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Body composition assessment in patients with spinal cord injury by bioimpedance
Background: Individuals with spinal cord injury develop alterations in the metabolism of carbohydrates and lipids, chronic inflammation, abnormal control of glycemia, as well as loss of lean mass, and increased adiposity, these being some risk factors for the development of diseases and decreased quality of life. This research aimed to investigate the body composition during a treatment protocol with NMES in a spinal cord injured population. Methods: An initial bioimpedance evaluation using Biodynamics 310e was performed on 19 spinal cord injury patients. During the following 4 months, they received neuromuscular stimulation. The individuals ended the clinic once a week and performed NMES for 45 min, 20 min on quadriceps, and 15 min on peroneal nerve, on both legs with a frequency in the range of 18 to 25 Hz. A new bioimpedance test was performed after this period. Results: For data analysis, a 5% significance level was considered. There were statistically significant gains in lean mass with p= 0.0001 and a decrease in bio-strength with p= 0.0457. There was a loss of body fat, but not significant. Conclusion: Individuals with spinal cord injury showed measurable body composition changes during a four-month neuromuscular electrical stimulation treatment.</p
Adsorption of Pb2+ ions in aqueous media using the new zeolite nanocomposite adsorbent CaOCdO/ZSM5 synthesized with new techniques
ZSM-5 `is a porous zeolite material that reveals good activity for the adsorption of heavy metals and other contaminants for effluent purification. In this scientific research, we synthesized the novel CaO-CdO/ZSM-5 zeolite nanocomposite adsorbent and studied the effects of different parameters on the adsorption of Pb2+ ions from water media for the first time. About 99.2% adsorption removal efficiency was obtained after a contact time of 60 min and an adsorbent amount of 0.1g/L for an initial Pb2+ concentration of 200mg/L at pH 8 and temperature of 60oC. The adsorption kinetic fit well via the pseudo-second-order model. Furthermore, the adsorption results were reproduced using the Langmuir isotherm with a maximum adsorption capacity of mg/g. The thermodynamic data displayed that the adsorption of Pb2+ ions over the CaO-CdO/ZSM-5 nanocomposite was endothermic and spontaneous. </p
The new Dysfunctional Personality Model of the Anxiety Matrix (DPM-AM): “Neurotic Personality Disorder” (NPD)
Background and objectives: According to the PICI model, second edition, the personality disorders of the neurotic area are six (anxious, phobic, obsessive, somatic, avoidant, and manic) and the diagnosis of the psychopathological disorder is determined on the basis of the persistence of certain dysfunctional traits present in the personality framework. However, on the basis of clinical experience and through the application of IPM/PICI, Deca, PDM, PHEM, and PPP-DNA models (including PF-SPEM and NDAM), it was found that all the disorders of the neurotic area had in common the anxiety traits and that the symptoms of the six different disorders were often present in comorbidity. This assumption led to the hypothesis that there was a different and better way to group them into a single, all-encompassing category: “neurotic personality disorder”. This research aims to demonstrate whether or not
<td height="20" class="xl66" align="right" width="130" style="height:15.0pt;
width:98pt">9484147895 the use of this hypothetical new nosographic construct is useful.Materials and methods: Individual clinical interview, consisting of the amnestic collection and administration of the PICI-2TA (Perrotta Integrative Clinical Interviews, version 2-TA), PAD-Q (Perrotta Affective Dependency Questionnaire), PSM-1 (Perrotta Sexual Matrix) and PDM-Q (Perrotta Defence Mechanisms Questionnaire), to each group of population.Result: Of the selected sample of 326 subjects, 318 were eligible because they met the inclusive criteria. The three male groups, subdivided by age (18-36, 37-54, 55-72), completely resolved their neurotic symptoms in 86.7% (13/15), 87.5% (7/8) and 60% (3/5), for a partial total of 78.1% (23/28), while the remaining 21.9% (5/28) declared to have benefited from the PPP-DNA protocol with an attenuation of at least 50% of their neurotic symptoms. The three female groups, subdivided according to age (18-36, 37-54, 55-72), completely resolved their neurotic symptoms