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    QUALITY OF LIFE OF PATIENTS WITH CIRRHOSIS OF THE LIVER

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    More often, cirrhosis develops with prolonged alcohol intoxication (according to various data, from 40-50% to 70-80%) and against the background of viral hepatitis B, C and D (30-40%) and parasitic infections. More rare causes of cirrhosis are diseases of the biliary tract (intra— and extrahepatic), congestive heart failure, various chemical (hepatotoxins) and drug intoxication. Cirrhosis can also develop with hereditary metabolic disorders (hemochromatosis, hepatolenticular degeneration, α1-antitrypsin deficiency) and occlusive processes in the portal vein system (phleboportal cirrhosis).Among the infectious factors: chronic viral hepatitis, especially B and C and parasitic infections, especially fungal and fluke infections (schistosomiasis, opisthorchiasis, candidiasis, aspergillosis). Primary biliary cirrhosis of the liver occurs primarily for no apparent reason. In approximately 10-35% of patients, the etiology remains unclear.  The destruction of hepatocytes is an extremely dangerous process, since these cells perform many important functions: they participate in metabolic processes and secretory activity (excretion of bile and processed substances into the intestine), neutralize toxins and other harmful substances. As a result, the liver ceases to perform its functions in full: harmful substances enter the circulatory system, causing intoxication of the body

    PEDAGOGICAL CONDITIONS FOR THE IMPLEMENTATION OF INDIVIDUAL EDUCATION

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    The article emphasizes that currently ensuring the organization of the educational process based on individual learning technologies is one of the most urgent tasks. Learning technology-first, as a pedagogical technology means a range of procedural actions. It provides opinions about the guaranteed achievement of promising results within a set time, in the face of the variability of the educational process

    ACTIVATION OF INDEPENDENT STUDENT STUDY ON THE BASIS OF MODERN APPROACH

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    This article presents the theoretical and functional structure of activating students' independent learning through the design of educational and pedagogical activities on the example of general professional sciences. Also, the pedagogical process, the pedagogical system and its stages, algorithms of educational activity, didactic materials needed to activate the independent learning of students are presente

    LINGUOCULTURAL FEATURES OF PHRASEOLOGY IN UZBEK AND GERMAN LANGUAGES

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    This article briefly discusses phraseology in Uzbek and German. The views of the German linguist II Chernishyova on phraseology are theoretically illuminated

    THE VIEWS OF MEDIEVAL EASTERN THINKERSTHE ROLE OF YOUTH IN ETHICAL EDUCATION

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    The article analyzes the measures taken to radically improve the system of spiritual and educational work in the Republic of Uzbekistan. The views of medieval Eastern thinkers focused on the issues of moral education of young people. The philosophical content of Eastern education is revealed. Examples of the ideas of Eastern thinkers on education are given, and their spiritual foundations are studied

    CARDIAC ARRHYTHMIAS IN PATIENTS CIRRHOSIS OF THE LIVER

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    Cirrhosis of the liver (CP) is one of the urgent problems of medicine of the last decade. This is due to a large increase in viral liver diseases, especially caused by hepatitis B and C viruses. The CPU is characterized by hyperdynamic blood circulation, which manifests itself in the form of visceral vasodilation and increased cardiac output. These violations of the system circulations in combination with high intrahepatic resistance contribute to the development and progression of portal hypertension and often represent the main complications of cirrhosis in the form of varicose bleeding and ascites. The possibility of associated specific myocardial disorders in liver cirrhosis has been recognized relatively recently. These disorders include enlargement of the left ventricular cavity associated with its diastolic dysfunction and systolic incompetence during exercise. The combination of such violations is typical for the so-called cirrhotic cardiomyopathy . Meanwhile, the syndrome of cirrhotic cardiomyopathy has not yet been definitively classified and many mechanisms for the development of myocardial dysfunction in patients with CP are unknown. The absence of these data indicates insufficient awareness of practitioners about changes in the cardiovascular system in patients with cirrhosis of the liver. Early diagnosis and clinical intervention may possibly improve the survival of these patients. In patients with cirrhosis of the liver of viral etiology, an increase in the volume of the left atrium, a violation of rhythm and conduction, prolongation of the QT interval, a decrease in heart rate variability, global longitudinal systolic ventricular function, a violation of segmental diastolic ventricular function was found. These changes are more pronounced in patients with ascite

    FUNCTIONAL STATE OF CARDIAC CYCLE PARAMETERS IN KARATE AFTER MUSCLE OVERSTRAIN

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    The work carried out studies of the parameters of the cardiac cycle in karatekas up to different ages and different qualifications, where, under the influence of various physical loads, it makes it possible to judge morphological and functional changes that reflect the process of adaptation of the circulatory system to regular physical loads, characterized primarily by the work of the heart at rest and its high performance in various types of work. A pattern of changes in the parameters of the cardiac cycle was revealed depending on the level of fitness (juniors - up to 20 years old), active athletes (up to 35 years old). With different physical loads, different age groups, the R, S, T teeth were the most variable

    FOREIGN EXCHANGE MARKET OF UZBEKISTAN AND ITS INTEGRATION INTO THE INTERNATIONAL CURRENCY MARKET

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    The article contains statistical data and relevant conclusions regarding the effective organization of the currency system of our country and strengthening its integration into the international currency market in the development of international financial relation

    THE CRUSADES AND THEIR INFLUENCE ON EUROPE

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    Human history, unfortunately, is not always a world of discoveries and achievements, but often includes a chain of countless wars. One such war is the Crusades, which took place in the XI-XIII centuries. This article discusses the final Seventh and Eighth Crusades and their impact, consequences, and results on Europe

    COLLECTIVIZATION IN KARAKALPAKSTAN AND ITS EFFECTS FOR AULS (VILLAGES)

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    The given article discusses the period of collectivization of Karakalpakstan in the late 20s and early 30s of the XX century. The nationalization of the region's resources, land and water policy, which did not give the expected result, but despite their inefficiency, the totalitarian government was increasingly gaining turnover. The reasons for all the failures were declared to be the prosperous population of the villages, bayi (richman), the clergy, mirabs, merchants and local authorities

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