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Infrastructure for Decision Capture Platform Using Dictionary Pronunciation
No full textThis working paper describes a digital documentation infrastructure for recording how individuals construct written words using dictionary-based pronunciation as a fixed reference point. Anchored to Merriam-Webster pronunciation symbols, the system captures observable sound-to-print decisions, letter representations, orthographic markings, syllable construction, and learner-generated meaning explanations.
The infrastructure is intentionally non-adaptive and non-evaluative. It does not score, correct, guide, or intervene during task completion. All decisions are preserved exactly as entered, producing stable decision records that make word-construction reasoning visible after the task is complete. Analysis and instructional interpretation occur externally.
By shifting attention from spelling correctness to observable decision processes, the platform establishes a structured documentation layer suitable for instructional review, applied practice, or descriptive research. When accumulated across sessions, records may form datasets of observable decision behavior without embedding instruction, assessment, or interpretation into the system itself.
Patent pending — U.S. Provisional Application No. 63/955.653.
© 2026 Doctor Dyslexia Dude LLC. All rights reserved.This paper describes a digital documentation infrastructure for recording how individuals construct written words using dictionary-based pronunciation as a fixed reference point. Merriam-Webster pronunciation symbols anchor a structured sequence of observable decisions, including sound selection, letter representation, orthographic marking, syllable construction, and meaning explanation. The infrastructure does not score, correct, adapt, or intervene during task completion. All decisions are preserved exactly as entered, producing stable records of how learners move from pronunciation to written form without system guidance. Each completed entry generates a persistent decision record that makes word-construction reasoning visible after the task is complete. By shifting attention from spelling outcomes to observable decision processes, the system establishes a stable documentation layer for review or analysis while maintaining a strict separation from instructional interpretation
A GENETIC INTERACTION APPROACH TO DEFINE CELL ENVELOPE PATHWAYS IN ZYMOMONAS MOBILIS
No full textThe bacterial cell envelope is a key to maintaining homeostasis and a barrier to environmental stress. The Zymomonas mobilis cell envelope has been shown to play a role in tolerance to external stresses and is a promising engineering target to improve tolerance to bioenergy production conditions. However, despite its important role, the key genes and pathways required for maintaining the envelope are not fully characterized. Genetic interaction (GI) screens, in which pairs of genes are systematically perturbed, could be used to reveal gene function and pathway membership in the. Z. mobilis envelope, but no such studies have been undertaken. Here, I propose using a double knockdown approach (Double-CRISPRi) to define the genetic pathways governing the Z. mobilis cell envelope. Next, by combining Double-CRISPRi with chemical genomics, I will identify novel combinations of genetic engineering targets with diverse functions. Taken together, by elucidating cell envelope pathways and identifying combinatorial engineering targets, this work will enable rational engineering of more robust Z. mobilis strains for enhanced biofuel production
The effects of child sexual abuse on youth and the recommendations for best treatment practices of victims
No full textA seminar paper presented to the graduate faculty at the University of Wisconsin-Platteville.
In partial fulfillment of the requirement for the degree of Master of Science – Criminal JusticeThis paper provides an overview of the consequences of child sexual abuse (CSA) and the recommendations for treatment and prevention of CSA. Both national and international perspectives of parents and victims connected to CSA are covered to provide a well-rounded view of the problem. Several theories are covered to provide some background on the reasons behind CSA. These are attachment theory, ecological systems theory, feminist theory, and lifestyle exposure theory. Overall, the conclusion is that while the incidences of crime against persons are declining even one incidence of CSA can cause drastic consequences for the victims and their families and education may be the best strategy in helping parents, educators, and other human services practitioners recognize the occurrence of CSA and the best interventions to take to help that child
Creating Cosmic Context: Investigating the Impacts on Students and Families in a Montessori Elementary Classroom through the Implementation of Cosmic Task Connections
No full textThe purpose of this unconventional study was to examine the effects of creating context
regarding the Cosmic Task in the Montessori Lower Elementary classroom. The intentionally
delivered environmental (materials and structured lessons), mind/body (conversational and
behavioral), and spiritual (rituals and routines) resources for students and families created the
opportunity for self-reflection and meaning-making around the Cosmic Task. This study was
conducted with students and their families in first, second, and third grade in a mid-west urban
public magnet Montessori school. The transformational cosmological view, which supersedes
both critical and constructivist worldviews, allows for the incorporation of spiritual insights and
indigenous perspectives wherein research is both sacred and relational rather than merely data
collection. The study found that, within a Montessori Elementary school setting, conversations
and tasks that connect individuals to our collective Cosmic purpose encourage students and
families to honor their unique purpose and contributions
Real-time visibility and its effects on transportation, scheduling, and customer service operations
No full textAn Educational Project presented to the graduate faculty at the University of Wisconsin-Platteville.
