberikan bentuk bantuan yang berbeda bagi disabilitas tunanetra untuk dapat menggunakan obat dengan cara yang benar.
The use of drugs is one of the difficulties experienced by the visually impaired in improving the quality of their health. The purpose of this review article is to find out the pattern of drug use among blind people with disabilities. The method used in writing this article is a literature review. Article searches were conducted through Google Scholar and PubMed with keywords such as medication problems, drug use, and visual impairments. The total number of articles found was 292, but only four articles met the inclusion criteria. The results showed that there were two main patterns of drug use for blind people, namely, relying on the help of others with normal vision and receiving the drug itself. These two patterns provide different forms of assistance for the visually impaired to use drugs in the right way
Kajian Continuity of Care Pasien Program Rujuk Balik di Puskesmas Kota Surabaya
Pasien penyakit kronis menjalani transisi pelayanan kesehatan, sehingga kesinambungan perawatan atau continuity of care (CoC) menjadi komitmen antar tenaga kesehatan. CoC diukur dari perspektif pasien berdasarkan pengalaman dalam pelayanan kesehatan terkait kesinambungan informasi, hubungan dan manajerial. Tujuan penelitian adalah melakukan kajian CoC pasien DM tipe 2 dan hipertensi PRB Puskesmas Kota Surabaya dan menggali pengalaman pasien dalam transisi pelayanan kesehatan. Rancangan penelitian adalah mixed methods. Sampel ditentukan secara purposive dengan memperhatikan kriteria penelitian. Pengumpulan data dilakukan dengan menggunakan kuesioner Cuestionario Continuidad Asistencial Entre Niveles de Atencion (CCAENA) dan wawancara semi-terstruktur. Kesinambungan hubungan berada pada tingkat yang tertinggi, dimana hubungan dengan dokter spesialis lebih tinggi (95%) dibandingkan dokter umum (74%). Ketidaksinambungan hubungan terbesar, yaitu tidak bisa berkonsultasi dengan dokter yang sama di Puskesmas (58%). Kesinambungan manajerial terkait koherensi perawatan (91%) dan aksesibilitas (79%). Ketidaksinambungan manajerial terbesar adalah tidak ada koherensi perawatan antara dokter spesialis dan dokter di Puskesmas (85%) serta aksesibilitas saat antri di rumah rakit (48%). Kesinambungan informasi berada pada tingkat paling rendah (73%). Ketidaksinambungan informasi terbesar adalah diskusi antara pasien dan dokter di Puskesmas terkait pengobatan setelah rujukan (37%). Kesimpulan dari penelitian ini adalah ketidaksinambungan dalam transisi perawatan pasien penyakit kronis terbesar adalah pemberian informasi. Apoteker memiliki peran penting untuk meningkatkan pelayanan informasi dan menjamin keselamatan pasien disetiap rantai perawatan.
Transition of healthcare increases the risk of chronic disease patients, therefore continuity of care (CoC) is needed for patient care. CoC measure from the patient's perspective based on experience related to continuity of information, relationships and managerial. The purpose was to study of CoC patients with type 2 diabetes mellitus (T2DM) and hypertension referral program at the Surabaya City Public Health Center and explore patient experiences in transitioning health services. The design is mixed methods. The sample was determined purposively by observe into research criteria. Data collection was using the Cuestionario Continuidad Asistencial Entre Niveles de Atencion (CCAENA) questionnaire and semi-structured interviews. Relation continuity is the highest level, where relationships with specialist are higher (95%) than general prescriber (GP) (74%). The biggest discontinuity is not being able to consult the same GP (58%). Managerial continuity related to coherence of care (91%) and accessibility (79%). The biggest managerial discontinuity is coherence between specialist and GP (85%) and accessibility when queuing at the hospital (48%). Information continuity is the lowest level (73%). The biggest discontinuity is discussion between patients and GP regarding treatment after referral (37%). Conclusion this study is the biggest discontinuity in the transition of care for chronic disease patients is information. Pharmacists have an important role to improve information services and ensure patient safety
