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    332 research outputs found

    Placenta Accreta Spectrum Disorder As First Trimester Pregnancy Termination Complication; Case Series

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    Placenta Accreta Spectrum (PAS) disorder is rare (2% according to ACOG) condition of pregnancy when the placenta grows deeply into myometrium. This leads to failure of placenta to separate normally from myometrium after delivery and leads to massive hemorrhage. The PAS is classified as PA (Placenta Accreta), PI (Placenta Increta) and PP ( Placenta Percreta), on basis of depth of trophoblastic invasion. Increase in no. of cesarean sections, increasing the incidence of PAS. Cesarean scar on uterus promotes placental tissue to invade deeply in subsequent pregnancy. Antenatal scanning and color imaging can detect PAS, at a very early stage. Here we are reporting 4 cases of PAS, who came to JSS Hospital with complaint of bleeding per vaginum, diagnosis is confirmed by USG. 3 of them was managed by inj. Methotrexate and hysterectomy done for 1 of them. Those who were treated with inj. Methotrexate had very good outcome for next pregnancy

    Umbrella review as a data collection tool: towards observation, analysis, and empirical transformation of qualitative drivers describing healthcare workforce shortage factors into quantitative data to support medical education interventions in a global challenge.

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    A healthcare workforce shortage of 18 million is expected by 2030, against a global demand of 80 million, and it is difficult to analyse and monitor the real drivers driving this personnel shortage on a global level. The transformation of qualitative data into quantitative data can be a strategy in this global challenge, that can implement the medical education intervention strategies

    – Foreign body ingestion in children(\u3c12 years) at a tertiary care hospital: a retrospective cohort study studying role of socioeconomic status and parental supervision.

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    Background- Foreign body ingestion is a long-standing problem concerning pediatric population. We aim to evaluate the correlation between the median time interval between ingestion of foreign body and arrival to the hospital with socioeconomic factors, effect of parental supervision and number of children in the family. We also aim to find out the deciding factors for proper selection of method of removal of ingested foreign bodies. Methods- The data was collected from patient’s admission files, medical and endoscopic records. Chi-square test was used to calculate the corelation of time since ingestion with the socioeconomic status of family, method of removal of foreign body with location of impaction, method of removal with time passed since ingestion and socioeconomic status with effect of parental supervision Results- After analysing 104 cases of foreign body ingestion (FBI), a statistically significant association between difference of time interval of ingestion of foreign body and arrival to the hospital with socioeconomic status of the family was found, that is 100% patients belonging to upper class presented to the hospital within 0 to 24 hours of ingestion of foreign body. On the contrary, 71.5% patients belonging to lower class presented after 24 hours. In accordance to the statistically significant association between parental supervision and socioeconomic class, we established that 85.7% patients belonging to lower class had no parental supervision. Method of removal depends not on the time since ingestion rather on the level of impaction in the alimentary tract. Conclusions- It is essential to keep foreign body ingestion as an important differential when young children from lower socioeconomic class who lack parental supervision present with a sudden onset of obstructive GI symptoms. Educational strategies regarding safe behaviour to alleviate myths and false beliefs have a pioneer role in FBI prevention

    Internet Gaming Disorders Amongst Medical Undergraduates in Tamil Nadu, India - A Cross Sectional Study

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    Abstract Background: Internet Gaming Disorder (IGD) or internet-related gaming addictions are characterized by severely impaired control over gaming affecting routine activities, followed by several psychological, physical and social issues. Budding medical undergraduates who are future health professionals might have positive effects on their studies and career goals when saved from internet gaming addictions. Hence, this study aimed to identify the proportion of medical undergraduate students and interns with internet gaming disorders studying in a private medical college and tertiary care hospital. Setting: A tertiary care Hospital and Medical College, Tamil Nadu, India Study design: Cross – sectional study. Participants: Medical undergraduate students and interns. Sample size: 523 study participants consisting of all medical undergraduates enrolled during the study period. Study variables: Demographic characteristics and data regarding IGD. Statistical analysis: Analyzed by frequencies, percentages, chi – square test and one – way ANOVA test. Results: 2.29% (12 out of 523) of medical undergraduates and interns were screened positive for IGD (who had a score of 71 and higher as per the IGD – 20 test). Out of six descriptive factors of behavioural addiction, the conflict factor, which denotes the aggressive and non-assertive behaviour among gamers, is found to be at a higher level with a mean of 17.333. Conclusion: This study has identified the prevalence of IGD among the study participants to some extent. Over and above, further investigations are required to discover the risk factors for and other complications of IGD among medical undergraduates