In partial fulfillment of the requirement for the degree of Master of Science - Integrated Supply Chain ManagementSupply chains are continuously evolving and highly complex value networks that help organizations gain or maintain a competitive advantage. Real-time information is still lagging in many organizations' data-driven systems, leading to information gaps. Real-time visibility into products or cargo is essential for enabling managers at various points in the supply chain to make informed decisions and communicate these changes to stakeholders. Real-time visibility is attainable through various integrated data sources using the Internet of Things (IoT) in conjunction with Blockchain technology, complementing existing and future data analytics software systems, other existing technologies, and Transportation Management Systems (TMS). The purpose of this paper is to contribute to the body of research on the positive effects of real-time visibility
TARGETING CDKN1A WITH UC2288 TO ENHANCE OSTEOGENESIS: MECHANISTIC INSIGHTS, DIFFERENTIATION PATHWAYS, AND BIOMATERIAL-BASED DELIVERY STRATEGIES
No full textp21 (CDKN1A) is a regulator of the cell cycle, involved in halting cell division, coordinating DNA repair, and contributing to both senescence and apoptosis. In addition to these functions, recent evidence indicates another role in tissue repair—particularly in bone. The aim was to investigate if UC2288-medaited suppression of p21 can increase the osteogenic capacity of mesenchymal stem cells (MSCs). While UC2288 was originally developed as an anticancer agent to induce apoptosis in malignant cells, the results demonstrate that UC2288 does not compromise cell viability at moderate concentrations, indicating its potential for safe application in this context. Furthermore, MSCs treated with UC2288 expressed higher levels of key bone markers compared to untreated controls. To delineate signaling pathways that may contribute to osteogenic differentiation beyond p21 suppression, transcriptomic analysis was performed. Genes associated with the hypoxia-inducible factor-1 (HIF-1) signaling pathway were found to be upregulated in the transcriptomic data; however, subsequent validation studies did not fully corroborate these findings. Interestingly, combined suppression of HIF-1 and p21 resulted in increased expression of osteogenic marker genes. These observations suggest a potential interaction between p21 and HIF-1 signaling in regulating osteogenesis, although further experimentation is required to confirm this relationship. In the final aim, the ability of matrix stiffness to promote transdifferentiation of chondrocytes into osteoblasts was evaluated. The results demonstrated that osteogenic transdifferentiation is highly sensitive to matrix stiffness, with only a narrow range of stiffness values supporting this process. Overall, this thesis outlines a novel strategy to enhance the osteogenic capacity of mesenchymal stem cells with strong translational potential, particularly given that the therapeutic agent investigated is already approved by the FDA. Future studies will focus on in vivo validation to determine optimal dosing and treatment duration for improving bone healing following injury. Additional investigations will also assess the efficacy of this approach in pathological conditions such as advanced age, osteoporosis, and diabetes.2028-01-2
The ugliness of organizational growth: Analyzing developments which help merging organizations
No full textA seminar paper presented to the graduate faculty at the University of Wisconsin-Platteville.