Studi In Silico Potensi Metabolit Sekunder Eleutherine palmifolia (L.) Merr. sebagai Inhibitor Protein E6 dan E7 dari Human Papilloma Virus
Abstract—Human Papilloma Virus (HPV), especially variants 16 and 18, are the causative agents of cervicals cancer. The E6 and E7 proteins are known to play a role in the cervical cancer regulation. Dayak onion plants have been widely used by local people as traditional medicine, including in treating cancer. Until now, there is no known compound or scientific evidence related to its activity of Dayak onion plants against HPV. The plant contains flavonoids, alkaloids, naphtoquinone and several types of polyphenols. Several flavonoids and naphtoquinones from other plants are known to have the ability to treat cancer, especially cervical cancer. In this study, we performed in silico screening of the secondary metabolites, especially the flavonoid and naphtoquinone groups, of Dayak onions which might be active against E6 and E7 proteins of HPV16 and 18. The result showed that there were six flavonoids’ compounds and four naphtoquinone compounds which were predicted as candidates to treat cervical cancer. The Pa values of all compounds, including the positive control, the resveratrol, were less than 0.5 which meant that all compounds showed no activity as anticancer. Analysis of physicochemical, pharmacokinetics, and toxicity predictions exhibited that all compounds could be absorbed, distributed, metabolized, and excreted in human body and non-toxic. Among the ten compounds, only 1,4-Naphthoquinone had weaker interaction with E6 and E7 proteins than resveratrol. Ephicatecin gallate had the strongest binding affinity with protein E6 HPV16 (-7,7 kkal.mol-1) and E7 HPV18 (-7,1 kkal.mol-1), whilst rutin was the strongest interaction with E6 HPV16 (-7,8 kkal.mol-1) and E7 HPV18 (-6,2 kkal.mol-1). As a conclusion, the ephicatecin gallate and rutin compounds of BDayak onion could be used as potent candidat to inactivate the E6 and E7 proteins of HPV 16 and HPV18. The two compounds were also predicted had similarity as medicine and were suitable in bioavailability to be applied as agents for cervical cancer therapy.
Keywords: E6 and E7 oncogene proteins, cervical cancer, flavonoid, naphtoquinone, onion dayak
Abstrak—Human Papiloma Virus (HPV) varian tipe 16 dan 18 merupakan salah satu penyebab kanker serviks. Protein E6 dan E7 dari HPV merupakan protein utama yang berperan dalam regulasi kanker servix. Tanaman Bawang Dayak telah banyak digunakan secara tradisional untuk mengatasi kanker. Hingga saat ini belum diketahui senyawa atau pembuktian ilmiah terkait khasiatnya pada tanaman Bawang Dayak. Bawang Dayak mengandung senyawa flavonoid, alkaloid, naphtoquinone dan beberapa tipe polifenol. Beberapa senyawa golongan flavonoid dan naphtoquinone dari tumbuhan lain telah dibuktikan berperan dalam mengatasi kanker, terutama kanker servix. Pada penelitian ini dilakukan skrining secara in silico metabolit sekunder, khususnya golongan flavonoid dan naphtoquinone, dari Bawang Dayak yang berpotensi menghambat protein E6 dan E7 dari HPV16 dan HPV18. Hasil analisis menunjukkan bahwa ada enam senyawa golongan flavonoid dan dan empat senyawa naphtoquinone yang diduga berpotensi sebagai anti kanker serviks. Nilai Pa kurang dari 0,5 untuk semua metabolit sekunder dan kontrol positif, resveratrol tidak menunjukkan aktivitas. Analisis sifat fisikokimia, farmakokinetik dan potensi toksisitas bagi tubuh menunjukkan bahwa semua senyawa teridentifikasi mampu diabsorbsi, didistribusi, dimetabolisme dan diekskresi dari tubuh dan tidak toksik. Interaksi sepuluh metabolit sekunder Bawang Dayak dengan protein E618 dan E716 menunjukkan bahwa hanya 1,4-Naphthoquinone yang berinteraksi lebih lemah dibandingkan resveratrol. Ephicatecin gallate berinteraksi paling kuat dengan protein E6 HPV16 (-7,7 kkal.mol-1) dan E7 HPV18 (-7,1 kkal.mol-1). Rutin berinteraksi paling baik dengan E6 HPV16 (-7,8 kkal.mol-1) dan E7 HPV18 (-6,2 kkal.mol-1). Berdasarkan hasil analisa, dapat disimpulkan bahwa senyawa ephicatecin gallate dan rutin Bawang Dayak berpotensi sebagai kandidat penghambat protein E6 dan E7 dari HPV 16 dan HPV18. Kedua senyawa juga diduga memiliki kesamaan dengan obat dan secara bioavailibilitasnya cocok jika diterapkan sebagai agen terapi kanker serviks.
