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Swarm-Coordinated AI Research Agents for Cross-Domain Hypothesis Generation in Rare Disease
No full textBio-inspired swarm coordination applied to AI research agents investigating Hereditary Alpha Tryptasemia (HaT) in a pediatric patient. Pilot feasibility study comparing swarm-coordinated vs. sequential research for cross-domain hypothesis generation. Within-subjects crossover design, N=10 topics, 20 runs
To expand or to refine basic psychological needs theory? Incremental competence versus novelty in a strong comparative test
No full textThis research project investigates whether Novelty (N), proposed as a candidate fourth basic psychological need in Self-Determination Theory (SDT), is empirically and functionally distinct from Incremental Competence (CI)—the dynamic experience of growing in ability.
To do so, the project also develops new alternative measures for Epistemic Frustration (EF) and Experiential Novelty Satisfaction (ENS), tests a 10-factor measurement model using multilevel SEM, and conducts competitive predictive tests to determine if Novelty retains unique explanatory power when Incremental Competence is controlled. Using a within-subjects design (work vs. non-work skill domains) and a 4-wave longitudinal design, the project examines both cross-sectional structure and longitudinal dynamics
Lebanese Arabic form I and their corresponding form II verbs
No full textThis database contains over 1111 triconsonantal form I verbs and over 130 biconsonantal form I verbs.
For triconsonantal form I verbs, over 680 form II verbs are listed. For biconsonantal form I verbs, over 80 form II verbs are listed
Turning the EQIPD Framework into Practice
No full textPresentation of ECNP workshop in Nice - 14.03.202
Microbiome Dysbiosis, Chemoprophylaxis, and Tumor Microenvironment in Biliary–Pancreatic Tract Diseases: a scoping Review."
No full textBiliary tract cancers (BTCs) are aggressive malignancies with poor prognosis, and patients often harbor bile-pancreatic bacteria such as Escherichia coli and Pseudomonas spp., making effective antibiotic therapy crucial to prevent resistance and complications. Disruption of the microbiota may impair tumour response to immunotherapy and chemotherapy, especially in Advanced biliary tract cancers (BTCs)
The “Normative Structure” of Social Science: Merton’s Ideas as a Story of Success and Side Effects
No full textBased on available literature, this essay looks at trends in scholarly attitudes and academic practices, primarily within the sphere of social sciences, and asks whether they have been in line with Robert K. Merton’s institutional principles of science as they were formulated in his famous essay “The Normative Structure of Science.” This essay argues that these principles have not been fully implemented but have become increasingly recognised and widely accepted as normative points of reference also in large parts of the social sciences. However, there have been both marked deviations and significant side effects. Given the internal heterogeneity of a discipline like sociology, practices that selectively interpret the Merton principles may add to existing internal cleavages
Quantifying Theoretical Progress
No full textPsychology lacks formal tools for determining whether its theories are genuinely progressing or merely accumulating supportive findings. We address this gap by applying Witte's (2025) likelihood-based hypothesis quality (HQ) and theory quality (TQ) framework to the research program lineage from the Theory of Reasoned Action through the Reasoned Action Approach, drawing on 519 effect sizes from 60 meta-analyses (1988–2025). We extend the frequentist metrics to allow negative HQ values for disconfirmation detection and supplement them with informed Bayes factors derived from founding meta-analytic estimates. Both frameworks characterized the program as consistently progressive, with cumulative TQ increasing across nearly four decades. However, per-period analysis revealed diminishing informational returns over time, and relation-level results identified systematic overprediction in two core paths where founding estimates used corrected correlations. Sensitivity analyses confirmed this reflects a metric mismatch rather than genuine theoretical disconfirmation. The frequentist and Bayesian frameworks showed strong convergence (r = .996), and conclusions were robust across four sensitivity analyses testing alternative founding specifications, subgroup treatments, and single-test relation exclusion. We introduce the distinction between progressive and maturing research programs and propose that per-period TQ analysis, negative HQ values, and dual-framework convergence assessment offer useful tools for quantitative theory evaluation in psychology
Análise da produção e implementação de vídeos educativos no ensino de estudantes de enfermagem: Integrative Review
No full textPaper III - Balanced Interaction Spectra and Berry Distributions
No full textWe study distributions on the Boolean cube {0,1}^m whose Walsh-Fourier energy is distributed equally across all interaction orders: B₁ = B₂ = ⋯ = Bₘ, where B_r = Σ_{|S|=r} p̂(S)². We call these Berry distributions — the balanced spectral counterpart to the concentrated extremizers of Papers II and IV. Computational search confirms: Berry distributions exist at m = 3, 4, 7 and are absent at m = 5, 6. The existence pattern {3, 4, 7, ...} aligns precisely with the projective-affine sequence {2^k−1, 2^k}. At m = 7 the construction is explicit: the unique Berry distribution is supported on the dual of the [7,4,3] Hamming code. We conjecture that Berry distributions exist if and only if m belongs to the projective-affine sequence, and that their supports are always cosets of self-dual or near-self-dual Reed-Muller codes. Three open problems are stated. This paper is computational and conjectural; rigorous proofs of the existence characterization are the primary open problem
Informed Integrative Care for DNM1-Related Neurologic Disorder with Compound Genetic Complexity
No full textA caregiver-developed clinical protocol and research foundation for DNM1-related neurologic disorder with compound genetic complexity, including Xp22.31 STS duplication and 8q22.2 SPAG1 duplication. Authored by Laura A. Wylesky, Prior NORD Missouri State Ambassador, OMERACT 2020 participant, OMERACT 2020 participant, published Seminars in Arthritis and Rheumatism 2021 , and Global Genes RARE Compassion Program graduate. Documents the genetic mechanism, rarity, medication warnings, intervention protocol, and informed integrative care framework for providers, caregivers, and emergency responders