In partial fulfillment of the requirement for the degree of Master of Science – Organizational Change LeadershipMerging organizations is inherent in our global sphere. As Aristotle shared: “the sum is greater than the parts on their own.” Organizational merger often involves rapid decision-making in quick succession; when there are a multitude of decisions in a short time interval, the fallout can be uglier without a pathway. In review of existing strategic frameworks, Jim Collins’s Good to Great and John Hayes’s The Theory and Practice of Change Management, the paper also unfolds a separate strategy: to unify, to focus growth, to establish leaders, to distribute influence, and to reflect on the ability to repeat a similar merger. The U.G.L.I.R. strategy is applicable in non-profit and for-profit organizations to simplify the uglier and complex organizational process of merging organizations. When reviewing non-profit mergers specifically, the study finds that the characteristics of a non-profit board of directors offer more challenges to a potential merger. In addition, for-profit intra-agency mergers are resembled by non-profit interagency mergers and vice versa. Finally, there are inherent challenges to merging nonprofit organizations, such as geography and organizing documents. Still applicable, the U.G.L.I.R. strategy shows that many non-profits demand more time and patience to fulfill a merger than a for-profit might require. Multiple mergers, in quick succession, are more common in a for-profit arena
Creating organizational resilience through demand planning
No full textAn Educational Project presented to the graduate faculty at the University of Wisconsin-Platteville.
In partial fulfillment of the requirement for the degree of Master of Science - Integrated Supply Chain ManagementThe trend of increasingly dynamic business environments for manufacturing and distribution supply chains has been well-documented over the last three decades. To adapt, supply chains are becoming more complex. The need for supply chains to increase revenues across global markets and cut costs while innovation cycles, product cycles, and technology adoption rates are shrinking, is driving the need for a more demand-centric answer. A solution that creates the resiliency necessary for a company to navigate through this chaos is the incorporation of a demand management process. Demand planning is the role or department within a company with the purpose of identifying, capturing, and disseminating this ever-changing consumer demand so supply can be adjusted, risks can be mitigated, and opportunities can be harnessed. I found the demand management solution through a systematic review of books and articles addressing the pivotal functions involved in demand management, i.e. sales and operations planning (S&OP), forecasting, and data analysis
MULTI-SCALE MODELING OF BUILDING VULNERABILITY IN WILDFIRE
No full textIn the United States, fire regimes are changing because of climate change, fire suppression, and increased ignitions. Meanwhile, the Wildland Urban Interface (WUI) is growing, exposing more people and buildings to destructive wildfires. In this thesis, I advanced understanding of how to best predict building destruction in multiple ecosystems, focusing on how landscape context and scale influence outcomes. In my first chapter, I used Convolutional Neural Networks (CNNs) to predict building destruction in eight high-intensity Sierra Nevada fires using three different imagery extents (15, 30, and 60 m). In my second chapter, I measured drivers of home destruction in the wetlands of the Atlantic Coastal Plain at 35 extents from 30 to 4,110 m and determined the optimal extent or extents for each factor. I compared models using these optimal extents to models using fixed extents to understand the influence of scale on the ability to predict destruction. In the first chapter, I found that CNNs performed very well for training fires but could not be extrapolated to other fires at any extent. The 15 and 60-m models both outperformed the 30-m model, showing that the extent used for analysis changes outcomes. In the second chapter, I found that the drivers of building destruction in these wetlands differed from drivers in other ecosystems, and that the influence of variables fundamentally changed when measured at different extents. My work in this thesis shows that the extent to which variables are measured greatly influences predictions of building destruction, and that if extent is not chosen carefully, research can lead to misleading conclusions
EXPERIENCED MULTILINGUAL LEARNERS: OVERCOME CHALLENGES TO RECLASSIFY
No full textThis literature review presents a middle school instructional unit demo designed to help
Experienced Multilingual Learners (EMLs), also referred to as Long-Term English Learners
(LTELs), in developing the academic language skills necessary for reclassification. The unit demo
is the central focus and is led by a literature review examining why many EMLs experience stalled
progress in English development despite spending years in U.S. schools. Although these students
often demonstrate proficiency in social language, their academic language development frequently
remains limited, affecting their ability to meet exit criteria for English learner programs. Research
identifies inconsistent academic backgrounds, limited access to rigorous and explicit language
instruction, and decreased motivation or engagement related to low academic confidence as
contributing factors to this stagnation. These findings directly inform the instructional design of
the unit demo lesson plans, which integrates evidence-based practices such as the SIOP framework,
structured language learning strategies, and purposeful opportunities for students to engage in
academic speaking, listening, reading, and writing within a live classroom environment. Grounded
in current research, this unit’s lesson plans demonstrate how intentional instructional design can
aid EMLs’ academic language development and promote progress toward reclassification