Kata kunci: bawang dayak, flavonoid, kanker servix, naphtoquinone, protein onkogen E6 dan E
Implementasi Multimedia Software Engineering Methodology Pada Pembuatan Perangkat Promosi Wisata
Abstract—Artikel ini membahas tentang perbedaan antara multimedia interaktif dan non-interaktif. Multimedia non-interaktif ditampilkan dalam format linier dan pengguna tidak dapat berinteraksi dengan kontennya, sedangkan multimedia interaktif memungkinkan pengguna untuk berinteraksi dan mengontrol cara konten ditampilkan. Dalam pembuatan produk multimedia, developer biasanya mengacu pada dua metode, yaitu Software Development Lifecycle (SDLC) dan Multimedia Production Stage (MPS). MSEM (Multimedia Software Engineering Methodology) adalah metode pengembangan perangkat lunak yang didesain untuk membantu dalam pembuatan aplikasi multimedia interaktif atau non-interaktif. Studi ini mengkaji manfaat MSEM pada implementasi produk multimedia dengan mempelajari dampak dan manfaat penggunaan MSEM pada perangkat promosi wisata lokal yang memuat multimedia interaktif dan non-interaktif. Manfaat penelitian ini adalah untuk memberikan masukan pihak developer multimedia untuk menggunakan MSEM dalam merencanakan dan mengembangkan produk multimedia.
Abstrak—This article discusses the difference between interactive and non-interactive multimedia. Non-interactive multimedia is displayed in a linear format and users cannot interact with its content, while interactive multimedia allows users to interact and control the way content is displayed. In the creation of multimedia products, developers usually refer to two methods, the Software Development Lifecycle (SDLC) and the Multimedia Production Stage (MPS). MSEM (Multimedia Software Engineering Methodology) is a software development method designed to assist in the creation of interactive or non-interactive multimedia applications. This study examines the benefits of MSEM in multimedia product implementation by studying the impact and benefits of using MSEM in promoting local tourism products containing interactive and non-interactive multimedia. The purpose of this research is to provide input for multimedia developers to use MSEM in planning and developing multimedia products.
 
Perpanjangan dan Pembaruan Hak Atas Tanah Bagi Investor di Ibu Kota Nusantara
Indonesia is a developing country that is trying to carry out national development. National development in Indonesia is philosophically based on Pancasila and the 1945 Constitution of the Republic of Indonesia, as Pancasila is the way of life of the Indonesian nation. The essence of national development is to realize national goals, one of which concerns social welfare. Social welfare is closely related to economic development. The Indonesian nation is currently making efforts to accelerate economic development towards stability and economic growth by paying attention to aspects of economics overeignty. Efforts to accelerate economic development are achieved through investment by making maximum use of fertilization and utilization of domestic investment and foreign investment. In 2022, the Government of the Republic of Indonesia promulgated Law Number 3 of 2022 concerning the National Capital which regulates there location of the National Capital, one of which is due to the economic gap between Java and outside Java and there are studie swhich show that Jakarta is no longer able to carry out its role as the capital city. The Government of the Republic of Indonesia needs investors to support facilities and infrastructure in the new National Capital. The Minister of Agrarian Affairs and Spatial Planning or the National Land Agency emphasized that it would provide convenience for land matters, spatial planning and business licensing to attract investors to invest in the National Capital City. One way to facilitate this matter is bygranting land rights in the form of building user rights for 160 (one hundred and sixty) years to investors. The convenience provided seems to only prioritize the interests of investors and if it is realized it will create legal uncertainty for investors
Analisis Visual Kemasan Kue Gabin Samarinda Untuk Pengembangan Desain Kemasan
Heritage typical traditional food is the region typical food that is different from those from other regions. In carrying it, the food needs a container in the form of packaging. As a souvenir, the packaging needs to have a uniqueness that can differentiate it from other packages and at the same time can show its identity. One of the difference comes from the attributes of the packaging from the visual side. Because the visual appearance is the first thing that catch the costumers attention and also influences purchasing decisions. So it needs to be analyzed what attributes are required from the visual side.
