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Multiscale modeling approach to assess the impact of antibiotic treatment for COVID-19 on MRSA transmission and alternative immunotherapy treatment options
No full textMethicillin-Resistant Staphylococcus Aureus (MRSA) infection can occur alongside or following COVID-19, which is a concern in healthcare settings. The effectiveness of antiviral treatments for COVID-19 depends on a functioning immune response, but antibiotics used for bacterial infections like MRSA can disrupt the immune response and reduce the effectiveness of antiviral treatments. The emergence of MRSA due to excessive antibiotic usage has led to the widespread use of vancomycin as an alternative treatment. Immunomodulatory antibiotics like azithromycin may also be considered. To study the dynamics of these coinfections, a multiscale model was developed. Parameter estimation and sensitivity analysis were performed, revealing influential parameters affecting the reproduction number. Numerical simulations showed that methicillin may increase the population of co-infected cells, while azithromycin can improve the host immune response but has limited impact on MRSA proliferation. Increased efficacy of vancomycin can lead to MRSA eradication. Combination of immunomodulatory antibiotics and vancomycin has minimal effect on co-infected cell population, but increased vancomycin efficacy can reduce coinfection severity. This study emphasizes the importance of continuous research, surveillance, and the development of effective strategies to combat the complexities of COVID-19 and MRSA coinfection
The minimal invasion speed of two competing species in homogeneous environment
No full textBiological invasion has become an important element of global changes. In this paper, we use a reaction-diffusion system to discuss the minimal invasion speed of two competing species in the homogeneous environment. The general condition for the minimum invasion speed is obtained by applying the theory of propagation dynamics. Then the explicit conditions are derived by constructing upper solutions. The analytical results are corroborated by simulations of the considered reaction-diffusion system. Our results reveal the impact of the diffusion rate, growth rate, competitiveness of the species, as well as the carrying capacity of the environment, on the invasion speed, which provides an effective method for preventing biological invasion and controlling existing biological invasion
Cultural safe healthcare initiatives, implementations, and recommendations, for Indigenous peoples of Canada: a systematic review
No full textThe health of Indigenous peoples across Canada continues to be significantly impacted by experiences of racism when seeking healthcare. Implementing cultural safety was identified by the Truth and Reconciliation Commission of Canada as a critical way to mitigate these negative health consequences. This systematic review aims to outline cultural safety and its associated derivatives in academia, what cultural safety is, and why it is important in the context of indigenous healthcare. A systematic search of PubMed was carried out refining searches to Canadian contexts, published after December of 2015, and limited to peer-reviewed reviews and systematic reviews. A thematic review of the articles identified four central ideas of importance regarding the information presented in the papers; definitions of cultural safety and associated derivatives, the importance of including culture in healthcare, recommendations to healthcare settings, and evaluation methods of cultural safety initiatives. It is clear that there is a need for an explicit and consistent definition of cultural safety with the inclusion of Indigenous peoples in the creation of this definition. To determine effectiveness, gaps and areas for improvement, evaluation methods inclusive of the unique Indigenous worldviews are imperative to develop culturally safe healthcare practices and institutions. 
Were the Crusader Queens Restricted in Power? A Comparative Essay of Melisende and Sibylla of Jerusalem
No full text“Maintain the purity of German blood!”: Sexual Control in Nazi Occupied Territories, 1939-1945
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Braun, Julianne. Creole Drama. Theater and Society in Antebellum New Orleans. Charlotteville and London : University of Virginia Press, 2019
No full textSummary of the U of Virginia P: In this work by Julianne Braun, Auburn University, “moving from France to the Caribbean to the American continent, Creole Drama follows the people that created and sustained French theatre culture in New Orleans from its inception in 1792 until the beginning of the Civil War. Juliane Braun draws on the neglected archive of francophone drama native to Louisiana, as well as a range of documents from both sides of the Atlantic, to explore the ways in which theatre and drama shaped debates about ethnic identity and transnational belonging in the city”.Summary of the U of Virginia P: In this work by Julianne Braun, Auburn University, “moving from France to the Caribbean to the American continent, Creole Drama follows the people that created and sustained French theatre culture in New Orleans from its inception in 1792 until the beginning of the Civil War. Juliane Braun draws on the neglected archive of francophone drama native to Louisiana, as well as a range of documents from both sides of the Atlantic, to explore the ways in which theatre and drama shaped debates about ethnic identity and transnational belonging in the city”
Ideal Types and Ideal(ized) students in Internationalized Post-secondary Pedagogy
No full textThis article explores the relevance of Weber’s sociocultural concept of ideal types in the context of modern Canadian post-secondary education. Ideal types are simplified or distilled representations of socio-cultural values, with relevance to various social (Prandy, 2002) and educational (Hayhoe, 2007; Hayhoe & Li, 2017; Wong & Chiu, 2021) analyses. This article builds upon Hayhoe and Li’s (2007) comparison of Confucian and Western ideal types, focusing on implications for internationalized education and implicit values within. The article explores the caveats of reductive thinking regarding cultures, particularly considering culture as a proxy for race where values differ. It revisits research exploring Western students studying in an East Asian context and East Asian students studying in a Western context (Chen, 2014; Maton & Chen, 2020), using ideal types as an analytical lens for underlying values and gaps in expectations. Specifically, it considers the pedagogical implications of the differing educational cultures and values as represented by Western and Confucian ideal types, and how a broader appreciation might supplement teaching approaches founded on either type to be more inclusive and beneficial for the various learners in Canadian higher education.