University of Pennsylvania

ScholarlyCommons@Penn
Not a member yet
    48670 research outputs found

    Collation Model for Ms. Codex 317: [Miscellany of theological, devotional and liturgical works]

    Get PDF
    Consists of miscellaneous theological, devotional and liturgical works including the Leggende (i.e. Vita e Miracoli) di S. Domitilla Vergine, which generally is the last portion of the Vita Nerei et Achillei (f. 1r-49r); 79 four-line stanzas that deal mostly with rules for proper behavior in daily, mostly secular, life (f. 51v-56v); the Lives and miracles of SS. Ursula and Elizabeth (f. 76v-95r); over forty sequences, readings, etc. used in the liturgy throughout the year (incomplete; f. 130r-228v); and various other short prayers and other works.https://repository.upenn.edu/sims_models/1067/thumbnail.jp

    Improving Residents’ Well-being Through Mindful Interventions and Character Strength Amplification

    Get PDF
    Abstract This paper offers a new approach that aims to improve the well-being of nursing home residents through implementing positive psychology. Developing care plans that include mindful practices as positive interventions may help improve cognition, mood stabilization, and amplification of character strengths. Specifically, residents engaging in the positive interventions may help improve their ability to live in the moment, while also learning to amplify certain character strengths as needed. Through improving mindfulness and learning to rely on their strengths, nursing home residents may become more self-sufficient during times of change. These care plans also inspire a sense of mattering within the facility because it shows the residents how much their care team values their well-being

    Owner Reported Outcomes on Two Psychometric Tests Do Not Predict Behavior on a Spatial Discounting Test.

    Get PDF
    Impulsivity is an inability to control inappropriate responses to stimuli in the environment. It refers to an inability to inhibit an action or to delay gratification for an immediate small reward versus a deferred large reward. Poor impulse control in dogs is a leading cause of owner relinquishment, rejection from assistance- and working-dog programs, and returns to shelter and foster care. The ability to reliably identify dogs who engage in impulsive behavior would improve these dogs’ welfare by facilitating appropriate interventions in a timely manner. To investigate if the tendency of impulsive choice could be predicted by available psychometric tests, twenty-four dog/handler teams were recruited to participate in this study. All teams were composed of veterinary professionals employed at a single community animal hospital and their dogs. Handlers completed both the Canine Behavioral Assessment & Research Questionnaire (C-BARQ) and the Dog Impulsivity Assessment Scale (DIAS) psychometric tests. All dog/handler teams then completed a spatial discounting test, assessing their dog’s ability to inhibit the choice of a close small food reward versus a more distant larger food reward. Twenty-one C-BARQ and DIAS sub-scales were found to have a statistically significant association. After performing a Bonferroni error correction calculation, two sets of pairwise associations related to arousability emerged as highly correlated and significant. However, we did not see a statistically significant association between C-BARQ, or DIAS sub-scales and maximum distance traveled in the spatial discounting test. This outcome raises the question of whether the attribution of impulsivity based on an owner reported questionnaire is subject to bias. Additionally, the spatial discounting test may not be an appropriate measure of impulsivity as a single test. The conclusion of this study suggests that veterinarians must carefully consider the limitations of behavioral diagnostic tests and be aware that erroneous results can influence welfare outcomes for companion dogs

    Efficacy of Lidocaine Topical Solution in Reducing Discomfort Reaction to Intramuscular Vaccination of Horses

    No full text
    Administration of vaccinations via intramuscular injection is a key component of preventative medical care in horses, but development of problematic behavioral aversion to injections is quite common. It has been our clinical impression that the application of a topical anesthetic prior to vaccination may provide a simple means to reduce discomfort associated with the procedure and the resulting behavioral reactions. However, this had not been critically tested. To blindly evaluate efficacy, 78 ponies were divided into three treatment groups, each treated with either 0% control, 5%, or 10% topical lidocaine solution applied two minutes before intramuscular vaccination. Reaction scores for both the 5% and 10% lidocaine-treated groups were significantly lower than the control group. Additionally, the proportion of subjects with a reaction score greater than 1 was 2 of 25 for the 5% lidocaine solution, 5 of 26 for the 10% lidocaine solution and 15 of 27 for 0% lidocaine control. For both the 5% and 10% lidocaine solutions, the proportion differed significantly from control. The difference between the 5% and 10% lidocaine groups was not statistically significant. These findings confirm our clinical impression that application of topical anesthetic just two minutes in advance of injection can effectively reduce discomfort behavior reaction of horses

    Toward a New Framework for Companion Animal Healthcare Services at the Community Level

