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O papel da educação em saúde no enfrentamento da hesitação vacinal na infância e adolescência
No full textNo cenário atual, a hesitação vacinal caracteriza-se pela recusa ou atraso na aceitação de vacinas recomendadas, frequentemente associadas à disseminação de informações falsas, tornando-se um fenômeno complexo qual afeta negativamente, e de forma crescente, as coberturas vacinais ofertadas pelo sistema público de saúde. Esse cenário afeta, principalmente, crianças e adolescentes, comprometendo a efetividade das políticas públicas de imunização. Diante disso, destaca-se a educação em saúde como uma ferramenta estratégica para o enfrentamento da mesma. Sendo assim, torna-se pertinente sistematizar as evidências científicas que abordam o papel da educação em saúde nesse enfrentamento
Altitudinal Patterns of Insect Pest and Natural Enemy Diversity in Tidore Chili Pepper (Capsicum frutescens L.): A Qualitative Systematic Review Protocol
No full textBackground and rationale:
Altitude is a key environmental gradient influencing insect pest diversity and natural enemy communities in agricultural ecosystems. Tidore chili pepper (Capsicum frutescens L.), widely cultivated across different elevation zones on Tidore Island, provides an important model for understanding elevation-related ecological dynamics. However, existing studies are fragmented across regions and systems. A systematic synthesis is necessary to identify general patterns and ecological mechanisms affecting pest and natural enemy diversity along altitudinal gradients, particularly in tropical island agroecosystems.
Objectives:
This systematic review aims to synthesize published ecological evidence on how altitude influences insect pest diversity, natural enemy communities, and pest–natural enemy interactions in chili pepper agroecosystems.
Primary research question:
How does altitude affect insect pest diversity in chili pepper agroecosystems?
Secondary questions:
1. How do natural enemies (predators and parasitoids) respond to altitudinal gradients?
2. How do pest–natural enemy interactions vary across elevation zones?
3. What ecological mechanisms explain elevation-related diversity patterns?
Eligibility criteria:
Inclusion criteria:
• Studies reporting ecological field data on insect pests and/or natural enemies
• Studies conducted in chili pepper (Capsicum frutescens L. or Capsicum spp.) or comparable crops
• Studies examining elevation or altitude gradients
• Studies reporting diversity metrics (abundance, richness, diversity indices)
• Studies conducted in tropical or subtropical agroecosystems
• Peer-reviewed journal articles
Exclusion criteria:
• Studies without primary ecological data
• Studies lacking clear sampling or identification methods
• Molecular-only studies without ecological interpretation
• Non-insect organisms
• Duplicate publications
• Unavailable full text
Search strategy:
Literature searches will be conducted using the following databases:
• Scopus
• Web of Science
• ScienceDirect
• DOAJ
• Google Scholar
• SINTA-indexed journals
• Institutional repositories
Search keywords will include combinations of:
“Capsicum frutescens”, “Tidore chili pepper”, “Capsicum spp.”,
“insect pest”, “insect diversity”,
“natural enemies”, “predators”, “parasitoids”,
“altitude”, “elevation gradient”,
“agroecosystem”, “tropical agriculture”.
Boolean operators (AND, OR) will be used.
Study selection process:
Study selection will follow PRISMA 2020 guidelines:
1. Identification
2. Screening (title and abstract)
3. Eligibility (full-text review)
4. Inclusion
Data extraction:
Data extracted will include:
• Author and year
• Study location
• Elevation range
• Crop type
• Insect taxa
• Diversity indices
• Environmental variables
• Pest–natural enemy interactions
Quality assessment:
Study quality will be evaluated using modified Critical Appraisal Skills Programme (CASP) and Joanna Briggs Institute (JBI) criteria adapted for ecological research.
Data synthesis:
A qualitative narrative synthesis will be conducted. Studies will be grouped into elevation categories:
• Low elevation: 0–200 m asl
• Mid elevation: 200–400 m asl
• High elevation: 400–700 m asl
Meta-analysis will not be performed due to heterogeneity in study design and ecological metrics.