in 93.3% (154/165), 95% (57/60), and 92.3% (60/65), for a partial total of 93.5% (271/290), while the remaining 6.5% (19/290) declared to have benefited from the PPP-DNA protocol with at least a 50% attenuation of their neurotic symptoms. Conclusion: The PPP-DNA protocol is effective for 85.8% (with a greater prevalence of effectiveness in the female population) in the resolution of neurotic symptoms of anxious, phobic, somatic, avoidant, obsessive, and manic nature, both with the previous wording and with the new nosographic hypothesis “neurotic personality disorder”, as it does not represent a new psychopathological construct but only a different way of grouping disorders of cluster A (neurotic) to avoid that the absorptions do not take into account important dysfunctional traits that are instead at the base of those disorders and therefore does not affect in any case the exact diagnosis of the dysfunctional personality profile.</p
The clinical boundary between deviant behavior and criminal conduct: From maladaptive positions to pathological dysfunctionality using the “Graded Antisociality Model” (GA-M), the “Antisocial Severity Scale” (AS-S) and “Perrotta-Marciano questionnaire on
The concepts of deviance and criminality are often confused or grouped, following a sociological logic. In the clinic, there is a need to distinguish them, speaking of “deviant behaviors” as active human acts that result in a violation of a social norm determined by the community and that do not provide a sanction of a legal nature (e.g., personal use of drugs)”, while from “criminal behaviors” as active human acts that result in a violation of an exclusively legal norm and that provides a sanction of a civil-administrative nature (compensation for damages, restitution, demolition, suspension, disbarment, and administrative detention) or criminal (fine, fine, imprisonment and arrest)”. Even more succinctly, we can consider “deviant and criminal behavior” (DCB) as all those active human acts that constitute a violation of a social and/or legal rule, and their transgression provides for the application of a punitive sanction. Based on this assumption, we propose a) the Graded Antisocial Model (GA-M), which considers antisociality as a graded phenomenon that is reinforced over time through active behaviors that are not limited by the social context of reference, becoming then a structured personality disorder only when the individual’s self-centeredness becomes rigid and dysfunctional; b) the Antisocial Severity Scale (AS-S), which draws the pathological and dysfunctional evolution of antisociality, in five levels (yellow for emotional dysfunctionality, orange for self-centeredness, red for violation of social rules and violence to property, animals, and people, purple for severe violation of legal rules and black for structured psychopathology); c) the Perrotta-Marciano Questionnaire on the state of awareness of one’s deviant and criminal behaviors (ADCB-Q), in 30 items on L1-6 scale, which defines both deviant and criminal tendency and the grade of awareness of one’s pathological state.</p
A multicomponent program improved cognitive and physical functions of older adults with lower GDS values
Background: MCI is an intermediate stage between cognitive impairment status and persons with MCI are at high risk of developing AD. This study aimed to investigate the effects of a multicomponent program (aerobic, resistance exercises, cognitive training, music, myofascial release exercises, acupoint stimulation, and oral gymnastics) on the cognitive and physical functions of older adults in community dwellers and it is to clarify which measurement factors are predictive to reverse MCI to normal.Results: In this study, we measured cognitive functions, physical functions, and the diagnosis of MCI. We assessed factors before (pre-test), and after treatment of 12 training sessions (post-test). The participants were divided into two groups (Improve group and the Non-Improve group). The Mann-Whitney test was used to analyze the differences between pre-and post-test and revealed significant differences in the UWS (p < 0.05), WM (p < 0.01), SDST (p < 0.01), and MMSE (p < 0.01). Moreover, binomial logistic regression analysis revealed a significant association of the Improved group with the GDS-15 (Odds ratio, 0.587; 95% Confidence Interval [95% CI], 0.309-0.791; p = 0.003) and MMSE (Odds ratio, 0.494; 95 % CI, 0.360-0.957, p = 0.033). Conclusion: This study indicated that this program improved physical and cognitive functions in those who were not prone to depression before treatment and suggests that the GDS measurement might be able to predict the intervention effects of a multicomponent program.</p
