eCommons at Roseman University
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Lipomatosis of Nerve
Get PDFLipomatosis of nerve is a benign lesion with increased fibrofatty tissue infiltrating and surrounding nerves, usually occurring in children and young adults as a slowly progressive swelling or mass, which can clinically mimic a tumor or malignancy. Here we report a 59-year-old man who presented with pain in his right foot and a mass that has been mostly stable for years, but which seems to have grown slightly of late, and is clinically suspicious for ganglion cyst. The MRI revealed a fatty mass concerning for lipoma or atypical lipomatous tumor. Consequently, the patient underwent excisional biopsy. The H&E sections showed mature adipose and fibrous tissue infiltrating the nerve, consistent with lipomatosis of nerve. Lipomatosis of the nerve, though most common in upper extremities, can occur in a variety of locations, and providers should be aware of potentially rare presentations like this one to prevent unnecessary surgery and prevent potential nerve damage
Adverse Infusion-Related Event Severity in Oncology Patients Receiving Chemotherapy Agents vs. Immunotherapy Agents
No full textIn recent years, immunotherapy investigational drugs in cancer research has been underway in treating multiple forms of cancer due to a lower side effect profile and decreased severe infusion-reaction risk compared to conventional chemotherapy agents. The purpose of this study was to determine the infusion reaction severity among patients receiving either chemotherapy treatment or immunotherapy agents based on the CTCAE (Common Terminology Criteria for Adverse Events) scale to improve patient care outcomes.
In this intent-to-treat, retrospective observational study, a survey of patients throughout 10 Intermountain Healthcare infusion clinics was conducted to obtain documentation on patients who had received chemotherapy and/or immunotherapy agents as part of their cancer therapy course and their respective adverse events that had occurred during infusion time. Data was abstracted on a total of 295 patients, both men and women, between the ages of 2-90 years old. Among these participants, a total of 140 patients had met inclusion criteria for study enrollment. The level of severity of reaction event was determined using CTCAE scale 1-5.
Among the participants, data showed that 90 patients (0.64 percent) who had received chemotherapy agents during their cancer treatment saw infusion-related adverse effects with the level of severity among this group averaging at a 2 (reaction prompting medication intervention) compared to 50 patients (0.36 percent) who received immunotherapy. Patients who were noted to have adverse events at a level 3 severity between both groups of patients that warranted early termination of treatment and prompted immediate medical attention included 5 patients receiving chemotherapy and 1 patient receiving immunotherapy. A chi-square test of independence showed there was no statistical significance between patients who received chemotherapy and immunotherapy based on the severity of the infusion-related event X2(1, N=140) = 0.99, p \u3c0.05.
Although the findings this study were not statistically significant between patients receiving chemotherapy compared to patients receiving immunotherapy agents to effectively treat cancer diagnoses, the study did show clinical significance based on the reaction incidence and level of severity and the tolerance to treatment
Evaluation of nasal mupirocin use in intermediate medical care units at an acute care hospital
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The Current State of Underrepresented Osteopathic Minorities in Competitive Specialties
No full textIt is well documented that barriers exist for underrepresented minorities to enter the field of medicine and even more competitive residencies. As defined by the NRMP, competitive specialties include but are not limited to Interventional Radiology, Orthopedic Surgery, Plastic Surgery, Radiation Oncology, Vascular Surgery, Neurosurgery, Dermatology, and Otornylogy (NRMP-AMA). A large number of osteopathic medical school graduates have a history of going into primary care specialties because many osteopathic medical schools have a primary care focus (Primary Care- Osteopathic Medicine). The emphasis on primary care, whether intentional or not, can foster a less-than-advantageous environment for underrepresented minority students (URM), pursuing interests in competitive specialties. Furthermore, additional barriers exist for osteopathic medical students to enter these competitive specialties. This Literature review seeks to evaluate the current standings of URM osteopathic medical students in these specialties while providing recommendations to increase representation in these fields