Timeline:
Protocol registration: 2026
Literature search: 2026
Screening and extraction: 2026
Manuscript preparation: 2026
Keywords:
Capsicum frutescens, Tidore chili pepper, insect pest, natural enemies, altitude, elevation gradient, agroecosystem, systematic revie
Early-Warning Predictive Models for Student Pilot Progression
No full textThe paper evaluates how modern psychometric methods—Item Response Theory (IRT) and Computerized Adaptive Testing (CAT)—can be applied to FAA knowledge testing through calibrated adaptive item banks. From an aviation training + IT systems perspective, it argues that fixed-form testing encourages rote memorization and is psychometrically outdated, and it outlines implementation requirements (data volume, secure delivery infrastructure, exposure control) and human-factors considerations (e.g., review behavior and multistage testing)
Cumulative Cognitive Architecture: Empirical Validation of Human-Analogous Memory Principles Across Large Language Models
No full textThis study introduces and empirically validates the Cumulative Cognitive Architecture Hypothesis (CCAH): AI memory performance improves through two orthogonal dimensions — architectural sophistication (No Memory → Basic RAG → Cognitive Memory implementing 10 cognitive science principles) and structured cognitive scaffolding (Trinity framework: explicit identification of Rules, Constraints, and Fear/failure-mode elements) — where each dimension contributes independently measurable gains with potential interaction effects when combined.
A prior study (Study 1; N=2,470 trials, 6 LLM platforms) validated the Trinity intervention with d=0.64 (p<0.0001) and identified Fear identification (anticipatory failure awareness) as the dominant mechanism (η²=0.1987), dwarfing Rules (η²=0.002) and Constraints (η²=0.001) by approximately 100×. This study extends that finding to multi-session memory contexts.
We test the CCAH through a 3×2 factorial design (Memory Level × Cognitive Scaffolding) across 3 architecturally diverse LLM providers (proprietary frontier: GPT-5.2; multimodal-native: Gemini 3 Pro Preview; open-source: Llama 4 Scout via Groq). The design includes: 810 primary factorial trials, 900 LongMemEval benchmark trials for direct comparison against published baselines, a 12-condition ablation study (720 trials) isolating contributions of 10 cognitive principles, and a reserved transfer test using held-out Temporal Reasoning tasks.
Total: 2,430 trials. This provides the first systematic cross-provider factorial evaluation of cognitive science principles for AI memory systems, directly responding to the prompting replicability crisis (Vaugrante, Niepert & Hagendorff, TMLR 2025) with pre-registered hypotheses, Bayesian analysis, cross-LLM scoring validation, and bootstrap confidence intervals
Quantum Gravity Dynamics: Dark Matter and Dark energy from Quantum Gravity in Dirac Spinor Fields deriving General Relativity
No full textWe present Quantum Gravity Dynamics (QGD), deriving classical gravity from quantum wavefunction structure in flat Minkowski spacetime.
Core formalism: Bridge equation |ψ|²=C/|p| connects quantum amplitude to classical momentum. All stress-energy (mass ρ, pressure P, angular momentum J, EM field F, Λ) enters unified denominator Δ = E + mc² + ∫ρc²dV - ∫PdV - J²/(2mr²) + V_EM + ρ_Λ.
Complete wavefunction: ψ = (GMm/ℏc)[ψ₀,ψ₁,ψ₂,ψ₃] with graviton scalars σ_μ = p_μc/Δ.
Master equation: g_μν = T^α_μ T^β_ν [M_αβ ∘ (η_αβ - Σ_a ε_a σ^(a)_α σ^(a)_β - κℓ_Q² ∂σ²)]
Universal forms:
- Schwarzschild: σ_r = √(2GM/c²r)
- Kerr: σ_φ = a·sin(θ)√(2Mr/Σ)
- RN: -GQ²/c⁴r² term
- SdS: +Λr²/3 term
- FLRW: H²r² cosmology
- Wormholes: +b(r)/r
Dark matter prediction: Factorial κ-factors κ_j=√[(2j-1)!/2^(2j-2)] = [1.00, 1.225, 2.74, 8.87, 37.7, 197,...] explain rotation curves. R²=0.908 across 4,248 measurements, zero free parameters per galaxy.
Energy localization: ρ_grav(x) = ½(∂σ)² manifestly positive, resolves GR pseudotensor problem.
