Journal Of Advanced Zoology
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A Pilot Study To Test The Reliability And Validity Of The Research Instrument Designed For Enhancing Employability Skills Amongst Students
Get PDFEmployability is a set of skills, achievement, personal attributes which makes the student more employable. This research paper tries to explore the factors which can be most influencing for the purpose of enhancing employability skills amongst students. The research is based on survey where simple technique of data collection through Google form is used. As we know that before starting collection of primary data the pilot study is very important. This study focuses on testing the reliability and validity of the designed questionnaire. The questionnaire focuses on questions related to teaching pedagogies, parts of teaching pedagogies which are important other than classroom teaching and to check if the students are kept well informed about their analysis of their skills. In this study SPSS is used to test the reliability and validity of the research instrument
Synthesis, Characterization And In-Vitro Studies On Chalcone Based Quinoxaline: Acetylcholinesterase Inhibition Through In-Silico Technique For Alzheimer’s Disease
Get PDFInhibition of Acetylcholine esterase (AChE) to prevent the reduction of ACh level in Alzheimer’s disease (AD) patients has been a popular strategy. Therapeutic applications of chalcones and Quinoxalines are becoming the attractive target due to its inherent diverse biological properties in recent times. In this study, virtual library was created containing 15 novel chalcone-quinoxaline hybrid derivatives using CHEMDRAW. Toxicity and ADME properties of those compounds were screened using admetSAR. 2D-QSAR in-silico models were developed to predict the activities of newly designed compounds before a decision is being made whether these compounds should be really synthesized and tested. In addition, docking studies had performed for newly designed compounds using PyRx software. 15 compounds were synthesized and characterized by IR, 1H NMR, 13C NMR and LC-MS. Then all compounds were tested for cell viability in-vitro MTT assay. Among the tested compounds, M2 and M4 were shown to be the most effective against the evaluated cell lines. In-depth, detailed investigations on in-vivo activity may be undertaken. The current study suggests that more research is needed for chalcone merged quinoxaline derivatives developed as a potent lead for Alzheimer\u27s disease.
 
Evaluation Of Peri Implant Tissue Displacement Around Single Piece Implants Using 3 Different Displacement Methods - A Clinical Study
Get PDFPURPOSE: To compare and evaluate vertical displacement, lateral displacement and pressure during peri implant tissue displacement using 3 different displacement methods.
MATERIALS AND METHODS: Ten single piece implants were placed and provisional crowns were given. After a period of six months, primary impressions were made and casts were poured. Over these casts, custom trays were fabricated (n=40). A Pre displacement impression was followed by Mechanical (G cuff), Chemical (astringent retraction paste) and Chemico-mechanical (knitted retraction cord) displacement in a gap of seven days. Pressure measurements were made using customized pressure sensitive periodontal probe. Impressions were made and the forty die stone casts obtained were scanned and analysed to measure the vertical and lateral displacement. The statistical analysis was done using Kruskal Wallis test followed by Post Hoc analysis - Scheffe’s method.
RESULTS: The highest vertical displacement was seen in Chemico-mechanical (knitted retraction cord) followed by Mechanical (G-cuff) and Chemical (astringent retraction paste). The highest lateral displacement was seen in Mechanical (G cuff) followed by Chemico-mechanical (knitted retraction cord) and Chemical (astringent retraction paste). Least pressure was seen with chemical (astringent retraction paste) method followed by mechanical (G cuff) and chemico – mechanical (knitted retraction cord) method.
CONCLUSION: Lateral peri implant displacement is more predictable than vertical peri implant displacement. All the methods tested showed pressure within acceptable limits during displacement procedures. Chemical (Astringent retraction paste) method produced desirable displacement with least pressure to the surrounding tissues
Qbd Approach Of Analytical Method Development And Validation Of Camylofin And Mefenamic Acid In Bulk And Pharmaceutical Dosage Form
Get PDFA simple, Accurate, precise method was developed for the estimation of the Camylofin and Mefenamic acid in bulk and pharmaceutical dosage form. The chromatogram was run through HSS 100 x 2.1 mm, 1.8. Mobile phase containing 0.1N Phosphate buffer: Methanol taken in the ratio 55:45 (% v/v) was pumped through the column at a flow rate of 0.2 ml/min. Temperature was maintained at 30°C. The optimized wavelength selected was ACQUITY TUV detector ChA 220.0 nm. Retention time of Camylofin was found to be 1.455 min Mefenamic acid was found to be 1.099 min. %RSD of the Camylofin and Mefenamic acid was found to be 0.9 and 0.9. %Recovery was obtained as 99.97% for Camylofin and 100.44 for Mefenamic acid. LOD and LOQ values obtained from regression equations of Camylofin were 0.03 and 0.08 respectively, and the Regression equation is y = 37722x + 1092.5. LOD and LOQ values obtained from regression equations of Mefenamic acid were 0.08 and 0.23 respectively, and the Regression equation is y = 30948x +6750.5. The chromatographic run time was decreased and method was rugged and robust, so the method developed was simple and economical and can be adopted in regular Quality control test in Industries
In Vitro Antioxidant Activity Of Oak Gall Oil And Triphala Oil
Get PDFTraditional Indian literature have evidenced the usage of Oak gall and Triphala for common ailments to oral malignancies and other lifestyle disorders. The objective of the study is to examine the antioxidant activity of oak gall oil (OGO) & Triphala oil (TPO). Oak gall oil (OGO)) and Triphala oil (TPO) were produced with purified oil from coconut in a proportion of 1:5, with one portion of gall of Oak / Triphala added to five parts of the oil of coconut. Oak gall & Triphala oil were evaluated for antioxidant capabilities using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, the Hydroxyl radical scavenging activity and the Nitric oxide radical scavenge action. In the DPPH experiment, ascorbic acid served as the comparison standard, while gallic acid was utilized to measure nitric oxide activity in reducing radicals and the hydroxyl radical scavenge activity. The percentage inhibition of Oak gall oil (OGO) & Triphala oil (TPO) was 75.2%, and 67.4% for DPPH assay,48.4% and 63.3% for Hydroxyl radical scavenging assay, 51.2% and 52.7% for Nitric oxide radical scavenging assay respectively with ascorbic acid (89.1%) and Gallic acid standard (62.9% and 70.4%) used as comparative respectively. The study results show that Oak gall oil (OGO)and Triphala oil (TPO) possess antioxidant properties comparable to reference standards. Products derived from native plants, such as oak gall & Triphala, if proven to be effective in-vivo, can serve as a simple, safe, cost-effective and culturally acceptable adjuvant in anticancer managemen
