Journal Of Advanced Zoology
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Comprehensive In-Silico Study Of PLAT Domain Containing Protein 1 Upregulated From Salinity Stress In Oryza Sativa
Get PDFSalinity stress is one of the most detrimental causes of productivity loss and death among plants including crops. Worldwide, rice is the most common staple food and also, most commonly under stressed crop. Plant protein with single PLAT (Polycystin-1, Lipoxygenase, Alpha-toxin and Triacylglycerol lipase) domain and PLAT plant stress protein family are found in most angiosperms. The exact mechanism of PLAT plant protein isn’t assuredly understood yet available reports suggest, overexpressed PLAT1 protein enhances abiotic stress, especially temperature and salt tolerance along with heavy metal stress tolerance in plants. In Arabidopsis and tobacco plant, PLAT1 appeared to be a positive mediator for growth under non-stressed condition, ABA signalling and ER stress tolerance. PLAT1 is also present in Oryza sativa both in indica and japonica group. Most of the proteins were predicted, hence lacking proper PDB structure. So, this study intended to find the possible structural resemblance between PLAT1 both in Oryza and Arabidopsis. Possibly to understand the nature of mechanism by building homology models by using SWISSMODEL and comparing sequences by MSA. Thus, encouraging further scientific use and proteomic study in order to improve salinity stress tolerance and crop yielding
Antidote effect of Bacopa moneri against arsenic induced toxicity in rats
Get PDFArsenic catastrophe has caused serious health hazards to the exposed population. An estimated 10 million people are exposed to arsenic poisoning through groundwater. The arsenic contamination through ground water has caused health diseases such as skin manifestations, loss of appetite, nausea, bowel disorders, neurological disorders etc. Therefore, there is need for search for proper therapeutic drug against arsenic induced toxicity in rats.
In the present study, arsenic induced toxic model was developed by treating Charles Foster rats (n=18) with sodium arsenite orally at the dose of 8 mg/kg body weight daily for 60 days followed by administration of Bacopa moneri (Brahmi) leaf extract at the dose of 30mg/kg body weight daily by gavage method for 60 days. After the completion of the experiment, all the animals were sacrificed and their blood samples were collected along with their vital tissues. Following parameters were assayed such as haematological assay, biochemical assay and histopathological evaluation in the present study. The haematological study comprised of RBC counts, WBC counts, platelets counts and heamoglobin percentage. For biochemical evaluation, the liver function test and the kidney function test parameters along with free radical assay were carried out. The histopathological study also showed very high degree of degeneration in the hepatocytes and the nephrocytes in the vital organ’s liver and kidney. But, after the administration of ethanolic leaf extract of Bacopa moneri, there was marked restoration in the studied parameters. The haematological parameters, the biochemical parameters as well as the histopathological study showed very significant outcomes. Therefore, the present studied medicinal plant Bacopa moneri possesses antidote effect against arsenic induced toxicity in Charles Foster rats which can be used as therapeutic drug in the future after clinical approval
Prey and host records of Coccinella spp. (Coleoptera: Coccinellidae) in India (A review)
Get PDFAphids (Hemiptera: Aphididae) are small soft bodied plant lice, their number rapidly rise above economic threshold level in suitable climatic condition due to parthenogenetic development. They have great agricultural importance due to polyphagism, polymorphism, parthenogenetic viviparity and remarkable ability to transmit various pathogenic viruses. They damage the crops directly by sucking the nutrients that cause devitalisation of plants. Many coccinellids are predators and major biological control agents of hemipteran pests such as aphids, mealy bugs, scale insects, white flies, as well as thrips and mites and other soft bodied insects. Due to predaceous nature, seasonal synchromy with their specific preys, high foraging performance, immense predation potential and high reproductive efficacy, they possess the potential to be effectively employed in Integrated Pest Management. Globally, more than 6000 ladybird beetle species are known to us, out of which, 261 predaceous species belonging to 57 genera reported from India. In biological control programme, several coccinellids predators are reported as effective bioagent against aphids viz., Aphidecta obliterata on Adelges piceae, Cheilomenes lunata on Aphis craccivora, Coccinella sexmaculata on Aphis aurantii and Myzus persicae, Coccinella transversalis on Aphis aurantii and Myzus persicae, Coccinella undecimpunctata on several aphids. In India, 13 species of coccinellids viz., Coccinella krikkeni Iablokoff-Khnzorian, Coccinella lama Kapur, Coccinella luteopicta (Mulsant), Coccinella magnopunctata Rybakow, Coccinella marussii Kapur, Coccinella nigrovittata Kapur, Coccinella repanda Thunberg, Coccinella saucerottei Mulsant, Coccinella septempunctata Linnaeus, Coccinella transversalis Fabricious, Coccinella transversoguttata Faldermann, Coccinella undecimpunctata Linnaeus and Coccinella undecimpunctata aegyptiaca Reiche are reported. Among these, C. septempunctata and C. transversalis are very common and widely distributed in India
A Study On Anti diabetic Properties in Different Herbal Products
Get PDFDiabetes mellitus is one of the common metabolic disorders acquiring around 2.8% of the world\u27s population and is anticipated to cross 5.4% by the year 2025. Since long back herbal medicines have been the highly esteemed source of medicine therefore, they have become a growing part of modern, high-tech medicine. In view of the above aspects the present review provides profiles of plants (65 species) with hypoglycaemic properties, available through literature source from various database with proper categorization according to the parts used, mode of reduction in blood glucose (insulinomimetic or insulin secretagogues activity) and active phytoconstituents having insulin mimetics activity. 
