Scholarship@Western

Purkis, Christopher

Western University 
Scholarship@Western 
Inspiring Minds – Showcasing Western’s Graduate Research, Scholarship and Creative Activity 
September 2021 
Association between Testosterone, Androgen Receptor 
Polymorphisms, and Mood 
Christopher Purkis 
Western University, cpurkis@uwo.ca 
Follow this and additional works at: https://ir.lib.uwo.ca/inspiringminds 
Citation of this paper: 
Purkis, Christopher, "Association between Testosterone, Androgen Receptor Polymorphisms, and Mood" 
(2021). Inspiring Minds – Showcasing Western’s Graduate Research, Scholarship and Creative Activity. 
218. 
https://ir.lib.uwo.ca/inspiringminds/218 
Association between Testosterone, Androgen Receptor Polymorphisms, and Mood 
The hormone testosterone (T) plays many important roles in the male nervous system; however 
little is known about its role in mood. Recent findings suggest that insufficient T activity in the 
brain may contribute to negative affect in men. Furthermore, some evidence indicates that 
structural variations in the Androgen Receptor (AR), the primary receptor to which T binds, may 
also contribute to mood regulation and potentially to an increased risk for depression.  However, 
there has been little research on this topic. My proposed study will investigate the relationship 
between T levels, AR variants, and negative affect in healthy young men to explore whether low 
T and/or AR variants are associated with greater affective negativity. I will also investigate AR 
variants among demographically matched males who are receiving treatment for depression to 
determine whether AR may confer increased risk. This work will advance our understanding of 
testosterone’s role in emotional regulation. 
 


English

Association between Testosterone, Androgen Receptor Polymorphisms, and Mood

Terek, Julia

Western University 
Scholarship@Western 
Inspiring Minds – Showcasing Western’s Graduate Research, Scholarship and Creative Activity 
September 2021 
Developing biomaterials for brain regeneration 
Julia Terek 
Western University, jterek@uwo.ca 
Follow this and additional works at: https://ir.lib.uwo.ca/inspiringminds 
Citation of this paper: 
Terek, Julia, "Developing biomaterials for brain regeneration" (2021). Inspiring Minds – Showcasing 
Western’s Graduate Research, Scholarship and Creative Activity. 220. 
https://ir.lib.uwo.ca/inspiringminds/220 
I had a grandmother who passed away at 65 due to an aggressive, incurable neurodegenerative 
condition which shares some similarities with the more commonly known Parkinson’s disease. This 
inspired me to actively pursue research in the field of tissue engineering, to help develop novel 
therapies for patients with limited treatment options. My project is focused on developing biomaterials 
for brain regeneration. More specifically, I am working on developing a scaffold fabricated from 
extracellular matrix, the natural framework that is present in all tissues in the body. This scaffold, 
derived from brain tissue, can be used to support the growth and expansion of brain stem cells, which 
have the capability to specialize into different cell types of the brain. These cells can eventually be 
delivered to the patient to promote regeneration in the damaged areas of their brain, and hopefully 
reverse the effects of neurodegenerative disease.  


Developing biomaterials for brain regeneration

Arjaliès, Diane-Laure

Casa Nova, S.P.C.

Gendron, Y.

Lehman, C.

Navarro Pérez, P.A.

Resende de Lima, J.P.

Stoner, G.

Vera-Colina, M.A.

Full Issue / Édition Complète / Edição Completa / Edición Completa

Hoang, Lyn N

Western University 
Scholarship@Western 
Inspiring Minds – Showcasing Western’s 
Graduate Research, Scholarship and Creative 
Activity 
Inspiring Minds 
September 2021 
Working in the platform economy 
Lyn N. Hoang 
Western University, lhoang3@uwo.ca 
Follow this and additional works at: https://ir.lib.uwo.ca/inspiringminds 
Citation of this paper: 
Hoang, Lyn N., "Working in the platform economy" (2021). Inspiring Minds – Showcasing Western’s 
Graduate Research, Scholarship and Creative Activity. 86. 
https://ir.lib.uwo.ca/inspiringminds/86 
Lyn Hoang – 250 563 706 
 
Working in the platform economy 
 
In 2018, a 7-year-old boy earned US$22 million dollars from his YouTube videos demonstrating 
that influencer can be a profitable career. Increasingly, more people are earning incomes through 
other digital platforms like sharing their home on Airbnb, or vehicle on Uber. Yet is work in this 
platform economy just a side hustle to earn extra money? Or does it indicate a more permanent 
trajectory of work that is not salaried and fulltime? Given that one-in-five Canadians work in the 
platform economy, it is necessary to uncover any potential impacts, challenges and consequences 
that stem from working in this economy. Even more, this industry is operating in a grey area not 
entirely covered by current regulations and policies. The findings from this research can be used 
to inform the construction of evidence-based policies that can better regulate the platform 
economy and provide protections for workers. 
 
 


Working in the platform economy

https://ir.lib.uwo.ca/clinicalskills_abdominalexam/1023/thumbnail.jp

Arthur Labatt Family School of Nursing

Bowel Sounds - SP001 - Right Upper Quadrant

Cleaning Stethoscopehttps://ir.lib.uwo.ca/edu_nursing/1001/thumbnail.jp

Faculty of Nursing, Western University

Cleaning Stethoscope

Anterior Right Lower Lobe Assessmenthttps://ir.lib.uwo.ca/clinicalskills_respexam/1010/thumbnail.jp

Anterior Right Lower Lobe Assessment

Anterior Left Upper Lobe Assessmenthttps://ir.lib.uwo.ca/clinicalskills_respexam/1008/thumbnail.jp

Anterior Left Upper Lobe Assessment

Left Anterior Lobe Assessmenthttps://ir.lib.uwo.ca/clinicalskills_respexam/1005/thumbnail.jp

Left Anterior Lobe Assessment

Right upper lobe full viewhttps://ir.lib.uwo.ca/clinicalskills_respexam/1019/thumbnail.jp

Western University

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