OpenWorks @ MD Anderson
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Sunset Coast, canvas close-up
Artist: Leni Mathews
Materials: Wood, cardboard, leftover yarn, paint, gluehttps://openworks.mdanderson.org/recycledart2025/1004/thumbnail.jp
Ionizing Radiation’s Effects on DNA and Its Correlation with the Development and Incidence of Leukemia: A Meta-Narrative Review.
Exposure to ionizing radiation, particularly gamma radiation, has been linked to chromosomal damage that may lead to the development of Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia (CML). This meta-narrative review analyzes existing literature to better understand the dose-dependent effects of radiation and how they influence leukemia risk across different populations. A total of 11 studies were synthesized for the review. The review draws from studies published between 2020 and 2025, while also incorporating historical data from the 1940s, including research on survivors of the Hiroshima and Nagasaki atomic bombings. Data was collected through targeted searches of peer-reviewed literature, focusing on studies that examined radiation dosage, chromosomal abnormalities, and leukemia subtypes. AML is more frequently linked to prolonged, high-dose exposure, which often results in widespread DNA damage and insufficient repair. In contrast, CML is more commonly associated with lower, repeated doses and is often marked by the (9;22) chromosomal translocation. Age appears to be a consistent factor in both risk and prognosis, with increasing exposure over time corresponding to higher incidence and lower survival rates. Although findings related to gender, race, and ethnicity remain inconsistent, the meta-narrative review highlights the value of early genetic screening and long-term monitoring in at-risk groups. These insights support the need for re-evaluating radiation exposure thresholds and enhancing public health practices to better address the long-term effects of ionizing radiation.
Cytogenetics Technology Program, School of Health Professionshttps://openworks.mdanderson.org/rmps25/1001/thumbnail.jp
Making Training Stick: Transferring Learning Back to the Job
Communication remains a central priority in healthcare, making it a key component of many training efforts. The positive impacts of communication training in healthcare settings have been well-established; however, the linkage of communication training to key organizational outcomes (e.g., engagement, performance, retention) remains underexplored. The present study investigated a training program targeting interpersonal communication within a large academic oncology center. We drew from Cognitive Load Theory and Social Cognitive Theory to evaluate the impact of the training on participant learning (retention and utilization), transfer (communication, decision-making, performance), and results-level outcomes (engagement and turnover). The program centered around a personality framework and maximized adult learning principles. Our sample consisted of 6,999 employee participants and a matched control sample of 6,741 employees who did not participate in the training. As hypothesized, trainees remembered and utilized the personality framework from the training program more in comparison to other personality assessments. Our findings also supported greater employee engagement, performance, and retention in comparison to the control group. An agenda for future research and implications for practice are discussed
Overcoming Barriers: Reducing Prostate Cancer Disparities for Black Men
https://openworks.mdanderson.org/rmps25/1000/thumbnail.jp
Library News October 2025
Celebrating American Archive Month Discover IEEE Xplore: A Powerful Resource for Cancer Researchers Remote and Hybrid Work: Refreshing Yourself and Your Environment A Little Distraction from the Day\u27s Tasks: Learn the Meaning of dishttps://openworks.mdanderson.org/rmlnews25/1009/thumbnail.jp
Improving Implanted Electronic Device Management in Radiation Oncology
https://openworks.mdanderson.org/acif26/1001/thumbnail.jp
The Pause After the Pulse: Learning from a Code Blue Debrief
A structured multidisciplinary after-hours code debrief was utilized to learn from identified safety gaps by using psychological safety, peer support, mock codes and badge inserts utilizing cognitive aids. Overall impact is improved safety, process reliability, team cohesion, and psychological safety aligned with organizational values.https://openworks.mdanderson.org/acif26/1003/thumbnail.jp
Improving Influenza Vaccination Assessment at the General Internal Medicine Clinics
To highlight an impactful quality-improvement initiative focused on strengthening influenza vaccination assessment within the General Internal Medicine clinics. Because patients with cancer face a significantly higher risk of complications from influenza, ensuring accurate vaccination assessment and documentation is not just important—it is essential to their safety and well-being.https://openworks.mdanderson.org/acif26/1006/thumbnail.jp
Image-Guided Mechanistic Modeling of Stereotactic Radiosurgery Used in Combination with Immune Checkpoint Blockade
December 11, 2025
Caroline Chung, MD Professor, Dept. of Radiation Oncology VP, Chief Data & Analytics Office, Data Impact & Governance, MD Anderson Cancer Center
Joseph D. Butner, PhD Assistant Professor, Dept. of Radiation Oncology, MD Anderson Cancer Center
Alexander Silalahi, PhD Research Investigator, Dept. of Radiation Oncology MD Anderson Cancer Center
Andrew Elliott, PhD Data Scientist, Dept. of Radiation Oncology MD Anderson Cancer Center
Bikash Panthi, PhDData Scientist, Dept. of Radiation Oncology MD Anderson Cancer Centerhttps://openworks.mdanderson.org/igct_seminars/1027/thumbnail.jp
Targeting Melanoma Prevention Through Geospatial and Community Level Risk Assessment in Underserved Texas Communities
https://openworks.mdanderson.org/soar25/1001/thumbnail.jp