Physical And Chemical Effects On Mound Soils Of Nallamalla Forest Termites And Their Pedological Significance
Get PDFAbstract
A potentially fundamental role of termites in influencing the soil properties andprocesses of the terrestrial ecosystems is gapped here. This research on tlandscape of termite soil mounds and soil properties and their influence on microbial groups and communities is focused on the Nallamalla forest ecosystem. The soil samples were obtained from the termite hills and gardens, and then they were examined for texture, moisture level, pH, total organic carbon (TOC), total nitrogen (TN) and available phosphorus (P). Data demonstrate that the sand/clay ratio of mound soils increased to more than twice (45%). 2%), moisture content (15. 2%), pH (7. 0), TOC (2. 0%), TN (0. The doblows (as parabolic shaped discs of plant-like growth is referred to) are deep-rooted (up to 2m or 20 cm), exudate P (20.1 mg/kg) to a level that is over three times that of the surrounding soils. While, in the termite mound soil microbial community chains analysis indicates the higher bacterial and fungal diversity (Proteobacteria – the dominant group with a share of 35%, and Actinobacteria – the other most representative group that has 25%), the main fungal groups are Ascomycota (they have 50% share) and Basidiomycota (30%). This implies that the role of termites is that there is a major influence soil properties and microbial communities and this should be known since they play the ecosystem function and maintain resilience
The Effect Of Mdt(Mckenzie Protocol) In Postpartum Lower Back Pain In Women.
Get PDFStudy Design: Experimental Study
Objectives: To evaluate the effect of the McKenzie Protocol (MDT) on postpartum lower back pain in women.
Background: Lower back pain (LBP) is a prevalent condition among postpartum women, significantly impacting their quality of life. Traditional interventions include exercise, physical therapy, and pain management techniques. The McKenzie Protocol, known for its focus on self-management and directional preference exercises, offers a promising approach for alleviating LBP.
Aim of the Study: To assess the impact of MDT on reducing pain and improving functional outcomes in postpartum women with LBP.
Methodology: This experimental study involved 30 postpartum women aged 20-30 years, divided into two groups. Group A (control) received core activation exercises, while Group B (experimental) received MDT along with core exercises. Outcomes were measured using the Numerical Pain Rating Scale (NPRS) for pain, the Oswestry Disability Index (ODI) for functional disability, and spine range of motion (ROM) assessments. Participants were evaluated over a period of four weeks.
Results: Post-intervention, Group B exhibited a significant reduction in pain levels (NPRS: 3.5 ± 1.2) compared to Group A (5.0 ± 1.3) (P = 0.01). Functional disability scores (ODI) improved significantly in Group B (20.5 ± 5.5) compared to Group A (28.0 ± 6.0) (P = 0.002). Additionally, Group B demonstrated greater improvements in spine ROM, particularly in flexion (55 ± 8 degrees vs. 50 ± 9 degrees) (P = 0.03).
Conclusion: The McKenzie Protocol is effective in reducing pain and improving functional outcomes in postpartum women with lower back pain. Incorporating MDT into postpartum rehabilitation programs may enhance recovery and quality of life
Testicular Dysfunction Via Uvb-Induced Hyperthyroidism And Prophylactic Glycyrrhizin Dose In Swiss Albino Mice
Get PDFThis study explores the protective potential of glycyrrhizin, a compound from licorice root, against UVB-induced testicular dysfunction. UVB exposure disrupts hormonal balance, potentially leading to impaired male fertility. Glycyrrhizin\u27s established antioxidant and anti-inflammatory properties suggest its efficacy in mitigating these detrimental effects.
A rodent model will be employed, with controlled UVB irradiation mimicking hyperthyroidism-induced testicular damage. Testicular function will be assessed via sperm quality and motility. Additionally, oxidative stress markers (malondialdehyde) and antioxidant enzyme activity (SOD, CAT, GSH) will be evaluated. Histological examination will reveal potential alterations in spermatogenesis and seminiferous tubule structure.
A crucial aspect involves administering glycyrrhizin to a designated UVB-exposed group. Comparing parameters between control, UVB-exposed, and glycyrrhizin-treated groups will elucidate its potential to reduce oxidative stress and preserve testicular health.