This is a qualitative reasearch. Preliminary data were obtained from a literature study on food packaging design which was analyzed for its attributes, the results were qualitativeized using the NVivo application. NVivo is used to illustrate the decision analysis results framework by coding the data according to the classification scheme.
The result of this study is the arrangement of the visual attributes of traditional food packaging, which will be applied to develop the packaging design for the Samarinda gabin biscuit, to reconstruct the packaging which is suitable to current taste without losing its original identity
The Dark Triad Personality Traits in Relation to Cyberbullying: The Role of Self-Esteem as a Mediator: [Hubungan Kepribadian Dark Triad dan Cyberbullying: Peran Self-Esteem Sebagai Mediator]
A cyberbullying study in Indonesia found that 84% of young people aged 12-17 years conducted cyberbullying. The consequences of cyberbullying emphasize the importance of studying the predictors and mechanism of cyberbullying. A number of studies have found that cyberbullying is related to Dark Triad personality traits and self-esteem. Dark Triad personality traits consist of three characteristics, namely the traits of: (1) psychopathy, Machiavellianism, and narcissism. This study aims to see the role of self-esteem as a mediator in the relationship between Dark Triad personality traits and cyberbullying in the age of 20-35 years. Participants of this studi consist of 292 individuals where 70.89% of them are women. This study utilizes three scales, namely cyberbullying scale, Rosenberg Self-Esteem Scale (RSES), and Short Dark Triad Scale (SD3). The result of this study finds that self-esteem mediates traits of psychopathy toward cyberbullying. High self-esteem in individuals with traits of psychopathy results in higher trend in conducting cyberbullying. On the other hand, self-esteem may not significantly mediate between the traits of narcissism and Machiavellianism with cyberbullying. Results of this study aims to provide an implication related to the prevention or intervention of cyberbullying.
Sebuah studi cyberbullying di Indonesia menemukan sebanyak 84% anak muda berusia 12-17 tahun melakukan cyberbullying. Konsekuensi dari cyberbullying menekankan pentingnya meneliti prediktor dan mekanisme cyberbullying. Sejumlah studi telah menemukan bahwa cyberbullying terkait dengan kepribadian Dark Triad dan self-esteem. Kepribadian Dark Triad terdiri dari tiga karakteristik, yaitu sifat psikopati, Machiavellianisme, dan narsisisme. Studi ini bertujuan untuk melihat peran self-esteem sebagai mediator dalam hubungan antara kepribadian Dark Triad dan cyberbullying pada usia 20-35 tahun. Partisipan studi terdiri dari 292 individu, dengan 70,89% merupakan perempuan. Studi ini menggunakan tiga alat ukur yaitu skala pengukuran cyberbullying, Rosenberg Self-Esteem Scale (RSES), dan Short Dark Triad Scale (SD3). Hasil studi ini menemukan bahwa self-esteem memediasi sifat psikopati terhadap cyberbullying. Self-esteem yang tinggi pada individu dengan sifat psikopati menghasilkan kecenderungan yang lebih tinggi dalam melakukan cyberbullying. Di sisi lain, self-esteem tidak memediasi secara signifikan antara sifat narsisisme maupun sifat Machiavellianisme dengan cyberbullying. Hasil studi ini diharapkan mampu menyediakan implikasi sehubungan pencegahan atau intervensi cyberbullying.
