University of South Alabama Institutional Repository
University of South Alabama Institutional RepositoryNot a member yet
5383 research outputs found
Sort by
Effects of Personality Type on Cochlear Implant Use, Quality of Life, and Perceived Auditory Experience
Prior audiologic research suggests that the personality traits of cochlear implant (CI) users likely influences their rehabilitation. Research has primarily focused on the “Big Five” personality domains (Agreeableness, Extraversion, Conscientiousness, Negative Emotionality, and Open-Mindedness) with limited information available on the underlying facets. The aim of this study was to better understand how personality domains and facets were related to CI user’s quality of life, barriers to CI use, and perceived hearing ability. Twenty-six adult CI users completed an online survey which included a demographic questions and a series of questionnaires: the Cochlear Implant Use Questionnaire (CIUQ), the Cochlear Implant Quality of Life (CIQOL-10), and the Speech, Spatial, and Qualities of Hearing Scale (SSQ12). Results revealed that quality of life in CI users was associated with extraversion traits (sociability and energy level) and that perceived hearing ability was correlated with a CI user’s level of self-reported responsibility and depression
Cell Type-Specific Production of Amyloid Precursor Protein During Infection is Dependent on the Strain of Herpes Simplex Virus 1
Cleavage of amyloid precursor protein (APP) generates the antimicrobial peptide amyloid beta (Aβ), the accumulation of which is linked to Alzheimer’s Disease (AD) pathogenesis. Whether processing of APP contributes to anti-viral responses is debated. Herpes Simplex Virus Type 1 (HSV-1), a neurotropic double-stranded deoxyribonucleic acid (DNA) virus, establishes lifelong latency and can cause a range of outcomes, from asymptomatic infection to herpetic encephalitis (HSE). Whether disparate outcomes are dependent on HSV-1 strain is unknown. Using three differentially virulent HSV-1 strains, we compared the regulation of APP-associated proteolytic processing in both a corneal infection murine model and an in vitro model. By single-cell RNA-sequencing on infected cornea, and by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) on infected corneal fibroblasts, we observed that transcripts of APP, presenilin-1 (PSEN-1), and γ-secretase activating protein (GSAP) were elevated in less neurovirulent strains of HSV-1 relative to the most neurovirulent strain. Furthermore, processing of APP to Aβ was increased in cells infected with less neurovirulent HSV-1. Taken together, these data are consistent with a model whereby APP production and processing shapes neurovirulence of HSV-1
Examination of Sex-Differences in Neuromuscular Function Following Acute Bouts of High- and Low-Load Resistance Exercise
High-load resistance training (\u3e70% 1 repetition maximum (RM)) is commonly believed to be the superior method for producing neuromuscular adaptation with a resistance exercise program. Recent research has shown that lower-load resistance training (\u3c50% 1RM) could produce similar responses when taken to failure. However, nearly all the existing research has been completed in males, making it unclear if this holds true across sexes. The purpose of this investigation, therefore, was to examine sex-differences in neuromuscular function and fatigue following acute bouts of high- vs low-load unilateral leg extension taken to volitional failure. Twenty-nine (16 females) resistance-trained subjects completed unilateral high-load (HL) and low-load (LL) resistance exercise bouts. The condition and leg utilized for the first visit was randomized and the opposite condition was completed on the other leg 24 hours (±1 hr.) after the first session. Surface electromyography (EMG) of quadriceps, exercise performance, and rating of perceived exertion (RPE) were measured during each visit. The present data suggests a more pronounced accumulation of fatigue in the muscle throughout LL, as indicated by greater reductions in repetitions completed with each set and more pronounced reductions in EMG median power frequency (EMGMDF). Despite similar patterns of EMG amplitude (EMGAMP) across the exercise bouts, the present data suggest that HL produced significantly greater muscle excitation than LL when collapsed across all other factors. Overall, males completed more repetitions across sets and during each condition when compared to females. Consequently, males also reported a greater set RPE/repetitions in reserve (RPE/RIR) and session RPE (sRPE)
META Project: Construction, Validation, and Flight Testing of a New META Aircraft Design
Meta aircraft are a type of aircraft that can connect via wingtip, nose-to-tail, or both wingtip and nose-to-tail in order to create a lattice of aircraft that can fly together to a site, detach, survey different areas, and then reattach for flight back to the main base. The project started at the Georgia Institute of Technology with Dr. Carlos Montalvo and is being continued at the University of South Alabama Facility for Aerospace Systems and Technology Lab. This paper seeks to theoretically verify the new aircraft design for the META project, complete the development of the design, and to experimentally test the design for validation for future development of the project
The Tripartite Influence Model of Body Image and Disordered Eating among Female Athletes: Testing an Expanded Model