This research aims to shed light on glycyrrhizin\u27s protective role against UVB-induced testicular toxicity. By evaluating its efficacy in mitigating oxidative damage and preserving testicular function, this study can contribute valuable insights for developing therapeutic strategies to safeguard male reproductive health following UVB exposure. The findings may hold particular relevance for individuals with high occupational UVB exposure or undergoing phototherapy treatments utilizing UVB radiation
The Efficacy Of Faradic Stimulation On Gluteal Amnesia In IT Professional
Get PDFStudy Design: Experimental Study
Objectives:
To observe the use of faradic stimulation concerning gluteal amnesia in IT profession.
To observe the efficacy of faradic stimulation concerning gluteal amnesia in IT.
Background: Gluteal amnesia, characterized by insufficient activation of the gluteal muscles, has become increasingly prevalent among IT professionals due to prolonged sedentary lifestyles. This condition not only affects posture but also contributes to compensatory injuries in the lumbar spine, knee, and ankle joints.
Aim of the study: To study the efficacy of faradic stimulation on gluteal amnesia in IT profession.
Methodology:
This experimental study employed a pre-test/post-test control group design over a four-week period. Participants were divided into two groups, Group A (experimental ) received targeted faradic stimulation and while Group B (control ) serving as a control grouped. Outcomes were measured using the Over Head Squat Test, pelvic tilt using pelvic Inclinometer and Active Knee Bent Test.
Results:
Results indicated a significant improvement in the activation of the gluteal muscles and a reduction in compensatory muscle patterns. This study underscores the potential of faradic stimulation as a viable treatment option for gluteal amnesia, especially for individuals engaged in predominantly sedentary work environments.
Conclusion:
These findings suggest a promising avenue for occupational health interventions aimed at reducing workplace-related musculoskeletal disorders among IT professionals
In vitro Alpha-Amylase and Alpha-Glucosidase Inhibitory Activity of Solanum Nigrum L Crude Extracts
Get PDFSolanum nigrum has traditionally been used to treat diabetic person as it contains various phytochemicals which are widely used to treat various ailments. In the present work Total Phenolic Content (TPC), Total Flavonoid Content (TFC), antioxidant and antidiabetic activities of 80% (v/v) methanolic crude extract of S. nigrum was done. Total amount of phenols in methanolic extract of fruit, leaves, stem and root of S. nigrum were found to be 63.31, 102.70, 47.96 and 62.17 µg/ml respectively. The flavonoid content was found 23.72, 128.11, 13.54 and 25.12 µg/ml in fruit, leaves, stem and root respectively. The IC50 values in µg/ml for DPPH scavenging activity of various parts of S. nigrum plant was found to be 38.77 for fruit, 51.45 for leaves, 56.35 for stem and 114.57 for root. The IC50 values for ABTS radical scavenging activity of different parts of S. nigrum plant were found to be fruit (46.93) leaves (51.26), stem (55.96) and root (101.35) µg/ml. The IC50 values in µg/ml for Alpha-amylase activity of different parts of S. nigrum plant was found to be fruit (49.47) leaves (62.83), stem (84.42) and root (178.75).The IC50 values in µg/ml for Alpha-glucosidase activity of different parts of S. nigrum plant was (154.36) for fruit, (163.93) for leaves, (180.10) for stem and (194.17) for root. This study provides a valuable insight into the therapeutic potential of S. nigrum plant constituents for managing diabetes and warrants further research and clinical investigation for practical applications in diabetic patients
Age Estimation by Cemetal Annulations (A Short Study)
Get PDFBackground:- Cementum (hard tissue of root), is deposited in layers around the dentin all throughout life. Root cementum is visible as alternate light and dark rings known as incremental lines of cementum under light microscopy. These annulations can be reliably used for age estimation in forensic science.
Aim & Objective:-To determine age estimation of human skeleton by cemental annulations of extracted tooth. The primary objectives of the study were to count number of cemental annulation of freshly extracted human teeth after longitudinal cross-section and to compare the results with actual age of the patients.
Materials & Method:-30teeth were selected and sectioned longitudinally. Sections were ground, mounted and viewed under a bright light microscope. The area selected for counting was photographed under 4X &10X objectives, cemental lines were counted and added to the eruption age of that patient, to obtain the chronological age.
Results:-Mean estimated age (MEA) was 45.95 years and mean actual age (MAA) was 45.42 years. The difference in the values between actual and estimated age was seen to be varying from +6 years to -3 years (approximately 9 years difference). Standard deviation was 2.77, z-value of 0.5 and p-value was 0.62 which was not significant. Correlation co-efficient showed a value of 0.98, proving strong positive correlation between the both the groups.
Conclusion:- The application of cemental annulations to determine age estimation suggestively serves as a valuable aid in forensic dentistry to identify the approximate age of an individual