Key results: (1) Newton's F=GMm/r² from phase e^(2ipr/ℏ), determines k=GMm/ℏc. and higher order terms (2) All EFE solutions from master equation. (3) Quantum corrections prevent singularities. (4) Dark matter = gravitational self-energy Q_μ. (5) Positive energy trivial. (6) Two body problem analytical solution (6) three body problem calculable in QGD (7) higher order quantum effects of Hawking temperature (8) dark energy naturally emerges from Quantum gravity
Testable: rotation κ-scaling, CMB peaks (κ₄=8.87), wide binary 2% deviation, GW self-interaction.
Keywords: quantum gravity, emergent spacetime, dark matter, rotation curves, MOND, Dirac spinor, gravitational energy, master equation, factorial enhancemen
Risk Prediction Model for Postoperative Infections in Patients with Gastrointestinal Diseases: A Scoping Review
No full textDR1 - IKT zu GR – Strukturelle Herleitung der Raumzeitgeometrie
No full textThis document presents a structural derivation of core elements of General Relativity from the Invariant Core Theory (IKT).
It documents a stable internal research state and is published here as an immutable archival reference (version freeze).
The derivation proceeds through structural enforcement of geometric representation under finite closure capacity, leading to a reconstruction of metric structure and Einstein-type dynamics as regime-dependent consequences.
The document itself is written in German.
This reflects the original development context and does not affect the formal validity of the structural arguments.
Developed by Ulrich Grob in structured collaboration with the AI system “Nathan” (ChatGPT)
Inpatient Medical Care in Existential Situations: Experiences of Patients, Informal Caregivers, and Healthcare Professionals (ErExMed)
No full textThe project includes the following substudies:
The entire ErExMed study was reviewed and assessed as legally and ethically unobjectionable by the Ethics Committee of the Medical Faculty of Ruhr University Bochum, located in Ostwestfalen (2025-1443)
The Jump Maximum Function and the Subordination of Formalism
No full textThe Jump Maximum Function and the Subordination of Formalism
— A Record of Unprovability in the Collatz Mapping —
This project presents a structural record concerning the so-called Collatz conjecture.
It focuses on the behavior of the jump maximum function M(N), defined on a class of odd numbers
N = (1/2)·(a·3ⁿ − 1), where a is odd and n is a natural number.
The project consists of:
- A Japanese-language manuscript that explores the structural limitations of formal systems (ZFC)
in capturing the unpredictable behavior of M(N), and proposes a philosophical framework
in which formalism is subordinated to the integrity of record.
- An English-language version of the manuscript, preserving the structure and tone of the original,
for international accessibility and citation.
- An Excel record table that documents the behavior of M(N) across various values of a and n,
including mod 8 and mod 16 classifications, jump positions, and unpredictability markers.
This record does not claim to complete a proof.
Rather, it seals structural traces that formalism has not yet reached.
If a formal proof is ever constructed, it must be subordinated to this record as its source.
May this project serve as a lantern, quietly illuminating the limits of formalism
Replication of Frey (2024) "Larger Legislatures and the Cost of Political Brokerage: Evidence from Brazil"
No full textFrey (2024) studies the effect of council size on the electoral performance of local incumbent parties in mayoral, gubernatorial, and presidential races in Brazil. Using a fuzzy regression discontinuity (FRD) design, the author exploits exogenous variation in the number of council seats induced by population thresholds. In this replication report, we assess the computational reproducibility and robustness of the article's main finding that an increase in council size reduces electoral support for incumbent parties in the executive. We successfully reproduce the paper's results using the provided replication materials. We then check for robustness in three ways: first, we test for manipulation of the running variable. Results from a local polynomial density test indicate that municipalities did not systematically sort around the population thresholds, thereby supporting the validity of the identification strategy. Second, bandwidth sensitivity analyses show that statistical significance weakens as wider bandwidths are considered, particularly when estimates are based on individual election outcomes. Third, when using bias-corrected point estimates and robust confidence intervals, FDR estimates from most model specifications no longer reach conventional levels of statistical significance, whereas estimates based on aggregated information across elections remain largely robust. Overall, while the substantive conclusions of Frey (2024) are partly supported, the precision of the estimated effects is sensitive to modelling and inference choices