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Group II Introns: Highly Structured yet Dynamic
Get PDFRNA splicing, the removal of introns and ligation of exons, is a crucial process during mRNA maturation. Group II introns are large ribozymes that self-catalyze their splicing, as well as their transposition. They are living fossils of spliceosomal introns and eukaryotic retroelements. The yeast mitochondrial Sc.ai5γ is the first identified and best-studied self-splicing group II intron. A combination of biochemical, biophysical, and computational tools enables studying its catalytic properties, structure, and dynamics, while also serving to develop new therapeutic and biotechnological tools. We survey the history of group II intron studies paralleling the trends in RNA methodology with Sc.ai5γ in the spotlight
Emerging Semiconductive Properties in Dynamically-diverse Ion-Nanoparticle Superlattices: Polymer and Colloid Highlights
No full textExpiratory Aerosol pH is a Driver of the Persistence of Airborne Influenza A Virus
Get PDFTo mitigate the spread of a viral disease, it is crucial to understand the factors that influence airborne virus transmission. However, the micro-environment to which the virus is exposed in expiratory aerosol particles is highly complex. The relative humidity, the aerosol particle size and composition, and the air composition affect virus infectivity by modulating the salt and organic concentrations within the particle, as well as the phase state. A parameter that has been overlooked is the aerosol pH. Several viruses are sensitive to acidic pH; for example, the inactivation of influenza A virus becomes very fast at pH 5.5 and below, a threshold that is quickly reached in an expiratory aerosol particle exhaled in a typical indoor environment. Therefore, aerosol acidity plays a significant role in controlling the persistence of airborne, acid-sensitive viruses such as influenza virus, and aerosol pH control could be applied to limit the risk of airborne virus transmission
VICI AG International acquires Schmidlin Labor + Service AG
Get PDFVICI AG International, a leading global supplier of valves, gas generators, and gland technology for analytical instruments, is pleased to announce that it has completed the acquisition of Schmidlin Labor + Service AG in Neuheim, ZG. The acquisition was successfully completed after intensive negotiations and extensive due diligence
Directed Self-organization of Hard and Soft Nanomaterials by DNA Hybridization: Polymer and Colloid Highlights
No full textBiorefining Twin Transition: Digitalisation for Bio-based Chemicals/Materials - Discovery, Design and Optimisation
Get PDFThe article discusses the production of platform chemicals from various biological sources, including glycerol, lignin, cellulose, bio-oils, and sea products. It presents the results of catalytic and downstream processes involved in the conversion of these biomass-derived feedstocks. The experimental approaches are complemented by numerical descriptions, ranging from density functional theory (DFT) calculations to kinetic modelling of the experimental data. This multi-scale modelling approach helps to understand the underlying mechanisms and optimize the production of platform chemicals from renewable resources
Valorisation of Plastic Waste via Catalytic Hydrocracking: a Technological Survey
Get PDFIn this work, we looked at the most recent advances in the field of plastics hydrocracking from a technology standpoint. A patent search was supplemented by a literature review to evaluate the development of the hydrocracking technology for plastics recycling. We observed that the patent and academic literature output rapidly increased over the past decade, highlighting the recent emergence of this technology to tackle the plastic waste problem. A majority of patents arise from academia, where plastics recycling is a growing research topic. Although innovations for plastics hydrocracking have been reported, most of them disclose the use of catalysts in batch reactors, whereas very few patents describe the process. Continuous operation at pilot scale will be essential to gather process data towards industrialisation and further assess the commercial viability of theplastics hydrocracking technology
Bridging the Gap Between Academia and Chemical Industry through Entrepreneurship: An Account on the Case of Hydrogen-assisted Catalytic Plastic Waste Valorisation
Get PDFHerein, we provide an account on the multi-faceted approach to scaling up a low-carbon chemical technology that originates from academia. First, we discuss technical considerations that must be met prior to industrialisation of a process. Then, we discuss the non-technical considerations such as financing, regulatory and IP rights that are required to obtain support for the project. We use our experience in plastic waste hydrocracking to reflect on strategies that can aid to improve go-to-market time in the field