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The Effect Of Watts-Strogatz And Barabási-Albert Graphs On Memory Formation
No full textUnderstanding higher level cognitive processes is a central problem in neuroscience. The Neuroidal model provides a useful framework for posing these problems in a computer science context. There has been significant recent work trying to understand memory capacity in the Neuroidal model but this work was done assuming that the network of neurons was an Erdos-Renyi random graph. However the network of neurons in the brain has been shown to exhibit small-world properties, which are not present in Erdos-Renyi graphs. In this research we explore replacing Erdos-Renyi graphs with Watts-Strogatz and Barabasi-Albert graphs in order to more accurately model the biological reality. We aim to investigate the implications for memory capacity and interference within the Neuroidal model
Molecular Mechanisms Associated With Mastitis In Dairy Cattle
No full textMastitis, the inflammation of the mammary gland caused by both gram-positive and gram-negative bacteria, causes the global dairy industry over $20 billion annually in losses due to changes in milk yield and quality. The goals of this research were to 1) identify genetic variants, genes, and biological pathways that are associated with mastitis, and 2) identify genetic variants, genes, and biological pathways that are associated with somatic cell count. In Chapter 3, we describe genome-wide association studies (GWAS) on 1,858 cows from two lactations with both medium (n=87,493) and high density (n=624,300) single nucleotide polymorphisms (SNP) using a single SNP mixed linear model. A total of 289 SNPs across all models reached genome-wide significance at 5% false discovery rate (FDR) and were mapped to 100 different nearby genes which have been identified in previous studies and are quantitative trait loci for somatic cell count. Significant SNPs and genes were mapped to the bovine genome to reveal corresponding genes to allow gene enrichment analysis to identify significant biological pathways associated with mastitis. In Chapter 4, we describe genetic associations affecting lactation average somatic cell count using 624,300 single nucleotide polymorphisms (SNP) on performed on 364 Holstein and Jersey cows in their first lactation. A total of 205 SNPs reached genome-wide significance at 5% FDR and were mapped to 68 unique genes
Filter: Framework For Integrated Legislative Transparency And Exploratory Research
Get PDFDigital Democracy, established at Cal Poly\u27s Institute for Advanced Technology and Public Policy, initially provided users access to a distinctive dataset, including state legislative committee hearings, transcripts, videos, and more. However, the discontinuation of funding ended operations for the project and emphasized the need for a streamlined application independent of third-party dependencies and capable of offering real-time and organized access to the invaluable Digital Democracy dataset. We introduce FILTER, a cloud-hosted API designed for read access to the Digital Democracy dataset through twelve distinct endpoints. The system contains two databases: the Digital Democracy Database (DDDB) and the Digital Democracy Knowledge Graph (DDKG). The latter, designed after DDDB, utilizes the advantages of a graph data structure for efficient data retrieval and novel knowledge discovery. This thesis is a comprehensive resource, providing detailed documentation and architectural design specifications for FILTER. The study outlines the API\u27s design, functionality, and pipeline developed for maintaining DDKG. Furthermore, the thesis presents rigorous API performance evaluations, compares the efficiency of the two databases under significant loads on the API, and a series of case studies showcasing the unique insights derived from analysis performed on the novel DDKG dataset
Hydropower Collegiate Competition
Get PDFAs part of our team’s participation in the 2024 Hydropower Collegiate Competition, our team constructed and iterated a small-scale Kaplan turbine using a custom-designed test rig and dynamometer. While our model was vastly simplified from what is used in the real world, the process gave us exposure to design procedures and hydrological techniques for turbine design. Crucially, we learned that while analytical models and theory are valid tools as starting points, the use of computational and experimental models is key to developing sound designs.
In the end, our group was able to produce a Kaplan turbine with a peak efficiency of 3.2% at a power output of just over 1 Watt. However, the aim is that future students will be able to continue and refine our work using some of our existing knowledge on turbine design as well as our experience within the competition
LiftWalker
Get PDFThe LiftWalker’s purpose is to lift users with degenerative diseases from a seated to standing position and support them as they practice the motion of walking as a form of physical therapy. The current LiftWalker is upward of 250 while still fulfilling the sponsors requirements to comfortably raise a 250 lbs. user 2 feet - the typical change in height when transitioning from sit to stand - in a controllable fashion. An accompanied therapy aid can reasonably steer, lift, and adjust the user during use
Rapid Composter
Get PDFThis Final Design Review documents the efforts of a team of mechanical engineering students from California Polytechnic State University, San Luis Obispo as they work towards completing their assigned senior design project. This team was tasked with designing and developing an onsite rapid composter for the Girl Scouts of California’s Central Coast. The selected design concept that will be explained focuses on creating a composter that is child-safe, portable, weatherproof, solar-powered, and requires minimal manual user input. This report will not only provide a detailed description of the chosen design but will also supply an extensive design justification. This mainly includes quantitative analysis performed by the team. Additionally, this report will detail the intended manufacturing plan for the composter design. Related appendices including the project budget, design hazard checklist, and design verification plan are provided to ensure the sponsor, Girl Scouts of California’s Central Coast, is satisfied with the final design
AS-969-24 Resolution on the Senate Curriculum Appeals Committee Membership and Appeals Process
Get PDFAdopts the attached revisions for modifying the bylaws of the Academic Senate regarding the Curriculum Appeals Committee and the Appeals Process as described below