Revistas de Investigación UNHEVAL (Universidad Nacional Hermilio Valdizán de Huánuco)
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Diagnóstico de arritmias ventriculares en pacientes con síndrome post COVID-19
Get PDFObjective. To identify ventricular arrhythmias in patients suffering from this disease (post VOCID-19 syndrome). Materials and methods. Descriptive, prospective and cross-sectional study. The sample corresponded to 79 patients infected by VOCID-19 diagnosed, treated and discharged from a Venezuelan institution. The most important study variables were: severity by VOCID-19 and types of ventricular arrhythmias. A data collection instrument validated by expert judgement was used. Rhythm Holter was used for cardiovascular evaluation. Descriptive statistics and graphs-figures were used. Results. 45.57% of the patients were female and 54.43% male, the average age was 56 years, with predomium of the age group between 41 and 60 years (49.4%). According to the symptomatology, 31.65% of the patients had a mild disease, 59.5% moderate and 8.86% severe. The most frequent types of arrhythmias according to the type of VOCID-19 suffered were: sinus rhythm (28%) in mild cases; sinus tachycardias (26%) and inappropriate (26%) for moderate cases and ventricular tachycardia (43%) in severe cases. As for the clinical evolution of the patient, in the process of mild disease the evolution was satisfactory of 100%; in the moderate the evolution was 88.5%, and in the severe 16.6%. Conclusion. Holter was able to determine the type of arrhythmia suffered by patients, which was different according to the degree of severity of the disease, so this information could be considered as a predictive factor.Objetivo. Identificar arritmias ventriculares en pacientes que padecieron esta enfermedad (síndrome post COVID-19). Materiales y métodos. Estudio descriptivo, prospectivo y transversal. La muestra correspondió a 79 pacientes infectados por COVID-19 diagnosticados, tratados y egresados de una institución venezolana. Las variables de estudio más importantes fueron: severidad por COVID-19 y tipos de arritmias ventricular. Se utilizó un instrumento de recolección de datos validado por juicio de expertos. Se empleó el Holter del ritmo para la evaluación cardiovascular. Se utilizo estadísticos descriptivos y gráficos-figuras. Resultados. El 45,57% de los pacientes fueron femeninos y 54,43% masculino, la edad promedio fue de 56 años, con predomio del grupo etario entre 41 y 60 años (49,4%). De acuerdo con la sintomatología, el 31,65% de los pacientes tuvo una enfermedad leve, el 59,5% moderada y un 8,86% severa. Los tipos de arritmias más frecuentes según el tipo de COVID-19 padecido, fueron: Ritmo Sinusal (28%) en casos leves; las Taquicardias Sinusal (26%) e Inapropiada (26%) para moderados y Taquicardia Ventricular (43%) en los casos severos. En cuanto a la evolución clínica del paciente, en el proceso de la enfermedad leve la evolución fue satisfactoria de un 100%; en la moderada la evolución tuvo un 88,5%, y en la severa de 16,6%. Conclusión. A través del Holter se pudo determinar el tipo de arritmia que padecían los pacientes, la cual fue diferente de acuerdo al grado de severidad de la enfermedad, por lo que esta información pudiera ser considerada como un factor predictivo
Reflexiones en torno a la identidad en el Perú
Get PDFOne of the fundamental discussions in Peru is about identity, it is sometimes wrong due to false recognition, people who often have an identity because they give it to them or people who often have a (false) identity product of someone making them believe that they are something determined. The paper’s mission is to bring out the aforementioned and point out the reasons that have led to it.Una de las de las discusiones fundamentales en el Perú es sobre la identidad, la misma algunas veces es errada por el falso reconocimiento, personas que muchas veces tienen una identidad porque ellas mismas se la dan o personas que muchas veces tienen una identidad (falsa) producto de que alguien les hace creer que son algo determinado. El artículo tiene como misión sacar a flote lo mencionado y señalar los motivos que han llevado a ello
Educación y participación para el desarrollo local desde una perspectiva de cuenca: caso de la cuenca del valle zaña
Get PDFLocal development from a basin perspective: the case of the Zaña valley basin” aims to describe the implementation of policies in the management of local development in the districts located in the Zaña valley basin. The central problem of our research is Is there in the local development management in the districts located in the Zaña Valley Basin a basin conception that is based on the rational use of natural resources, the development of social capital with identity and the sustainability of the environment? The object of study are the 8 districts that are located within the Zaña valley basin. It was determined that in the management of local development in the districts of the Zaña valley basin there is no basin approach. The public policies of the central government, regional and local governments are centralist and limit the spaces for participation of social actors. The need arises to incorporate a vision of account in the conception, design and