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The National Status of Pharmacists’ Ability to Prescribe Hormonal Contraceptives
Get PDFThe scope of practice for pharmacists first expanded in California and Oregon with the ability to prescribe hormonal contraceptives to patients in their communities. Since 2016, over 33 states now allow for pharmacist prescribing of birth control in their pharmacy practice laws.
90% of Americans live within 5 miles of a retail pharmacy, making community pharmacies an accessible resource who may otherwise be unable to access contraceptives. The gap in care experienced by certain patient populations is now being filled by pharmacists with their ability to prescribe birth control
ESTROGEN LEVEL, OSTEOPENIA/OSTEOPOROSIS AND PERIODONTAL STATUS IN POST MENOPAUSAL WOMEN – A COMPARATIVE EVALUATION
Get PDFOsteopenia, Osteoporosis and periodontitis are diseases, which affect a large number of populations across the country and world. Both are silent diseases” which cause bone loss mediated by local and systemic factors. These two diseases also share some risk factors that may interfere with healing.. Estrogen deficiency is the dominant pathogenic factor for osteoporosis in women .Various reports also have linked estrogen deficiency and osteopenia/osteoporosis to increased oral bone resorption , attachment loss and tooth loss .The objective of the study is to analyse and evaluate the condition of periodontal status of twenty five osteopenic/osteoporotic postmenopausal women and their estrogen level with twenty five non osteopenic/non osteoporotic postmenopausal women and their estrogen level
Revolutionizing Denture Excellence: An Invigorating In-Vitro Exploration of Organic Products in Prosthetic Rehabilitation
Get PDFThe denture base comes into contact with diverse substances in the oral cavity, acting as a reservoir for microorganisms like corynebacterium, streptococcus, lactobacillus, and candida. This colonization elevates the risk of complications such as denture stomatitis and candidiasis. Commercial denture cleaners have explored the use of natural ingredients, less commonly employed but offering various advantages. These ingredients aim to mitigate the potential issues associated with microbial colonization on denture surfaces, contributing to improved oral hygiene for denture wearers. The exploration of natural elements reflects a nuanced approach to denture care, considering both efficacy and less conventional alternatives
Angiofibroma of Soft Tissue: A Case Report
Get PDFDifferentiation between benign angiofibromas of soft tissue and malignant sarcomas.
The accurate diagnosis of this tumor is essential to prevent additional unnecessary treatments and/or surgeries. This can be achieved by proper genetic testing for the presence of markers including the NCOA2 fusion gene, CD34, α-SMA, and epithelial membrane antigen. Genetic testing is an essential component of accurate diagnosis as the appearance of these lesions can mimic other, more harmful neoplasms. Immunohistochemical analysis frequently shows the AHRR-NCOA2 driver mutation which is thought to be associated with t(5;8)(p15;q13), also commonly found in AFSTs. In combination, these immunohistochemical findings allow for accurate diagnosis of angiofibroma of soft tissue in any location of the body
Development of a Curriculum for Osteoporosis Education in Rural Populations
Get PDFOsteoporosis contributes to annual costs exceeding $10 billion in the U.S. due to hip fractures and is the primary cause of hospitalization among older women. Historically, geriatric populations have received inadequate education in navigating the U.S. medical system, emphasizing the importance of targeted education among the elderly. The study’s objective is to improve health literacy among the geriatric population in rural Utah by expanding their understanding of osteoporosis
Convolutional Neural Network Based Analysis - An Aid to Diagnose Bacterial and Fungal Osteomyelitis
Get PDFOsteomyelitis may be classified as Bacterial (Actinomycotic), Fungal (Mucormycotic), or combined based on the etiological agent. During histopathological examination, there is a high chance that bacterial colonies or fungal hyphae may be missed by the human eye, especially when there is a paucity of organisms. This may lead to a faulty diagnosis of the type of osteomyelitis which along with an improper treatment plan would cause further progression of the disease and various other complications. Therefore, the diagnosis of the exact etiological variant of osteomyelitis is of prime importance to design an appropriate treatment plan. In the present study, bone parameters based on the osseous changes, were used to diagnose Osteomyelitis by employing Machine Learning through Convolutional Neural Networks (CNN). No studies in literature have utilized a CNN based analysis to differentiate between Bacterial and Fungal Osteomyelitis based on the osseous changes which would help in designing an appropriate treatment plan
DNA Extraction Method Development for Solid Tissues
Get PDFAlthough germline variation testing is traditionally performed using DNA obtained from blood or other liquid samples, determining somatic variation in cancer samples requires DNA extraction directly from tissues. Additionally, epigenetic markers, such as 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are tissue-specific and change in selected disease states. However, several substances present in tissues are known to inhibit downstream reactions, including polymerase chain reaction PCR). For this project, we are assessing the quantity and quality of DNA obtained from extractions of various vital organs using 30 different commercially available DNA extraction kits to determine optimal kits for each tissue
Experimental Oximes as Organophosphate Preexposure Prophylaxis. Lessons from the Gulf War Syndrome
Get PDFThe present study was undertaken in order to determine if established or experimental K-oximes can protect from OP (paraoxon) toxicity. Rats that received only the OP were compared with those that had received oxime pretreatment before OP exposure. Best protection from paraoxon-induced mortality was observed after pretreatment with K-48. The other oximes were significantly less efficacious, but still significantly reduced the RR compared to the no-treatment group (paraoxon only). The FDA-approved agent for prophylaxis was least efficacious. The protective efficacy was unrelated to AChE inhibition
Association between vitamin D and cardiovascular disease: Findings from a national study
Get PDFABSTRACT
Introduction
Many studies have investigated the association between vitamin D and cardiovascular disease (CVD), but literature has shown various results. The aim of this study was to investigate the role of vitamin D in CVD.
Methods
Data source
The data were obtained from the 2015-2018 National Health and Nutrition Examination Survey database and included adults aged 20 years and older with a history of CVD. Descriptive statistics for participants’ demographics, vitamin D levels, CVD status, and risk factors were reported. Chi-square tests and t-tests were performed to examine differences in participant characteristics among those who had CVD and did not have CVD. Regression models were used to explore the association between vitamin D levels and CVD.
Results
A total of 9,825 participants took part in this study with an average age of 50.28 years. Majority were female (52.1%) and Non-Hispanic White (34%). Most had normal vitamin D levels (64.8%) and had never been told that they had CVD (89.5%). Individuals with vitamin D deficiency or insufficiency had a higher likelihood of having CVD than those with normal vitamin D levels.
Conclusions
Both vitamin D deficiency and insufficiency were associated with an increased risk of CVD. Healthcare professionals may consider recommending the intake of vitamin D supplements to improve and prevent cardiovascular health in adults.
Keywords: Vitamin D, cardiovascular disease, healthcare, supplements
Word count: 24