eCommons at Roseman University
Not a member yet
635 research outputs found
Sort by
Assessment of Micrometastasis in Lymph Nodes of Oral Squamous Cell Carcinoma –Attaining Excellence through Immunohistochemistry
Get PDFCervical lymph node metastasis is the most important prognostic factor in Squamous Cell Carcinoma of Head and Neck (SCCHN). Lymph node prognostic determinants hold immense significance in influencing both patient’s survival outcomes and the propensity for recurrence. The current study aimed to evaluate the diagnostic accuracy of Cyclin D1 and Pan-CK for the detection of lymph node micrometastasis in oral squamous cell carcinoma tissue sections and re-evaluate the tumor staging
Pharmacognosy and Trichomoniasis: A Scoping Review Protocol
Get PDFTrichomoniasis, also called “trich”, is the most common non-viral sexually transmitted infection (STI). Its etiological agent is the protozoan parasite Trichomonas vaginalis, against which first-line antiparasitics usually work. However, resistance is on the rise. Trich has traditionally been considered a nuisance infection, with many (particularly AMAB patients) being asymptomatic. But research in recent years has begun to unravel correlations of trichomonal infections with a myriad of comorbitidies, including infertility, cancers, the pathogenesis of AIDS, and pelvic inflammatory disease (PID). Between the rise of drug resistance and the incidence of these comorbidities, new treatments are needed. In this work, we are reviewing clinical and preclinical reports of essential oils in the treatment of trich or in the inhibition of Trichomonas growth
Exploring the Interplay between Alzheimer\u27s disease and Periodontitis: Insights from Clinical Data and Inflammatory Biomarkers
Get PDFAlzheimer\u27s disease, a complex neurodegenerative disorder marked by cognitive decline, may have a intriguing link with periodontitis—a chronic inflammatory oral condition. This study investigates the literature evidence regarding the association between Alzheimer\u27s disease and periodontitis. Our research aims to determine if individuals with periodontitis face an elevated risk of Alzheimer\u27s and if shared inflammatory pathways underlie this association
Double-Blinded Randomized Control Trial Investigating the Efficacy of Probiotic Mouth Rinse in Enhancing Oral Health
Get PDFThe efficacy of probiotic mouth rinse in enhancing oral health was investigated through a double-blinded randomized controlled trial involving 45 children aged 12 to 15 over a two-week period. Comparing probiotic mouth rinse, chlorhexidine mouth rinse, and a control group, plaque and gingival accumulation were assessed using established indices. Results indicated both probiotic and chlorhexidine groups exhibited reduced plaque compared to the control, with the probiotic group showing superior reduction in gingival inflammation. These findings suggest the potential of probiotic mouth rinse in improving oral hygiene and overall oral health
Efficacy of Bone Marrow Aspirates in Bone Regeneration Compared to Conventional Bone Grafts- A Systematic Review
Get PDFThe search for a superior bone graft substitute compared to the gold standard of harvesting autogenous bone grafts has plagued dentists for decades. With the advent of tissue engineering, the search has been aimed at bone graft substitutes with osteogenic potential, in addition to the osteoinductive and osteoconductive properties. Bone Marrow Aspirates (BMAs) has evolved as a potential adjunct to conventional bone grafts that can substantially enhance the bone regeneration potential of these materials. The present systematic review aims to explore and assess the literature on the efficacy of bone marrow aspirates in new bone formation
Change in Basic Pulmonary Function in Response to Altitude Change
Get PDFPurpose: This study aims to determine if there is a lasting effect in lung function when an individual relocates from an area of low elevation to an area of high elevation.
Methods: Our study monitored changes in pulmonary function over time after individuals moved from a region of low elevation (1,000 feet above sea level or lower) to a higher elevation area (4,500 feet above sea level in Provo, Utah). We followed incoming students to Noorda College of Osteopathic Medicine from places of elevation lower than 1,000 feet. Spirometry was used to assess forced vital capacity (FVC) and peak expiratory flow (PEF) rate. Initial testing on subjects was completed on days three and seven after arriving in Provo and repeat testing occurred monthly over the subsequent 4 months to track changes in the above markers. Test values were assigned to a confidential subject number and lung function was graphed over time.
Results: No significant changes were observed in forced vital capacity and peak expiratory flow rate over time. However, an additional discovery revealed a correlation between sex and height when compared to FVC, as well as a correlation between weight and height when compared to PEF.
Conclusions: The primary goal of this research is to deepen our understanding of how changes in elevation impact pulmonary function and how rapidly our lungs can adapt to such changes. We anticipate that this data will prove valuable for individuals relocating to higher elevations from regions of lower elevation, reassuring them that there is no significant alteration in forced vital capacity and peak expiratory flow rate
Medication Errors Among ALS Providers in the Prehospital Setting
Get PDFEMS providers administer a variety of medications to patients in the prehospital environment, and while there are numerous published studies on medication errors pertaining to the hospital environment, there are comparatively fewer studies which focus on the prehospital environment. Therefore, the purpose of this survey is to investigate the type and frequency of medication errors occurring in the prehospital environment
Photodynamic Therapy Effects in the Treatment of Residual Periodontal Pockets
Get PDFThis systematic review examined the adjunctive effect of photodynamic therapy to treat residual pockets
Smile Miles Away: Navigating the future of teledentistry
Get PDFTeledentistry is a combination of telecommunications and dentistry involving the exchange of clinical information and images over remote distances for dental consultation and treatment planning. Teledentists are capable of improving access to oral healthcare, increasing the provision of oral health care and reducing its costs. The disparities in oral health care between rural and urban areas could also be eliminated. This article analyses the origin, rationale, scope, basis and requirements of teledentistry in conjunction with current evidence available in the literature. Ethical and legal issues relating to teledentistry, as well as the future of this alternative and innovative way of providing oral health care, are also examined in this Article
Surface Modifications of Orthodontic Bone Screws - A Novel Approach
Get PDFAnchorage control plays a key role in the correction of malocclusion. With the advent of orthodontic bone screws, attaining absolute anchorage control has become hassle free. They have the advantages of low cost, simple surgical placement, and ease of removal; therefore, they are convenient in the treatment of various malocclusions. Although the clinical stability of bone screws is exceptionally high, stability of the bone screws is compromised by factors such as microbial contamination and morphological defects. To overcome this, surface modifications are introduced to enhance the stability of the bone screws