    The Life and Discoveries of Yellapragada Subbarow

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    Dr. Yellapragada Subbarow was a researcher, teacher, and a wizard of wonder drugs who constantly made efforts in the discoveries/ inventions such as vitamins, anti-vitamins, antibiotics, and many more by disentangling the mysteries of nature for the betterment of the people. He inspired the youngsters to take up the challenges and to stand up above mediocrity. The reward for his achievement was delayed. The article describes a true humanist\u27s journey, discoveries, and his achievements that are largely unknown to date

    Primary Hypertrophic Osteoarthropathy: A case series

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    Skeletal dysplasia encompasses a spectrum of over 400 rare inheritable skeletal abnormalities typically manifested early in childhood. Hypertrophic Osteoarthropathy is a clinical syndrome marked by abnormal skin and osseous tissue proliferation at the distal extremities. It is characterized by unique clinical features such as digital clubbing, periostosis of tubular bones, and synovial effusions. We report three cases of HPOA for further understanding and insight into this infrequent cause of clubbing. Case 1 involved a 25-year-old male presenting with joint pain, primarily in wrists and knees, accompanied by progressive swelling in both lower limbs for the past 3 years. Case 2 featured a 31-year-old man born out of a second-degree consanguineous marriage, reporting pain in wrist, knee, and ankle joints bilaterally for 2 years, with a history of clubbing since birth. Case 3 featured a 19-year-old male with multiple joint pains and a family history. Genetic sequencing was performed for two cases, revealing mutations in the SLCO2A1 gene associated with impaired prostaglandin E2 (PGE2) degradation, leading to elevated PGE2 levels. While primary Hypertrophic Osteoarthropathy is an uncommon cause of clubbing, the diagnosis is often challenging. Genetic sequencing played a pivotal role in confirming the diagnosis in these cases, highlighting its importance in understanding and managing this condition. These case reports contribute to the limited literature on HPOA, particularly in the context of genetic testing, which is not routinely conducted in India

    Alopecia as an Early Clinical Marker for Azathioprine Induced Myelosuppression: A Case Report

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    Azathioprine is a pro-drug and is metabolized by the TPMT enzyme in the body. In South Asians, Azathioprine is known to cause alopecia and bone marrow suppression in patients with TPMT enzyme deficiency. In India, the prevalence of TPMT mutation varies from 1.2- 10%. A new mutation was detected in 2014, NUDT15 whose incidence varies from 8.5-16%. Patients with mutation in both TPMT and NUDT15 develop myelosuppression faster. In our case, alopecia manifested as the first clinical feature of Azathioprine myelosuppression. Physicians need to recognize early clinical clues (alopecia) to avoid the impending development of myelosuppression and to look for possible gene mutations

    An Internal Audit on Patient Safety and Quality of services in a Rural Health Training Center, Coimbatore.

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    Prioritizing patient safety is imperative for enhancing quality healthcare, especially in lower- and middle-income countries. Recognizing this urgency, India\u27s Ministry of Health and Family Welfare introduced the \u27SaQushal\u27 toolkit, empowering health facilities to self-assess and improve their safety practices. This study presents an internal audit at a Rural Health Training Centre (RHTC) in Coimbatore, India, utilizing the \u27SaQushal\u27 framework. The facility achieved an overall score of 63%, exceeding the 50% minimum threshold for each domain, indicating commendable efforts towards establishing good quality standards. Notably, all domains scored above 50%, highlighting strengths across various safety dimensions. While acknowledging this progress, the audit offers valuable insights for further improvement, guiding the RHTC\u27s journey towards even more robust patient safety measures. By disseminating these findings and promoting proactive implementation of targeted interventions, we can collectively move towards safer and better healthcare for all

    Cone bean computed tomographic evaluation, localization and surgical management of Non-syndromic Inverted mesiodens in close proximity to nasal floor: Case report and review of literature

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    Supernumerary teeth are numerical developmental anomaly defined as an additional teeth present as a complement to the normal dentition. Mesiodens is relatively a most common anomaly in the developing dentition stages. This article presents the case report of a 6-year old girl child who with the chief complaint of malaligned upper front teeth. On detailed clinical and radiographic examination the presence of vertically impacted mesiodens in the anterior region with close proximity to nasal floor was noted. The child didn’t have any relevant medical or dental history. Due to pertaining complexity and its close proximation to the nasal floor it was decided to carryout extraction of mesiodens under general anesthesia. Following the extraction of mesiodens under general anesthesia after the scheduled recovery appropriate post-operative instructions were given to the child and their parents and the child was discharged. Follow up was scheduled after 1 week which showed uneventful healing of the surgical site and subsequent eruption of maxillary right lateral incisor. Mesiodens belong to the category of supernumerary teeth which can result numerous dentofacial defects if not removed promptly. Hence parents must have considerable attention and seek dental help whenever they notice an asymmetric pattern of teeth eruption in their children. In this case scenario the mesiodens were removed as it prevented the eruption of successor permanent teeth which henceforth resulted with considerable esthetic concerns for the child due to its prolonged retention within the dental arch

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