38978 research outputs found
Sort by
Requirements Engineering and Simulation for System of Systems Integration: A Systematic Literature Review
No full textContext: The integration of systems in Systems of Systems (SoS) environments represents a growing challenge, especially due to the complexity of managing interoperability requirements in distributed and emergent contexts. Objectives: This systematic review identifies, analyzes, and synthesizes existing approaches for requirements management in SoS integration processes with a focus on simulation. Methods: The Scopus, Web of Science, and IEEE Xplore databases were consulted. The search, conducted between 2015 and 2025, returned 144 records. After removing duplicates and applying eligibility criteria, 20 studies were included. Methodological quality was assessed using a customized checklist
A protocol for a systematic review of the cost-effectiveness of polygenic risk scores: a scenario-based and implementation-oriented synthesis
No full textThis research project aims to systematically assess the cost-effectiveness of polygenic risk scores (PRS) in disease prevention strategies. Although PRS have demonstrated potential to improve risk stratification and enable more personalized preventive interventions, existing economic evidence remains heterogeneous and difficult to compare. The primary objective of this study is to evaluate whether PRS-based approaches are cost-effective compared with standard care or alternative screening strategies, while also examining how different modelling assumptions and implementation scenarios influence economic outcomes.
The project is based on a systematic review of peer-reviewed economic evaluations conducted in the general population. A scenario-based analytical framework will be applied to capture the full range of modelled prevention strategies reported in each study, rather than relying on a single summary estimate. Expected outcomes include a structured synthesis of cost-effectiveness results across disease areas, identification of key factors associated with favorable economic performance, and the generation of evidence to support policymakers and healthcare stakeholders in decisions regarding the integration of PRS into population-level prevention programs
Tetrometry, the Planck Quadrex, & the Unity of Physical Law
No full textThis paper introduces "Tetrometry," a geometric framework that represents the four fundamental physical quantities (Space, Time, Mass, and Energy) as vertices of a tetrahedron (termed the "Quadrex"). Building on Einstein's two great unifications (space-time via c and mass-energy via c²), the framework treats these equivalence axes as skew lines in three dimensions, naturally generating a tetrahedral structure.
The six edges of the Quadrex correspond to fundamental physical ratios (velocity, specific energy, force, power, linear mass density, and mass flow rate), while the four triangular faces map onto distinct physical domains (Dynamics, Statics, Kinematics, and Thermodynamics). The three pairs of opposite edges are shown to correspond to the three fundamental constants of physics: c (relativity), G (gravity), and ℏ (quantum mechanics).
The paper derives the Planck scale as the "unit cell" of the Quadrex where all three frameworks converge, and provides a geometric resolution of the hierarchy problem by demonstrating that the gravitational coupling constant α_G = (m/m_P)² follows directly from dimensional analysis. The dominant factor of 10³⁸ separating gravity from electromagnetism is shown to arise from the ratio of particle masses to the Planck mass, with dimensional transmutation explaining why stable particles exist far below the Planck ceiling. Finally, the framework is shown to naturally encode Lorentz invariance through the preservation of dimensionless products under coordinate transformations
Common Sense Education Community Review Archive
No full textSystematic archive of Common Sense Education community reviews for popular EdTech products. These peer reviews from teachers, parents, and students represent over a decade of firsthand accounts but are no longer easily accessible on Common Sense product pages.
This archive preserves this valuable knowledge base for parents, educators, and researchers.
Maintained by NET Lab, Inc
Barriers and Facilitators in the implementation of a psychosomatic teleconsultation service from the perspective of healthcare professionals and patients - a qualitative interview study
No full textThis interview study aims to identify and analyze facilitating and inhibiting factors for the implementation of a teleconsultation service. Previous studies have shown that psychosomatic and psychiatric consultation services can make an important contribution to closing the gaps in health care across the country, while also strengthening interdisciplinary collaboration (Kohlmann et al., 2021; Toynbee et al., 2021). In order to successfully implement such a service for patients in Saxony-Anhalt, qualitative interviews of inpatients as well as healthcare professionals will be conducted.
The results are intended to create a basis for the sustainable implementation of the teleconsultation service
Data Repository: npj Robotics
No full textThis repository contains the data files for all the experiments performed in the 3D printed Electronics-free Peristaltic Soft Robot projec
Statistical Analysis Plan
No full textMulti-Analyst meta-analysis of individual patient data on Esketamine and Suicidality - Datathon 2, Team
Tivoli 2026 - International Conference: The Harmony of the Two Worlds.
No full textScientific and institutional framework for the conference linking Second Brain Psychology (SBP) to UNESCO Heritage and Climate Resilience
Layered Working Framework for Cosciousness Research
No full textThis project presents a layered, operational framework for consciousness research that separates mechanism, interface, and definition across multiple analytic levels. Rather than proposing a new theory of consciousness, the framework offers a methodological working structure designed to bypass long-standing definitional disputes and enable cross-disciplinary integration.
The project includes a core framework paper, supplementary conceptual analyses, and simulation-based explorations developed iteratively. All materials are provided for open examination, extension, and reuse