    Get PDF
    An estimated 2 million or more companion animals every year are surrendered to shelters in the United States by their “pet parents” for a variety of reasons. The literature on companion animal surrender indicates that such relinquishments occur for owner-related and/or animal-related reasons. Research suggests that human housing issues are closely related to pet relinquishment, that animal behavioral issues are a frequent reason for surrender, and that pet healthcare needs and expenses are often associated with animal surrender. Many of the reasons for surrendering a pet, and especially those related to human housing, animal behavior, and pet healthcare expenses, are potentially connected with financial constraints. If assistance and support were available to “pet parents”, through the public and/or the private sector, it is likely that the incidence of pet surrender could be reduced. Existing programs at both the animal shelter level and the broader community level do offer assistance and, especially with respect to pet healthcare needs, certain veterinary services are brought into some underserved communities. This paper explores barriers to receiving companion animal healthcare services and options to structuring in-community veterinary care services, proposing that animal health services be actually embedded within the community instead of brought into the community. The proposed community-embedded animal health model is based upon a “pyramid” structure for animal health services, moving upward from neighborhood pet healthcare “hubs” through local clinics and community hospitals. Similarly, a “pyramid” structure for staffing, designed to address care accessibility barriers including communication challenges and diversity within the allied veterinary professions, would be built upon a foundational level of a cadre of local community animal health workers. Also contemplated is enhanced utilization of veterinary technicians/nurses, as well as creation of a new midlevel veterinary professional role, under the direction and supervision of a licensed veterinarian. I predict that the incidence of pet surrender due to financial-related challenges would decrease as a result of community-embedded multi-level support for pet healthcare

    A New Clinical Use Of Catalytic Iron Oxide Nanoparticles For Endodontic Treatment

    No full text
    Ferumoxytol (Fer) is an Iron oxide nanoparticle formulation (IONP) that have been FDA-approved for systemic administration to treat iron deficiency anemia. Several IONP formulations have been approved for different biomedical applications including MRI, drug delivery and anti-inflammatory treatment. Moreover, IONPs exhibit strong catalytic activity that mimic natural horseradish peroxidase enzyme, which has shown therapeutic activity including prevention of tumors and infections. Many infectious diseases are caused by and associated with biofilms, including endodontic infections. The reduction or elimination of microorganisms has been associated with positive endodontic outcomes and is the basis for prevention and treatment of endodontic disease. However, conventional antimicrobial agents fail to completely eliminate bacterial biofilm within the root canal system. Here, we show that ferumoxytol nanoparticles (an FDA-approved formulation of iron oxide nanoparticles) are a potent antibiofilm agent and an effective endodontic irrigation solution for disinfection of the root canal system. Ferumoxytol (Fer) displays catalytic activity similar to peroxidase at acidic pH to activate hydrogen peroxide (H2O2) to release antimicrobial free v radicals to eradicate endodontic biofilms. Further analyses revealed that Fer nanoparticles can bind to biofilm and maintain their catalytic activity in situ. Notably, Fer/H2O2 topical therapy demonstrated enhanced antimicrobial activity in comparison to a standard of care solution (NaOCl) against ex vivo mixed-species biofilm. Furthermore, Fer/H2O2 was effective against endodontic infections in patients diagnosed with pulp necrosis and apical periodontitis with no reported adverse effects. Intriguingly, Fer nanoparticles were devoid of cytotoxic effects on stem cells of the apical papilla (SCAPs). Altogether, Fer nanoparticles are a potent and biocompatible antibiofilm agent in both laboratory and human studies, demonstrating promising therapeutic potential as a novel disinfection approach. Our data show a promising yet translatable therapeutic platform based on iron oxide nanoparticles that could have immediate clinical applications to combat endodontic infections and other oral biofilm disease

    Variation in Path Encoding in Motion Events in Toronto Heritage Cantonese

    Get PDF
    This study examines path encoding in motion event expression in Toronto Heritage Cantonese using a variationist sociolinguistic methodology informed by studies on the typology of motion events (Talmy 2000). Cantonese inherently exhibits some variability in that both satellite-framing and verb-framing strategies of path encoding are grammatical and natural (Yiu 2014). Work on motion events in bilinguals suggest that typologically different languages may have crosslinguistic effects on motion event expression (Filipović 2011, Brown and Gullberg 2008, Wang and Wei 2019, among others). In light of this body of work, I investigate the linguistic and social factors that are relevant to the variation seen in Toronto Heritage Cantonese and Hong Kong Cantonese, the homeland variety. Spontaneous speech from 23 sociolinguistic interviews from the Heritage Language Documentation Corpus (Nagy 2011) is analyzed by extracting all relevant examples of motion event expression (n = 1991). Intergenerational and diatopic comparisons are made using comparative variationist methods. The results suggest stable variation in the homeland speakers, but change among the heritage speakers, which cannot be attributed to simplification or contact with English

    A Social Meaning Perspective on Vowel Trajectories: The FEEL-FILL Merger among African Americans