implementation of public policies that values the concept of sustainability of natural resources and generates spaces and efficient mechanisms for the participation of the population.Educación y participación para el desarrollo local desde una perspectiva de cuenca: caso de la cuenca del valle Zaña” tiene como objetivo describir la implementación de políticas en la gestión del desarrollo local en los distritos ubicados en la Cuenca del valle Zaña. El problema central de nuestra investigación es. ¿Existe en la Gestión del desarrollo local en los distritos ubicados en la Cuenca del Valle Zaña una concepción de cuenca que se sustente en el uso racional de los recursos naturales, el desarrollo del capital social con identidad y la sostenibilidad del medio ambiente? El objeto de estudio son los 8 distritos que se ubican dentro de la cuenca del valle Zaña. Se llegó a determinar, que en la gestión del desarrollo local en los distritos de la cuenca del valle Zaña no existe un enfoque de cuenca. Las políticas públicas del gobierno central, los gobiernos regionales y locales son centralistas y limita los espacios de participación de los actores sociales. Se plantea la necesidad de incorporar una visión de cuenta en la concepción diseño e implementación de las políticas públicas que valore el concepto de sustentabilidad de los recursos naturales y genere espacios y mecanismos eficientes de participación de la población
Antibiogram of Bacteria Isolated from Patients with Lower Respiratory Tract Infection at the general outpatient department of some hospitals in Kebbi State, Nigeria
Get PDFThe rise in antibiotic resistance could be a growing public health concern among agents of respiratory tract infection, which is liable for morbidity, mortality, and costs in Africa. This study was designed to determine the antimicrobial susceptibility pattern of bacteria isolated from patients with lower respiratory tract infection (LRTI) attending some Kebbi State, Nigeria hospitals. Three hundred and fifty sputum samples were collected from consented patients with the symptoms of LRTI attending six different hospitals in Kebbi State. The samples were all screened for significant bacterial growth using standard microbiological techniques. The bacterial isolates were identified using conventional biochemical tests and then confirmed using a commercial biochemical test kit (MICROBACT) according to the manufacturer\u27s instructions. Antimicrobial susceptibility tests were identified using the disc diffusion method. Staphylococcus aureus was the foremost predominant bacteria isolated, followed by Klebsiella pneumoniae, with an estimated percentage occurrence of 31.1% and 22.2%, respectively. Other bacteria isolated include Klebsiella oxytoca (13.9%), Escherichia coli (11.1%), Pseudomonas aeruginosa (5.6%), Aeromonas hydrophila (5.6%), Acinetobacter baumannii (4.6%), B. pseudomallei (2.8%) and Proteus spp (2.8%). Most of the isolates were ssusceptible to piperacilin (51%), trimethoprim-sulfamethoxazole (61%), Azithromycin (70%), Ciprofloxacin (71%) and Gentamycin (74%), so as of ranking. High resistance was recorded in βeta-lactam antibiotics, erythromycin and vancomycin tested. Finally, it was revealed that Staphylococcus aureus is the most predominant bacteria isolated. Most of the isolates were resistant to the β-lactam antibiotic tested. Azithromycin, Ciprofloxacin, Gentamycin, and piperacillin remain helpful antibiotics for treating LRTIs in these centers
Evaluating the Effects of Umifenovir Compared to Lopinavir/Ritonavir in the Management of Patients with COVID-19: A Randomized Controlled Trial
Get PDFBackground. Due to the lack of specific safe medications for the treatment of COVID-19, medications used for other similar conditions are being tested to alleviate the condition of COVID-19 patients, resulting in acceptable outcomes in some cases. Umifenovir (Arbidol®) is used to treat influenza viruses by inhibiting the fusion of the virus with the host cell. According to previous findings, umifenovir may inhibit SARS-CoV-2 infection by interfering with the release of SARS-CoV-2 from inside the cell. This study aimed to determine the effects of umifenovir, a fusion inhibitor, versus lopinavir/ritonavir in treating patients with COVID-19. Methods. This study was a randomized controlled trial consisting of 90 confirmed COVID-19 patients divided into the lopinavir/ritonavir group and the umifenovir group. The lopinavir/ritonavir group received 100/25 mg twice, while the umifenovir group was given 200 mg thrice a day, in both groups, for seven days. Outcomes included mortality rate and the need for mechanical ventilation or intensive care unit admission. Length of stay in the hospital and ICU and the lab tests trend were also assessed. Results. The mortality rate and the need for admission to the ICU were significantly lower in the umifenovir group (8% vs. 27.5%; P-value = 0.02). Moreover, The levels of white blood cells were also lower in the umifenovir group than in the control group by day 10 (6.2 (5.3-7.4) vs. 10.8 (9.9-13); P-value <0.001). Conclusions. Umifenovir may reduce the need for admission to the ICU and mortality rate in patients with COVID-19 compared with lopinavir/ritonavir. The lab test trends were also in favor of umifenovir use.