 
THE APPLICATION OF NON-TAXABLE SALES VALUE OF TAX OBJECT IN THE CALCULATION OF LAND AND BUILDING TAX
Land and Building Tax is given on land and building ownership for state revenue. While the Selling Value of Non-Taxable Tax Objects (NJOPTKP), is one of the components in calculating Land and Building Tax (L&B). Calculating Land and Building Tax determined by Sales Value of Tax Object (NJOP) and NJOP increases every year. The problem is whether or not NJOPTKP, used as a deduction for NJOP, influences the calculation of L&B Tax due to the absence of material changes from the deduction. In this study, NJOPTKP of L&B Tax was analyzed using a qualitative descriptive dan quantitative method by comparing changes in Non-Taxable Income of Income Tax (PTKP), and L&B taxes between Indonesia and other countries. The analysis results indicated that economic quantities such as inflation, Regional Minimum Wages and changes in PTKP of Income Tax were not related to changes in NJOPTKP. The application of L&B Tax does not consider the status of land and buildings (whether or not it is productive) and the family status of the subjects who own the land and buildings. As a result, NJOPTKP does not have a material meaning for the calculation of L&B Tax due to the absence of a significant adjustment when compared to the increase in the NJOP on Rural and Urban Sectoral L&B Taxes (PBB-P2) and Plantation, Forestry and Mining Sectoral L&B Taxes (PBB-P3)
Pengaruh Variasi Konsentrasi Dinatrium EDTA Terhadap Stabilitas Fisika dan pH Sediaan Salep Ekstrak Etanol Daun Jambu Biji (Psidium guajava L.)
Daun jambu biji (Psidium guajava L.) merupakan salah satu tanaman yang berkhasiat, karena mengandung metabolit sekunder saponin, tanin, flavonoid, serta alkaloid. Senyawa-senyawa tersebut memiliki sifat antibakteri. Kandungan antibakteri pada daun jambu biji ini menjadi dasarpengembangan sediaan dalam bentuk salep yang berkhasiat sebagai antibakteri dengan memvariasikan salah satu bahan sebagai penstabil yaitu dinatrium EDTA. Tujuan dari penelitian ini adalah mengetahui pengaruh konsentrasi dinatrium EDTA tehadap stabilitas fisika sediaan salep ekstraketanol daun jambu biji (Psidium guajva L.). Dalam penelitian ini dibuat 3 formula dengan variasi konsentrasi dinatrium EDTA yaitu F1 (0,05%); F2 (0,08%) serta F3 (0,10%). Evaluasi stabilitas fisik sediaan salep dilakukan selama 12 hari (6 siklus), meliputi uji organoleptik, uji homogenitas, uji pH, uji daya lekat, uji daya sebar dan uji stabilitas. Hasil pengamatan organoleptik selama cycling test menunjukan adanya perubahan warna pada sediaan yaitu pada siklus ke 5 dan 6. Selain itu, dengan bertambahnya konsentrasi dinatrium EDTA berpengaruh terhadap pH. Semakin tinggi konsentrasi dinatrium EDTA maka semakin kecil pH dan berpengaruh pada stabilitas fisika sediaan. Hasil menunjukan bahwa sediaan yang stabil dan memenuhi syarat yaitu formula 3 dengan konsentrasi dinatrium EDTA 0,10 %.
Guava leaves (Psidium guajava L.) is one of the efficacious plants, because it contains secondary metabolites of saponins, tannins, flavonoids, and alkaloids; where these compounds have antibacterial properties. With the presence of antibacterial content in guava leaves, a preparation was made in the form of an antibacterial ointment by varying one of the ingredients as a stabilizer, namely disodium EDTA. The purpose of this study was to determine the effect of disodium EDTA concentration on the physical stability of the ethanol extract ointment of guava leaves (Psidium guajva L.). In this study, 3 formulas were prepared with variations in the concentration of disodium EDTA, namely F1 (0.05%); F2 (0.08%) and F3 (0.10%), respectively. Evaluation of the physical stability of the ointment was carried out for 12 days (6 cycles), including organoleptic tests, homogeneity tests, pH tests, adhesion tests, spreadability tests and stability tests. The results of organoleptic observations during the cycling test showed that there was a change in the color of the preparation in the 5th and 6th cycles. In addition, increasing the disodium EDTA concentration affected the pH, where the higher the disodium EDTA concentration, the lower the pH and affected the physical stability of the preparation. The results showed that the preparation that met the requirements for ointment stability was formula 3 with a concentration of 0.10% disodium EDTA