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The Role of Synthetic Organic Electrochemistry in the Technological Revolution of Pharmaceutical Industry
Full text linkElectrochemistry is significantly contributing to the technological revolution of organic synthesis, where the implementation of different techniques has garnered innovative and scalable synthetic methodologies. This article explores the impact of synthetic organic electrochemistry in the pharmaceutical and agrochemical industry. Key examples in high throughput experimentation, medicinal chemistry, discovery process chemistry, and process chemistry are presented, highlighting the relevance of electrochemistry in the advancement of organic synthesis, and driving innovation in the fine chemical industry
Die Dieckmann-Kondensation: Ein Überblick über Mechanismus und Anwendungen in der Synthese komplexer Moleküle: Chemical Education
No full textDie Dieckmann-Kondensation / Dieckmann-Cyclisierung wird als wichtiges klassisches Verfahren zur Bildung cyclischer Ketoverbindungen vorgestellt und ihr grosses Potential an einer Reihe von Synthesebeispielen erläutert
Bridging Innovation and Efficiency: The Promises and Challenges of Self-Driving Labs as Sustainable Drivers for Chemistry
Full text linkSelf-driving laboratories (SDLs) are reshaping scientific discovery by combining robotics, artificial intelligence (AI), and data science to automate the full Design-Make-Test-Analyze (DMTA) cycle. This review highlights how SDLs address the inefficiencies of traditional trial-and-error methods through intelligent, autonomous experimentation. We explore key advances in AI, automation, and data infrastructure, as well as the remaining technical challenges. Applications across organic synthesis, materials science, and biotechnology (e.g. such as catalytic reaction optimization, solid-state synthesis, and protein engineering) demonstrate their transformative potential. A recurring theme is the role of SDLs in promoting sustainability by miniaturizing reactions and maximizing sample efficiency through AI and machine learning. Finally, we discuss the requirements for broader adoption, including robust hardware, interoperable software, and high-quality datasets, positioning SDLs as essential tools for next-generation sustainable research
Between Acceptance and Scepticism: An Investigation into Secondary School Students\u27 Attitudes toward Artificial Intelligence in Chemistry Education
Full text linkArtificial Intelligence (AI) is increasingly integrated into daily life and various other sectors, including medicine, agriculture, and education. While AI offers personalized learning, automated feedback, and reduced teacher workload, its formal use in schools remains limited. Nonetheless, many students already engage with AI tools such as ChatGPT to understand concepts and access information, raising questions about their perceptions and competencies. This study investigates students’ prior experience with AI in school as well as their AI literacy. Further, it examines changes after a teaching unit using AI tools and compares AI supported learning to traditional instruction. Results indicate that hands-on exposure enhances students’ self-efficacy, cognitive engagement and ethical awareness, though confidence in creating AI-driven solutions remains lower. Students valued both AI-supported and teacher-led learning, suggesting that students benefit most from hybrid approaches. Ethical considerations were prominent, emphasizing fairness and responsible use, yet technical understanding of AI design lagged behind. Overall, structured AI education can strengthen skills, ethical reflection, and problem solving, but successful integration requires balancing technological tools with teacher guidance, supporting higher-order skills, and promoting sustained engagement
