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Owyhee County Resource Guide - Idaho
Full text linkCounty level and region-specific resource guides focused on mental health and substance use
Teton County Resource Guide - Idaho
Full text linkCounty level and region-specific resource guides focused on mental health and substance use
Adams County Resource Guide - Washington
Full text linkCounty level and region-specific resource guides focused on mental health and substance use
Oneida County Resource Guide - Idaho
Full text linkCounty level and region-specific resource guides focused on mental health and substance use
GENERATIONAL STABILITY OF ENVIRONMENTALLY INDUCED EPIGENETIC TRANSGENERATIONAL INHERITANCE OF ADULT-ONSET DISEASE OVER TEN AND TWENTY GENERATIONS
Full text linkMany toxicants are released into our ecosystems and environment every day, causing harmful effects on wildlife and the human population. Vinclozolin is an agricultural fungicide used in vegetable and fruit production and has been shown to cause irreversible effects in infertility cases. Although this fungicide helps prevent molds, blights, and rots, the compound has an anti-androgenic effect, blocking the androgen receptors of the male. Vinclozolin was stopped in the European Union in 2006, but it is still being used and distributed in the United States. Recent work has shown that this fungicide affects the transgenerational (F3) generations more than the directly exposed generations (F0, F1, F2). While the directly exposed F0 generations do not have any onset effects, the later generations that are transgenerational suffer as they have no say in whether they want to be ancestrally exposed to such harmful toxicants. The stability of the epigenetic transgenerational inheritance from ancestral exposures will be investigated. In the proposed research, since transgenerational generations are given no choice and are thus left to deal with the effects passed onto them, the ethics of such effects is also considered. This thesis tests the hypothesis that “environmental toxicants released into the environment can ancestrally affect the organism's germline cells to cause the epigenetic transgenerational inheritance of germline epimutations which allows the stable generational transmission of transgenerational epimutations in all subsequent generations.” A gestating female (F0 generation) was exposed to the toxicant vinclozolin. This toxicant exposure promotes transgenerational epigenetic traits and phenotypes of infertility, obesity, and other organ pathologies and diseases. The germline cells develop these epimutations in the epigenome, to promote the increase in infertility, obesity, and other organ disease phenotypes. We will use a transgenerational inheritance model of ancestral exposure to investigate the transgenerational stability of epigenetic inheritance. This will be investigated through ancestral exposure of the F0 generation to the toxicant vinclozolin and analysis in transgenerational models of 10 and 20 generations in mammals for generational stability
Long-term nighttime aircraft noise exposure and risk of hypertension in a prospective cohort of female nurses
Full text linkThere is growing interest in cardiometabolic outcomes associated with nighttime noise, given that noise can disturb sleep and sleep disturbance can increase cardiometabolic risk such as hypertension. However, there is little empirical research evaluating the association between nighttime aircraft noise and hypertension risk. In this study, we expand on previous work to evaluate associations between nighttime aircraft noise exposure and self-reported hypertension incidence in the Nurses' Health Studies (NHS/NHSII), two US-wide cohorts of female nurses. Annual nighttime average aircraft sound levels (L) surrounding 90 airports for 1995-2015 (in 5-year intervals) were modeled using the Aviation Environmental Design Tool and assigned to participants' geocoded addresses over time. Hypertension risk was estimated for each cohort using time-varying Cox proportional-hazards models for Ldichotomized at 45 dB (dB), adjusting for individual-level hypertension risk factors, area-level socioeconomic status, region, and air pollution. Random effects meta-analysis was used to combine cohort results. Among 63,229 NHS and 98,880 NHSII participants free of hypertension at study baseline (1994/1995), we observed 33,190 and 28,255 new hypertension cases by 2014/2013, respectively. Although ∼1% of participants were exposed to L≥45 dB, we observed an adjusted hazard ratio (HR) of 1.10 (95% CI: 0.96, 1.27) in NHS and adjusted HR of 1.12 (95% CI: 0.98, 1.28) in NHSII, comparing exposure to L≥45 versus <45 dB(A). In meta-analysis, we observed an adjusted HR of 1.11 (95% CI: 1.01, 1.23). These results were attenuated with adjustment for additional variables such as body mass index. Our findings support a modest positive association between nighttime aircraft noise and hypertension risk across NHS/NHSII, which may reinforce the concept that sleep disturbance contributes to noise-related disease burden
HR Source Newsletter, June 2025
No full textIn this issue of HR Source (a newsletter for Washington State University employees): June: A Powerful Month of Reflection and Celebration; Update: 2025 WSU Employee Engagement Survey; Effective July 1, 2025: Washington State Expands Bereavement Leave Benefit
2025 pest management guide for grapes in Washington
Full text linkThe Pest Management Guide for Grapes in Washington presents various chemicals and their uses against pest problems in Washington vineyards. While the recommendations are based on eastern Washington conditions, the information may often be applied to similar pest problems found throughout the state. Specific and more detailed information on pests and diseases can be found in the Field Guide for Integrated Pest Management in Pacific Northwest Vineyards (PNW644). Recommendations are suggested guidelines. They are not intended to represent pest control programs. The use of other materials and varying rates and treatments for control of particular pests depends on individual circumstances