Şırnak University

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    O AUTOCUIDADO NA FORMAÇÃO DE ESTUDANTES DE MEDICINA: SCOPING REVIEW

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    O presente estudo visa mapear as publicações sobre a avaliação do autocuidado entre estudantes de medicina. Espera-se que a avaliação apoie o desenvolvimento de currículos de graduação e incorpore a cultura de autocuidado entre futuros profissionais para uma melhor prática de autocuidado para si mesmos, seus clientes e a comunidade

    IJHS_Manuscript_Data_and_Code

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    This project contains supplemental material for an IJHS article. Contents include: -Description of all uploaded files -Data used in the study -Code used in the stud

    Closing the Execution Gap in Registered Reports: A Systems Analysis of Residual Reproducibility Failure Modes

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    This paper analyzes reproducibility failure modes that persist even under Registered Reports, including execution drift, unverifiable compliance, and lack of independent re-execution. It argues that these are not editorial problems but system-level issues requiring technical and governance infrastructure. The paper outlines requirements for closing the execution gap and describes an example architecture that satisfies them. The goal is to clarify what a future “RR 2.0” might require — not to pitch a specific platform

    When Artificial Minds Negotiate: Dark Personality and the Ultimatum Game in Large Language Models

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    Complete reproduction materials for "When Artificial Minds Negotiate: Dark Personality and the Ultimatum Game in Large Language Models." Includes experimental data from 17 open-source LLMs, human benchmarks, frontier models (GPT-4.1/5.1), and all analysis code. MIT License

    Post Hoc (Experiment 2)

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    This experiment aims to test whether counterfactual thinking affects participants’ causal and recommendation judgments when they commit the post-hoc fallacy. In Experiment 1, we found that people agreed more with the causal and recommendation statements in the improved condition relative to the unchanged condition. For Experiment 2, we revised all 15 vignettes from the improved condition in Experiment 1 so that they aligned with our planned manipulation. Each participant will view 1 vignette. Then, we will ask them to imagine an alternative to a background condition (background counterfactual condition) or describe what happened in the vignette (control condition). Finally, we will ask them to rate their agreement with a causal and a recommendation statement. We expect to observe lower agreement with causal and recommendation statements when they imagine an alternative to a background condition, as we observed in Pilot Experiment 2

    The Impact of Conditioned Expectations on Perception and Interpretation of Ambiguous Social Behaviors

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    Negative expectations about an event may shape the way it is experienced and interpreted. Prior work shows that aversive expectations can amplify the perceived unpleasantness and intensity of aversive stimuli, a process called aversification. The present study extends this research to socially relevant behaviors, investigating how conditioned expectations influence the perception and interpretation of ambiguous behaviors. To examine these expectation effects, behaviors in our study are operationalized using a set of verbs categorized as neutral, slightly negative, moderately negative, very negative or ambiguous based on the valence and ambiguity ratings obtained from a pilot study. By means of classical conditioning, these behaviors are differentially associated with two face identities serving as CS_negative and CS_neutral, respectively. During the acquisition phase, CS_negative is paired primarily with negative verbs (slightly negative: 20%, moderately negative: 30%, very negative: 20%) and also with neutral verbs (30%). CS_neutral is paired primarily with neutral verbs (70%) but also with slightly negative verbs (30%). In the test phase, both CS types are paired equally frequently with ambiguous verbs (50%). CS_negative is additionally paired with negative verbs (35%: slightly negative 10%, moderately negative 15%, very negative 10%) and neutral verbs (15%), whereas CS_neutral is paired with neutral verbs (35%) and slightly negative verbs (15%). This design allows us to assess whether prior expectations influence the perception and interpretation of ambiguous behaviors. We will collect and analyze subjective ratings of behavior unpleasantness and interpretation valence. We hypothesize that ratings of ambiguous behaviors will be more negative following CS_negative than CS_neutral. These findings will provide insight into the social dimension of aversification, exploring how expectations about a person’s behavior shape perception and interpretation of their actions

    CORE Outcome measure

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    Differentially expressed genes profiles of soybean seeds with contrasting seed coat color

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    a comprehensive transcriptome analysis was carried out to identify differentially expressed genes in seeds, naked seeds, and seed coats of black- and white-seeded soybean genotypes. By examining genes involved in metabolic pathways, hormone signaling, pigment biosynthesis, and transcriptional regulation, the study seeks to uncover key genetic determinants linked to seed coat composition, structural integrity, and longevity. Furthermore, this investigation intends to provide insights into regulatory networks governing seed quality traits and to establish a molecular foundation for future functional genomics and gene-silencing studies targeting improvement of soybean seed quality and storage performance

    Towards DNA-chromophore supramolecular assemblies for photon upconversion

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    The interactions of long DNAs of biological origin with small molecules have intrigued scientists for a while now, with particular emphasis on medical applications like cancer therapy. Recently, DNA’s unique highly ordered structures, selfassembly capabilities and ease of chemical modification have led to a more broad based approach for potential applications in photonic and electronic devices. In this thesis, we show that DNA can be used as a scaffold for supramolecular assembly of selected organic chromophores for tuning photon upconversion based on a triplettriplet annihilation (TTA) mechanism. Green-to-blue photon upconversion was observed using tris(bipyridine)ruthenium(II), [Ru(bpy)3]2+ as a long wavelength absorber and an insitu energy donor to an acceptor (R)-1-O-[4-(1- pyrenylethynyl)phenylmethyl]glycerol), abbreviated PEPy and also known as a twisted intercalating nucleic acid (TINA) monomer which acts as an annihilator and short wavelength photoemitter. This result prompted us to investigate interactions of the ligands ([Ru(bpy)3]2+ and ZnTMpyP4, the Zn2+ derivative of 5,10,15,20-tetrakis- (1-methyl-4-pyridyl)-21H,23H-porphine) with TINA moieties attached to a DNA scaffold. Zinc metallated porphyrins and ruthenium polypyridyl complexes are well known to act as donors in TTA-based energy upconversion. TINA-modified DNA duplexes and G-quadruplexes significantly improved the interaction between TINA and ZnTMpyP4/ [Ru(bpy)3]2+ as shown by fluorescence, circular dichroism (CD), and UV-Vis spectroscopy studies. In contrast to dynamic quenching of the TINA monomer fluorescence by [Ru(bpy)3]2+ and ZnTMpyP4 for free monomers in solution, ground state complex formation was the predominant mechanism of interaction between TINA-modified DNAs and [Ru(bpy)3]2+/ ZnTMpyP4. Energy upconversion was observed with a [Ru(bpy)3]2+ donor and TINA-modified DNAs. The results presented in this thesis lay a foundation for further energy upconversion studies utilizing appropriate organic chromophores using DNA as a scaffold

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