The aim of the study was to investigate how different sources of sociocultural pressure (family, media, peers) described in the Tripartite Influence Model, and additions of teammate- and coach pressures, were associated with thinness-and muscularity internalization and appearance comparisons among athletes. Subsequently, these potential mechanisms were explored as predictors of disordered eating among athletes. Analyses included 71 female athletes. Athletes were recruited through a student subject pool recruitment portal, as well as with local and regional flyers and emails. Participants completed a series of self-report measures in Qualtrics. Hierarchical linear regression analysis was utilized to test the hypotheses. Partial support for the Tripartite Model was found. Results indicated that media pressures were significantly associated with thin ideal internalization and appearance comparisons. Teammate and coach pressures were not associated with ideal internalization or appearance comparisons. Significant associations were found between athletic ideal internalization and engagement in excessive muscle building and exercise behavior. Significant associations also were found between appearance comparisons and binge eating. This research helps highlight the importance of developing targeted interventions for athletes, with particular attention to the media, thin- and athletic ideal internalization, and appearance comparisons
DNA Methylation of the AGTR1 Gene in a Hypertensive Population of Kenyans
Cardiovascular disease (CVD), the leading cause of death worldwide, is rapidly increasing in low-and middle-income countries (LMICs), particularly those of Sub-Saharan Africa (SSA)(World Health Organization). Hypertension is the leading risk factor for CVD and is a multifactorial disease with no single genetic cause. Increasingly, evidence indicates that hypertension is predisposed by environmental regulation of genes through heritable, yet modifiable, epigenetic changes to DNA leading to changes in gene expression, e.g. methylation. While understanding the etiology of hypertension in LMICs is a global priority, few epigenetic studies exist from populations living in SSA (Fan). The renin-angiotensin system (RAS) is the primary hormonal pathway that regulates blood pressure through changes in salt and water retention. Previously, we have found a high prevalence of hypertension (55 % had systolic blood pressure (SBP) \u3e130 mmHg) in a rural population of Kenyans that was not correlated with lifestyle or behavioral factors (Williams).https://jagworks.southalabama.edu/honors_college_posters/1026/thumbnail.jp
USA Archaeology Museum Newsletter - April, May, and June 2024
In this edition of the museum\u27s newsletter: On Exhibit Until Friday, May 2, at the Archaeology Museum: Unwritten: Archaeology & Oral History of Jim Crow Mobile. Documenting the Africatown Cemetery Volunteer Opportunities: Watch Documenting the Historic Plateau/Africatown Cemetery by Alexandria Jones, Ph.D. Exhibit Opening: Growing Up Down The Bay, April 26-May 31 at the Ben May Library. Delta Woods & Waters Expo at the 5 Rivers-Alabama Delta Resource Center Archaeology Video Game: Bijou Black History Underground Migration on the Delta Upcoming Exhibit: Now Accepting Submissions for the INTO Light Project Alabama Archaeological Summer Meeting & Florida Anthropological Society 76th Annual Meeting hosted by the Pensacola Archaeological Society Giving to the Archaeology Museu
Conversations to Find One’s Truth: Coaching in Medical Student Education
Following coach training for College of Medicine faculty and leadership, the benefits of coaching for inculcating the habit of self-reflection to find one’s truth and create learning paths was recognized. While there was unanimous agreement to implement coaching for medical students, the contributing factors for the success of or barriers to academic medical coaching programs were ambiguous. We embarked on a scoping review to understand how coaching is being used for medical learners, and will share our process and preliminary discoveries.https://jagworks.southalabama.edu/cotl2024-talk/1003/thumbnail.jp
A Thorn in Spain\u27s Side
A Thorn in Spain\u27s Side: The Rise & Fall of 16th Century French Huguenot Corsairs, an Alliance Française Lecture with Jen Knutson Before the Age of Piracy, French Huguenot Corsairs used their wealth and influence to rise in rank to lead the French navy and advance to the French nobility, only to lose it all and be expelled from France in the next century. Jen Knutson is the Assistant Director of the University of South Alabama Archaeology Museum in Mobile, Alabama (B.A., University of North Florida) and president of the Alabama Archaeological Society, Southwest Chapter and the Florida Anthropological Society. Jen is also a Project Archaeology certified Master Teacher and public archaeologist. Originally from north Alabama, she has excavated sites across northern Florida from St. Augustine to Pensacola, including work on her current M.A. thesis research at the University of West Florida on the French Huguenot Colony of Campbelltown in British West Florida
Where is the parity: Exploring the gap between health disparities and health equities
The University of South Alabama Archaeology Museum hosted speakers from the Whiddon College of Medicine at 3:30 p.m. Wednesday, April 3, 2024. Franklin Trimm, M.D., assistant vice president for medical affairs and associate dean for diversity and inclusion, and Tiquera Hall, M.P.A., education and training specialist in the Office of Diversity and Inclusion, will present Where is the Parity: Exploring the Gap Between Health Disparities and Health Equities