New molecular mechanisms related to drug resistance in tuberculosis
Get PDFDespite the global efforts tuberculosis (TB) remains as one of the most important infectious disease and with the greatest impact on global public health, this situation has been aggravated in recent decades by the growing problem of drug resistance (DR). Such is the impact of the drug resistant in tuberculosis that would threaten the Millennium Development Goals. In addition to polymorphisms in genes associated with drug resistance in tuberculosis, new mechanisms have being described in recent years. Considering the above, the aim of this mini-review is to give a brief description of the traditional mechanisms related with drug resistance and to describe two of the new mechanisms that will have an important impact in the next future; efflux pumps and DNA damage repair mechanisms
Regeneración ósea post exodoncia por fractura dentaria de origen traumático
Get PDFThe present article aims to report a clinical case that exposes the guided bone regeneration treatment (ROG) in a tooth with a traumatic fracture. The procedure consisted of bone regeneration, which has proven to be a successful technique to promote the recovery of dentoalveolar bone defects. Lyophilized organic bovine bone and resorbable bovine collagen membrane were placed one month after having suffered a dentoalveolar trauma at the level of the upper right central incisor. In conclusion, the treatment proved to be very effective in increasing and preserving the dimensions of the resorbed alveolar ridges, optimizing the biological conditions of our patients for subsequent rehabilitation.
El presente artículo tiene como objetivo reportar un caso clínico que expone el tratamiento de regeneración ósea guiada (ROG) en una pieza dentaria con fractura de origen traumático. El procedimiento consistió en regeneración ósea, la cual ha demostrado ser una técnica exitosa para promover la recuperación de defectos óseos dentoalveolares. Se colocó hueso orgánico de bovino liofilizado y membrana reabsorbible de colágeno bovino a un mes de haber sufrido un trauma dentoalveolar a nivel del incisivo central superior derecho. En conclusión, el tratamiento demostró ser muy eficaz para aumentar y conservar las dimensiones de los rebordes alveolares reabsorbidos, logrando optimizar las condiciones biológicas de nuestros pacientes para una posterior rehabilitación.O procedimento de regeneração óssea guiada (ROG) tem se mostrado uma técnica de sucesso para promover a regeneração de defeitos ósseos presentes ao redor dos implantes dentários, bem como para aumentar as dimensões vertical e horizontal das cristas alveolares atróficas antes da colocação do implante. O plano de tratamento incluiu a instalação de osso bovino orgânico liofilizado e uma membrana de colágeno bovino reabsorvível após um mês de trauma dentoalveolar. O objetivo deste relato de caso é descrever a instalação do osso liofilizado e da membrana, após ter sofrido um trauma alveolar dentário ao nível do dente 1.1. Este artigo relata um caso clínico que expõe o tratamento de regeneração óssea guiada para a posterior instalação do implante dentário e a futura restauração da coroa
Análisis de la capacidad de carga turística como estrategia para la gestión de un aviturismo sostenible
Get PDFObjective: to determine the tourist carrying capacity through the analysis of the current concept; identifying the necessary propositions and explaining the sufficient meaning for the strategic management of sustainable and sustainable avitourism in Colombia, which has an important potential for diversification. Method. The methodology of documentary analysis and the technique of tracking, indexing, annotation, extraction, organization, translation and systematization of reviews of articles and electronic documents were applied, establishing the convergences and divergences of the theoretical and methodological constructs assumed in the ways of understanding, describing and evaluating the tourist carrying capacity of avitourism. Results: In the literature reviewed, the most referenced theoretical and conceptual approaches to tourism carrying capacity applied to avitourism are identified, as well as some of the scopes and limitations of the methodological models used and an approach to the analysis of this method from a multidisciplinary perspective. Conclusion. It