Effect of Fungicide Application Rate and Frequency on development of Major Faba bean Diseases, Grain Yield and Yield Components of Faba Bean (Vicia Faba L.) at Southeastern Oromia, Bale
The experiment was conducted at Sinana and Agarfa to determine the application rate and frequency of MATICO. Randomized Complete Block Design with three replications was used to lay out the experiment. Logistic model (ln[y/ (1-y)]) was used to estimate r. Correlation and regression analysis were employed to find the relationship between diseases’ severity, yield, and yield-related traits. Analysis of Variance (ANOVA) for diseases parameters has shown significant differences (p<0.05) between treatments. The highest diseases parameters were recorded from unsprayed and plots sprayed with lower rates and frequency and the lowest was recorded from plots sprayed four tines at 2.5 kg/ha. ANOVA for yield and yield-related traits has shown significant variations (P<0.05) among treatments. The highest pods per plant (21), thousand Kernel Weight (664.7g), and grain yield (3319.4kg/ha) were recorded from plots sprayed four times at 2.5 kg/ha. Simple linear regression has revealed a significant association (P<0.0001) between grain yield and diseases severity and the Correlation of grain yield with diseases severity has depicted a significant negative correlation. The highest marginal rate of return (2126.31%) was obtained from plots sprayed twice at 2.5kg/ha. Therefore, two times application of MATICO WP at a rate of 2.5 kg/ha is recommended.</p
The sweet potatoes new genotypes introduction in Ukraine
Aim: Conduct research on the collection of new genotypes of sweet potatoes introduced under growing conditions in the Kharkiv district of Ukraine.Results and discussion: In the conditions in the Kharkiv district of Ukraine, an assessment was made of 13 genotypes of sweet potato a domestic and foreign selection. The genotypes were very different in length of the growing season, biometric parameters of plants, and productivity. The studied genotypes were divided into three ripeness groups. Samples that characterized the three groups - early ripening: V-1, V-6, А-7, В-4; medium ripening: Оr-3, D-2, М-8; late-ripening: B-9, P-11, B-10, J-12, Е-5, Оk-14. A wide range of shapes was obtained along the length of the stem. All genotypes that entered the mid-ripening group formed long, climbing stems. So, plants of the genotype Or-3 formed long stems similar to vines, 214 cm long. The genotypes of the early ripening group were characterized by lengths from 144 cm (V-6) up to 153 cm (А-7). According to the “Quantity of additional shoots” attribute, the variability range was 4–8 cm, and the coefficient of variation was 17%. Significant variation was observed along the length of the internodes (V = 30%). The variability range was 4.39–9.97 cm. According to the “Quantity of leaves” characteristic, the variability range was 40–77 pcs. And the coefficient of variation was 20%. The genotypes of the middle ripening group that had the largest “Quantity of leaves” were 77 pcs./plant (Оr-3) and 71 pcs./plant (D-2). The smallest was 40 pcs./plant (B-10), 42 pcs./plant (B-9), 44 pcs./plant (P-11). The root tubers in genotype V-6 had an oval shape, smooth peel, and pink color. The flesh was a creamy solid color; it was a sample of sweet potato. The shoots were long, climbing, leaves of a dark green color without anthocyanin color, kidney-shaped. The genotype of sweet potato D-2 of Ukrainian selection was a dessert variety. The tubers of the genotype were elliptical, orange with a smooth peel; the flesh was firm and bright orange. The shoots of the plants were very long, very climbing, and light green. The shoots of the leaves were kidney-shaped, light green. The results showed that table genotypes are of greater value for dietary nutrition. Dessert genotypes are conducive to a variety of diets for people with diabetes. A list of genotypes that can be used by people who follow a diet has been provided.Conclusion: In the conditions in the Kharkiv district of Ukraine, 13 introduced genotypes of sweet potato domestic and foreign breeding were evaluated. They already discovered that the genotypes were different in the growing season by biometric parameters of plants and yields. By using