Innovation And Technological Entrepreneruship
Get PDFEntrepreneurship is the process of creating, managing, and developing a new business venture in order to achieve success in the marketplace. Technological innovation plays a critical role in entrepreneurship, as it provides opportunities for entrepreneurs to create new products and services, and to improve their business operations. In this article, we will explore the role of technological innovation in entrepreneurship, and how it has revolutionized the way we do business. Technological innovation is the process of creating new and improved technologies that can be used to solve problems, improve efficiency, and provide new opportunities for businesses. It is an ongoing process that involves research and development, testing, and commercialization of new technologies. In the last two decades, technology entrepreneurship, involving two established but related fields, entrepreneurship, and technology-based innovation, attracted researchers and policymakers’ interest due to the recognized positive effect on economic development. Considering technology, innovation, and entrepreneurship as the main forces to achieve sustainable development at different levels of the economy and society, it is vital to assess and develop the ability to synergetic create these forces
Processing Of Milled Cotton Seeds In An Electric Magnetic Field Of Extremely High Frequency Laboratory Device And Experimental Analysis
Get PDFIn this article, the laboratory device for processing milled cotton seeds in an electric magnetic field with an extremely high frequency and the results of the experiment obtained are described. The volume of macro pores of the gourmets (from 1875 to 7500), processed at 2450 MGs, 300 W, at 12-14% humidity for 13-15 minutes, increased by an average of 2.0 – 2.2 times after ultra-high-frequency processing, and when comparing the acid and perekis number indicators of high gossipol cotton oil with oil obtained using traditional technology, compared with processing using frequency Beams has been shown to be more efficient than in the traditional method
 
Understanding Of Concept Of Viruddhahara (Incompatible Food) In The Light Of Conventional Science
Get PDFFood incompatibility (Virudhaahar) is described elaborately in Ayurveda health science. Various types of food incompatibilities with the examples of combination are mentioned in the Ayurveda literatures like in Charaka Samhita and Susruta Samhita but these type of food combinations are not practiced in today\u27s era. Today with the change in lifestyle, food processing methods and the combination of food articles are also modified. So, there is a need to review and identify new food incompatibilities, which are currently practiced as per Ayurvedic perspectives. Such food combinations can prove harmful, which may be imparting its untoward effects on the immune system, cellular metabolism, hormone secretions, and hence, the need to acknowledge this health issue arise. The unwanted effect of wrong combinations of food is not limited up to gastrointestinal tract only but may hamper the major systems of the body as well. Thereby, unwanted side effects can emerge inside the body when two or more types of foods are consumed together. This review article is an endeavour to compile and critically analyse the researches reporting the incompatible food effects with their probable pathogenesis and to identify new food incompatibilities, which are currently practiced
Strengthening Of Mechanical Properties Of Engineered Cementitious Composites By Addition Of Fibres
Get PDFCementitious Composite (CC) is a mixture of several materials that, when combined, create a composite that aids in the bonding of different structural components. The building sector has continued to employ this combination since ancient times. As CC is essential to the structural integrity of buildings, we sought to adjust the mix in this work to provide better outcomes for the composite. Whether it be masonry, concrete, or another component, the presence of CC increases a building\u27s capacity by ensuring effective bonding between two structural materials in the form of a connection. Therefore, a suitable CC is required for the building. Failure may also occur in the connection, failure in the bonding of two sections, failure in a structural component, etc., since failure in the structure often comes from the CC. The made Designed Cementitious Composite (ECC), which we found to have better flexibility and more grounded strength at a less expensive expense and diminished fossil fuel byproduct, is the subject of this paper\u27s conversation. Thusly, the designs would be better prepared to endure parallel shocks welcomed on by seismic anxieties. Since its commencement in the mid 1990s, this article has analyzed the innovative work of Designed Cementitious Composites (ECC) during the most recent decade. In the materials configuration approach, the meaning of micromechanics is worried. A variety of theoretical and experimental studies are used to examine observations of distinctive ECC characteristics
Teratogenic Effects of Di(2-Ethylhexyl) Phthalate (DEHP) on Zebrafish Embryos
Get PDFDevelopmental toxicity studies help to understand the impact of a pollutant on this crucial phase of the living organisms which can affect their population dynamics. Zebrafish has become an ideal model for studying environmental and embryo toxicity. The present study was carried out using zebrafish embryos for assessing the environmental toxicity of Di(2-ethylhexyl) phthalate (DEHP) which is universally considered to be an omnipresent environmental contaminant as it is the most widely used plasticizer. The embryos were exposed to DEHP for a range of five concentrations of 0.2, 20, 80, 140 and 200 μg/L for the duration of 96 hours. The treatment resulted in increased mortality and decreased hatch rate, hatchability and heartrate. It also induced teratogenic endpoints like yolk sac edema, pericardial edema and spinal deformity in the embryos which increased in dose and time dependent manner