concludes with the determination of the key and essential elements that should be present in the tourist carrying capacity as a tool for the management of sustainable bird watching tourism.Objetivo. Determinar la capacidad de carga turística mediante el análisis del concepto vigente, identificando las proposiciones necesarias y explicando el significado suficiente para la gestión estratégica del aviturismo sostenible y sustentable en Colombia, que cuenta con un potencial importante de diversificación. Métodos. Se aplicó la metodología de análisis documental y la técnica del rastreo, indización, anotación, extracción, organización traducción y sistematización de reseñas de artículos y documentos electrónicos, estableciendo las convergencias y divergencias de los constructos teóricos y metodológicos asumidos en los modos de comprender, describir y evaluar la capacidad de carga turística del aviturismo. Resultados. En la literatura revisada se indentifican los enfoques teóricos y conceptuales más referenciados con respecto a la capacidad de carga turística aplicada al aviturismo, así como se indican algunos de los alcances y limitaciones de los modelos metodológicos utilizados y se realiza una aproximación al análisis de este método desde una perspectiva multidisciplinar. Conclusión. Se concluye con la determinación de los elementos claves y esenciales que, deben estar presentes en la capacidad de carga turística como una herramienta para la gestión de un aviturismo sostenible
El gusano barrenador (Opogona sp.) Lepidoptera- Tineidae y sus plantas hospederas, en Satipo – Perú
Get PDFOpogona sp. it is a pest that has not been identified in Peru, despite being present in many crops for years; the objective was to evaluate the habits, damage and hosts of the larval stage. An evaluation of cultivated and wild plants in the Satipo area was carried out through field visits and inspections, observing the damage caused by the larva in the stems and opening them with a knife. The results show that the larva is eruciform, reaches 43 mm long by 4 mm wide, the cephalic capsule is globose, dark brown to black, with a pair of short mandibles. It presents darker coloration in the first three segments of the body and a pair of transverse bands in each somite. The larva eats the bark by ringing the stem, which it protects with sawdust and droppings glued with silk threads; it makes a hole about 6 to 10 cm long and vertical in the stem where it lives, when pulling it it grabs it with its false legs, it presents photophobia; the damage manifests itself as ringing of the bark and a hole inside the stem that can measure between 5 and 10 cm long; the plant may show yellowing, but does not die. 9 cultivated plants and 2 wild plants have been found as hosts; 6 are woody and 5 herbaceous; of the families Rutaceae, sterculiaceae, lauraceae, fabaceae, passionflower, rosacea, euphorbiaceae and asteraceae, being the kudzú the most frequent host.Opogona sp. es una plaga que no ha sido identificada en el Perú, pese a estar presente en muchos cultivos desde hace años; el objetivo fue evaluar los hábitos, daños y hospederos del estado larval. Se realizaron evaluaciones en plantas cultivadas y silvestres de la zona de Satipo, mediante inspecciones de campo, abriendo los tallos con una navaja y observando los daños que hace la larva en los tallos. Los resultados muestran que la larva es de tipo eruciforme de 43 mm de longitud por 4 mm de ancho, con cápsula cefálica de forma globosa y color marrón oscuro a negro, con mandíbulas cortas, presenta coloración oscura en los tres primeros segmentos del cuerpo y un par de bandas trasversales en cada somito. La larva come la corteza anillando alrededor del tallo, el cual protege con el aserrín y excremento pegado con hilos de seda; hace un orificio de unos 6 a 10 cm de largo y vertical en el tallo donde vive, al ser jalado se sujeta con sus patas falsas, presenta fotofobia; los daños se muestran como anillado de corteza y orificio dentro del tallo que llega a medir entre 5 a 10 cm de largo; la planta puede mostrar amarillamiento, pero no muere. Se ha encontrado como hospederos a 9 plantas cultivadas y 2 silvestres; 6 son leñosas y 5 herbáceas; de las familias rutáceas, esterculiácea, laurácea, fabáceas, pasiflorácea, rosácea, euforbiácea y asterácea, siendo el kudzú es el hospedero más frecuent