clonal selection in vitro culture, two completely new promising genotypes of domestic selection of sweet potatoes V-6 and D-2 were obtained. Tubers of genotype V-6 were oval, skin smooth, and pink. The average weight of one was 351 g. The raw flesh was cream-colored. Long shoots were woven, their length was 144 cm; the leaves were dark green, and kidney-shaped. Another example of a domestic selection of sweet potato D-2 was a dessert type. The root tubers were elliptical and had an orange color with smooth skin. The average weight of the tubers was 410 g. The raw flesh was a solid bright orange color. Shoots were extremely long -198 cm, very creeping, and had a light green color. The leaves were kidney-shaped and light green.</p
Search for the dispatch schedule optimal configuration for managing releases of the complex “Lake Baikal - Irkutsk Reservoir”
The article considers methods for constructing optimal (in the Pareto sense) coordinates of the dispatch schedules for managing releases for the water management complex “Lake Baikal - Irkutsk Reservoir”. Statistical reliability criteria such as the number and depth of violations are used as optimization criteria. The construction of the optimal dispatch schedule is carried out based on water resource calculations for long-term hydrological inflow series from 1903 to 2016 (the number of the periods per year is 24) and modern hierarchically ordered requirements of water users. Since the water users’ requirements, as a rule, conflict with each other, a multi-criteria analysis of various optimal dispatch schedules were used to find the optimal Trade-off solution. To search for the optimal configuration of the dispatcher, the author’s methods of local optimization were developed, which allow solving a complex non-linear programming task in a reasonable time. Software for water resource calculation and optimization was developed with the VBA language in the Excel environment. </p
Contrary to expectation: Preserved renal function after using PD-1 Inhibitor Cemiplimab-rwlc in a kidney transplant recipient
The use of immune checkpoint inhibitors in transplant recipients with malignancy is associated with the risk of graft failure due to acute rejection. There is limited literature regarding the use of Cemiplimab-rwlc (Libtayo) in kidney transplant patients. Here we present a case of using Cemiplimab-rwlc (Libtayo), a Programmed Death receptor-1 (PD-1) blocking antibody for locally advanced and metastatic Cutaneous Squamous Cell Carcinoma (CSCC), in a kidney transplant recipient.</p
Drilling speed-up and production-increasing development practice of ultra deep clastic reservoir based on Geology-Engineering integration in the Tarim Basin, Northwest China
Kelasu structural belt in Tarim Basin has a large reservoir burial depth and complex geological conditions, and challenges such as ultra-deep, high temperature, high pressure, and high stress lead to big problems related to well control safety and project quality. To solve these key technical problems that set barriers to the process of exploration and development, a set of drilling technology processes via geology-engineering integration is established with geomechanics as the bridge. And an integrated key drilling engineering technology for the safe speed-up of ultra-deep wells was formed, integrating well location optimization, well trajectory optimization, stratum pressure prediction before drilling, stratum drillability evaluation, and bit and speed-up tool design and optimization. Combined with seismic data, logging data, structural characteristics, and lithology distribution characteristics, the rock mechanics data volume related to the three-dimensional drilling resistance characteristics of the block was established for the first time, and the vertical and horizontal heterogeneity was quantitatively characterized, which provided a basis for bit design, improvement, and optimization. During the process of drilling, the geomechanical model shall be corrected in time according to the actual drilling information, and the drilling “three pressures” data shall be updated in real-time to support the dynamic adjustment of drilling parameters. Through field practice, the average drilling complexity rate was reduced from 18% to 4.6%, and the drilling cycle at 8500 m depth was reduced from 326 days to 257 days, which were significantly better than those of the vertical wells deployed in the early stage without considering geology-engineering integration.</p