OpenWorks @ MD Anderson
Not a member yet
    4211 research outputs found

    Management of Small Early-stage HER2-positive Breast Cancer: Trends and Outcomes

    Get PDF
    https://openworks.mdanderson.org/sumexp23/1056/thumbnail.jp

    Fred Flintstone Automobile, 2023

    No full text
    Artist: Oscar G. Rangel Materials: Recycled copper tubing and air dryers from laboratory refrigeration equipment.https://openworks.mdanderson.org/recycledart2023/1012/thumbnail.jp

    Heterogeneous vs Heterogenous

    Get PDF
    https://openworks.mdanderson.org/word2023/1006/thumbnail.jp

    From Pathology to Radiology: Bridging the Gap Using Artificial Intelligence

    Get PDF
    June 05, 2023 Mirabela Rusu, PhDAssistant Professor, Department of Radiology; Director, Personalized Integrative Medicine Laboratory at Stanford Universityhttps://openworks.mdanderson.org/igct_seminars/1000/thumbnail.jp

    From Bench to Bedside: Surgical Margin Assessment using Machine Learning and Mass Spectrometry

    Get PDF
    December 08, 2023 Parvin Mousavi, PhDProfessor, Department of Electrical and Computer Engineering at Queen’s Universityhttps://openworks.mdanderson.org/igct_seminars/1007/thumbnail.jp

    Meta-Narrative Review of PD-L1 by immunotherapy on Triple-Negative Breast Cancer

    Get PDF
    Triple-negative breast cancer (TNBC) is an aggressive form of subtype breast cancer and there are currently new treatments being discovered such as the combination of immunotherapy and chemotherapy. In immunotherapy against triple-negative breast cancer, checkpoint inhibitors like PD-1/PD-L1 treat TNBC by blocking the “off” signal that prevents T-cells from killing cancer cells. As a group, we conducted a meta-narrative review collecting results from primary sources such as clinical trials and human experimental studies to support our research question on how PD-L1 inhibitor treatments compare to other treatments in patients with TNBC. The review included articles searched from Embase, Pubmed, EMBASE, and Cochrane Library for randomized controlled trials, clinical trials, and case studies published within 5 years. The articles relate to PD-1/PD-L1 inhibitors combined with chemotherapy or PD-L1 immunotherapy for triple-negative breast cancer. The results found that PD-L1 immunotherapy treatment in combination with other forms of traditional cancer therapy, such as radiation and chemotherapy, had a slightly significant positive response. However, the treatment was overwhelmingly successful in patients who exhibited PD-L1 positive TNBC compared to patients who were PD-L1 negative. Secondly, and a major concern for immunotherapy treatment is the adverse events, potentially developing autoimmune diseases. From the articles pulled, there seemed to be no new adverse events that developed for patients outside the standard toxic effects found from radiation and chemotherapy treatment.https://openworks.mdanderson.org/rmps/1004/thumbnail.jp

    1,830

    full texts

    4,211

    metadata records
    Updated in last 30 days.
    OpenWorks @ MD Anderson
    Access Repository Dashboard
    Do you manage Open Research Online? Become a CORE Member to access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard! 👇