    Get PDF
    Studies have shown that fine-grained phonetic details play an important role in signaling linguistic contrasts (Labov et al. 1991, DiPaolo and Faber 1990). Listeners are attuned to differences in duration (Bailey 2001, Thomas 2001), phonation type (Yaeger-Dror and Thomas 2010), and monophthongization and diphthongization (Kohn 2013). That listeners are attuned to each of these cues provides evidence that many differences in sound can be used to convey phonological distinctiveness and preserve contrasts in the linguistic system. I show that distinction in the FEEL-FILL merger is maintained by vowel contours and that, furthermore, contour emerges as socially indexical. Analysis of 24 African Americans from Bakersfield and Sacramento, California shows that African American men merge FEEL and FILL such that F1 is diphthongal and overlapping throughout the rhyme for both vowel classes while African American women maintain a distinction with a relatively flatter FILL F1 contour. Additionally, younger African Americans and African Americans with higher levels of education have a relatively flatter FILL contour. Whereas a diphthongal FILL is in alignment with the Southern Vowel System, a monophthongal FILL is aligned with California English. Thus, the gendered pattern is located within a pattern of change in which women are leading a change away from the Southern pattern in part due to an emphasis on respectability and social mobility. These findings demonstrate that the vowel contour can be distinctive and carry social meaning, as well

    Ideologies of Intelligibility Onscreen: The Sociolinguistics of Intralingual Subtitling

    Get PDF
    Intralingual subtitling—specifically, translation of audio in one language into non-optional text of the same language—can be used when a speaker’s dialect is considered difficult for target audiences to understand. Thus, these subtitles and the commentary surrounding them offer insights into ideologies of within-language intelligibility. In the present study, we investigate such ideologies from two approaches: by documenting how intralingual subtitles are being used in practice in two reality-based, US cooking shows, and by looking at published complaints about intralingual subtitles (primarily in US/UK English contexts). We find more subtitles for L2-English vs. L1-English speakers in the shows, and metacommentary around subtitling similarly suggests that L1-English subtitling is perceived as more salient and offensive, reflecting broader associations of unintelligibility with non-native speech. The use of subtitles for L1 English outside of noisy environments appears to be limited to certain varieties, such as Scottish or Indian English, suggesting that some L1 varieties of English can be acceptably codified as unintelligible. While the purpose of intralingual subtitles is ostensibly to facilitate communication and have been framed in the literature as tools for breaking down boundaries, both the practice and commentary around these subtitles highlight the largely negative connotations of marking someone as unintelligible

    L2 Decay Of Certain Bilinear Oscillatory Integral Operators

    Get PDF
    In this thesis, we study bilinear oscillatory integral operators of the form Iλ(f1,f2)=MeiλΦ(x)f1(x1)f2(x2)a(x)dσ(x) I_\lambda(f_1, f_2) = \int_M e^{i\lambda \Phi(x)} f_1(x^1) f_2(x^2) a(x) d\sigma(x) where x1:=(x1,,xd)x^1:= (x_1, \dots, x_d), x2:=(xd+1,,x2d)x^2:= (x_{d+1}, \dots, x_{2d}), and ρ,Φ,a\rho, \Phi, a are smooth functions on an open box B1B_1 with aa compactly supported, iρ\partial_i \rho nonvanishing on B1B_1 for each ii, and M:={xB1ρ(x)=0}M := \{ x \in B_1 \,|\, \rho(x) = 0\}. Under an additional determinant condition that has similarities to both a mixed Hessian condition on Φ\Phi and a Phong-Stein rotational curvature condition on ρ\rho, we prove that this operator has optimal L2L^2 decay, namely that Iλ(f1,f2)Cλd12f1L2(Rd)f2L2(Rd) |I_\lambda(f_1, f_2)| \leq C|\lambda|^{-\frac{d-1}2} ||f_1||_{L^2(\mathbb{R}^d)} ||f_2||_{L^2(\mathbb{R}^d)} The proof uses a frequency space decomposition which is a higher-dimensional analogue of one developed in earlier work with Gressman, and applies this to the functions f1f_1 and f2f_2 to generate a kernel which captures the oscillatory behavior of the phase and can be analyzed using stationary phase arguments, among others. The constant CC in the bound depends continuously on parameters based on a,Φ,ρa, \Phi, \rho, the dimension dd, and the size of the support of the integrand, and so the result is stable under small perturbations of these objects. We then study two specific bilinear operators which have polynomial phase, and show how the results of the main theorem can be leveraged to prove decay even when the determinant condition in the hypothesis does not hold. We also use these examples to show that the decay of the operator is affected by the precise way in which the determinant condition fails

    28,487

    full texts

    48,670

    metadata records
    Updated in last 30 days.
    ScholarlyCommons@Penn
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